스테레오 기법을 이용한 차량의 검출 및 추적에 관한 연구

尹世鎭(Sei-Jin Yoon),禹東玟(Dong-Min Woo),孔吉永(Gil-Young Kong) 대한전기학회 2000 전기학회논문지 D Vol.49 No.12

위장관 ( 胃腸管 ) : 우리나라에서 흉골하작열감 내지 흉통의 원인으로서 식도운동성질환의 중요성에 관한 연구

윤용범(Yong Bum Yoon),송인성(In Sung Song),김정룡(Chung Yong Kim),최상운(Sang Woon Choi),최규완(Kyu Wan Choi),노임환(Im Hwan Roe),윤세진(Sei Jin Youn),정현채(Hyun Chae Jung),김용태(Yong Tae Kim),김나영(Na Young Kim) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.1

N/A Aims of this study are to investigate the proportion of esophageal motility disorder as the cause of heartburn and/or chest pain, to evaluate the relationship among the diagnostic tools for gastroeso-phageal reflux disease(GERD) such as manometry, esophagoscopy, Bernstein test and 24 hour esophageal pH monitor and to evaluate the usefullness of each test in the diagnosis of gastroeso-phageal reflux disease by estimating its sensitivity and specificity based on 24 hour esophageal pH monitor. For this study, 106 patients with heartburn and/or chest pain and 32 controls were enrolled. The results were as follows; 1) Of 106 patients with heartburn and/or chest pain, 36 patients (34#%) have GERD and 6 patients (5.6%) have Nutcracker esophagus as a cause of this symptom. 2) One hundred and six patients were divided into the two groups on the basis of LES pressure, one comprising 14 patients with LES pressure lower than 11 mmHg and the other 92 patients with the higher LES pressure; then the group of the lower LES pressure was found to have the smaller amplitude and the shorter duration of peristaltic waves, and the higher positive rates of esophagos-copic finding. Bernstein test and 24 hour esophageal pH monitor than the other group. On the basis of reflux esophagitis finding in esophagoscopy the same 106 patients were divided into two groups, one comprising 18 patients with positive esophagoscopic finding and the other 88 patients with negative esophagoscopic finding; then the group of positive esophagoscopic finding was found to have the smaller amplitude and shorter duration of peristaltic waves, the lower LES pressure and the higher positive rate of Bernstiein test and 24 hour esophageal pH monitor than the other group. 3) The sensitivity and the specificity, evaluated with reference to the 24 hour esophageal pH monitor, were 53.6% and 90% respectively for Bernstein test, and 25% and 90% respectively for the low LES pressure. From these results, we are led to the conclusions that firstly the occupying rate of the esophageal motility disorder was 39.6% as a cause of heartburn and/or chest pain, secondly there was a relationship among the diagnostic tools for GERD, and thirdly the 24 hour esophageal pH monitor is not needed only for the diagnosis of GERD when the LES pressure was below 11 mmHg or Bernstein test was positive.

위장관 ( 胃腸管 ) : 한국인에 있어서 대장용종

윤용범(Yong Bum Yoon),송인성(In Sung Song),최규완(Kyoo Wan Choi),김정룡(Chung Yong Kim),이효석(Hyo Suk Lee),윤세진(Sei Jin Youn),정현채(Hyun Chae Jung),김용태(Yong Tae Kim),김나영(Na Young Kim) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.2

N/A The present report analyzed a series of 767 polyps from 15,000 cases who wore undogone colonos- copy or sigmoidoscopy at the dept, of internal medicine, Seoul National Universily Hospital from June 1976 to Dec. 1989. The results are as follows. 1) The prevalence of colorectal polyp was 5,1% (767 cases out of 15,000 cases) and increased from 1976 to 1989. 2) The most common symptom was anal bleeding (27%). 3) The 43 cases out of 203 cases (21%) revealed a positive finding in occult blood examination of stool, and 88 cases out of 158 cases (55%) turned out to have polyps in colon study. 4) The most common histologic type of polyp was adenomatous (49%) and the most common gross iype was Yamada type II (30.%). 5) Eleven cases out of 30 cases (36.9%) whose polyps were over 2 cm in diameter were villous adenoma, and 4 cases out of 11 cases (36%) had a foci of cancer. Ten cases out of 245 cases (4%) whose polyps wore under 1 cm in diameter were villous adenoma, and the foci of cancer were not seen. These figure suggest that as polyps grow, the risk of villous adenoma and cancer increase. 6) When we compared endoscopic findings with histologic types in polypectomized specimens, 9 cases (64%) out of 14 cases were diagnosed as hyperplastic polyp by only endoscopy, and 68 cases (91%) out of 75 cases were diagnosed as adenomatose polyp by only endoscopy. 7) Six cases (4.4%) out of 135 cases in tubular, four cases (16.6%) out of 24 cases in villotubular, four cases (19%) out of 21 cases in villous adenoma, were colorectal cancer with polyp remnant, respectively. The annual prevalence of colorectal polyp increased and endoscopy was superior to Barium enema in diagnosing colorectal polyps. For prevention of colorectal cancer, more effort should be done in detecting and eradicating colorectal polyps.

십이지장 궤양 출혈의 내시경 지혈술 후 발견된 분리췌장

최용혁 ( Yong Hyeok Choi ),윤순만 ( Soon Man Yoon ),김은비 ( Eun Bee Kim ),오영민 ( Youngmin Oh ),김근모 ( Keunmo Kim ),이지선 ( Jisun Lee ),박선미 ( Seon Mee Park ),윤세진 ( Sei Jin Youn ) 대한소화기학회 2017 대한소화기학회지 Vol.69 No.4

Peptic ulcer bleeding is treated using endoscopic hemostasis using clips or bands. Pancreas divisum (PD), a congenital anomaly of the pancreas, usually has no clinical symptoms; however, pancreatitis may occur if there are disturbances in the drainage of pancreatic secretions. We report an unusual case of PD accompanied by acute pancreatitis, following endoscopic band ligation for duodenal ulcer bleeding. A 48-year-old woman was admitted to our hospital due to melena. An upper endoscopy revealed a small ulcer with oozing adjacent minor papilla. An endoscopic band ligation was performed on this lesion. Acute pancreatitis developed suddenly 6 hours after the band ligation and improved dramatically after removal of the band. Magnetic resonance cholangiopancreatography was performed, revealing complete PD. Endoscopic band ligation is known as the effective method for peptic ulcer bleeding; however, it should be used carefully in duodenal ulcer bleeding near the minor duodenal papilla due to the possibility of PD. (Korean J Gastroenterol 2017;69:248-252)

종양과 연관되어 발생한 근병증 2예 요약제목: 종양관련 근병증 2예

이효덕 ( Hyo Deok Lee ),김미진 ( Mee Jin Kim ),서의근 ( Eui Geun Seo ),채희복 ( Hee Bok Chae ),한정호 ( Joung Ho Han ),윤순만 ( Soon Man Yoon ),박선미 ( Seon Mee Park ),윤세진 ( Sei Jin Youn ),김대곤 ( Dae Ghon Kim ) 전북대학교 의과학연구소 2012 全北醫大論文集 Vol.36 No.1

저자들은 근병증 2예와 병발한 악성 종양을 경험하였으며, 향후 원인 미상의 간 효소 수치 상승을 가진 환자가 피부 병변과 근력 약화를 호소하는 경우 꼭 근육염 가능성을 염두에 두어야 한다는 교훈을 얻을 수 있었다. 아울러 이러한 환자에서 근육염 확진을 위한 근육 생검, 근염 특이 자가 항체 검사 등을 통해서 IIM으로 진단될 경우 종양의 동반유무를 찾기 위한 종양표지자 및 영상 검사와 함께 PET 등의 첨단 검사도 이용될 필요가 있다는 것을 저자들은 본 2예의 증 례보고를 통해서 주장하는 바이다. 감사의 글 본 증례 환자들의 치료 과정을 함께 해 주시고, 원고를 검토해주신 류마티스 내과 강귀영 교수님께 진심으로 감사 드립니다. It is assumed that malignancy is a part of a clinical course in patients with idiopathic inflammatory myopathy (IIM), as the cancer occurrence in the group have been frequently reported. This paper discusses two cases of IIM associated with cancer either simultaneously or sequentially. The first patient who had diagnosed with colon cancer two weeks prior to the admission presented with polymyositis (PM). The second patient with breast cancer presented dermatomyositis (DM). Both patients were admitted to the hepatology unit because their initial presentation was abnormal liver enzyme levels with muscle weakness. IIM patients can be misdiagnosed as acute hepatitis because of the initial feature. This paper reports two cases of IIM with malignancy.

팽대부 선근종의 임상적, 병리학적, 면역조직화학염색의 특징

최용혁 ( Yong Hyeok Choi ),김미진 ( Mi Jin Kim ),한정호 ( Joung Ho Han ),윤순만 ( Soon Man Yoon ),채희복 ( Hee Bok Chae ),윤세진 ( Sei Jin Youn ),강민호 ( Min Ho Kang ),성노현 ( Rohyun Sung ),최재운 ( Jae Woon Choi ),박선미 ( Seon 대한소화기학회 2013 대한소화기학회지 Vol.62 No.6

Background/Aims: Ampullary adenomyoma is a benign lesion whose malignant potential has yet to be confirmed. Despite its benign nature, adenomyoma is frequently misdiagnosed as a carcinoma or adenoma and is overtreated by extensive surgery. This study was performed to analyze the clinical, pathological, and immunohistochemical features of adenomyomas in the ampulla of Vater. Methods: Nine cases of adenomyoma in the ampulla of Vater, diagnosed in Chungbuk National University Hospital between 2008 and 2011, were enrolled in this study. We reviewed the clinical data on the symptoms, laboratory data, and radiologic findings of the abdominal computed tomography and endoscopic retrograde cholangiopancreatography. For pathological analysis, all the slides were reviewed by one pathologist, and immunohistochemical stainings with antibodies against cytokeratin 7 (CK7), cytokeratin 20 (CK20), α-smooth muscle actin (α-SMA), and Ki-67 antigen were performed. Results: All the cases were CK7 positive and CK20 negative. A strong cytoplasmic expression of α-SMA was confirmed in all cases. The Ki-67 index was less than 1% in eight cases and 5% in one case. Four cases underwent endoscopic papillectomy, and one case received surgical ampullectomy during colorectal cancer surgery. Five cases that underwent endoscopic or surgical treatment remained symptom-free for three years. Four cases that were closely observed with repeated endoscopic examinations exhibited no interval changes in the papillary lesions. Conclusions: Endoscopic biopsy and immunohistochemistry can aid in the diagnosis of ampullary adenomyomas. Endoscopic papillectomy or surgical ampullectomy is adequate for the treatment of symptomatic ampullary adenomyomas. (Korean J Gastroenterol 2013;62:352-358)

증상을 동반한 거대 가성낭종을 형성한 이소성 췌장 1예

박성순 ( Sung Soon Park ),신윤미 ( Yoon Mi Shin ),임성우 ( Seong Woo Lim ),김석형 ( Seok Hyung Kim ),전원중 ( Won Joong Jeon ),박선미 ( Seon Mee Park ),윤세진 ( Sei Jin Youn ) 대한내과학회 2006 대한내과학회지 Vol.70 No.6

이소성 췌장은 모든 위장관에 발생 가능한 선천성 기형으로 대부분이 무증상으로 지내며, 우연히 발견되는 경우가 대다수이다. 저자들은 식후 상복부 복통을 주소로 내원한 22세 여자 환자에서 위의 이소성 췌장에서 췌장염 합병된 가성낭종을 진단하고 수술 후 증상이 호전된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Heterotopic pancreas is the presence of pancreatic tissue that lacks anatomic and vascular continuity with the main body of the pancreas. Most patients with heterotopic pancreas are asymptomatic. Any pathologic change in the normal pancreas also can occur

다중검출 전산화단층촬영에서 담석이 보이지 않는 급성 담석성 췌장염에서 조기 내시경초음파검사의 유용성

박재근 ( Jae Geun Park ),김기배 ( Ki Bae Kim ),한정호 ( Joung-ho Han ),윤순만 ( Soon Man Yoon ),채희복 ( Hee Bok Chae ),윤세진 ( Sei Jin Youn ),박선미 ( Seon Mee Park ) 대한소화기학회 2016 대한소화기학회지 Vol.68 No.4

Background/Aims: EUS can detect bile duct stones (BDS) that are undetectable on multidetector computed tomography (MDCT). BDS associated with acute biliary pancreatitis (ABP) are small and tend to be excreted spontaneously. This study evaluated the usefulness of early EUS in patients with ABP and undetectable BDS on MDCT. Methods: Forty-one patients with ABP and undetectable BDS on MDCT underwent EUS within 24 hours of admission and were diagnosed with BDS, sludge, dilated common bile duct (CBD), or normal CBD. ERCP was performed in patients with BDS, sludge, or clinical deterioration. The diagnostic yield and the effects of early EUS on morbidity, mortality, and the length of hospitalization were evaluated. Results: EUS detected BDS or sludge in 48.8% of patients examined. BDS was the diagnosis in 13 patients, sludge in seven, and neither for 21 patients. ERCP was performed in 20 patients with BDS or sludge, in two patients with coexisting cholangitis, and in one patient with worsening liver function tests. ERCP identified BDS in 12 patients and sludge in seven. No lesions were diagnosed in four patients by ERCP. All patients improved, and the length of hospitalization in patients with ERCP was 9.0 days, without ERCP 7.1 days. Two patients with major complications by ERCP were hospitalized for a prolonged time. Conclusions: Early EUS may be useful to select patients for therapeutic ERCP in cases of suspected ABP with undetectable BDS on MDCT. (Korean J Gastroenterol 2016;68:202-209)

혈액투석 환자에서 활동중혈압을 이용한 투석간 혈압과 수시혈압과의 관계 및 일중 변동에 관한 연구

김혜영(Hye Young Kim),곽남주(Nam Ju Kwack),박남규(Nam Kyu Park),최기원(Ki Won Choi),김동운(Dong Woon Kim),조명찬(Myeong Chan Cho),이상도(Sang Do Lee),윤세진(Sei Jin Yoon),김승택(Seung Taik Kim),엄재호(Jae Ho Earm),남기병(Kee Byung Na 대한내과학회 1996 대한내과학회지 Vol.50 No.4

N/A Objectives: The pre, post and intradialytic blood pressure are used as the criteria of antihypertensive medication in hemodialysis patients but extracellular volume expansion, vasoactive substances released during ultrafiltration and removal of catecholamine make casual blood pressure inaccurate. Furthermore there are reports of the loss of normal diumal blood pressure variation in hemodialysia patients. So we performed this study to evaluate the relationship between interdialytic blood pressure and casual blood pressure measured during dialysis and to find the most representative casual blood pressure in hemodialysis patients. In addition the diurnal blood pressure variations of hemodialysis patients were observed. Methods : We measured interdialytic blood pressure using 24 hour ambulatory blood pressure monitoring(AHPM) and casual blood pressure in the day of dialysis in 21 hemodialysis patients. The increase of body weight during interdialytic period was also recorded. Blood pressure was monitored every 15 min for 24 hours in 21 hemodialysis patients and 50 age and sex matched normal controls. The day-night blood pressure difference was compared between hemodialysis patients and normal controls. Results: 1) The casual pre, intra, postdialytic systolic blood pressure(165.2±26.7 mmHg, 152.7±21.2 mmHg, 160.9±22.5 mmHg, respectively) were significantly higher than interdialytic ambulatory systolic blood pressure (147.9±19.4 mmHg)(p<0.05). 2) The casual pre, intra, postdialytic diastolic blood pressure(94.5±14.8 mmHg, 89.5±15.4 mmHg, 92.4±14.8 mmHg, respectively) were significantly higher than interdialytic ambulatory diastolic blood pressure(77.8±12.2 mmHg)(p<0.05). 3) There were significant relationship between casual pre, intra, postdialytic systolic pressure and interdialytic ambulatory systolic pressure(p<0.01). Correlation coefficients were ranged from 0.67 to 0.78. Hut the only casual postdialytic diastolic pressure was significantly correlated with interdialytic ambulatory diastolic pressure(p<0.01). Correlation coefficients were ranged from 0.56 to 0.58. 4) In normal controls, the daytime blood pressure was significantly higher than nighttime blood pressure(p<0,01) and the day-night difference was 7.1±9.6 mmHg in systolic pressure, and 2.2±6.3 mmHg in diastolic pressure. Hut in hemodialysis patients, that was reversed (p<0.01) and the day- night difference was -4.5±11.7 mmHg in systolic pressure and -1.8±10.2 mmHg in diastolic pressure. Conclusion: The blood pressure measured in the day dialysis was significantly higher than interdialytic ambulatory blood pressure. And the postdialytic blood pressure was significantly related to interdialytic ambulatory blood pressure in both systolic and diastolic pressure. Normal diurnal blood pressure variation was lost in hemodialysis patients.

Virus-associated hemophagocytic syndrome 1예

정지인 ( Jee In Jeong ),박찬선 ( Chan Sun Park ),전원중 ( Won Joong Jeon ),채희복 ( Hee Bok Chae ),박선미 ( Seon Mee Park ),윤세진 ( Sei Jin Yoon ),신경섭 ( Kyoung Seop Shin ) 대한내과학회 2008 대한내과학회지 Vol.75 No.3

EBV와 연관된 virus-associated hemophagocytic syndrome (VAHS)는 초기에 간비종대와 황달의 소견을 보여 다른 소화기 질환과의 감별이 어렵다. 하지만 병의 진행이 급격히 악화되고 갑작스런 사망을 초래하는 매우 불량한 예후를 갖는 치명적인 질환으로 이에 대한 조기 감별진단이 요구된다. 저자들은 EBV와 연관된 임상적 소견과 조직학적으로 Hemophagocytic syndrome (HS)을 보인 VAHS 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Hemophagocytosis refers to the pathologic finding of activated macrophages engulfing erythrocytes, leukocytes, platelets, and their precursor cells. Hemophagocytic syndrome (HS) (more properly referred to as hemophagocytic lymphohistiocytosis) is a distinct clinical entity characterized by fever, pancytopenia, splenomegaly, and hemophagocytosis in the bone marrow, spleen, and lymph nodes. HS is associated with a variety of viral, bacterial, fungal, and parasitic infections, as well as with collagen vascular diseases and malignancies. Epstein-Barr virus (EBV)-associated HS is almost always a fatal disease. The authors present a case of EBV-associated HS. The patient had fever and hepatosplenomegaly and showed pancytopenia, jaundice, and positive EBV viral markers in serum, positive EBV DNA in the liver biopsy specimen, and hemophagocytosis in the bone marrow. The patient died unexpectedly 1 month after admission. We report the details of this case of fatal EBV-associated hemophagocytic syndrome along with a brief review of the literature. (Korean J Med 75:322-326, 2008)