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니켈크롬강과 ZrO2 접합체의 접합강도에 미치는 ZrO2 안정화제의 영향
유연철,이용철,장병록 대한금속재료학회(대한금속학회) 1990 대한금속·재료학회지 Vol.28 No.10
Effects of ZrO₂ stabilizers such as 3㏖% Y₂O₃, 8㏖% Y₂O₃, and 9㏖% MgO on the joining phenomena of Ni-Cr steel/Al/ZrO₂ joints have been examined by the concept of solid state diffusion bonding. Irrespective of stahilizers used, the Al/ZrO₂ joint whose reaction layer could not be detected showed a good contact while the reaction layer of the Ni-Cr steel/Al was the diffusion layer of Al and Fe. The joint shear strength of this system did not show any distinct differences even though ZrO₂ stabilizers are varying. The maximun shear strength was 27 ㎫ under a pressure of 100 ㎫, temperature of 635℃, and the time of 120min. The residual stress resulting from the thermal expansion mismatch between ZrO₂ and A1 was different depending on the A1 layer depth sites. It was shown that compressive residual stress could be found at the Al/ZrO₂ interface while tensile residual stress at the NI-Cr steel/Al interface.
루푸스 신염 환자에서 발생한 폐 Nocardia 감염증
장선주 ( Sun Joo Chang ),이강녕 ( Kang Nyoung Lee ),성윤경 ( Yoon Kyoung Sung ),이혜순 ( Hye Soon Lee ),엄완식 ( Wan Sik Uhm ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),배현주 ( Hyun Joo Pai ),배상철 ( Sang Cheol Bae ),전석철 대한류마티스학회 2005 대한류마티스학회지 Vol.12 No.1
Nocardiosis is uncommon in healthy people, but occurs as an opportunistic infection in patients with connective tissue disease, solid organ transplantation, lung disease, malignancies, and the acquired immune deficiency syndrome (AIDS). Nocardia is a gram positive, variably acid-fast aerobic bacterium of the family Nocardiaceae characterized by branching and filamentous growth, with distinctive aerial hyphae. In systemic lupus erythematosus (SLE) patients, immunosuppressiion with cytotoxic drugs or corticosteroids, proteinuria, renal insufficiency, and active SLE itself are known as risk factors for serious bacterial infections and opportunistic infections. We report a case of pulmonary Nocardiosis in patient with lupus nephritis treated with cyclophosphamide and high dose corticosteroid.
장예진,지미란,전미향,김점순,김경운,한덕우,정학재,양병철,류재규,박진기,김태완,변승준 韓國家禽學會 2012 韓國家禽學會誌 Vol.39 No.3
본 연구는 형질전환 닭에서 주입한 외래 유전자의 세대간 전이와 발현 양상을 조사하고자 하였다. 외래 유전자 전이 양상 조사는 제3세대(G2) GFP 형질전환 수탉을 최초 부계로 사용하여 최종적으로 제9세대(G8) 형질전환 닭을 연속적으로 생산하면서 GFP 유전자 전이 양상을 조사하였다. 형질 전환 병아리 유전 분석은 자외선 램프 아래에서 부화한 병아리들의 날개, 부리와 다리에서 녹색형광단백질을 발현하는 병아리들만을 형질전환으로 선발하였다. 형질전환 닭에서 외래 유전자 전이율은 대략 38~58%이었다. 이는 유전자 전이가 멘델의 유전 법칙을 따르고 있음을 보여주고 있다. 연구결과는 GFP 유전자가 유전자 침묵 없이 멘델의 유전 법칙에 따라 다음 세대로 계속 전이와 발현된다는 것을 보여 주고 있다. This study was performed to analyze the generational transmission and the expression of the foreign gene in the GFP transgenic chickens. The transmission rate and the expression of the GFP gene was investigated from the GFP transgenic rooster (G2) as the first founder to the ninth (G8). Analysis of GFP expression in hatched chickens was used the UV lamp. When GFP was expressed in the wings, bill and legs of a chick, the bird only was selected as a transgenic chick. The average transmission rate of the overall transgenic was 38~58%. These results showed that the transmission of the GFP gene in the transgenic chickens in accordance with the laws of Mendel's continues to the next generation without gene silencing.