추나치료를 병행한 돌출형 요추추간판탈출증 환자의 영상의학적 변화 1례

정벌 ( Bul Chung ),정석희 ( Seok Hee Chung ),이종수 ( Jong Soo Lee ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.3

Objectives : There are many studies on the resorption of extruded lumbar intervertebral disc herniation by MRI follow-up case study but few are about protrusion. So the purpose of this study is to know the difference of MRI scan on protrusion type after Chuna theraphy. Methods : The first MRI examination was performed at the first visit suffering from LBP and radiculopathy, and the second performed after treatment. The first image was compared with second one. Results & Conclusions : The second scan shows clearly disc resorption of L4-5 level compared with previous scan and clinical symptom assessed by VAS was also reduced after Chuna theraphy.

직업 유형에 따른 척추질환 유병률 조사

정벌 ( Beoul Jeong ),신동재 ( Dong Jae Shin ) 한방재활의학과학회 2010 한방재활의학과학회지 Vol.20 No.4

Objectives :Recently work-related musculoskeletal disorders have increased in various workplaces and many reports have been confirming this, but a comparative study on incidence of spinal disease by occupation has not been established yet. So this study was designed to clarify the distinction on incidence of spinal disease between white and blue collar workers. Methods :The subjects who visited with spinal disease to Ja-Seng oriental hospital from January to April in 2010 were selected and divided into white collar workers(n=844) and blue collar workers(n=333). We counted the number of patients with each spinal disease in both groups and carried out comparative analysis in five items(herniated nucleus pulposus(HNP), stenosis, spondylosis, sprain, etc). All data were analyzed by chi-square test. Results and Conclusions :White collar workers had higher incidence in HNP(p=0.030), sprain(p=0.016), etc(p=0.035) than blue collar workers, while blue collar workers had higher incidence in stenosis(p=0.002). But we think that the confidence is low in stenosis because the number of cases are very small. There were no significance between two groups with spondylosis.

성향정기산(星香正氣散)이 중대뇌동맥폐쇄 흰쥐의 Bax 및 Bcl-2 발현에 미치는 영향

정벌 ( Beoul Jeong ),이종수 ( Jong Soo Lee ) 한방재활의학과학회 2008 한방재활의학과학회지 Vol.18 No.2

Objectives : Sunghyangjungki-san(Xingxiangzhengqi-san) is a herb decoction prescribed frequently for stroke patients. The present study investigated neuroprotective effects of Sunghyangjungki-san(Xingxiangzhengqi-san) against the ischemic damage of the rat brain. Neuronal cell death under the cerebral ischemia is distinguished with the delayed cell death through apoptosis. Consequently, the effects of Sunghyangjungki-san(Xingxiangzhengqi-san) was evaluated with Bax and Bcl-2 expressions as apoptosis related factors in the brain tissues. Methods : The ischemic damage was induced by the middle cerebral artery occlusion(MCAO) method in Sprague-Dawley rats. Water extract of Sunghyangjungki-san(Xingxiangzhengqi-san) was treated for 5 days after the MCAO. Neurological scores and infarct size with TTC were measured. Bax and Bcl-2 expressions in the brain tissues were observed with immunohistochemistry. Results : Sunghyangjungki-san(Xingxiangzhengqi-san) treatment improved neurological score significantly at 5 days after the MCAO. Sunghyangjungki-san (Xingxiangzhengqi-san) treatment decreased infarct size by the MCAO, but it was not significant statistically. Sunghyangjungki-san(Xingxiangzhengqi-san) treatment attenuated Bax positive neurons significantly in the cerebral penumbra and the caudate putamen. Bcl-2 positive neurons were increased, but not significant. Sunghyangjungki-san(Xingxiangzhengqi-san) treatment increased Bcl-2/Bax expression ratios significantly in the cerebral penumbra and the caudate putamen. Conclusions : These results suggest that Sunghyangjungki-san(Xingxiangzhengqi-san) has a neuroprotective effect on the stroke with modulation of apoptosis related factors.

Ginsenoside Rg3이 흰쥐 척수압박손상의 초기 염증반응에 미치는 영향

정벌 ( Beoul Jeong ),이종수 ( Jong Soo Lee ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.2

Objectives : In present study, we investigated the effects of ginsenoside Rg3 on early-stage inflammatory response in spinal cord compression of rodents. Methods : Spinal cord injury(SCI) was induced by a vascular clip method(30 g, 5 min) on the spinal cord of mice. Rg3 was treated orally at 1 hour prior to the SCI induction. Messenger ribonucleic acid(mRNA) expression of tumor necrosis factor-α(TNF-α), interleukin-1β(IL-1β), interleukin-6(IL-6) and cyclooxygenase-2(COX-2) was measured by the real-time polymerase chain reaction(RT-PCR). Microglia in the spinal cord tissue, neurophils and COX-2 in the peri-lesion and inducible nitric oxide synthase(iNOS) expression in the ventral horn of SCI induced rats were measured by immunohistochemical stain. Results : 1. Rg3 significantly reduced the mRNA expression of TNF-α, IL-1β, and COX-2 in the spinal cord tissue compared with SCI group(p<0.05, p<0.01). 2. Rg3 significantly reduced the total number of activated microglia and proportion of phagocytic form in the total activated microglia compared with SCI group(p<0.05, p<0.01). 3. Rg3 significantly reduced myeloperoxidase(MPO) positive neurophil in the peri-lesion compared with SCI group(p<0.05). 4. Rg3 reduced the COX-2 expression in the tissue and motor neurons compared with SCI group. 5. Rg3 significantly reduced iNOS positive motor neurons in the ventral horn compared with SCI group(p<0.01). Conclusions : In conclusion, we demonstrated at first that treatment of ginsenoside Rg3 could reduce significantly the levels of inflammatory mediators in a spinal cord compression model of rodents. Therefore, these results suggested that ginsenoside Rg3 may be a useful antimiflamatory therapeutic candidate for SCI.

만성 요통환자에서 성별에 따른 고관절 내회전 각도의 비교

이재영,한상엽,남항우,정벌,이차로,한상욱,Lee, Jae-Young,Han, Sang-Yup,Nam, Hang-Woo,Chung, Bul,Lee, Cha-Ro,Han, Sang-Wook 척추신경추나의학회 2010 척추신경추나의학회지 Vol.5 No.2

Objectives : This study is planned to classify different biomechanics of men and women, from the comparison of normal range and hip internal rotation angle in chronic low back pain patients. Methods : We measured the hip internal rotation angle of the 30 men and 30 women patients with low back pain that has been over 3 months in BuCheon Jaseng Hospital of Oriental medicine. We set 35-45 degrees as normal range, and found the patients with exceeding normal range, the patients with normal range, and the patients with under normal range. Results : Men appeared to have less hip internal rotation angle than women. Especially, the men's left hip internal rotation angle was less than normal range. On the other hand, women's right hip internal rotation angle was often larger than normal range which was stastically significant. Conclusions : Contraction of hip external rotation muscle including gluteus maxius muscle and piriformis muscle in men, or relaxation of posterior gluteus medius, gluteus maxius and piriformis muscle with contraction of tensor fasciae latae, a part of hip internal rotation muscle, in women seems to be the basis for biomechanics of chronic low back pain.

급성기 외상성 슬관절 반월상 연골판 손상 환자에 대한 기존 한방치료에 관절강내 봉약침 시술을 추가 시행한 치험 1례

이재훈,김준수,정영훈,정벌,이차로,Lee, Jae-Hoon,Kim, Jun-Soo,Jeong, Young-Hoon,Jeong, Byul,Lee, Cha-Ro 대한약침학회 2010 Journal of pharmacopuncture Vol.13 No.4

외상성 급성기 슬관절 반월상 연골판 손상으로 인하여 통증 및 보행장애를 호소하는 환자에 대하여 관절강내 봉약침을 시술하였으며 그 결과 통증의 감소 및 보행시간의 증가와 WOMAC Index score의 감소를 확인하였다. 향후 슬관절 반월상 연골판 손상환자에 대한 봉약침 시술의 효과에 대한 적용 및 연구가 더욱 필요할 것으로 생각된다. This case was report of intra-articular bee venom pharmacopuncture injection on the patient with Acute Traumatic Partial tear of meniscus. We used intra-articular bee venom pharmacopuncture injection to Acute Traumatic Partial tear of meniscus diagnosed by symptoms and MR imaging. Be under treatment if necessary we prescribed herbal medication and physiotherapy. The state of patient was measured by Visual Analog Scale(VAS) and Walking time and Western Ontario and McMaster Universities(WOMAC) Index score. After several times of treatments, noticeable reduction of pain was measured and increased time of walking on floor and decreased WOMAC score. This results suggest that intra-articular bee venom pharmacopuncture injection are effective to treatments of Acute Traumatic Partial tear of meniscus.

Muscle Energy Techniques 및 한의학적 치료를 이용한 후천성 회전형 사경의 치험 1례

김진수,정윤규,김정원,신동재,남항우,정벌,Kim, Jin-Soo,Jung, Yoon-Gyoo,Kim, Jung-Won,Shin, Dong-Jae,Nam, Hang-Woo,Chung, Bul 척추신경추나의학회 2011 척추신경추나의학회지 Vol.6 No.1

후천성 회전형 사경으로 입원 치료한 환자 1례에 대하여 MET 기법을 위주로 한 한의학적 치료가 주소 증상에 유효한 효과가 있음을 확인하였다. 이에 저자는 본 증례를 보고하는 바이다. Objectives : The purpose of this study is to investigate the clinical application of Muscle Energy Techniques(MET) and Oriental Medicine to a patient who had Acquired Rotating Torticollis. Methods : A patient diagnosed as acquired torticollis was hospitalized at Buchun Jaseng hospital of Oriental Medicine for 28 days and she was treated by MET, herbal medicine and acupuncture. To measure the outcome of the patient's improvement, we observed Numerical Rating Scale(NRS), Neck Disablility Index(NDI), Tsui's Scale and the X-rays of Whole spine. Results : After being treated by MET and Oriental Medicine, the patient's pain was reduced and the head rotating was significantly improved. The improvement of patient in the NRS, NDI, Tsui's Scale was detected and the X-ray of Whole spine became normal. Conclusions : As seen in this case, complexed therapy with MET and Oriental Medicine is effective treating method to control pain and head rotating for patients with acquired rotating torticollis.

관상동맥질환자에서 식이, 생활양식 요인과 혈청 항산화영양소 상태 및 혈청 지질에 관한 연구

최영선,박의현,송경은,이정벌,서정미,이난희,조성희 한국지질동맥경화학회 1999 韓國脂質學會誌 Vol.9 No.2