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      • SCOPUSKCI등재

        희박-과농 메탄 화염의 상호작용에 관한 수치해석적 연구

        이승동,정석호,Lee, Seung-Dong,Jeong, Seok-Ho 대한기계학회 1996 大韓機械學會論文集B Vol.20 No.1

        Interaction of flames in a lean-rich concentration field is studied numerically adopting a counterflow as a model problem. Detailed kinetic mechanism is adopted in analyzing the structure of various type of flames which can be found in lean-rich interaction. Flow field is simplified to quasi one-dimensional by using boundary layer approximation and similarity formulation. Triple flames are identified and its structure shows that a diffusion flame is located in the middle of two premixed flames. Such a diffusion flame is formed by $H_2$ and CO generated from the rich premixed flame and $O_2$ leaked from the lean premixed flame. The flame position can be identified either from the hydrogen production rate or the heat release rate. Transition from single diffusion flame to triple flame is observed as degree of premixing is increased.

      • SCOPUSKCI등재

        Cyclosporine과 Tacrolimus 국소도포로 치료한 Ofuji 구진홍반

        이승동 ( Seung Dong Lee ),조은아 ( Eun Ah Jho ),강훈 ( Hoon Kang ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.8

        Papuloerythroderma of Ofuji isa rare and unique form of erythroderma and usually affects elderly Asian men. Various therapeutic approaches have been tried and both systemic corticosteroids and PUVA have been reported to be most effective. A 57-year-old man presented with itchy erythematous papules forming erythroderma that did not affect skin folds. His lesion did not respond to topical corticosteroids and antihistamines for 2 weeks. We used cyclosporine and topical tacrolimus. He completely recovered several days later and there has been no sign of recurrence for nearly 1 year. (Korean J Dermatol 2009;47(8):934~936)

      • KCI등재

        정서,행동장애연구 : 자기교시훈련 프로그램이 자폐성장애 학생의 문제행동에 미치는 영향

        이승동 ( Seung Dong Lee ),정훈영 ( Hoon Young Jung ) 한국정서·행동장애아교육학회(구 한국정서학습장애아교육학회) 2012 정서ㆍ행동장애연구 Vol.28 No.4

        본 연구의 목적은 자기교시훈련 프로그램이 자폐성장애 학생의 상동행동과 공격행동 감소에 어떠한 영향을 미치는가를 알아보는 것이다. 연구 목적을 달성하기 위해 서울 소재 H특수학교에 재학 중인 고등학교 자폐성장애 학생 3명을 선정하였으며, 실험설계는 대상자간 중다기초선(multiple baseline across subject)을 실시하였다. 구성절차는 자기교시훈련 3단계 중 용암적 자기교시방법을 중심으로 자폐성장애 학생의 특성에 맞게 재구성하였고, 훈련과제의 내용은 문제행동 빈도를 감소시키기 위하여 표준화 검사인 KISE-KIT(Korea Institute for Special Education-KoreaIntelligence Test for Children: 한국형 개인 지능검사)의 소항목 중 이름 기억하기, 숨은 그림 찾기, 동작성 검사로 칠교놀이, 그림 무늬 만들기를 일부 활용하였으며, 이러한 훈련과제를 중심으로 하여 인지적 모델링 훈련→외현적 지도 훈련 →외현적 자기지도 훈련→외현적 자기지도 감소 훈련→내현적 자기지도 훈련 등과 같은 절차를 기초선, 실험처치, 유지의 순서로 실시하였다. 연구를 통해 얻은 결과는 다음과 같다. 첫째, 자기교시훈련 프로그램은 대상 학생 3명의 상동행동을 감소시키는데 긍정적인 효과가 있었다. 둘째, 자기교시훈련 프로그램은 대상 학생 3명의 공격행동을 감소시키는데 긍정적인 효과가 있었다. 본 연구를 통해 자기교시훈련 프로그램을 통한 교수전략이 자폐성장애 학생의 문제행동을 감소시키는데 긍정적인 영향이 있음을 보여준다. The purpose of this study was to investigate how self-instructional training has an effect on the behaviors of autistic children. In this research, the subjects were 3 children with autism who are attending the special school located in Songpa-gu, Seoul. A multiple probe design across subjects was used as Single Subject Experiment Designs, which can be easily utilized in the educational practice. With focusing on those kinds of training program, the sequence of experiment was base line period, experimental treatment, and maintaining to carry out the order of cognitive modeling, overt instruction, overt self-instructional training, reduction of covert self-instruction training, and covert self-instructional training. The results of this study were as follow: First, The stereotyped behavior was drastically reduced after applied the The self-instruction training program. The effect was maintained and generalized. Second, The aggressive behavior was drastically reduced after applied the The self-instruction training program. The effect was maintained and generalized. This pattern study proved magnetically that self-instruction training program had an effect in the problem behavior intervention of autistic disorder student.

      • KCI등재

        스플라인 기어류의 폐쇄단조 해석

        이승동(Seung-Dong Lee),김원일(Won-Il Kim),김용조(Yohng-Jo Kim) 한국산업융합학회 1999 한국산업융합학회 논문집 Vol.2 No.2

        Closed-die forging of spline was analysed using the upper bound elemental technique, Two different forging methods, denoted here as side extrusion-forging and upset forging, were proposed, The kinematically admissible velocity fields for each of the forging methods, which could express trapezoidal, rectangular and serration tooth forms, were presented. Upper bounds to forging loads and deformed configurations were predicted using the velocity fields. Theoretical results were compared with experimental ones. Experiments with lead were carried out at room temperature where grease was used as a lubricant. The present investigation revealed that analytical forging loads were reduced by using the side extrusion-forging but the upset forging could improve configuration of the final forged splines.<br/>

      • SCOPUSKCI등재

        모기질종의 β-catenin 유전자 이상

        이승동(Seung Dong Lee),이현정(Hyun Jeong Lee),김진우(Jin Wou Kim),하석준(Seog Jun Ha),김정수(Jung Soo Kim) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.1

        N/A Background:β -catenin muations were reported to play a causal role in the development of pilomatricomas. In a recent study in Caucasians, 75% of pilomatricomas had β -catenin mutations. Objective:We investigated the causal role of β -catenin gene mutations in pilomatricomas of Koreans. Methods:This study included 20 formalin-fixed, paraffin-embedded pilomatricomas in Koreans. Basophilic nucleated tumor cells were microdissected and, as normal controls, infiltrating inflammatory lymphocytes were microdissected from the same histologic specimens. Sequencing analysis of exon 3 of the β -catenin gene (CTNNB1) was performed. Immunostaining for β -catenin and Lef-1 was performed by the avidin-biotin-peroxidase method. Results:Sequencing analysis found missense mutations (S37Y, S37C, S33C, S33F, and S37F) in CTNNB1 in 6 samples (30%) of 20 pilomatricomas. All pilomatricomas revealed intense expression of nuclear Lef-1 and nuclear and cytoplasmic β -catenin. Conclusion:Frequencies of β -catenin mutations were lower in our study compared with the results in Caucasians. The immunohistochemical results suggest the abnormalities in Wnt-wingless pathway resulting in stabilization or constitutive expression of β -catenin, but the absence of CTNNB1 mutations in 70% of our cases suggests adenomatous polyposis coli gene inactivation, or the involvement of other components of the Wnt-wingless pathway. (Korean J Dermatol 2002;40(1):14~18)

      • KCI등재
      • SCOPUSKCI등재

        괴저고름피부증에 대한 임상적 고찰

        이승동 ( Seung Dong Lee ),이지현 ( Ji Hyun Lee ),김경문 ( Kyoung Moon Kim ),유동수 ( Dong Soo Yu ),박철종 ( Chul Jong Park ),박영민 ( Young Min Park ),조상현 ( Sang Hyun Cho ),이준영 ( Jun Young Lee ),강훈 ( Hoon Kang ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.8

        Background: Pyoderma gangrenosum (PG) is a rare noninfectious skin disorder characterized by chronic recurrent painful ulcers. Because of its low incidence and diagnostic difficulty, there were few comprehensive studies of the clinical features of PG in Korea. Objective: Our purpose was to delineate the clinical features of PG. Methods: 22 patients who presented with PG at 6 hospitals of Catholic Medical Center over ten years were enrolled in this study. We reviewed all medical records of the patients. Results: The mean age was 47.9 years. The male to female ratio was 1:1.4. Cases in children account for 2 out of twenty two. Sixty-one percent of the patients had lesions on their lower legs. The typical ulcerative variant was found in 19 patients, bullous PG in 3 patients. An association with other internal diseases was noted in 9 patients. Two cases were developed in heavy alcoholics. 15 patients were treated with systemic corticosteroid, 12 cases with systemic corticosteroid only, one case with systemic corticosteroid and cyclosporine, one case with systemic corticosteroid and dapsone, one case with systemic corticosteroid, cyclosporine and colchicine. 1 patient was treated with cyclosporine and colchicine, 1 patient with colchcine, rifampicin and antibiotics. Five cases were treated with antibiotics only. In the only systemic corticosteroid therapeutic group, the response rate was 83%. 3 patients experienced recurrence and 3 patients showed positive pathergy reactions. Conclusion: PG is a rare disease with the ulcerative variant being most frequent. The lower legs were the most commonly affected sites. PG was accompanied with systemic disease in 46% of the cases. Comparing with foreign literature, the response rate of treatments was generally fine and the recurrence rate was low. (Korean J Dermatol 2008;46(8):1028~1035)

      • SCOPUSKCI등재

        탈모증 환자에서 미녹시딜 용액 사용 실태에 관한 이메일 설문 조사

        이승동 ( Seung Dong Lee ),강태욱 ( Tae Wook Kang ),박영민 ( Young Min Park ),김시용 ( Si Yong Kim ),김형옥 ( Hyung Ok Kim ),강훈 ( Hoon Kang ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.2

        Background: Topical minoxidil solution is very well known and easily obtainable stuff in Korea. Even though it is an useful and effective medication for keep the hairs, there are still some misunderstandings exist. Objective: To assess the general awareness and usage status of topical minoxidil solution in alopecia patients. Methods: E-mails with questionnaire file were sent to 3,875 patients who visited the hair clinic. 202 replied questionnaires were enrolled in this study. The questionnaire consisted of 30 items concerning the general evaluation of the awareness and usage status of topical minoxidil. Results: The proper candidates for the minoxidil solution including male pattern hair loss, female pattern hair loss, and some alopecia areata felt that it was relatively effective. But most patients who had not seen a doctor misunderstood the usage and side effects of topical minoxidil. Also this group`s satisfaction of topical minoxidil solution was lower than that of the group who had consulted a doctor. Some patients with heart problems (10.4%) had been used topical minoxidil solution without any caution. Conclusion: Although topical minoxidil solution is an over-the-counter medicine, careful explanation of its usage and side effects should be provided before application. To make sure and increase its exact effectiveness, the role of dermatologist should be emphasized. (Korean J Dermatol 2008;46(2):216∼223)

      • SCOPUSKCI등재

        안병변, 전경골 점액수종, 선단비대의 삼징후를 보인 그레이브즈 병

        이승동 ( Seung Dong Lee ),이지현 ( Ji Hyun Lee ),강훈 ( Hoon Kang ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.9

        Graves` disease is an autoimmune disorder of the thyroid gland and the most common cause of hyperthyroidism. Classic clinical findings include ophthalmopathy (exophthalmos), dermopathy (pretibial myxedema) and thyroid acropachy. The triad of Graves` clinical findings occurs in less than 1% of Graves` patients. We present a case of Graves` disease with the clinical triad of exophthalmos, pretibial myxedema, and thyroid acropachy. (Korean J Dermatol 2008;46(9):1253~1256)

      • SCOPUSKCI등재

        국소 스테로이드 제제 사용에 관한 대학 병원 피부과외래 환자의 인식도 및 행태 설문 조사

        김세연 ( Sei Yeon Kim ),이승동 ( Seung Dong Lee ),김형옥 ( Hyung Ok Kim ),박영민 ( Young Min Park ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.4

        Background: Topical steroids are a widely used therapeutic agent in dermatology. However, little objective data has been collected in order to assess the awareness, knowledge and behavior of patients regarding the use of topical steroids. Objective: The goal of this study was to investigate the current state of awareness, knowledge, and behavior of patients regarding topical steroid use. Methods: A written questionnaire was distributed to 570 outpatients who visited the dermatologic clinics of the University Hospital. Of these, 504 were appropriate and thus were included in this study for further statistical analysis. The questionnaire consisted of 26 items concerning the overall evaluation of the awareness, and behavior of outpatients regarding their use of topical steroids. Results: The results demonstrated that of 504 patients included in the analysis, 53.8% bought topical steroids with a dermatologist`s prescription, whereas 33.6% obtained their topical steroids without prescription. The patient recognition rate of brand name, therapeutic effects, and side effects of topical steroids was 58%, 77% and 26%, respectively. Twenty percent of patients who have used topical steroids complained of side effects, the most common of which being pruritus (7.5% of cases). More than half of the patients said they obtained their information about topical steroids from sources other than the dermatologist. More than three quarters of patients (77%) applied topical steroids 1-2 times per day, whereas the overusers (4%) and the long-term users (16%) were applying topical steroids more than 5 times a day and longer than 16 weeks, respectively. Conclusion: The results indicate that topical steroids have been used without sufficient information and guidelines. Taken together, it is suggested that dermatologists should more thoroughly explain the therapeutic effects, indications, and side effects of topical steroids to their patients. (Korean J Dermatol 2008;46(4):473~479)

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