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- 저자 : 임용철 ( Yong Cheol Lim ) (검색결과 2 건)
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임상 : 성장 호르몬 분비 뇌하수체 선종 환자의 수술적 치료 결과
목영준 ( Young Jun Mok ),임용철 ( Yong Cheol Lim ),신용삼 ( Yong Sam Shin ),윤수한 ( Soo Han Yoon ),조기홍 ( Ki Hong Cho ),조경기 ( Kyung Gi Cho ) 대한뇌종양학회 2007 대한뇌종양학회지 Vol.6 No.2
Objective:Control of growth hormone(GH) and insulin-like growth factor-I(IGF-I) levels are important in patients with GH-secreting adenomas because they are indicators of biochemical control of GH-secreting adenomas characterized by serious cardiovascular and metabolic complications. Surgical treatment is usually considered as the first choice of treatment in GH-secreting adenomas. In this study, we evaluated the efficacy and safety of surgical treatment with GHsecreting pituitary adenoma. Methods:We have reviewed medical records, radiologic findings, and endocrinologic evaluations of patients with GHsecreting pituitary adenoma who were treated by surgery between 1996 to 2004. Results:Twenty eight cases of GH-secreting pituitary adenoma(15 males and 13 females) have underwent surgery in our institute. The twenty eight cases included 22 patients with macroadenoma and 6 patients with microadenoma. Preoperative GH levels ranged between 1.77 and 82 μ/L(mean 20.7±14.3 ng/ml) and preoperative IGF-I levels ranged from 424 to 1710 ng/ml(mean 905.3±374.96 ng/ml). And the maximum diameter of tumors were between 4 mm and 70 mm. Twenty six patients were operated by transsphenoidal surgery and 2 patients underwent transcranial surgery. Gross total resection was achieved in 25 of the 28 cases. All patients` serum GH levels after oral glucose tolerance test(oGTT) decreased after surgery. Surgical cure after surgery(mean GH <2 μ/L and a nadir value after oGTT of <1 μ/L) was founded in 13 patients(8 of 22 macroadenoma and 5 of 6 microadenoma). No cases of mortality or major immediate postoperative complications were observed. Conclusion:Surgical treatment is safe and effective and we suggest the surgery could be a primary treatment not only for GH-secreting microadenoma but also for macroadenoma with cavernous sinus invasion.
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김유철,고광철,임용철,최규완,최병인 대한소화기내시경학회 1988 Clinical Endoscopy Vol.8 No.2
The purpose of this study is to review epidemiological and clinical characteristics of diverticular disease of the colan in Korea and to discuss the difference of the findings from those in other countries. Reviewing all thebarium enema films taken at the Seoul National University Hospital retrospectively for the last 8 years. that is, from January 1, 1980 to December 31, 1987, we observed the annual and overall incidence of the disease, the number and location of the diverticula, and the presenting symptoms of the cases. The results are summarized as follows: 1) Out of the patients examined, 237 cases had one or more diverticula in the colon, the overall incidence being 1.32%, 2) The annual incidence increased progressively for the last 8 years, from 0.25% in 1980 to 2.53% in 1987. 3) The mean age of the patients at the time of diagnosis was 51 years. The male to female ratio was 2.5. 4) The diverticula were located on the right side in 81.0% of the cases, on the left side in 10.6%, and on both sides in 8.4%. 5) In 82 cases (34.6%) single diverticulum was found, whereas 34 cases (14.3%) had more than 10 diverticula. 6) The most frequent symptoms for taking barium enema were abdominal discomfort and pain (34. 2%) and changes in bowel habits (33.8%}, whereas 45 casea (19.0%) had the examination just for a routine health check. In conclusiion, the diverticular disease of the colon is still uncommon in Korea as compared with in western countries, and the right colon type is far more freqtaent than the left colon type. However in recent years the incidence increases quite rapidly and the left colon type is getting more common.
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