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데스크탑 규모의 간결한 롤투롤 나노임프린팅 기반 나노패턴 연속가공 시스템 개발
이정수(Jeongsoo Lee),이지훈(Jihun Lee),남승범(Seungbum Nam),조성일(Sungil Cho),조용수(Yongsu Jo),고민석(Minseok Go),이승조(Seungjo Lee),오동교(Dong Kyo Oh),김정대(Jeong Dae Kim),이재혁(Jae Hyuk Lee),옥종걸(Jong G. Ok) 한국기계가공학회 2017 한국기계가공학회지 Vol.16 No.1
We have developed a compact desktop-sized nanopatterning system driven by the Roll-to-Roll (R2R) nanoimprinting (NIL) principle. The system realizes the continuous and high-speed stamping of various nanoscale patterns on a large-area flexible substrate without resorting to ponderous and complicated instruments. We first lay out the process principle based on continuous NIL on a UV-curable resin layer using a flexible nanopatterned mold. We then create conceptual and specific designs for the system by focusing on two key processes, imprinting and UV curing, which are performed in a continuous R2R fashion. We build a system with essential components and optimized modules for imprinting, UV curing, and R2R conveying to enable simple but effective nanopatterning within the desktop volume. Finally, we demonstrate several nanopatterning results such as nanolines and nanodots, which are obtained by operating the built desktop R2R NIL system on transparent and flexible substrates. Our system may be further utilized in the scalable fabrication of diverse flexible nanopatterns for many functional applications in optics, photonics, sensors, and energy harvesters.
온톨로지의 상호운용성을 위한 온톨로지 아키텍처에 관한 연구
이정수(Jeongsoo Lee),채희권(Heekwon Chae),김광수(Kwangsoo Kim),김철한(Cheol-Han Kim) 한국전자거래학회 2008 한국전자거래학회지 Vol.13 No.1
온톨로지는 사람들 간의 정확한 의사소통을 가능하게 하고 시스템 사이의 상호운용성을 달성하기 위한 도구로서 다양한 분야에서 많은 기대를 받고 있는 기술이다. 온톨로지의 구축은 기존 온톨로지들 간의 통합을 통해 더욱 효율적으로 이루어질 수 있다. 그러나 기존 온톨로지들이 표현 언어, 대상 도메인, 온톨로지 구성요소 등의 측면에서 다양한 형태와 특성을 가지므로, 온톨로지 통합이 이루어지기 위해서는 온톨로지들 간의 상호운용성의 확보가 필수적이다. 본 논문에서는 온톨로지를 분류하는 체계적인 프레임워크의 제공을 통해 온톨로지들 간의 상호운용성 확보를 지원하는 온톨로지 아키텍처를 제안한다. 본 논문에서 제안하는 온톨로지 아키텍처는 온톨로지를 바라보는 3가지 관점에 따라 온톨로지 메타계층 분류축, 시맨틱 도메인 분류축, 온톨로지 구성요소 분류축의 3개의 분류축으로 이루어져 있다. 온톨로지 아키텍처의 3개의 분류축은 온톨로지들 간의 문법적인 상호운용성과 의미적인 상호운용성을 향상시키기 위해 조화롭게 설계됨으로써 온톨로지 통합이 유연하게 이루어지도록 지원한다. Ontologies are expected in various areas as promising tools to improve communication among people and to achieve interoperability among systems. For communications bet-ween different business domains, building an ontology through integrating existing ontologies is more efficient way than building the ontology without them. However, integration of ontologies is very struggling work since languages, domains, and structures of ontologies are different from each other. In this paper, we suggest an Ontology Architecture which solves this problem by providing a systematic framework to classify ontologies from three kinds of viewpoints:language, domain range, constructs. The Ontology Architecture consists of 3 axes according to the 3 viewpoints:Ontology Meta Layer axis, Semantic Domain Layer axis, and Ontology Constructs Layer axis. Because 3 axes in Ontology Architecture are designed to improve the syntactic and semantic interoperability among ontologies, the integration of ontologies can be readily achieved.
VDRL 역가 변화를 기준으로 시행한 Syphilis 치료 약제의 효과 비교
이정수 ( Jeongsoo Lee ),나누리 ( Nuri Na ),박준수 ( Joonsoo Park ) 대한피부과학회 2020 大韓皮膚科學會誌 Vol.58 No.9
Background: Despite the increasing number of syphilis cases, there has been a considerable lack of recent data comparing the efficacy and duration of benzathine penicillin G, ceftriaxone, and tetracycline in Korean patients. Objective: To compare the efficacy and duration of benzathine penicillin, ceftriaxone, and tetracycline in Korean patients with syphilis. Methods: We retrospectively reviewed 145 cases of syphilis from 2004 to 2019 and statistically analyzed the treatment efficacy and duration. Results: Patients in the benzathine penicillin, ceftriaxone, and tetracycline treatment groups showed no significant statistical difference in terms of treatment rate (chi-square test, p=0.962). Similarly, treatment duration among groups was not statistically significant (one-way analysis of variance, p=0.792). Co-infection with human immunodeficiency virus resulted in reduced treatment rate (p=0.016) and increased treatment duration (p=0.007). Conclusion: This retrospective study showed no significant difference between penicillin, ceftriaxone, and tetracycline in terms of treatment rate and duration. However, a difference in treatment rate and duration was evident between the non-infection and HIV co-infection groups. (Korean J Dermatol 2020;58(9):590∼595)