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김영생 ( Young Saeng Kim ),구본호 ( Bon Ho Ku ),최유경 ( Yu Kyung Choi ),김종훈 ( Jong Hun Kim ),손희정 ( Hee Jung Sohn ),백소야 ( So Ya Paik ),이예리 ( Ye Ri Lee ) 대한내과학회 2009 대한내과학회지 Vol.76 No.5
젖유사샘(mammary-like glands)은 정상적으로 존재하는 외음부 피부 구조물이나 잘 알려져 있지 않다. 이 조직은 아직까지 기능이 불분명하고 에크린샘, 아포크린샘, 젖샘 등과 구별되는 특징을 가지고 있다. 1936년에 Greene에 의해 젖유사샘으로부터 유래한 샘암종이 처음 보고되었고, 이후 약 20여 증례가 보고된 바 있다. 이에, 저자들은 외음부에서 발생한 원발성 젖유사샘암종을 국내에서 최초로 보고하는 바이다. 외음문의 가려움증과 종괴를 주소로 내원한 62세 여자 환자로, 간과 뼈에 다발성 전이가 동반되어 있었다. 외음부와 간종괴의 조직 검사상 유방의 침윤성관암종(invasive ductal carcinoma)과 유사한 소견을 보였으며, 에스트로겐 수용체, 프로게스테론 수용체, HER-2, GCDFP-15 면역염색이 모두 양성이었다. 유방 초음파와 자기공명영상을 촬영하였으나 유방은 정상 소견을 보였다. 따라서 유방의 침윤성관암종과 유사한 조직 소견을 가지는 외음부에 발생한 원발성 젖유사샘암종이 간과 뼈에 전이된 것으로 진단하였다. 환자는 뼈 통증으로 방사선 치료를 받던 중 진단 7주만에 폐렴으로 사망하였다. Mammary-like glands are poorly recognized structures of normal vulvar skin. Here, we report the first case of primary mammary-like gland adenocarcinoma of the vulva in Korea and discuss the differential diagnosis and treatment of this rare tumor. A 62-year-old woman presented with an itching sensation and palpable mass of the vulva. Abdominal computed tomography showed multiple variable-sized nodules with peripheral rim enhancement in the liver. The pathology of the vulva and liver lesions was consistent with invasive ductal carcinoma of the breast, with positive staining for estrogen receptors, progesterone receptors, HER-2, and GCDFP-15. Ultrasonography and magnetic resonance imaging of the breast were normal. Given the histological findings in conjunction with the absence of a breast lesion, a diagnosis of primary mammary-like gland adenocarcinoma of the vulva was made. She died of pneumonia 7 weeks after the diagnosis. (Korean J Med 76:605-610, 2009)
김영생(Young Saeng Kim),이종원(Jong Won Lee),임병천(Byung Chun Yim) 한국유럽학회 2000 유럽연구 Vol.11 No.1
The social system and it`s dynamics bring the structural process changes enormously. They acquire competence to survive and remain competitive under the market economic conditions. One of the main problems during the recent development of financial institutions in Europe and Korea is that the organizational structure is not able to grow simultaneously and organizational forms are not adequate to the changed new environments. As results there are lags in the handing over informations and missing clear definition of areas of competence. Beside many technical changes by the implementation of new technologies the dynamic system theory especially self-organization was improved as successfiil also in financial institutions.
윤상후,이영생,박정수,Yoon, Sang-Hoo,Lee, Young-Saeng,Park, Jeong-Soo 한국통계학회 2009 Communications for statistical applications and me Vol.16 No.1
It is necessary to forecast the amount of the maximum electricity demand for stabilizing the flow of electricity. The time series data was collected from the Korea Energy Research between January 2000 and December 2006. The data showed that they had a strong linear trend and seasonal change. Winters seasonal model, ARMA model were used to examine it. Root mean squared prediction error and mean absolute percentage prediction error were a criteria to select the best model. In addition, a nonstationary generalized extreme value distribution with explanatory variables was fitted to forecast the maximum electricity. 한국의 경제규모가 꾸준히 커감에 따라 가정, 건물, 공장 등에서 필요로 하는 전력량이 지속적으로 증가하고 있다. 전력공급의 안정화를 위해서는 최대전력량보다 전력공급능력이 높아야 한다. 월별 최대전력량을 잘 설명할 수 있는 통계모형을 찾기 위해 Winters 모형, 분해 시계열모형, ARMA 모형, 설명 변수를 통해 추세성분과 계절성분을 교정한 모형을 살펴보았다. 모형의 예측력 비교 기준으로 모형적합으로부터 구한 RMSE와 MAPE가 사용되었다. 여름철 최대전력량을 예측하기 위해 평균기온과 열대야 일수를 설명 변수로 갖는 시계열 모형이 가장 우수하였다. 아울러 외부요인을 갖는 극단분포 모형을 이용한 분석을 시도하였다.
증례 : 감염 ; 장게실염에 동반된 Streptococcus viridans와 Bacteroides fragilis 균혈증에 의한 문맥염 1예
구본호 ( Bon Ho Ku ),김영생 ( Young Saeng Kim ),김종훈 ( Jong Hun Kim ),최유경 ( Yu Kyong Choi ),연재우 ( Jae Woo Yeon ),이성규 ( Seong Gyu Lee ),김수연 ( Sue Yun Kim ) 대한내과학회 2009 대한내과학회지 Vol.76 No.5
문맥염은 증상이 다양하고 비특이적이어서 조기 진단이 어렵고, 치료시기를 놓치면 높은 치사율을 보이기 때문에 빠른 진단과 치료가 예후에 중요한 질환이다. 저자들은 지속되는 발열을 주소로 내원한 환자에서 게실염에 동반되어 나타난 S.viridans와 B.fragilis 균혈증에 의한 문맥염을 발견하였고, 항생제 치료만으로 호전되어 퇴원한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Pylephlebitis, a septic thrombophlebitis of the portal vein or one of its tributaries, is a life-threatening complication of intra-abdominal infection. The causes of pylephlebitis include acute diverticulitis, appendicitis, acute cholecystitis, necrotizing pancreatitis, inflammatory bowel disease, and bowel perforation. Although pylephlebitis is an unusual complication of diverticulitis, its morbidity and mortality remain high. Therefore, early diagnosis and initiation of adequate antibiotic therapy is important for improving the long-term prognosis of patients suffering from this rare disease. We report a case of pylephlebitis with Streptococcus viridans and Bacteroides fragilis bacteremia secondary to diverticulitis with a review of the literature. (Korean J Med 76:622-626, 2009)
이상준(Sang Joon Lee),정필상(Phil-Sang Chung),김영생(Young Saeng Kim),윤경섭(Kyung Sub Yun) 대한두경부종양학회 2007 대한두경부 종양학회지 Vol.23 No.2
Objectives :Well differentiated thyroid carcinoma(WDTC) has relatively good prognosis. But recurrence is associated with increased morbidity and mortality, and always results in reoperation. So it is important to evaluate the risk factors relative to the recurrence. The aim of this study is to evaluate the risk factors of recurrence. Materials and Method :Two hundred seventeen patients who had undergone thyroidectomy and proved as WDTC from January 1999 to December 2004 was included in the study. We reviewed patient-related and tumor-related factors respectively and analyzed the correlation with tumor recurrence. Results :Fourteen patients from two hundreds seventeen had recurred. Recurrence rate was 6.5%, and aver-age interval of recurrence was 28 month. Male, age over 45, multiple mass, and advanced TMN stage patient group show higher recurrence rate, but no statistical significance. However, the recurrence rate of lymph node metastasis, tumor size >1.5cm, and extracapsular invasion group were statistically high. Conclusion :Lymph node metastasis, tumor size and extracapsular invasion are significant risk factors re-lated to the recurrence of WDTC.
에너지 손실을 최소화한 실내공기 정화용 판-형 열교환기 개발 및 성능평가
이대희(Dae Hee Lee),박재석(Jae Suk Park),김영생(Young Saeng Kim),배종렬(Jong Ryeol Bae) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11
We have developed a new innovative plate-type heat exchanger using thin aluminum foil sheet that significantly reduces the indoor pollutants with a minimum loss of energy. The thin aluminum foil sheet has a thickness of 17㎛, a width of 330 ㎜, and a length of 1,510 ㎜. The heat exchanger consists of 45 layers of aluminum foil sheets which are placed on top of each other with a spacing of 7 ㎜. The exchanger is structured such that air dust and pollutants can be effectively filtered as the air stream passes through the heat exchanger. The experimental results show that the carbon dioxide concentration inside the office room reduces to as low as 650 ppm, while maintaining the room temperature difference to within ± 1 degree Celsius before and after operating the new heat exchanger. This device can be installed in any indoor places that need to maintain a good air quality with a minimum energy loss.