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서현성 ( Hyun Sung Seo ),김은영 ( Eun Young Kim ),박인서 ( In Suh Park ),박현선 ( Hyun Seon Park ),박형천 ( Hyung Chun Park ),박종운 ( Chong Oon Park ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2009 대한뇌종양학회지 Vol.8 No.2
Acute tumor-like demyelination or demyelinating pseudotumor is a variant presentation of demyelinating diseases, such as multiple sclerosis. A 32 years old male developing left side hemiparesis for 4 days and general tonic clonic seizure lasting 2 minutes was admitted to the hospital. Brain magnetic resonance imaging(MRI) taken at other hospital showed a large and irregular well enhancing intra-axial mass in right fronto-parietal area with massive surrounding edema. Craniotomy was planned under the impression of the malignant glioma. The edema and hemiparesis subside by preoperative use of corticosteroid. Therefore we had to rule out lymphoma. Stereotactic biopsy revealed a demyelinating lesion consistent with demyelinating pseudotumor. The patient recovered from hemiparesis by corticosteroid treatment over several weeks. The demyelinating pseudotumor, which usually presents as a well enhancing and poorly defined intra-axial lesion with edema, is very hard to distinguish from intra-axial tumors such as lymphoma and malignant glioma. Neurosurgeons should be aware of the possibility of demyelinating pseudotumor though it is rare.
Repeated Complication Following Atlantoaxial Fusion: A Case Report
오창현,지규열,서현성,윤승환,현동근,박형천 대한척추신경외과학회 2014 Neurospine Vol.11 No.1
A patients with atlantoaixial instability and osodontoideum underwent atlantoaixial fusion (Harms and Melcher technique) with demineralized bone matrix. But, unfortunately, the both pedicle screws in C2 were fractured within 9 weeks follow-up periods after several suspected episode of neck hyper-flexion. Fractured screws were not contact to occipital bone in several imaging studies, but it could irritate the occipital bone when neck extension because the relatively close distance between the occipital bone and C1 posterior arch. The patient underwent revision operation with translaminar screw fixation with autologus iliac bone graft. Postsurgical course were uneventful except donor site pain, but the bony fusion was not satisfied after 4 months follow-up. The patient re-underwent revision operation in other hospital. Continuous complication after atlantoaixial fusion is rare, but the clinical course could be unlucky to patients. Postoperative immobilization could be important to prevent the unintended clinical course of patients.
권장훈(Jang Hoon Kwon),서현성(Hyun Sung Seo),장해인(Hae In Jang),조형민(Hyoung Min Cho),김은영(Eun Young Kim),김경심(Kyoung Sim Kim),김용욱(Yong Wook Kim),김 령(Young Kim) 조선대학교 의학연구원 2023 The Medical Journal of Chosun University Vol.48 No.2
Inflammatory bowel disease (IBD), comprised of two major disorders, Crohn disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders that can affect the gastrointestinal tract. It is known that IBD commonly presents with extraintestinal manifestations (EIMs). Children and adolescents with IBD are often at risk for suboptimal bone health because of undernutrition, delayed puberty, and prolonged glucocorticoid (GC) use. The authors report a case of a child with IBD and osteolysis in this report.
아미노산 분유로 변경 후 병증이 호전되어 우유 단백 유발 알러지로 진단된 신생아 4예
김현종(Hyun Jong Kim),유명환(Myung Hwan Yoo),서현성(Hyun Sung Seo),장해인(Hae In Jang),조형민(Hyoung Min Cho),김은영(Eun Young Kim),김경심(Kyoung Sim Kim),김용욱(Yong Wook Kim),김령(Young Kim) 조선대학교 의학연구원 2023 The Medical Journal of Chosun University Vol.48 No.1
Cow’s milk protein allergy(CMPA) or cow’s milk protein-induced allergy is the most common food allergy in children. It has been reported to have a 2 to 3% prevalence in infants within one year of age, but the exact prevalence in newborns within one month of age has not yet been accurately reported. In children who have non-specific symptoms such as diarrhea, bloody stool, vomiting, and urticaria within a few weeks of exposure to milk protein, if the symptoms improve when changing to a diet without milk protein, a milk allergy can be diagnosed without additional tests. The extensively hydrolyzed formula is generally recommended first as a diet with milk protein eliminated, but amino acid-based formula can be considered preferentially as milk allergy may recur due to residual immunologically active proteins in the extensively hydrolyzed formula. In this report, the authors report four cases of newborns diagnosed with CMPA after changing to amino acid-based formula.