삼초(三焦)의 '협관계(協關系)' 관점에서 본 측두하악관절(側頭下顎關節)에 대한 고찰

이영준,이종수,이한성,Lee, Young-Jun,Lee, Jong-Soo,Lee, Han-Sung 척추신경추나의학회 2005 대한추나의학회지 Vol.6 No.1

Objectives : The aim of this study was to try to embody the method of treating Tempromandibular Joint Disorder in Oriental Medicine. Methods : I had researched anatomic features and functions of TMJ, causes and symptoms of TMD and reviewed classic medicine books in Oriental Medicine on Sanjiao. Then, I tried to interpret the disorder in the point of Sanjiao's 'Cooperative Relationship'. Results and Conclusions : 1. Symptoms of TMD IS not limited at TMJ and spread in whole body by circulation of Sanjiaojing. 2. Sanjiao is a invisible organ to control the general physical functions as 'Cooperative Relationship'. 3. It is a due in improving the symptoms of TMD to regulate Sanjiao-Jing-qi and balance the Yin-Yang.

FCST의 음양균형장치를 활용 삼차신경통 증례보고

이영준,이상배,박민철,이화정,인창식,Lee, Young Jun,Lee, Sang-bae,Park, Min-Cheol,Lee, Hwa Jeong,Yin, Chang Shik 턱관절균형의학회 2015 턱관절균형의학회지 Vol.5 No.no.sup

본 증례에서는 극심한 삼차신경통 진단을 받고 안면부와 턱관절 통증으로 일상생활이 어려워 항간질약과 수술적 치료를 받았지만 통증이 개선되지 않던 환자에게서 음양균형장치를 포함한 자세조절훈련, 침치료 등 구조적 치료를 통해서 유의한 자각적 증상 개선뿐만 아니라 턱관절의 구조적 개선이 나타남을 관찰하였고, 요통과 경항통 및 비염 같은 제반 증상들의 호전과 척추의 구조적 개선이 관찰되었다. Therapeutic effect of Yinyang Balancing Appliance (YBA) of functional cerebrospinal therapy (FCST) for meridian and neurologic yinyang balance was observed in a trigeminal neuralgia case. One Trigeminal neuralgia case was managed with YBA on temporomandibular joint (TMJ), combined with acupuncture. Clinical outcome measurement was performed by subjective rating and clinical observations. The patient's subjective rating and clinical symptoms showed improvement immediately after the initial treatment and this improvement maintained over the follow-up period. Although it is not clear whether the effect is temporary in its nature, a positive effect was observed and further clinical and biological research on FCST is expected.

FCST의 구강내 균형장치를 이용한 경추부 근긴장 이상증 증례보고

이영준,인창식,Lee, Young Jun,Yin, Chang Shik 턱관절균형의학회 2016 턱관절균형의학회지 Vol.6 No.1

경추부 근긴장 이상증에 대해 턱관절 자세균형 개념에 따라 구강내 균형장치를 활용한 자세훈련법 등의 치료로 긍정적인 호전을 관찰했다. 증례 보고이기는 하지만 턱관절 자세균형을 활용한 치료법에서 긍정적인 치료효과가 이어지고 있어서 앞으로 더욱 체계적인 관찰과 연구가 필요할 것으로 사료된다. To investigate the effects of the postural balance of TMJ using intraoral balancing appliance of functional cerebrospinal technique (FCST) combined acupuncture and manual medicine therapeutics in the treatment of congenital muscular torticollis. An idiopathic cervical dystonia case was managed with postural training with intraoral balancing appliance, combined with acupuncture and manual medicine therapeutics. Clinical assessment included radiography, Toronto Western Spasmodic Torticollis Rating Scale, and global clinical impression. Clinical improvement was observed over 5 months of treatment period. Clinical observational data on spasmodic torticollis provide an positive prospective for further investigation on the effect of FCST.

제올라이트 5A 와 활성탄에 대한 CH4 와 CO 의 흡착평형

이영준,양재영,이창하 ( Young Jun Lee,Jae Young Yang,Chang Ha Lee ) 한국화학공학회 1996 화학공학의이론과응용 Vol.2 No.2

주류업계의 이미지 제고를 위한 제언

이영준,Lee, Yeong-Jun 한국주류산업협회 2000 주류산업 Vol.20 No.2

고수압 조건에서 쉴드터널 세그먼트 라이닝 구조설계에 관한 연구

이영준,김기림,정건웅,홍의준,김선홍,전덕찬,Lee, Young-Joon,Kim, Ki-Lim,Jeong, Keon-Woong,Hong, Eui-Joon,Kim, Seon-Hong,Jun, Duk-Chan 한국터널지하공간학회 2015 한국터널지하공간학회논문집 Vol.17 No.3

양호한 암반조건이나 균질한 점토지반 등 불투수성 지반의 경우에도 불연속면에 의하여 수압이 작용될 수 있으므로, 설계시 지반조건에 상관없이 수압조건을 고려하고 있다. 그러나, 세그먼트 라이닝의 형상이 원형임에 따라 수압을 고려하는 경우가 오히려 라이닝에 발생되는 부재력을 감소시킬 수가 있으므로, 고수압 조건에서는 이에 대한 설계개념정립이 중요하다. 따라서, 본 논문에서는 고수압의 불투수성 지반조건에서 하중조건 및 하중조합에 따른 부재력 크기 등을 비교함으로서, 세그먼트 라이닝 설계시 합리적이고 적절한 설계개념에 대하여 서술하였다. In impermeable ground, water pressure is applied due to discontinuity such as joint or fissure. Therefore, water pressure should be considered in design regardless of ground condition. However, when the shape of segmental lining is circular, water pressure may reduce the lining member force, so it is important to define the assumption and the concept of design in case of high water pressure. This paper presents the concepts of design of the lining of shield tunnel at high water pressure and in impermeable ground condition. In addition, the member forces in various load conditions were compared in this study. (elastic equation, closed form solutions, beam-spring model).

Effect of Gongjindon a Traditional Korean Polyherbal Formula, on the Pharmacokinetics Profiles of Donepezil in Male SDRats (1) -Single Oral Combination Treatment of Donepezil 10mg/kg with Gongjindan 100mg/kg within 5 min-

이영준,구세광,Chung, Dae-Kyoo,Kwon, Oh-Dae,Park, Soo-Jin,Lee, Young-Joon,Ku, Sae-Kwang 대한예방한의학회 2013 대한예방한의학회지 Vol.17 No.1

Objectives : This study was aim to evaluate effects of pharmacodynamics and toxicity in combination therapy of donepezil with Gongjindan. Methods : After 10mg/kg of donepezil treatment, Gongjindan 100mg/kg was administered within 5 min. The plasma were collected at 30min before administration, 30min, 1, 2, 3, 4, 6, 8 and 24hrs after end of Gongjindan treatment, and plasma concentrations of donepezil were analyzed using LC-MS/MS methods. PK parameters of donepezil were analysis as compared with donepezil single administered rats. Results : Gongjindan markedly inhibited the absorption of donepezil regardless of sample time, from 30min to 8hrs after end of co-administration comparing with donepezil single treated rats. Especially the absorption of donepezil was significantly decreased at 2hrs after co-administration as compared with donepezil single treated rats, in the present study. Accordingly, the Cmax(-27.76%), $AUC_{0-t}$(-27.22%) and $AUC_{0-inf}$(-26.54%) of donepezil in co-administered rats were significantly decreased as compared with donepezil single treated rats, respectively. Conclusions : Based on the results of the present study, co-administration of Gongjindan decreases the oral bioavailability of donepezil by inhibiting the absorption. It is considered that the more detail pharmacokinetic studies should betested to conclude the effects of Gongjindan on the pharmacokinetics of donepezil, when they were co-administered, like the effects after co-administration with reasonable intervals considering the Tmax of donepezil and after repeated co-administrations.

Synergic Effects of Mixed Formula Consisted of Polycan and Calcium-gluconate on the Experimental Periodontitis and Alveolar Bone Loss in Rats

이영준,구세광,Lee, Won-Ho,Kim, Kyung Hu,Kang, Su Jin,Lee, Young Joon,Ku, Sae Kwang 대한예방한의학회 2014 대한예방한의학회지 Vol.18 No.1

Objective : Polycan, exopolymers purified from Aureobasidium pullulans SM-2001 and calcium gluconate have been showed favorable inhibitory effects on the periodontitis and related alveolar bone losses through antioxidant and anti-inflammatory activities, respectively. In the present study, we intended to observe the possible synergic effects of mixed formula consisted of Polycan and calcium gluconate on ligation-induced experimental periodontitis and related alveolar bone losses in rats, and to select the fittest compositions for further developing as effective agents to ameliorate periodontal diseases. Method : Experiments were conducted as two separated two tests - first is synergic effects of Polycan and calcium gluconate 1:1, 1:9 and 9:1 mixtures, and second is 1:99, 2:98, 4:96, 8:92 and 1:9 mixtures. Experimental periodontal diseases were induced by ligature placed around the cervix of upper left incisior teeth of rats. One day after ligation placements, 200mg/kg of each single or mixed formulas of Polycan or/and calcium gluconate were orally administered for 10 days. The changes on the alveolar bone loss index and maxillary bone mineral density (BMD) were observed for detecting alveolar bone losses, and for anti-inflammatory effects, myeloperoxidase (MPO) activities and proinflammatory cytokine (tumor necrosis factor; TNF-${\alpha}$) contents were also evaluated in gingival tissues around ligature placed incisior teeth. The results of mixtures were compared with those of singe Polycan and calcium gluconate treated rat. Results : Each single or mixed formulas of Polycan or/and calcium gluconate favorably and significantly inhibited the inflammatory changes. The inhibitory effects of mixed formula consisted of Polycan and calcium gluconate 1:9 showed against periodontitis and related alveolar bone losses as compared with those of each Polycan and calcium gluconate single formula (p<0.05). In second experiment, Polycan and calcium gluconate 2:98, 4:96, 8:92 and 1:9 mixed formulas also showed significant increased anti-inflammatory and inhibitory effects against alveolar bone losses as compared with those of each single formula. Among them, Polycan and calcium gluconate 2:98 showed the highest efficacy against to ligation-induced experimental periodontitis and related alveolar bone losses. Conclusion : The results obtained in this study suggest that appropriated mixtures of Polycan and calcium gluconate showed synergic inhibitory effects against ligation-induced experimental periodontitis and related alveolar bone losses in rats. Moreover, Polycan and calcium gluconate 2:98 showed the highest efficacies in this experiment, suggesting the fittest composition for further developing as effective agents to ameliorate periodontal diseases.

기업경영에의 인터넷 활용

이영준,Lee, Yeong-Jun 한국주류산업협회 1996 주류산업 Vol.16 No.3

12~19세기 한의학 고전문헌에 나타난 턱관절 구강내장치에 대한 고찰

이영준,이상배,최근욱,인창식,Lee, Young-Jun,Lee, Sang-Bae,Choi, Geun-Wook,Yin, Chang Shik 턱관절균형의학회 2014 턱관절균형의학회지 Vol.4 No.1

Objectives: Intraoral appliances (IOA) are applied in the clinical practice of Korean medicine to improve the balance between yin and yang of the body such as temporomandibular joint balancing medicine. Historical examples of IOA were not well known. This study reports prototype IOA's described in medical classics. Methods: Several medical classics of 12th to 19th centuries were narratively reviewed for prototypical descriptions of IOA's in the context of clinical practice. Results: IOA's in the medical classics reviewed adopted such materials as bamboo, chopsticks, and coins that were adjusted in the height and were used as a temporary IOA's with response of the patient being monitored. IOA's were applied integratively with herbal medicine for diverse complaints such as pain, hearing problem, cough, asthma, and rhinorrhea. Conclusions: Prototype IOA's in the medical classics suggest an individualized, integrative, and holistic principle and usage of IOA's in the tradition of Korean medicine.