소아 갑상선 수질암종 1례

정광윤,박찬,이재용,최종욱,유홍균,Jung, Kwang-Yoon,Park, Chan,Lee, Jae-Yong,Choi, Jong-Ouck,Yoo, Hong-Kyun 대한기관식도과학회 1996 大韓氣管食道科學會誌 Vol.2 No.2

저자들은 좌측 전경부 종물을 주소로 내원한 9세 여아에서 발생한 갑상선수질암종을 갑상선 전절제술 및 술후 방사성요드로 치료한 경험을 보고하는 바이다. Medullary thyroid carcinoma constitutes about 5-10% of all thyroid malignancies, but rare in children. It has frequent association with multiple endocrine neoplasia(MEN) and frequent familial occurrence. They are derived from parafollicular cells of thyroid glands and produce calcitonin. They are capable of local invasion, spread to regional lymph nodes, or distant metastases. Histopathologically, the lesions are characterized by sheets of non-follicular cells surrounded by deposits of hyaline amyloid. Aggressive surgical intervention is recommended due to the propensity of medullary thyroid carcinoma for local microvascular invasion, late recurrence and metastasis. A total thyroidectomy is generally recommended because of the high incidence of bilaterality. Recently, authors experienced a case of medullary carcinoma in child. We report this case with review of the literatures.

다형선종 수술 후 발생한 이하선 점액표피양암종

정광윤(Kwang-Yoon Jung),채양석(Yang-Seok Chae),백승국(Seung-Kuk Baek),박민우(Min-Woo Park),유준혁(Joon-Hyuk Yoo) 대한두경부종양학회 2012 대한두경부 종양학회지 Vol.28 No.1

Mucoepidermoid carcinoma is most frequent malignant tumor of parotid gland. However, mucoepidermoid carcinoma arising from pleomorphic adenoma has been disputed and rarely reported. 54-year-old woman with pleomorphic adenoma underwent superficial parotidectomy. And 15 years later, she diagnosed mucoepider-moid carcinoma at the same side. We report the case with a review of literature.

초기 성문암종에서 레이저를 이용한 성대절제술의 효과

유홍균(Hong Kyun Yoo),최건(Geon Choi),정광윤(Kwang Yoon Jung),민헌기(Hun Ki Min),박정수(Jung Soo Park),최종욱(Jong Ouck Choi) 대한두경부종양학회 1996 대한두경부 종양학회지 Vol.12 No.2

이상의 성적에서 레이저 성대 절제술은 초기 성문암종에 대한 일차 치료법으로 유용하다고 생각되었으며, 일차 절제가 가장 중요하고 그후 성대를 포함한 전체 후두점막에 대하여 주기적으로 현수후두경하에 수술현미경을 이용한 추적관찰과 원격전이 및 이차암의 발생 유무에 대하여 적극적인 추적검사가 필요할 것으로 사료된다. Early detection of glottic cancer, facilitated by rigid telescopes or flexible fiberoptic laryngoscope in addition to sparse true vocal cord lymphatics, makes this a highly curable tumor in its early stage. Early glottic cancer has a high cure rate with only radiotherapy or conservative surgery. However complications such as mucositis with radiotherapy and voice complications with conservative surgery has raised recent interest in endolaryngeal laser cordectomy. Laser cordectomy can preserve phonatory function and avoid the complications such as mucositis of radiotherapy. To determine the effectiveness of laser cordectomy, the authors made a two year retrospective study of 23 early glottic cancer cases. Fourteen cases(60.9%) who underwent 1 to 3 endoscopic laser cordectomy with KTP-532 laser were cured with this procedure alone. Seven cases needed an additional radiotherapy and three cases needed therapy with salvage operation. We conclude that the endoscopic laser surgery is a good strategy for the properly selected glottic cancer.

후두아밀로이드증 1례

박호정,유강목,송종석,최건,정광윤,최종욱,Park, Ho-Jeong,Yoo, Kang-Mok,Song, Jong-Seok,Choi, G대n,Jung, Kwang-Yoon,Choi, Jong-Ouck 대한기관식도과학회 1996 大韓氣管食道科學會誌 Vol.2 No.1

Laryngeal amyloidosis is a rare benign disease. It is characterized by extracellular deposition of homogeneous and eosinophilic protein material in the form of fibrils. Diagnosis of this disease is made by histologic examination of involved tissue. It is ususlly primary or localized but rarely associated with a systemic or generalized disease. We present a case of primary laryngeal amyloidosis that was treated with KTP 532 laser vaporization.

후두전적출술 후 장기적인 삶의 질에 대한 평가

권순영(Soon Young Kwon),유홍균(Hong Kyun Yoo),정광윤(Kwang Yoon Jung),최정철(Jung Chui Choi),한승훈(Seung Hoon Han),최종욱(Jong Ouck Choi) 대한두경부종양학회 2000 대한두경부 종양학회지 Vol.16 No.2

Objectives: Despite various attempts to preserve the normal voice in advanced laryngeal cancer, it is inevitable for many advanced laryngeal cancer patients to undergo total laryngectomy and thus making a trade off between quality and quantity of life. Laryngectomees are faced with voice loss, change in physical appearance and health deterioration which hinder their efforts to rehabilitate back into their family and employment leading to poor quality of life. The objectives of this study were to evaluate the quality of life in long term surviving laryngectomees to, define the factors which are most important in determining their present quality of life and to propose a theoretical model for quality of life after laryngectomy in Korea. Materials and Methods: From 1986 to 1995, 120 laryngectomees with no evidence of disease were followed up for at least 3years were evaluated. Each of 15 quality of life domains with a total of ten points were given for a quality of life score. Results: There was no significant difference in the physical-mental adaptation index such as general health and mental health between the laryngectomees and control group(p>0.05). However, social adaptation index such as social activity, occupational status and economic status for laryngectomees were significantly lower with 2.3, 3.5, and 4.4 points compared to control group with 8.5, 7.6, and 7.1 points respectively(p<0.05). Conclusion : Vocational and social rehabilitation should be emphasized with highest priority for improving their economic status and thus improving their quality of life.

성대용종환자에서 후두미세수술시에 수술부위에 Triamcinolone 국소주입이 음성에 미치는 영향에 대한 연구

유준,오경호,윤희철,이도영,우정수,백승국,정광윤,권순영,Yoo, Jun,Oh, Kyung Ho,Yoon, Hee Chul,Lee, Doh Young,Woo, Jeung soo,Baek, Seung Kuk,Jung, Kwang Yoon,Kwon, Soon Young 대한후두음성언어의학회 2015 대한후두음성언어의학회지 Vol.26 No.2

Background and Objective : Laryngeal microscopic surgery (LMS) is popular method to treat for vocal polyp. There is not always the improvement of the voice after operation. Many methods have been developed for better outcome of the surgery. The purpose of this study is to investigate the effect of the triamcinolone injection at vocal cord during LMS. Materials and Methods : The medical records of 28 patients, received LMS under diagnosis of vocal polyp, were retrospectively reviewed. The patients were divided into two groups depending on whether triamcinolone injected or not (case group : Triamcinolone-injected group, control group : Triamcinolone-not injected group). The quality of voice was evaluated by GRBAS scale, fundamental frequency (Fo), jitter, shimmer and NHR (Noise to harmonic ratio) at previous operation, 4 weeks after operation, 8 weeks after operation. Each voice analysis factor was compared between case group and control group by Independent t-test. Results : The mean differences of each voice analysis factor. The mean difference of Jitter, Shimmer, NHR in case group were lower than in control group, and mean difference of GRBAS scale in case group were higher than in control group. These differences were not significant (p>0.05). Conclusion : Though there was a tendency of better voice outcome in patients of triamcinolone-injection, it may not be concluded that the triamcinolone injection is helpful for better voice outcome in surgery of vocal polyp due to statistical insignificance.

부갑상선 종양의 치험 6례

조우성(Woo-Sung Cho),김우주(Woo-Joo Kim),유익원(Ik-One Yoo),황호연(Ho-Yeon Hwang),백승국(Seung-Kuk Baek),우정수(Jeong-Soo Woo),권순영(Soon-Young Kwon),정광윤(Kwang-Yoon Jung) 대한두경부종양학회 2007 대한두경부 종양학회지 Vol.23 No.2

Parathyroid gland tumor is an uncommon disease. The symptoms of parathyroid gland tumor appear in various features such as general weakness, renal stones, bone diseases and malignancies in some cases. We summarized the clinical features of 6 cases of parathyroid gland tumors with literatures.

소타액선 종양에 관한 임상적 고찰

이종수(Chong Soo Lee),최종욱(Jong Ouck Choi),이승호(Seung Ho Lee),정광윤(Kwang Yoo Jung),이남준(Nam Joon Lee) 대한두경부종양학회 1994 대한두경부 종양학회지 Vol.10 No.1

최근 7년간 저자들이 치험한 소타액선 종양 26례에 대하여 임상양상과 치료 결과를 분석하여 다음과 같은 성적을 얻었다. 1) 발생부위를 구개 10례 (38.5%), 비강 및 부비동 8례 (30.8%), 설근부 2례 (7.7%), 협부 점막 2례 (7.7%), 구순 1례(3.8%), 후두개곡 1례(3.8%), 구강저 1례(3.8%), 비인강 1례(3.8%)이었다. 2) 병리조직학적 소견은 양성 종양 10례, 악성종양 16례이었으며, 양성 종양은 전례가 다형성선종이었으며, 구개에서 6례로 가장 많았고, 악성종양은 비강 및 부비동 5례로 가장 많았으며, 선양낭성암종 9례, 악성혼합종 2례, 점액표피암종 2례, 다형성선암종 2례, 상피근상피성암 1례이었다. 악성화율은 61.5%이었다. 3) 치료는 양성 종양은 모두 적출술을 시행하였고 악성 종양은 광범위 적출술 4례(25.0%), 수술 및 방사선요법의 병합요법 9례(45.2%), 항암화학요법 및 방사선요법의 병합요법 1례(5.25%), 방사선 요법 2례(12.3%)등을 시행하였다. 4) 악성 종양에 대한 치료 결과는 근치적 치료를 시행한 8례에서는 무병생존 6례, 유병생존 1례, 유병사망 1례를 보였으며, 고식적 치료를 시행한 6례에서는 유병생존 2례, 유병사망 4례를 보였다. 이상의 성적에서 소타액선 종양은 대타액선 종양에 비하여 악성화 비율이 높고 선양낭성암종의 발생 빈도가 높아 그 침범 부위를 정확히 파악하는 것이 치료에 많은 도움을 줄 수 있으며, 고식적 치료의 범위를 확대하여 보다 적극적인 치료가 필요할 것으로 생각된다. Minor salivary gland tumors vary in their primary sites, histopathology and bilogical behavior. Therefore various factors are considered in selecting the treatment modality and predicting the prognosis. The prognosis of milignant tumors of minor salivary glands are worse than that of such lesions of major salivary glands. Authors experienced 26 cases of minor salivary gland tumors(10 benign tumors and 16 malignant tumors) during the past 7 years and analyzed their clinical characteristics. 1) The palate was the most common site of origin of minor salivary gland tumors (38.5%). 2) The most common benign tumor was pleomorphic adenoma and majority of them occur red in the palate(60.0%) and the remaining occured in the nasal cavity or the paranasal sinuses (30.0%), and the lip ( 10.0%). 3) In the case of malignant tumors the most frequent sites were the nasal cavity or the paranasal sinuses (31.3%) with the following histopathologic frequencies: adenoid cystic carcinoma(56.3%), malignant pleomorphic adenoma(12.5%), mucoepidermoid carcinoma(12.5%), polymorphic adenocarcinoma (12.5%), epthelial-myoepithelial carcinoma (6.25%). 4) Minor salivary gland tumors have high probability of malignancy and tumor extension is important to their treatment.

악성신경초종 2례

김찬우(Chan Woo Kim),최종욱(Jong Ouck Choi),정광윤(Kwang Yun Jung),유홍균(Hong Kyun Yoo) 대한두경부종양학회 1992 대한두경부 종양학회지 Vol.8 No.1

Malignant schwannoma is a rare tumor arising from the schwann sheath of the nerve fibers. It spreads early to reginal node and metastasis to the lung. Radical surgery have performed for treatment of choice but combined modalities such as radiotherapy or adjuvant chemotherapy have been recommanded recently. The authors experienced two cases of malignant schwannoma originating from the ethmoid sinus and ventricular fold of larynx. and we report these cases briefly.

보존적 수술을 시행받은 후두암 환자의 치료성적

이순영(Soon Young Lee),최종욱(Jong Ouck Choi),정광윤(Kwang Yoon Jung),유홍균(Hong Kyun Yoo) 대한두경부종양학회 1991 대한두경부 종양학회지 Vol.7 No.1

The purpose of conservation surgery is complete eradication of the lesion with maximal maintenance of the proper function of the larynx. But the re are various methods of conservation surgery for the laryngeal cancer because of the unique embriological and anatomical characteristics of the larynx, which is the narrowest portion of the upper airway. The authors experienced 24 cases of conservation surgery for laryngeal cancer(7 in supraglottie cancer, 13 in glottic cancer, 4 in transglottic cancer) during recent 5 years and performed retrospective analysis of the cases. The result shows 91.6% of overall 3 years survival rate(87.5% of disease free 3 year survival rate). The authors concluded that conservation surgery for the laryngeal cancer preserve the function of larynx as possible and high cure rates were achieved by postoperative radiation therapy for the incomplete resection margin.