중이염 수술 자료 입력과 동시에 작성되는 자동 수술기록표 시스템의 개발

변성완,정수연,정일회,박진영 대한이비인후과학회 2012 대한이비인후과학회지 두경부외과학 Vol.55 No.1

Background and Objectives It takes considerable time and effort to make an operation record for the chronic otitis media. Also there are risks of incorrectness or omission of data. We developed an automatic operation recording system in order to reduce the burden of the resident keeping the record and to give completeness to the operation data. Materials and Method The model-view-controller (MVC) pattern isolates the domain logic (controller) from the user interface (data model-view), permitting independent development. We used the MVC pattern to design the program it since it matched with the feature of the operation recording system. Results We implemented this system using the Python programming language, which is composed of 98 fields and 4 different types of widgets linked to those fields. The outputs of the 4 views can be easily copied and pasted to the word processor and the electronic medical recorder. In the pilot test, this system reduced significant amount of time and effort needed for operation recording. Conclusion The automatic operation recording system reduces the resident’s works and the operation data loss. Furthermore, it could be applied to other types of operation records.

가중 장애 적용의 청각 손상에 대한 배상의학적 고찰

변성완,이승신,박지수,김수진 대한이비인후과학회 2013 대한이비인후과학회지 두경부외과학 Vol.56 No.9

Background and Objectives When a disability is superimposed on a previous disability, the concept of aggravation of disability should be applied. In rating the disability for hearing loss, we focused on the aggravation of disability and the methods of assessment. Subjects and Method For the past 12 years, we have provided legal advisory for 111 cases of hearing injury, for which disability had to be rated. In 11 of those 111 cases, disability was assessed in consideration of aggravation of disability. We assessed disability using three rating methods: they were based on 1) a change of hearing level from assumed normal, 2) apportionment of new hearing injury in final hearing, and 3) a change in disability rating. We evaluated for significant differences and correlations between the values obtained by each method. Results There was a significant difference between the results by the methods 1 and 2. The disability rating by the method 2 showed good correlations with those assessed by the methods 1 and 3. Conclusion When considering aggravation of disability in hearing, the method 2 could be a good alternative when the standard method 3 is inappropriate.

단음절어표의 제작에서 종성과 관련된 음소 빈도의 조정

변성완,오승하,채성원,박시내,심유진,조근경 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.7

Background and Objectives:Several investigators have developed word lists for Korean speech audiometry. Many variations audiometry. In this study, we propose new monosylabic and bisylabic word lists, whose performances can be compared with those of previous word lists, verified in clinical situations, and revised in future with proper reasons. We also report why some compromises have ben made in the words number and the phoneme frequencies of the new monosyllabic word lists. There was no compromise in those of the new bisyllabic word list. Materials and Method:The target frequencies of new lists were determined by the previous references. In the Korean dictionary, 410 famThese words were arranged in a matrix of initial consonants and vowels to met the phonetic balance condition. Results:Two monosylabic word lists were developed with abovementioned compromises for the lack of monosylabic words with final consonants. One bisylabic word list could be made without compromise. Conclusion:The arrangement method in this report has some advantages in diversifying sylable distribution and satisfying the phonetic balance condition. The new monosylabic (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 :573-8)

Molecular Diagnosis of Streptococcus pneumoniae in Middle Ear Fluids from Children with Otitis Media with Effusion

변성완,김한울,윤서희,박인호,김경효 대한소아감염학회 2015 Pediatric Infection and Vaccine Vol.22 No.2

Purpose: The long-term administration of antibiotics interferes with bacterial culture in the middle ear fluids (MEFs) of young children with otitis media with effusion (OME). The purpose of this study is to determine whether molecular diagnostics can be used for rapid and direct detection of the bacterial pathogen in culture-negative MEFs. Methods: The specificity and sensitivity of both polymerase chain reaction (PCR) and loop-mediated isothermal amplification (LAMP) to the lytA gene of Streptococcus pneumoniae were comparatively tested and then applied for pneumococcal detection in the clinical MEFs. Results: The detection limit of the PCR assay was approximately 104 colony forming units (CFU), whereas that of LAMP was less than 10 CFU for the detection of S. pneumoniae . Both PCR and LAMP did not amplify nucleic acid at over 106 CFU of H. influenzae or M. catarrhalis , both of which were irrelevant bacterial species. Of 22 culture-negative MEFs from children with OME, LAMP positivity was found in twelve MEFs (54.5%, 12/22), only three of which were PCR-positive (25%, 3/12). Our results showed that the ability of LAMP to detect pneumococcal DNA is over four times higher than that of PCR (P <0.01). Conclusions: As a high-resolution tool able to detect nucleic acid levels equivalent to <10 CFU of S. pneumoniae in MEFs without any cross-reaction with other pathogens, lytA -specific LAMP may be applied for diagnosing pneumococcus infection in OME as well as evaluating the impact of a pneumococcal conjugate vaccine against OME.

청각 손상의 신체 장애율 평가 체계의 보완: 선형 회귀분석의 적용

변성완,신승호,김소정,박지수 대한이비인후과학회 2014 대한이비인후과학회지 두경부외과학 Vol.57 No.11

Background and Objectives According to the correlation between hearing injury and McBride disability rating presented by previous studies, there are over/underestimated cases particularly in the 40 dB hearing range compared to other ranges. In this study, we reviewed the overestimated and underestimated data and propose a complementation scheme for a disability rating system by using the linear regression analysis. Subjects and Method For the past 14 years, we have provided legal advisory for 121 cases of hearing injury, for which disability had to be rated. We reviewed all but excluded 11 cases for the aggravation of disability. A regression equation was produced from a linear regression analysis that used the percent of hearing handicap (AAO-HNS/AMA-1979 formula) as an independent variable (x) and McBride disability rating (%) as a dependent variable (y), following the Pearson correlation test. Iterative calculation was performed for overestimated (18) and underestimated (8) cases. Results Appropriate disability ratings were 14% for the cases overestimated to 20% and 11% for those underestimated to 5%. Appropriate disability ratings for the 20% of overestimated cases were changed to 14%, and for the 5% of the underestimated cases, the disability ratinb 11%. Iterative calculation showed that the Pearson correlation index was improved from 0.8866 to 0.9065 and the determination coefficient of regression analysis (adjusted R-square) was improved from 0.784 to 0.8202. Conclusion The common range of hearing injury, which falls between 30-40 dB corresponds to the percentage of hearing handicap of 7.5-22.5%. A fairer assessment of ability rating would be possible by complementing some parts of this hearing range. Korean J Otorhinolaryngol-Head Neck Surg 2014;57(11):748-51

지방세의 전문화·선진화를 위한 지방세제 개편안

변성완 한국지방재정학회 2008 한국지방재정학회 세미나자료집 Vol.2008 No.9

전국의 수련 병원에서 사용하고 있는 한국어 단음절어음표의실태 및 어음 빈도 분석

변성완,정성민,김한수,고영민 대한이비인후과학회 2005 대한이비인후과학회지 두경부외과학 Vol.48 No.9

Background and Objectives:Although several Korean PB (phonetically balanced) word lists were proposed by many investigators, there is not yet a standard PB word list established in Korea. This study aims to study the actual condition of Korean PB word lists, to investigate the frequencies of Korean phonemes and to delineate the commonly used monosyllabic words among them. Materials and Method:The study materials were collected from 80 training hospitals in Korea. The frequencies of the initial consonants, vowels and final consonants in the collected lists were calculated with a computer program. Common monosyllabic words were summarized in a table according to their incidences in the lists. Results:Thirteen lists were used in 80 training hospitals. Hahm's list was most commonly used. Most lists showed a similar trend in the phoneme frequencies. The most common monosyllabic words were /gang/, /nun/, and /don/. Conclusion:These results might be valuable information for the production of a new standard Korean PB word list.

한국어의 음절빈도와 단음절 어음표의 음절분포

변성완 대한이비인후과학회 2003 대한이비인후과학회지 두경부외과학 Vol.46 No.9

Background and Objectives:There can be 3,192 sylables in Korean language but the frequencies of each sylables are variable. This study was aimed to investigate the frequencies of each Korean sylable in the everyday dialogue and to compare the result with the existing Korean phoneticaly balanced (PB) word list, which can provide the basic data for the Materials and Method:Using 33 materials (total 537,245 syllables) colected from TV drama (MBC Best Theater), the author calculated the frequencies of each Korean syllables composed of initial consonant and vowel and compared with existing PB word list by computer program. Results:Each sylable appeared in the diferent frequency pattern. The 138 of 399 syllables represented the 95% of everyday dialogue. Conclusion:This study showed that established PB word list was made relatively well but needs somewhat modification to reflect the actual frequencies of syllable in colloquialism. (Korean J Otolaryngol 2003 ;46 :737-41)

이비인후과 영역에서 Critical Pathway의 적용

변성완 대한이비인후과학회 2002 대한이비인후과학회지 두경부외과학 Vol.45 No.5

두경부편평상피암 연구의 3차원적 In Vitro 실험 모델 확립 : Spheroid 모델과 Raft 배양모델 Spheroid Model and Raft Culture Model

변성완,김춘동 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.1

Objectives : To establish new in vitro model systems that better reflect in vivo condition, multicellular tumor spheroids(MTS) and raft culture were developed using cell lines of squamous cell carcinoma(SCCHN) of the head and neck in these 3-dimensional systems. Materials and Methods : Four SCCHN cell lines were used for MTS and raft culture. Results : All cell lines formed MTS, but only Tu-138 showed a good stratification at the airliquid interface in the raft culture system. Conclusion : MTS and raft culture system were established successfully from the SCCHN cell lines.