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구개편도와 아데노이드 조직의 존재가 위장의 Helicobacter Pylori 감염에 미치는 영향
조근경,이승신,심기남 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.10
Background and Objectives:Although Helicobacter pylori (H. pylori) infection is one of the major pathogenetic factors in adenoids are composed of mucosa-asociated lymphoid tisue, which is also observed in H. pylori-related gastritis, these tissues may be considered to be an extragastric reservoir for H. pylori infection. In the present study, we investigated whether H. pylori colonization in adenoid and tonsilar tissue was associated with gastric infection. Subjects and Method:This study included 38 patients aged 6 to 35 who had undergone adenotonsilectomy or tonsillectomy. Urea breath test (UBT) was performed on (CLO) test kit imediately after their removal. And Giemsa stain was used for histologic localization of H. pylori. Results:Eleven (28.9%) of the 38 patients were H. pylori-positive on UBT, eight (21.1%) were positive on CLO test, and seven (18.4%) were positive on histologic study. In either CLO test or histologic study, 12 patients were H. pylori-positive. H. pylori-positive rate on UBT was higher significantly in group with H. pylori H. pylori-negative ones. Conclusion:These results sugest that palatine tonsils may either be an extragastric reservoir for H. pylori, or a transmission route for H. pylori infection. Thus, H. pylori colonization in adenoid and tonsil tisue may be associated with H. pylori-related gastric diseases. (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 :907-12)
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배정호,이자현,조근경 대한비과학회 2006 Journal of rhinology Vol.13 No.2
Ear cartilage is an important source of graft in rhinoplasty. The majority of ear cartilage grafts are harvested from the concha of the ear. However, in some restricted cases, the tragal cartilage can be a more favorable graft source than conchal cartilage. In this report, two cases of tragal cartilage graft rhinoplasty were selected. We used the tragal cartilage for batten graft in one case, and for the shield graft in the other case. Tragal cartilage harvesting technique was fast, simple, and did not require a special dressing. The functional and aesthetic results were relatively good. There was negligible scar formation in the donor site.
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전신적 스테로이드가 비용조직에서 TGF-β 및IL-10의 발현에 미치는 영향
이승신,고영민,배정호,조근경 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.6
Background and Objectives:Etiology and pathogenesis of nasal polyps are still not fully understood. Transforming growth factor-beta (TGF-β) and interleukin-10 (IL-10)This study was aimed to evaluate the effect of systemic steroid, which is the most potent medications used for the treatment of nasal polyposis, on the expression of TGF-β and IL-10 in nasal polyps. Subjects and Method:According to the status of steroid treatment, the polyps (n= 22) removed during an endoscopic sinus surgery were divided into treatment or control groups. For treatment group, 30 mg of prednisolone per day was administered preoperatively for seven days. Eosinophil infiltration, expression and concentration of TGF-β1 and IL-10 in nasal polyps were analyzed. Results:Although there was no statistical significance, the infiltration of eosinophils decreased in the treatment group. In the imunohistochemical study, the expression of TGF-β1 decreased in the epithelial layer of the treatment group compared with that of the control group (p= 0.043). Expresion of IL-10 increased in the stromal layer of the treatment group compared with that of the control group (p= 0.008). TGF-β1 concentration measured by ELISA showed no diferences betwen each group. IL-10 concentration increased in the treatment group (p= 0.021). Conclusion:These findings suggest that systemic steroid may exert a beneficial efect on nasal polyp treatment by at least following two mechanisms:the suppression of epithelial diferentiation and proliferation, and squamous metaplasia through the down regulation of TGF-βIL-10. (Korean J Otolaryngol 2007 ;50 :501-7)
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음도 고정 시 강도 변화에 따른 일반인과 성악인 발성의 성대접촉률 변화 특성의 비교
김한수,전용선,정성민,조근경,박은희,Kim, Han-Su,Jeon, Yong-Sun,Chung, Sung-Min,Cho, Kun-Kyung,Park, Eun-Hee 대한후두음성언어의학회 2005 대한후두음성언어의학회지 Vol.16 No.1
Background and Objectives : The most important two factors of the voice production are the respiratory function which is the power source of voice and the glottic closure that transform the air flow into sound signals. The purpose of this study was to investigate the differences between trained singers and untrained controls under varying intensity at a constant vocal pitch by simulataneous using the airway interruption method and electroglottography(EGG). Materials and Methods : Under two different intensity condition at a constant vocal pitch(/G/), 20(Male 10, Female 10) trained singers were studied. Mean flow rate(MFR), subglottic pressure(Psub) and intensity were measured with aerodynamic test using the Phonatory function analyzer. Closed quotients(CQ), jitter and shimmer were also investigated by electroglottography using Lx speech studio. These data were compared with that of normal controls. Results : MFR and Psub were increased on high intensity condition in all subject groups but there was no statistically significance. Statistically significant increasing of CQ. were observed in male trained singers on high intensity condition (untrained male : 51.31${\pm}$3.70%, trained male :55.52${\pm}$6.07%, p=.039). Shimmer percent, one of the phonatory stability parameters, was also decreased statistically in all subject groups(p<.001). Conclusion : The trained singers' phonation was more efficient than untrained singers. The result means that the trained singers can increase the loudness with little changing of mean flow rate, subglottic pressure but more increasing of glottic closed quotients.
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변성완,오승하,채성원,박시내,심유진,조근경 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.7
Background and Objectives:Several investigators have developed word lists for Korean speech audiometry. Many variations audiometry. In this study, we propose new monosylabic and bisylabic word lists, whose performances can be compared with those of previous word lists, verified in clinical situations, and revised in future with proper reasons. We also report why some compromises have ben made in the words number and the phoneme frequencies of the new monosyllabic word lists. There was no compromise in those of the new bisyllabic word list. Materials and Method:The target frequencies of new lists were determined by the previous references. In the Korean dictionary, 410 famThese words were arranged in a matrix of initial consonants and vowels to met the phonetic balance condition. Results:Two monosylabic word lists were developed with abovementioned compromises for the lack of monosylabic words with final consonants. One bisylabic word list could be made without compromise. Conclusion:The arrangement method in this report has some advantages in diversifying sylable distribution and satisfying the phonetic balance condition. The new monosylabic (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 :573-8)
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