Metal oxide semiconductor field-effect transistor (MOSFET)-based direct monitoring of p53 in spiked serum

오윤광,이창수,Tran Thi Dung,이영희,김문일 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.37 No.-

We describe the direct monitoring of p53 in a human serum sample by a metal oxide semiconductorfield-effect transistor (MOSFET) biosensor. The biomolecular interaction between DNA and p53 proteinwas measured using a DNA-modified MOSFET under the condition of physiological ionic strength. Treated with p53 in serum, a MOSFET exhibited a comparable change in the drain current, while noalteration in response to serum spiked with DNA binding-defective p53 was observed, leading to a goodagreement between theory and experiment. Our data suggest that a MOSFET device can be potentiallyused for the determination of p53 in serum samples on the basis of DNA–protein interaction.

Bioreceptor-Based Field-Effect Transistor (FET) System for Detection of Ethylene

오윤광,김문일 한국진공학회 2018 한국진공학회 학술발표회초록집 Vol.2018 No.2

바이오나노 전자 코

김경호,오윤광,권오석,Kim, Kyung-Ho,Oh, Yun-Kwang,Kwon, Oh-Seok 한국진공학회 2018 진공 이야기 Vol.5 No.1

Electronic nose has been developed for detection of various hazardous molecules, especially vapor organic compounds (VOCs), by adsorption and desorption phenomenon. However, although conventional electronic noses have provided many advantages such as simple detection and high sensitivity, they still need advanced technologies for selective specificity in real samples. In this review, we provide bionanoelectronic noses with natural receptors for selective odorant detection. This review includes from fabrication of natural receptors and conducting nanomaterials to bioelectronic noses. We also discussed their perspective applications for the future at the conclusion.

Gas Sensor-Based Techniques for Detecting Ethylene (C2H4)

Tran Thi Dung,이의진,오윤광,김문일 한국진공학회 2023 Applied Science and Convergence Technology Vol.32 No.4

Ethylene (C2H4) is a crucial plant hormone that regulates fruit ripening and aging. As the only gaseous plant hormone, ethylene has been identified as a significant contributor to produce spoilage, causing economic losses of billions of dollars annually. To address this issue, the development of a biosensor that can accurately and specifically monitor ethylene levels as an indicator of production loss is of paramount importance to the fruit, flower, and vegetable industries, owing to its potential to mitigate losses and increase profits. Consequently, there is an increasing demand for affordable, reliable, and improved methods for rapid and accurate detection and quantification of ethylene. Consequently, the selection of appropriate sensor solutions should specify the requirements and contexts of individual applications. In this review, we explore the recent progress in chemical sensing technologies for ethylene detection and highlight the current research trends and future challenges in this field.

의료기관평가 항목에 관한 중소형병원 약제부서의 역할 재조명

은종영,이영희,김인옥,김현순,윤금희,박태진,박희진,윤성희,장진경,오윤광,서희원,최인옥 한국병원약사회 2009 병원약사회지 Vol.26 No.3

Abstract: The aim whose is important to reduce the business of small and medium sized hospital pharmacist, which is advanced for a medical treatment service every 3 years with problem point of the medical institution evaluation and business, pharmacist possibility, business volume of small and medium sized hospital pharmacy investigates the actual condition about facility and equipment etc. class confirmation analyzes the problem point which follows in the change aspect which is changing, the plan will be able to strengthen a clinical medicine service with patient orient, above constructing the effectiveness and an effectiveness of medicine business, considers the standardization of one document. 2009 year medical institution service evaluation objective hospitals was general hospitals of above 260 windows under 100 windows and hospitals 126 places of above 300 windows, 2008 year objective hospitals were size general hospital 76 places of above 500 windows under 260 windows. The research, 6th 2006 hospital medicine station actual condition investigations, which sees from KSHP executed as the hospital standardization, 2005 medical institution evaluation objective hospitaHbelow and 260~400 windows under 400~499 windows) in the object one evaluation result with base 2007 about the small and medium sized hospital pharmacy which is announced medical institution evaluation result and the actual con dition investigation, About foot withdrawal about present condition(worker, facility etc.) of the small and medium sized hospital medicine station analysis investigates a data from the question analysis for 2009 year second 3rd small and medium sized hospital medical institution evaluation undergoing an examination objective hospitaH117 hospitals) educations and 2008 year medical institution evaluation resultant analyses sees and from based on the data house does and the present situation comparative re-to illuminate. - conclusion - 1) KSHP side First, the hospital pharmacist manpower legal standard which is a current preparation of medicines-possibility standard open a court in patient possibility standard, Second, introduce a hospi-tal pharmacist manpower grade by valence addition system, Three, college of pharmacy estab-lishment and college of pharmacy regular staff increase. 2) small and medium sized hospital medicine station side In order the small and medium sized hospital medicine station overcomes a difficult pending question (manpower supply and grant regulation and business system, automatic computerization etc.) from to investigates a problem point and the application instance (best practice) which and the advanced hospital is optimum to seek, this benchmarking to do and to ask in order to be reflected the understanding of the hospital competent authorities and, conducts the utmost efforts.

2010년도, 중소병원 약제부서 의료기관 인증제 평가문항 관련 현황 분석결과 및 시사점을 통한 향후 개선 방향에 관한 연구

은종영,이영희,김인옥,김현순,윤금희,박태진,박희진,윤성희,장진경,오윤광,서희원,최인옥 한국병원약사회 2010 병원약사회지 Vol.27 No.4

Investigates the actual condition about problem point under medical institution evaluating which is advanced in medical service link and business present condition etc. of the small and medium sized hospital pharmacy the problem point which follows in the change aspect which is changing suddenly confirmation analyzes the patient the effectiveness of the plan will be able to strengthen a clinical medicine service in the center and medicine business constructs to consider the standardization of the document for, the aim whose is important to reduce the business of small and medium sized hospital pharmacist, will do. From like this dimension 2010 year certificate system relation question items in the center 500 bed under small and medium sized hospital question has the result which investigates in the object and Improves a business of the pharmacy station. According to the question item the result which analyzes a question investigation with afterwords is same. Purchase, selection, store, prescription, preparation of medicines and drug administration about the monitor ring has the management guide, (44%), is not like that and (56%) with is becoming and relates with a hereafter with the subject urgent for the business guide which is standardized from the certificate system preparation medicine station to produce from small and medium sized hospital commission dimension about the problem where thinks that the many discussion is necessary. Is the medical institution certificate system evaluation of the small and medium sized hospital medicine station attains meaning of origin and confronts when to observe the maximum subject which tries and the reserves which pharmacist manpower is appropriate (80%), the actuality is the estimate of the certificate system evaluation question item which reflects (67%), discrimination education chance provision of the small and medium sized hospital and the large sized hospital of KSHP and supply guide manual which is standardized (64%). When considering the pharmacist manpower which the small and medium sized hospital medicine station is insufficient, the reserves method which is appropriate as what judge does to question actualization of wages (65%), the interest which the authorities is continuous and benefit provision (55%), the reserves effort which the hospital is continuous (is 50%) etc. Also most the hereafter small and medium sized hospital medicine station must do the conglomerate`s major goal of key which is renegotiation of manpower standard (58%), in-service training which separate way of the small and medium sized hospital and the large sized hospital is discriminated (36), the interest which KSHP is continuous (is 30%) etc. With the fact hereafter must improve consequently complements a system from KSHP dimension and policy of large sized hospital putting first will be able to own jointly information from the small and medium sized hospital thinks that the education which is discriminated is necessary.