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자궁경부 선양낭성암종의 세포학적 소견 - 1예 보고 -
하승연,조현이,오영하,류근신,Ha, Seung-Yeon,Cho, Hyun-I,Oh, Young-Ha,Lyu, Geun-Shin 대한세포병리학회 1998 대한세포병리학회지 Vol.9 No.2
Adenoid cystic carcinoma of the uterine cervix is a rare tumor accounting for less than 1% of all cervical adenocarcinoma. This tumor is characterized by aggressive biological behavior with frequent local recurrence or metastatic spread, postmenopausal onset, and occasional association with conventional squamous cell carcinoma. The cytologic diagnosis of adenoid cystic carcinoma in the uterine cervix is often difficult because of negative smear due to intact overlying mucosa, cytologic findings mimicking endometrial cells, and masquerade as squamous ceil carcinoma. Recently we have experienced a case of adenoid cystic carcinoma arising in the uterine cervix, which was identified on the routine Papanicolaou smear and was histologically confirmed by the consequent biopsy. The smear showed abundant cellularity composed of relatively uniform cells. The tumor cells were arranged in small clusters, acini, naked cells, and loose sheets with abortive cribriform pattern. There were scattered globoid basement membrane-like materials and tumor diathesis. The nuclei were pleomorphic and showed hyperchromatic and coarsely granular choromatin with inconspicuous nucleoli. The punch biopsy of the uterine cervix showed typical histologic findings of adenoid cystic carcinoma characterized by tumor nests composed of hyperchromatic uniform basaloid cells, cribriform pattern, and cylindrical hyaline bodies.
하승연,조현이,오영하,Ha, Seung-Yeon,Cho, Hyun-I,Oh, Young-Ha 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.2
Pulmonary alveolar proteinosis(PAP) is a rare disease in which the alveolar spaces are filled with an eosinophilic, PAS-positive material, whereas the interstitial architecture of the lung usually remains unaffected. Although a definitive diagnosis is usually made by an open lung biopsy, bronchoalveolar lavage(BAL) cytology may play a decisive role in the diagnosis and therapy of these patients and may spare a patient a more invasive diagnostic procedure. The author presents a patient in whom BAL cytology specimen contained the characteristic globules of amorphous proteinaceous PAS-positive material accompanied by background of rare macrophages and inflammatory cells. Ultrastructural study using BAL specimen can confirm the diagnosis of PAP.
흉추에서 발생한 척삭종의 세포학적 및 조직학적 소견 - 1예 보고 -
하승연,김인선,박성혜,박흠례,Ha, Seung-Yeon,Kim, In-Sun,Park, Sung-Hye,Park, Heum-Rye 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.2
Chordoma is relatively uncommon tumor comprising $1\sim4%$ of primary malignant bone tumors, and believed to arise from the remnants of notochordal tissue. Because of its rare occurrence in the thoracic spine, we report a case of chordoma involving the thoracic spine. A 45-year-old male was sufferred from chest pain radiating to the back. Chest CT showed a well marginated, round huge mass with multiseptated enhancement at the thoracic spine from T5 to T8 level. After percutaneous needle aspiration, piecemeal resection of the tumor was done. On cytologic smears, two types of neoplastic cells were arranged in sheets and cords in mucinous background. One type of cells consisted of medium sized cells with pink cytoplasm and round nuclei. The other type had voluminous bubbly or clear cytoplasm divided by intracytoplasmic septae imparting a feathery or basket-like appearance. Histologically, the tumor showed lobulated feature divided by fibrous septae and the tumor cells were pink eosinophilic or physaliphorous in morphology. Immunohistochemically, the tumor cells revealed strong positivity for low(AE1) and high (AE3) molecular weight cytokeratins.
하승연(Seung Yeon Ha),이연희(Yun Hee Lee) 한국복식학회 2012 服飾 Vol.62 No.3
Interest in the environment is rising in all the sectors of industry and culture. Even in the fashion industry, fashion designers have recently begun delivering messages on the environment. In particular, Issey Miyake has been constantly interested in environmental issues, and has been deemed as a designer who values practicality and universality in clothing. This study seeks to examine Issey Miyake`s fashion from the perspective of an eco-friendly design. This research analyzed collections of Issey Miyake from 1980 to 2010 through photo works and www.firstview.com. The research method was to study 8 people who have professionalism in fashion design and have analyzed 201 works of Issey Miyake from 1980s to 2000s that have the characteristics of eco-friendly design. The results showed the following characteristics of eco-friendly design in Issey Miyake`s fashion : naturality, simplicity, sustainability and transformability. First, Issey Miyake preferred natural materials and used Japan traditional dyeing that integrated modern techniques for naturality. Second, he expressed simplicity in his fashion by applying the least cutting and sewing in geometric panels. Third, he pursued sustainability with comfortable clothing that anyone could wear regardless of trend, age and body shape. Finally, he developed the A-POC system that eliminated the usual needs for cutting and sewing and tried transformability on clothing using buttons, strings, belts, zippers, and layered styling.
하승연 ( Seung Yeon Ha ),이기범 ( Ki Beom Lee ),이순표 ( Soon Pyo Lee ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.10
Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor that usually arises within the gastrointestinal tract. However extragastrointestinal stromal tumor (EGIST) is a rare tumor (5%), especially few cases of EGIST arising in vagina have currently been reported in the literature. We have experienced a case of vaginal GIST. A 49-year-old female presented with vaginal mass for three weeks. The mass was located posterolateral vagina near to introitus and 3.0 × 2.5 cm in size. Histological examination showed hypercelluar spindle cell proliferation and more than 10 mitoses per 50 high power fields. They were positive for c-kit (CD 117) and CD34. Surgery is the most effective treatment and long term follow up is warranted.