Marginal fit of anterior 3-unit fixed partial zirconia restorations using different CAD/CAM systems

송태진,권택가,양재호,한중석,이재봉,김성훈,여인성 대한치과보철학회 2013 The Journal of Advanced Prosthodontics Vol.5 No.3

PURPOSE. Few studies have investigated the marginal accuracy of 3-unit zirconia fixed partial dentures (FPDs) fabricated by computer-aided design/computer-aided manufacturing (CAD/CAM) system. The purpose of this study was to compare the marginal fit of zirconia FPDs made using two CAD/CAM systems with that of metalceramic FPDs. MATERIALS AND METHODS. Artificial resin maxillary central and lateral incisors were prepared for 3-unit FPDs and fixed in yellow stone. This model was duplicated to epoxy resin die. On the resin die, 15 three-unit FPDs were fabricated per group (45 in total): Group A, zirconia 3-unit FPDs made with the Everest system; Group B, zirconia 3-unit FPDs made with the Lava system; and Group C, metal-ceramic 3-unit FPDs. They were cemented to resin dies with resin cement. After removal of pontic, each retainer was separated and observed under a microscope (Presize 440C). Marginal gaps of experimental groups were analyzed using oneway ANOVA and Duncan test. RESULTS. Mean marginal gaps of 3-unit FPDs were 60.46 μm for the Everest group, 78.71 μm for the Lava group, and 81.32 μm for the metal-ceramic group. The Everest group demonstrated significantly smaller marginal gap than the Lava and the metal-ceramic groups (P<.05). The marginal gap did not significantly differ between the Lava and the metal-ceramic groups (P>.05). CONCLUSION. The marginal gaps of anterior 3-unit zirconia FPD differed according to CAD/CAM systems, but still fell within clinically acceptable ranges compared with conventional metal-ceramic restoration.

Total Cerebral Small-Vessel Disease Score is Associated with Mortality during Follow-Up after Acute Ischemic Stroke

송태진,김진권,송동범,유준상,김용재,남효석,허지회,김영대 대한신경과학회 2017 Journal of Clinical Neurology Vol.13 No.2

Background and Purpose The recently developed total cerebral small-vessel disease (CSVD) score might appropriately reflect the total burden or severity of CSVD. We investigated whether the total CSVD score is associated with long-term outcomes during follow-up in patients with acute ischemic stroke. Methods In total, 1,096 consecutive patients with acute ischemic stroke who underwent brain magnetic resonance imaging were enrolled. We calculated the total CSVD score for each patient after determining the burden of cerebral microbleeds (CMBs), high-grade white-matter hyperintensities (HWHs), high-grade perivascular spaces (HPVSs), and asymptomatic lacunar infarctions (ALIs). We recorded the date and cause of death for all of the patients using data from the Korean National Statistical Office. We compared the long-term mortality rate with the total CSVD score using Cox proportional-hazards models. Results CMBs were found in 26.8% of the subjects (294/1,096), HWHs in 16.4% (180/1,096), HPVSs in 19.3% (211/1,096), and ALIs in 38.0% (416/1,096). After adjusting for age, sex, and variables that were significant at p<0.1 in the univariate analysis, the total CSVD score was independently associated with long-term death from all causes [hazard ratio (HR)=1.18 per point, 95% confidence interval (CI)=1.07–1.30], ischemic stroke (HR=1.20 per point, 95% CI=1.01–1.42), and hemorrhagic stroke (HR=2.05 per point, 95% CI=1.30–3.22), but not with fatal cardiovascular events (HR=1.17 per point, 95% CI=0.82–1.67). Conclusions The total CSVD score is a potential imaging biomarker for predicting mortality during follow-up in patients with acute ischemic stroke.

확장형심근병증과 뇌경색증을 동반한 듀센 근육이영양증 환자

송태진,조한나,이준범,이명준,서경임,김선정,최영철 대한신경과학회 2009 대한신경과학회지 Vol.27 No.1

갑상샘과다증을 동반한 임신 입덧 환자에서의 베르니케 뇌병증 1예

송태진,김도현,김원주,이경열 대한신경과학회 2006 대한신경과학회지 Vol.24 No.5

공압을 이용한 저가의 무인 잠수정 설계

송태진,정원지,권영수,손창우,서형덕,박우범,장성현,김명숙 한국정밀공학회 2003 한국정밀공학회 학술발표대회 논문집 Vol.2003 No.10월

뇌바닥동맥형성저하와 삼차동맥존속증을 동반한 외측 연수증후군 1예

송태진,김원주 대한뇌졸중학회 2009 Journal of stroke Vol.11 No.1

종양용해 단순포진 바이러스의 간암치료 적용 가능성에 대한 연구

송태진 대한외과학회 2005 대한외과학회 학술대회 초록집 Vol.2005 No.10

Characteristics of Elderly-Onset (≥65 years) Headache Diagnosed Using the International Classification of Headache Disorders, Third Edition Beta Version

송태진,김용재,김병건,김병수,김재문,김수경,문희수,차명진,박광열,손종희,주민경,조수진 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.4

Background and Purpose New-onset headache in elderly patients is generally suggestive of a high probability of secondary headache, and the subtypes of primary headache diagnoses are still unclear in the elderly. This study investigated the characteristics of headache with an older age at onset (≥65 years) and compared the characteristics between younger and older age groups. Methods We prospectively collected demographic and clinical data of 1,627 patients who first visited 11 tertiary hospitals in Korea due to headache between August 2014 and Febru¬ary 2015. Headache subtype was categorized according to the International Classification of Headache Disorders, Third Edition Beta Version. Results In total, 152 patients (9.3%, 106 women and 46 men) experienced headache that began from 65 years of age [elderly-onset group (EOG)], while the remaining 1,475 patients who first experienced headache before the age of 65 years were classified as the younger-age-at-onset group (YOG). Among the primary headache types, tension-type headache (55.6% vs. 28.8%) and other primary headache disorders (OPH, 31.0% vs. 17.3%) were more com¬mon in the EOG than in the YOG, while migraine was less frequent (13.5% vs. 52.2%) (p=0.001) in the EOG. Among OPH, primary stabbing headache (87.2%) was more frequent in the EOG than in the YOG (p=0.032). The pain was significantly less severe (p=0.026) and the frequency of medication overuse headache was higher in EOG than in YOG (23.5% vs. 7.6%, p=0.040). Conclusions Tension-type headache and OPH headaches, primarily stabbing headache, were more common in EOG patients than in YOG patients. The pain intensity, distribution of head¬ache diagnoses, and frequency of medication overuse differed according to the age at headache onset.

Rescue Treatment with Intra-arterial Tirofiban Infusion and Emergent Carotid Stenting

송태진,이기웅,김동준,이경열 연세대학교의과대학 2008 Yonsei medical journal Vol.49 No.5

Rapid arterial rethrombosis is associated with high-grade residual stenosis and usually occurs at the site of the initial occlusion, resulting in reocclusion of the recanalized artery. Platelets may play an active role in such rethrombosis after thrombolytic-induced clot lysis. Given that glycoprotein IIb/IIIa receptor blockers, like tirofiban, prevent thrombus formation by inhibiting the final common pathway of platelet aggregation, they may be helpful for treating rethrombosis after thrombolysis. A 64-year-old man presented with an acute ischemic stroke due to internal carotid artery (ICA) occlusion. The ICA was recanalized by intravenous thrombolysis but reoccluded shortly after recanalization. The reoccluded ICA was successfully recanalized using intra-arterial tirofiban. A carotid stent was subsequently inserted to relieve severe stenosis and to prevent recurrent stroke. Here, we report a case of rescue treatment of a successfully recanalized ICA by intra- arterial tirofiban. We suggest that rescue use of intra-arterial tirofiban may be effective and safe, especially in hemorrhage prone situations, due to the relatively lower dose of tirofiban compared with intravenous doses.

듀시엔형 근이영양증과 베커 근이영양증 환자의 심장 기능 평가

송태진,최영철 대한신경과학회 2007 대한신경과학회지 Vol.25 No.4

Background: Cardiac problems are common and are a major cause of death in both Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Early diagnosis and proper management are very important for prolonging life expectancy, improving mobility and the quality of life in dystrophinopathic patients. The object of this study was to assess the cardiac dysfunction in dystrophinopathic patients. Methods: We reviewed the clinical and laboratory findings of 53 male patients with DMD/BMD. The diagnosis was based on clinical criteria suggested by the European neuromuscular center, dystrophin gene analysis and immunohistochemistry of dystrophinopathic patients. We investigated 12-lead electrocardiography (EKG) findings, cardiac echocardiography findings and exon deletion analysis of dystrophin by multiplex polymerase chain reaction. Results: The mean age of 53 patients was 20.98±7.85 years old. On EKG findings of DMD/BMD patients, 50 patients (94.3%) revealed abnormal findings (DMD 36 [94.7%]/BMD 14 [93.3%]). Of the forty nine patients investigated by cardiac echocardiography, 25 patients (51.1%) showed abnormal echocardiographic findings (DMD 18 [51.4%]/BMD 7 [50.0%]), 18 patients (36.7%) had dilated cardiomyopathy, and 7 (14.3%) patients had cardiac symptoms (DMD 4 [11.4%] /BMD 3 [21.4%] numbers). There was no difference in the neurological disability score between normal echocardiographic finding patients and abnormal patients. On DNA analysis by multiplex PCR, the proximal exon deletion of dystrophin genes (exon 1-30) has a significant association with cardiac involvement compared to those of distal exon deletion (exon 31-60) (p=0.034). Conclusions: Because DMD/BMD patients mostly have affected cardiac dysfunctions without clinical symptoms, early diagnosis and appropriate management of asymptomatic cardiac dysfunctions is very important. J Korean Neurol Assoc 25(4):515-520, 2007