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창포울금탕(菖蒲鬱金湯)으로 호전된 중풍환자 불면증(不眼症) 치험 2례
오용성,임명현,장우석,이소연,박치상,박창국,Oh Yong-Seong,Lim Myung-Hyun,Jang Woo-Seok,Lee So-Yeon,Park Chi-Sang,Park Chang-Gook 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.4
Insomnia is a disorder of initiation and maintenance of sleep that is derived from multiple factors such as psychologic, physiological and environmental problems. A number of stroke patients suffer from insomnia classified as one of the sleep disorders associated with physical illness and on the contrary insomnia may have profound deleterious effects on the natural course of stroke. Sedative-hypnotics including benzodiazepine and non-benzodiazepine have widely been used in chronic insomniacs. However, most hypnotics cause dependence, tolerance, impaired daytime function and rebound insomnia. Therefore, we are looking forward to proposing an effective oriental treatment for insomnia. We report two cases of insomniacs, treated with Changpoulgeumtang. After the treatment, insomnia and other accompanied symptoms were improved.
오가피장척탕(五加皮壯脊湯)을 투여한 43명의 증례보고(症例報告) 및 QSCCII의 태양인(太陽人) 부분의 개선방안(改善方案)
오용성,곽민아,장우석,김봉석,송광규,김승모,박재현,임명현,Oh Yong-Sung,Kwak Min-Ah,Jang Woo-Seok,Kim Bong-Suk,Song Kwang-Kyu,Kim Seong-Mo,Park Jae-Hyun,Lim Myung-Hyun 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.2
Background : Till now Efficacy of Taeyangin medicine have not existsd in Medical Oriental medical, QSCC II(Questionnaire of sasang Constitution Classification II) can't discriminate Taeyangin is known to everybody. Objective : We have made an Effort to find out Essence of Taeyangin's Disease. Method : we have examined patient's feeling of improvement, Disease entity, Term of taking medicine, Period of ilness With eath symptoms, Comparison Taeyangin part Marks of QSSC II with Marks of improved Taeyangin questionnaire. Result : According to 43 Case of Patients Treated with Ogapijangchuk-tang, Ogapijangchuk-tang is more effective to cure Fatigue taking Headache and Dizziness than Myalgia and so on. and Item of more improved Taeyangin's constitution Question is more effective than Item of Taeyanin's constitution question in QSCC II.
백서(白鼠)의 국부(局部) 뇌경색(腦硬塞)에 대한 조구등(釣鉤藤)의 신경보호(神經保護) 효과(效果)
권형수,오용성,이소연,박치상,박창국,장우석,Kwon Hyung-Su,Oh Yong-Seong,Lee So-Yeon,Park Chi-Sang,Park Chang-Gook,Jang Woo-Seok 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.2
The goal of this study is to investigate whether Uncariae Ramulus et Uncus can protect nerve cells against ischemic neuronal damage is caused by middle cerebral artery occlusion (MCAO) in rats' brains and to investigate whether the neuroprotective effect of Uncariae Ramulus et Uncus is concerned with IEGs(immediate early genes) expression. Uncariae Ramulus et Uncus(l00mg/kg) was administered immediately after 2 hours of MCAO and maintained for 7 days. On 7th days after 2 hours of MCAO, the brains of rats were sliced through the hippocampus. c-Fos immunohistochemistry stain and Cresyl violet stain were done for microscopic examination. Each number of viable neurons and c-Fos immunoreactive cells in CA1 was counted. The density of neurons and c-Fos immunoreactive cells were significantly decreased in MCAO-operated ischemic rats compared to that sham-operated rats. Administration of Uncariae Ramulus et Uncus group significantly elevated MCAO-induced decrease in density of neurons, and elevated MCAO-induced decrease in c-Fos immunoreactive cells. These results suggest that the neuroprotective effect of Uncariae Ramulus et Uncus against focal cerebral ischemia. Also, we hypothesized that neuroprotective mechanism of Uncariae Ramulus et Uncus is related to IEGs expression.