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이정연 ( Jung Yeon Lee ),이시현 ( See Hyun Lee ),최연진 ( Yeon Jin Choi ),신미선 ( Mi Seon Shin ),안지영 ( Ji Young Ahn ),박미연 ( Mi Youn Park ) 大韓皮膚科學會 2009 大韓皮膚科學會誌 Vol.47 No.12
We report here on a 71-year-old female who had well-demarcated erythematous patches, along with some pearly papules, on the right cheek. Histopathological examination of the lesions revealed a basaloid cell mass, which appeared to be a superficial basal cell carcinoma, and a small keratin-filled cyst that appeared to be a milium. A part of the milium was surrounded by the basaloid cells of tumor islands and milia later developed on the lesion of basal cell carcinoma. We suggest that basal cell carcinoma may be one of the causes of secondary milia. (Korean J Dermatol 2009;47(12):1397∼1399)
이정연 ( Jung Yeon Lee ),김민수 ( Min Soo Kim ),이시현 ( See Hyun Lee ),김현수 ( Hyun Soo Kim ),안지영 ( Ji Young Ahn ),박미연 ( Mi Youn Park ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.1
Malignant syphilis (also known as lues maligna) is a rare dermatologic manifestation of syphilis and this is more commonly seen in patients with human immunodeficiency virus (HIV) infection. A 40-year-old man presented with general malaise and widespread cutaneous noduloulcerative lesions covered with lamellar crusts for 15 days. He had been diagnosed with HIV infection 6 years earlier, but had not regularly taken antiretroviral drugs. The syphilis serology showed a VDRL (venereal disease research laboratory) titer of 1:256 and a positive TPPA (treponema pallidum particle agglutination test) at presentation. Histologic exam showed the dense perivascular inflammatory infiltrates composed of lymphocytes, histiocysts and neurophils with some plasma cells in the underlying upper and reticular dermis. Obliterated blood vessels with eosinophilic materials were observed as an unusual histologic feature of syphilis. Based on the clinical, histological and serological findings, a diagnosis of malignant syphilis accompanied by acquired immune deficiency syndrome (AIDS) was made. The patient was treated with intramuscular benzathine penicillin G at 2.4 million units per week for 3 weeks, and the skin lesions completely healed with post-inflammatory hyperpigmentation. It is necessary to take into account this entity among the possible diagnoses in HIV-infected patients with cutaneous noduloulcerative lesions. (Korean J Dermatol 2011;49(1):68~71)
ㄷㅅㅂㄱ(다시보기) 문화를 반영한 링크 보관 애플리케이션
임은정(Eun Jung Im),이수영(Soo Young Lee),이채영(Chae Yeong Lee),이지현(Ji Hyun Lee),추성민(Sung Min Choo),이지훈(Ji Hoon Lee),이정연(Jung Yeon Lee),심완기(Wangi Sim) 한국HCI학회 2014 한국HCI학회 학술대회 Vol.2014 No.12
본 연구에서는 국내 한 커뮤니티의 ㄷㅅㅂㄱ 문화현상을 반영하여 링크 보관 애플리케이션을 디자인하였다. 정보의 유통 속도가 빨라지면서 흘러가는 콘텐츠를 보관하기 위한 니즈가 커지고 있다. 다양한 보관 기능 및 서비스가 등장하고 있지만, 사용자는 보관 기능을 사용하지 않고 스크린샷, 나만 보기 공유등 다른 형태로 콘텐츠를 보관하는 경우가 많다. 네이버 카페 "디젤매니아" 커뮤니티에서 처음 등장한 ‘ㄷㅅㅂㄱ" 현상도 이러한 사례 중 하나이다. ‘ㄷㅅㅂㄱ"는 ‘다시보기"라는 뜻을 가지고 있다. 다시 보고 싶은 글에 ‘ㄷㅅㅂㄱ"라는 댓글을 달고, 나중에 내가 남긴 목록을 통해 콘텐츠를 확인한다. 이미 서비스에서 보관 기능을 제공하고 있었음에도 불구하고 사용자들이 이를 사용하지 않고, 커뮤니티 내 문화를 만들어 보관 욕구를 해결한 것은 이례적인 일이다. 따라서 본 연구에서는 ㄷㅅㅂㄱ(다시보기) 문화 현상이 반영하고 있는 콘텐츠 보관 욕구를 파악하고 이를 바탕으로 링크 기반의 콘텐츠 보관 애플리케이션을 제언하고자 한다.
학문 목적 학습자들의 읽기 능력 향상을 위한 교육 방안 연구
이소현 ( Lee¸ So-hyun ),이정연 ( Lee¸ Jung-youn ) 이중언어학회 2021 이중언어학 Vol.84 No.-
The purpose of this study is to propose a method of teaching Korean reading to improve reading comprehension skills and lead to self-directed learning for foreign students studying at Universities. Reading activities play a critical role in university studies, and students themselves must read and understand actively in order to ensure success in their classes. Therefore, the teacher’s role in a Korean Reading class is to help students understand the content of the writing and lead them to study actively on their own. This study applied a CALLA (cognitive academic language learning approach) instructional model to Korean Reading classes, especially focused on the activities of the ‘practice’ and ‘self-evaluation’ stages of this model. In these stages, strategies practice papers and self-inspection papers were used in class. Experiments were conducted to verify the effectiveness of this method. The experiments were conducted during two classes of Korean Reading 2. As a result, the experimental group improved their reading ability significantly, while the control group did not. This method was especially effective for students with low reading skills. In a follow-up survey, learners responded that all of the students in the experimental group said that the “strategies practice materials” and “self-inspection paper” helped them to better perform in the class. The knowledge gained about their current abilities as it relates to how to read, and reading speed, helped them to improve. Experimental results show that the teaching methods proposed in this study improve students’ reading comprehension and are particularly effective for students with low reading skills. (Ajou University Ewha Womans University)
김재현 ( Jae-hyun Kim ),전태영 ( Tae-young Jeon ),김규완 ( Kyu-wan Kim ),김민송 ( Min-song Kim ),김해진 ( Hae-jin Kim ),박연아 ( Yeon-a Park ),방주희 ( Ju-hee Bang ),윤수 ( Soo Yoon ),이정연 ( Jung-yeon Lee ) 대한신경치료학회 2016 신경치료 Vol.20 No.3
Purpose The purpose of this study was to compare the muscle tone of resting and maximum contraction of biceps brachii in young adults. Methods 77 persons(man 26, female 51) were measured the muscle tone using a myotonometer(Myoton Pro) in resting and maximal contraction state on the both muscle bellies of the biceps brachiies, and compared the muscle tone the dominant with non_dominant hands, resting with maximal contracted states. Results There were statistically significant differences the muscle tone 1.5times between resting and maximal contraction(p<.05)(effect size=1.5), but there were no statistically differences the muscle tone variation values between dominant and non_dominant sides on resting and maximal contraction in biceps brachiies. Conclusion This study can show the standards the muscle tone of resting and maximal contraction, and to help identify the meaning of the neurological and musculoskeletal disorders.
Kyoung Sin Lee,Jung Hyun Park,이화정,Sandy Rhie,이정연 한국약제학회 2012 Journal of Pharmaceutical Investigation Vol.42 No.6
The objective of the present investigation is to examine the effects of rifampicin, which is a P-glycoprotein (P-gp) and cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics of risperidone and its active metabolite,9-hydroxyrisperidone, in rats. To determine the plasma levels of risperidone and 9-hydroxyrisperidone in rats, a high performance liquid chromatographic method was developed using a liquid–liquid acid back extraction. After pretreated with rifampicin (600 mg/kg) for 6 days, the mean Cmax and AUC0–10 values of risperidone were significantly decreased and the Clt of the drug was significantly increased compared with control (p\0.01,\0.05, and\0.05, respectively). The Cmax and AUC0–424 of 9-hydroxyrisperidone were also significantly decreased compared with control (p\0.01,respectively). Thus, the relative bioavailability of risperidone and 9-hydroxyrisperidone once pretreated with rifampicin (600 mg/kg) was 42.5 and 32.5 %, respectively. The exposure of rifampicin significantly decreased oral bioavailability and affected the pharmacokinetics of risperidone and its active metabolite, 9-hydroxyrisperidone, by the induction of P-gp and CYP3A4 as well.