경피적 신생검 494 예에 대한 임상 및 병리학적 고찰

이윤정(Yun Jeong Lee),정찬(Chan Chung),김은수(Eun Soo Kim),정성권(Kwoen Sung Jung),주권욱(Kwon Wook Joo),차미경(Mi Kyung Cha),이종호(Jong Ho Lee),하승연(Seung Yeon Ha),오영하(Young Ha Oh),이현순(Hyun Soon Lee) 대한신장학회 2001 Kidney Research and Clinical Practice Vol.20 No.1

경피적 신생검은 신장 질환의 중요한 진단 수기의 하나로 널리 이용되며 병리조직학적 소견은 치료 방침 결정이나 예후 판정에 중요한 지표가 된다. 저자들은 1989년 1월부터 1999년 6월까지 가천의대 길병원 내과에서 경피적 신생검을 시행했던 494명을 대상으로 임상 및 병리학적 특성을 후향적으로 분석하여 다음의 결과를 얻었다. 연구 대상의 남녀비는 1.3:1이었고, 연령은 평균 33.2±14.9세이었으며, 총 494에 중 470예(95.1%)에서 병리학적 진단에 충분한 신조직을 얻었다. 신생검의 적응증은 신증후군이 159예(42.3%), 단백뇨와 혈뇨가 58예(15.4%), 육안적 혈뇨가 49예(13.0%), 현미경적 혈뇨가 33예(8.8%), 단백뇨가 8예(2.1%)이었으며, 이식신 신생검은 28예(7.5%)에ㅔ서 시행되었다. 원발성 사구체 신염은 IgA 신병증이 175예(39.5%), 미세 변화 신질환84예(19.0%), 막성 사구체 신염 34예(7.7%), 초점성 분절성 사구체 경화증 33예(7.5%) 순이었고, 이차성 질환군에서는 낭창성 신염 21예(4.7%), B형 간염 바이러스와 연관된 사구체 신염 11예(2.4%), Henoch-Schonlein purpura 9예(2.0%), 당뇨 4예(0.9%) 순이었다. 임상적으로 무증상 요이상을 보인 99예에서 IgA 신병증이 69예(69.7%)로 가장 많았으며, 초박기저막 질환(thin basement membrane disease)이 12예(12.1%)였다. 신증후군의 조직소견으로는 미세 변화 신질환 60예(37.7%), IgA 신병증 25예(15.7%), 초점성 분절성 사구체 경화증 23예(14.5%), 막성 사구체 신염 21예(13.2%), 낭창성 신염 13예(8.2%)의 순이었다. 신생검의 합병증은 육안적 혈뇨가 23예, 신주위 혈종이 6예, 감염 단독이 4예, 감염과 신주의 혈종이 동반된 경우가 1예에서 관찰되었다. 결론적으로, 경피적 신생검을 시행한 환자 중, 일차성 사구체질환에서는 IgA 신병증이 가장 많았고, 이차성 사구체질환에서는 낭창성 신염이 가장 많았다. Percutaneous renal biopsy is an essential component for diagnosis and management of glomerular dis- eases. In order to elucidate clinical and pathological features, 494 renal patients who had undergone renal biopsies at Gil Medical Center from January 1989 to June 1999 were studied retrospectively. The male to female ratio was 1.3: 1 and average age was 33.2 years. There were 370(83.5%) cases of primary glo- merular disease and 58(13.1%) cases of secondary glomerular disease. Among primary glomerular dis- ease, IgA nephropathy was the most common(175 cases), followed by minimal change disease(84 cases), membranous glomerulonephritis(34 cases), and focal segmental glomerulosclerosis(33 cases). In secondary glomerular disease, lupus nephritis was the most common(21 cases), followed by 11 cases of hepatitis B associated glomerulonephritis, 9 cases of HenochSchonlein purpura, and 4 cases of diabetic nephropathy. Among 99 cases of asymptomatic urinary abnormalities, IgA nephropathy was most common(69 cases) followed by 12 cases of thin basement membrane disease, 4 cases of minimal change disease, and 3 cases of focal segmental glomerulosclerosis, membranous glomerulonephritis, nonspecific glomerulonephritis. Among 159 cases of nephrotic syndrome, minimal change disease was most common(60 cases) followed by 25 cases of IgA nephropathy, 23 cases of focal segmental glomerulosclerosis, 21 cases of membranous glomerulonephritis, and 13 cases of lupus nephritis. Documented complication of renal biopsies included 23 cases of gross hematuria, 6 cases of perirenal hematoma, and 4 cases of infection. Death, AV fistula, aneurysm or serious compications that required surgical intervention were not reported. In conclusion, the percutaneous renal biopsy is relatively safe, and useful for diagnosis and management of glomerular diseases. The most common type of primary glomerular disease was IgA nephropathy.

BIM 기반 에너지성능평가를 위한 국내 표준 매개변수 설정 방안에 대한 연구

이윤정(Yun-Jeong Lee),이권형(Kweon-Hyoung Lee),김인한(In-Han Kim),추승연(Seung-Yeon Choo) (사)한국CDE학회 2015 한국CDE학회 논문집 Vol.20 No.1

Currently, the United States, the United Kingdom, Australia etc. are actively utilizing energy simulation for efficiency evaluation of building energy. However, domestic energy efficiency assessment system doesn’t use energy simulation system properly at present: parameters based architecture plans and Ashrae Standard are inputted for the evaluation, because the input parameters for the simulation haven’t been established yet. This fact causes poor reliability during energy simulation, as the values of the two standards are different from each other. Therefore, the aim of the study is to set domestic standard parameter for BIM-based energy performance evaluation, focusing on possession area per person of occupants at government office in Korea. We found that the difference among the result values occurred approximately 3% in the energy simulation. As a result of the analysis, possession area per person of occupants in Government office is 31.87 m2. Other input parameters may be set based on this. This will increase the reliability of energy simulation through a domestic standard parameter.

건축설계 지원을 위한 BIM기반 에너지성능평가의 입력 매개변수 설정에 대한 연구

이윤정(Lee, Yun-Jeong),이권형(Lee, Kweon-Hyoung),김인한(Kim, In-Han),추승연(Choo, Seung-Yeon) 대한건축학회 2014 대한건축학회 학술발표대회 논문집 Vol.34 No.2

공동주택의 일조평가방법 개선 및 BIM기반 검증방법 연구

이윤정(Lee, Yun-Jeong),서지효(Seo, Ji-Hyo),추승연(Choo, Seung-Yeon) 대한건축학회 2013 대한건축학회 학술발표대회 논문집 Vol.33 No.2

유니폼 실태조사 및 디자인 개선을 위한 연구 (Ⅱ)

남윤자(Yeon Ja Nam),김경인(Kyung In Kim),이윤정(Yeon Jeong Lee) 한국복식학회 1997 服飾 Vol.33 No.-

Uniform is getting increased importance as one of the symbols which represent the characteristic of company as well as gives good impression to the customers. Uniform shows the kinds of companies and forms of jobs, and it makes the people who is putting on the uniform feel the sense of unity, a security of one`s position and the companionship, and also it gives him a sense of responsibility and elevates the efficiency of tasks. It is required to be designed for a uniformity, and it can contribute in the increase of work efficiency and help the company get the good results of the management by inspiring the workers with conceit and belongingnesses. The purpose of this study is as the followings : 1) Through the practical survey, we analyze workers`, staffs` and consumers` preference for uniform design. 2) We analyze the fashion trend for 97/98 A/W. 3) We present each uniform design for seven different types of company on the basis of 1) (design preference) and 2) (fashion trends).

늘어지는 영아 증후군의 임상 양상 분석 및 진단적 접근(2008-2012)

설연아(Yeon ah Sul),염미선(Mi Sun Yum),이윤정(Yun Jeong Lee),김은희(Eun Hee Kim),고태성(Tae Sung Ko),유한욱(Han Wook Yoo) 대한소아신경학회 2014 대한소아신경학회지 Vol.22 No.3

Purpose: Floppy infant, or congenital hypotonia, is caused by various diseases, such as genomic disorders, diseases involving the central or peripheral nervous system, musculoskeletal diseases, and metabolic disorders. We describe here the clinical aspects and the final diagnosis of infants with hypotonia recently diagnosed in a single, tertiary-care hospital in Korea. Methods: All of the infants evaluated for generalized hypotonia between 2008 and 2012 at Asan Medical Center Children's Hospital were included in our study. The demographic data, physical examination upon initial presentation, the diagnostic tests and results, and the final diagnosis were retrospectively reviewed. Results: A total of 128 infants (68 males, 60 females) were included in the study, and the mean patient age at the time of the diagnosis of hypotonia was 4.8 months. Etiological diagnosis was possible in 80 (62.5%) of the 128 patients, and 57 (44.5%) patients were confirmed by genetic testing. Fifteen patients (11.7%) were categorized as having central nervous system disorders, and 34 (26.6%) patients were diagnosed as having other genomic disorders such as Prader-Willi syndrome (n=17). Disease involving muscle and the peripheral nervous system was detected in 16 (12.5%) patients. Five patients were diagnosed with other skeletal disorders, and metabolic disease was detected in 10 (7.8%) patients. Conclusion: With the recent advances in diagnostic tools, including genetic testing, many of the patients with hypotonia can be correctly diagnosed. These data can give practical clues regarding the optimal diagnostic approaches for treating floppy infants in the clinics.

실존적 현상학적 관점에서 본 안무의 구성요소

이연수(Yeon Soo Lee),이윤정(Yoon Jeong Lee) 한국여성체육학회 2002 한국여성체육학회지 Vol.16 No.1

Human becomes to conceive the body-embodied space through body image. Although human conceives body, the body owes the space which contain work directions and particular movement. That space is not an objective space or spatial location, but spatial situation or experienced space through body-image. Therefore the body motion which human has is not only a movement, but a kind of structural phenomena, that human body motion has a conception of static object at stacked moment and separates this conceptive world into shape-background. As long as human isn`t able to separate time, body and acts through time in the world, time is not separable moment being at the side of human, but existing present with human himself, future ahead of human, past lagged behind human. Time, world and human can`t be separated as body and consciousness. Time, space and movement are continuous with one another. Movement, whether time is fast or slow, is revealed as an extreme of one of these or a gradation in between. In the same way movement takes space too whether space is big or not. If movement in dance is perceived as imaginary linear pattern which is originated from creative force in human body, time and space in dance is basically creative one. Time-Space in dance can`t be separable, and can`t be measurable as general time-space can. Dancer and spectator will all take part in an special experience which is made from body of time. Consequently, time-space in dance is imaginative and poetic, moving one. dance is not simple flowing time sequence, but creative, energetic formative procedure, then dancer is to be dancing body by selected movement, which creates new time and space. Spectator will experience dynamic force and image in dance by participating dancing body.

국내 인허가용 BIM 모델 가이드라인 개발을 위한 기초연구

이권형(Lee, Kweon-Hyoung),이윤정(Lee, Yun-Jeong),추승연(Choo, Seung-Yeon) 대한건축학회 2014 대한건축학회 학술발표대회 논문집 Vol.34 No.2

국내 BIM 발주 건축 현상공모경기의 Green BIM Data 활용 현황 분석

이주식(Jusik Lee),추승연(Seung-Yeon Choo),이권형(Kweon-Hyung Lee),류정림(Jung-Rim Ryu),이윤정(Yun-Jeong Lee) (사)한국CDE학회 2015 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2015 No.동계

The necessity for Eco-friendly Low-Carbon Design technology has been emphasized by the government and scholars since the crisis of environmental problem. BIM is a great technology for Low-Carbon Design in architecture. The architectural competitions in Korea have a limitation on the way of evaluation because it’s just evaluate by the checklists and not consider for the architecture design elements. The guidelines for BIM in competition not using BIM data for energy performance simulation but just for viewing and checking models. For this reason, this study analyzed the BIM architectural competition guidelines within the framework of BIM data utilization. Purpose of this study is to measure the possibility of BIM data to be using for eco-sector assessment through energy performance simulation. First, this research analyze guidelines of 4 architectural competitions. Second, draw eco-sector assessment elements of those BIM competition. Third, measure the possibility for energy performance simulation based BIM data utilization.

Enterovirus 71 Brainstem Encephalitis Presenting with Pulmonary Hemorrhage and Acute Heart Failure

이명숙(Myoung Sook Lee),김은희(Eun Hee Kim),이윤정(Yun Jeong Lee),오기원(Ki Won Oh),이경연(Kyung Yeon Lee) 대한소아신경학회 2014 대한소아신경학회지 Vol.22 No.3

Enterovirus 71 has been recognized as being highly central nervous system (CNS) involved and presents with diverse neurologic manifestations. Brainstem encephalitis is the most common neurologic manifestation of CNS involvement by enterovirus 71, and manifests myoclonus, ataxia, tremor, and autonomic dysfunction such as pulmonary hemorrhage. Here we report a 31-month-old girl with enterovirus 71 brainstem encephalitis presenting with pulmonary hemorrhage and acute heart failure. The patient was admitted to emergency department of our hospital due to high-grade fever, vomiting, myoclonus, and tremor 4 days after hand, foot and mouth disease. Four hours after admission, the patient presented with pulmonary hemorrhage and acute heart failure. CSF analysis demonstrated white blood cell 60/mm3, red blood cell 1/mm3, protein 43.0 mg/dL, and glucose 149 mg/dL. Despite aggressive management including intravenous immunoglobulin, milrinone and empirical antimicrobial therapy, the patient died due to uncontrolled pulmonary hemorrhage and shock in 15 hours after admission at emergency department. In stool specimen obtained from the patient, enterovirus 71 (subgenotype C4a) was detected. This case suggests that an early diagnosis of central nervous system involvement in patient with enterovirus 71 infection is vital because brainstem encephalitis resulting from enterovirus 71 infection can rapidly progress to the critical state of disease.