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신종수,이문정,정현주,박준은 대한소아혈액종양학회 2014 Clinical Pediatric Hematology-Oncology Vol.21 No.1
Background: Hemoglobinopathy is inherited anemia characterized by abnormal structure of one of the globin chains of the hemoglobin molecule and has been known to be rare in Korea. However, hemoglobinopathy in children has been reported more frequently than in past with the recent advancement of molecular testing. The purpose of this study was to investigate the clinical and laboratory findings, prevalence and complications of hemoglobinopathy of children. Methods: Data of pediatric patients diagnosed with hemoglobinopathy from 2002 to February 2014 at Ajou University Hospital were surveyed. We analyzed patients’ characteristics from clinical and laboratory findings retrospectively. Results: Among a total of 10 children who were diagnosed with hemoglobinopathy, 9 patients were confirmed hemoglobinopathy by gene analysis. Eight patients had b thalassemia, 1 hemoglobin D disease, and 1 hemoglobin Koriyama. In most of the children, anemia was found incidentally and most of the children did not have symptoms. In the initial blood test, their mean hemoglobin concentration was 10.0 g/dL (range: 4.7-11.2 g/dL), mean corrected reticulocyte count was 3.9% (range: 0.9%-12.2%), and mean total bilirubin level was 1.0 mg/dL (range: 0.3-5.8 mg/dL). Conclusion: The analysis of clinical and laboratory features showed that the characteristics of each type of hemoglobinopathy were similar to that previously reported. We recommend considering hemoglobinopathy if pediatric patient presents with hemolytic anemia. A well organized diagnostic approach including molecular genetic analysis is needed for accurate diagnoses and appropriate management of hemoglobinopathy.
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신종수,안순일 한국기상학회 2018 Asia-Pacific Journal of Atmospheric Sciences Vol.54 No.1
Two leading but independent modes of Northern Pacific atmospheric circulation: the North Pacific Oscillation (NPO) and the Pacific Meridional Mode (PMM), are known external triggers of the El Niño-Southern Oscillation (ENSO) by the sequential migration of sea surface temperature (SST) anomalies into the tropics possibly by means of wind-evaporation-SST (WES) feedbacks. Because of the similar roles of NPO and PMM, most previous studies have explored them with no separation. Here, we investigate their independent and combined effects in triggering ENSO, and find that when the NPO and PMM occur simultaneously during spring, ENSO or ENSO-like SST anomalies are generated during the following winter; whereas when either the NPO or PMM occur alone, ENSO events rarely occur. Furthermore, the relationship between NPO and PMM shows noticeable interdecadal variability, which is related to decadal changes in the mean upper-level jet stream over the North Pacific. Changes in the upper-level jet stream modify the location of the center of the Aleutian Low, which plays a role in bridging the NPO and PMM processes, especially when it migrates to the southwest. The period when NPO and PMM are well correlated coincides somewhat with the active ENSO period, and vice versa, indicating that a more efficient trigger due to combined NPO-PMM processes results in a higher variation of ENSO. Finally, analysis of the coupled model control simulations strongly supports our observational analysis results.
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심한 방광 요관 역류를 동반한 양측성 Hutch's Diverticulum 1례
신종수,전유식,나창수,정건영,염규영,Shin Jong-Su,Jeon Yu-Sik,Ra Chang-Soo,Jeong Gun-Young,Yeum Gyu-Young 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.1
A bladder diverticulum occurs when the bladder mucosa herniates or protrudes through the muscular wall of the baldder. The majority of congenital bladder diverticula occurs in males. They are the most common in the region of the bladder base, most frequently in the region of the ureteral hiatus, in which case they are known as Hutch's diverticula. They can give rise to obstruction or reflux. We had experienced a case of bilateral Hutch's diverticulum associated with vesicoureterai reflux in a 23 month old male. Chief complaints were urinary frequency and dysuria. Voiding cystourogram and CT scan revealed large bilateral Hutch's diverticulum with bilateral vesiciureteral reflux grade VI. There was evidence of urinary infection. This patient was successfully treated by ureteroneocystostomy. We report this case with a brief review of related literatures.
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위팔두갈래근 힘줄염의 초음파 소견:위팔두갈래근 힘줄의 단면적 측정
신종수,유승민,서경묵,이화연,송인섭 대한초음파의학회 2009 ULTRASONOGRAPHY Vol.28 No.4
Purpose: The purpose of this study was to describe typical sonographic findings in patients with biceps tendinitis. Materials and Methods: Seventy five patients who had been clinically diagnosed with biceps tendinitis were included. Of the 75, 37 were male, 38 were female, and their mean age was 56 ± 9.74. The patients complained of shoulder pain and ultrasonography was performed for bilateral shoulders in all patients. The cross sectional area of the biceps tendon was measured. The status of fluid collection around the biceps tendon and accompanying rotator cuff disease were also investigated. Results: The cross sectional areas of the diseased biceps tendon were 0.18 ± 0.09 cm² (range: 0.07-0.42), and the areas of the normal side was 0.11 ± 0.05 cm² (0.03-0.24). The cross sectional area of the diseased biceps tendon was 0.075 ± 0.062 cm2 greater, on average, than the uninvolved site (p < 0.01). Thirty six patients (48%) had fluid collection around the inflamed biceps tendon, and 30 patients had accompanied rotator cuff disease. Conclusions: During US examination of the shoulder in patients complaining of shoulder pain, if the cross sectional area of the biceps tendon in the painful shoulder is asymmetrically and larger than the contralateral tendon, biceps tendonitis is suggested. 목적: 임상적으로 위팔두갈래근 힘줄염으로 진단된 환자에서 특징적인 초음파 소견에 대해서 알아보고자 한다. 대상 및 방법: 어깨 통증을 호소하여 임상적으로 위팔두갈래근 힘줄염으로 진단된 75명의 환자를 대상으로 하였다. 대상 환자의 나이는 평균 56 ± 9.74 세 이었고, 남자가 37명, 여자가 38명 이었다. 모든 환자에서 양쪽 위팔두갈래근 힘줄에 대하여 초음파 검사를 시행하였고, 각각의 단면적을 측정하였다. 또한 위팔두갈래근 힘줄 주변의 액 저류 동반여부와 회전근개 질환의 동반여부를 알아보았다. 결과: 위팔두갈래근 힘줄염으로 진단된 환자의 병측 위팔두갈래근 힘줄의 단면적은 평균 0.18 ± 0.09 cm2 (0.07-0.42)이었고, 정상측 위팔두갈래근 힘줄의 단면적은 평균 0.11 ± 0.05 cm² (0.03-0.24) 이었다. 각각의 환자에서 정상측 위팔 두갈래근 힘줄의 단면적에 비해 위팔두갈래근 힘줄염이 있는쪽의 힘줄의 단면적이 평균 0.075 ± 0.062 cm² 더 넓었다 (p< 0.01). 위팔두갈래근 힘줄염 환자에서 힘줄 주변의 액 저류를 동반한 환자는 36명(48%) 이었고, 회전근개의 질환을 동반한 환자는 30명(40%) 이었다. 결론: 어깨 통증을 호소하는 환자의 어깨 초음파 검사에서 양측 위팔두갈래근 힘줄의 단면적을 비교하여 통증을 호소하는 쪽의 위팔두갈래근 힘줄의 단면적이 반대쪽에 비해 더 넓을 경우 위팔두갈래근 힘줄염으로 진단할 수 있다.
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