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궤양성 대장염에서 나타난 폐쇄성 세기관지염 기질화 폐렴
이현정 ( Hyun Jung Lee ),박병훈 ( Byung Hoon Park ),손지영 ( Ji Young Son ),정지예 ( Ji Ye Jung ),황세나 ( Se Na Hwang ),전영은 ( Young Eun Chon ),김은영 ( Eun Young Kim ),임주은 ( Ju Eun Lim ),이경종 ( Kyung Jong Lee ),윤여운 ( Y 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.68 No.3
The ulcerative colitis is a chronic inflammatory bowel disease with an unknown etiology. The major symptoms of ulcerative colitis are diarrhea, abdominal pain and hematochezia. However, arthritis, skin disorders, hepatobiliary inflammation and uveitis are occasionally recognized as systemic complications. Although there are few reports of coexistent pulmonary and inflammatory bowel disease, the lung is not generally considered to be a target organ in ulcerative colitis. We report a patient with ulcerative colitis-related bronchilolitis obliterans organizing pneumonia confirmed by video-assisted thoracoscopic surgery, who responded to corticosteroid therapy.
정은석 ( Eun Suk Jung ),천재희 ( Jae Hee Cheon ),이경주 ( Kyong Joo Lee ),이현정 ( Hyun Jung Lee ),장희원 ( Hui Won Jang ),전영은 ( Young Eun Chon ),정규식 ( Kyu Sik Jung ),장선정 ( Seonjung Chang ),홍성필 ( Sung Pil Hong ),김태일 대한장연구학회 2010 Intestinal Research Vol.8 No.2
Colitis Cystica Profunda (CCP) is an uncommon and benign disease entity characterized by mucoid cysts located in the submucosal layer of the colon. It can mimic cystic submucosal tumors or mucinous adenocarcinoma and is usually located in the rectum. CCP is found in the ascending colon less frequently. CCP manifesting as multiple cystic tumors, similar to pneumatosis cystoides intestinalis, has not yet been reported. Recently, a case of CCP mimicking pneumatosis cystoides intestinalis in the ascending colon was treated. Here this case is reported and the literature reviewed. (Intest Res 2010;8:187-190)
간외 전이를 동반한 진행성 간세포암에서 자가유래 자연살해세포와 면역관문 억제제 병합치료 1예
우아라 ( Ara Woo ),김은주 ( Eun Ju Kim ),신선영 ( Sun Young Shin ),전홍재 ( Hong Jae Jeon ),박하나 ( Hana Park ),전영은 ( Young Eun Chon ),이윤빈 ( Yun Bin Lee ),황성규 ( Seong Gyu Hwang ),임규성 ( Kyu Sung Rim ),이주호 ( Joo Ho L 대한간암학회 2018 대한간암학회지 Vol.18 No.1
Hepatocellular carcinoma (HCC) has extremely poor prognosis. Immunotherapy has emerged as a new treatment for a number of cancers. Adoptive immunotherapy is one of the important cancer immunotherapy, which relies on the various lymphocytes including cytotoxic T lymphocytes, natural killer (NK) and cytokine induced killer cells. Also, there has been advance in techniques of NK cell activation to more effectively kill the cancer cells. Of note, recently the blocking antibodies targeting programmed cell death protein 1 (PD-1) have shown promising results in diverse cancers including HCC. We report our recent experience of a patient accompanying advanced HCC with extrahepatic metastases. Disease progression had occurred after sorafenib administration, while the patient showed local tumor control and tumor marker decrease by NK cell immunotherapy combined with PD-1 inhibitor therapy. Though, there was no definite survival advantage due to impaired liver function, which might be caused by treatment related toxicities as well as cancer progression. (J Liver Cancer 2018;18:67-74)
TACE 및 Adjuvant Brivanib 치료로 완치된 뒤 21개월 후 재발성 간암으로 이식한 증례
이상헌 ( Sangheun Lee ),김미나 ( Mi Na Kim ),전영은 ( Young Eun Chon ),김범경 ( Beom Kyung Kim ),김승업 ( Seung Up Kim ),박준용 ( Jun Yong Park ),김도영 ( Do Young Kim ),안상훈 ( Sang Hoon Ahn ),전재윤 ( Chae Yoon Chon ),한광협 ( 대한간암학회 2013 대한간암학회지 Vol.13 No.1
Hepatocelluar carcinoma (HCC) is the most common primary liver cancer in the world and the most prevalent cancer among patients liver cirrhosis. The management of HCC depends on tumor stage and the degree of liver dysfunction. Patients with intermediate-stage HCC are ineligible for surgical or local ablative treatments. Current treatment guidelines recommend trans-arterial chemoembolization (TACE) for intermediate stage of HCC. However, tumor recurrence after TACE is universal and the survival benefit is relatively small. Hence, new strategies are needed to improve the outcome of HCC patients undergoing TACE. Recently, the combination of target agents with TACE has shown promising overall survival in advanced HCC. It is necessary to investigate new treat strategy how to increase treatment outcome of advanced HCC by new treat strategy.
사례보고 : 간문맥혈전증을 동반한 특발성 문맥고혈압 환자에서 Protein C, Protein S 결핍 1예
황세나 ( Se Na Hwang ),김도영 ( Do Young Kim ),김민주 ( Min Ju Kim ),전영은 ( Young Eun Chon ),이현정 ( Hyun Jung Lee ),박영년 ( Young Nyun Park ),박준용 ( Jun Yong Park ),안상훈 ( Sang Hoon Ahn ),한광협 ( Kwang Hyub Han ),전재윤 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.2
Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal portal hypertension. Among various hepatoportal disorders, noncirrhotic portal hypertension conditions such as idiopathic portal hypertension (IPH) are considered to have a close relation with PVT. PVT is known to have several predisposing conditions, including infection, malignancies, and coagulation disorders. There is growing interest and recognition that deficiencies in proteins C and S are associated with a hypercoagulable state. These deficiencies are regarded as key factors of systemic hypercoagulability and recurrent venous thromboembolism. We report the case of a 19-year-old male diagnosed as IPH with PVT and combined deficiencies in proteins C and S.
간세포암종의 경간동맥화학색전술 시행 후 발생한 괴사성 췌장염 1예
김미나 ( Mi Na Kim ),조중현 ( Jung Hyun Cho ),전영은 ( Young Eun Chon ),김범경 ( Beom Kyung Kim ),김승업 ( Seung Up Kim ),박준용 ( Jun Yong Park ),김도영 ( Do Young Kim ),안상훈 ( Sang Hoon Ahn ),한광협 ( Kwang Hyub Han ),전재윤 ( 대한간암학회 2012 대한간암학회지 Vol.12 No.2
Acute pancreatitis is a rare but severe postprocedural complication after transcatheter arterial chemoembolization (TACE) of hepatocellular carcinoma with an incidence of 1.7-4%. The proposed mechanism of this complication is inadvertent embolization through collateral vessels or regurgitation of chemotherapeutic agents to the arteries of other organs. Here, we present a fatal necrotizing pancreatitis case which developed 10 days after TACE, caused by the regurgitation of the chemotherapeutic agents to the pancreas during the procedure. The patient recovered with conservative care at first, but after suffering from several times of recurrent pancreatitis, he died of peritoneal septic shock 5 months after the initial pancreatitis attack.