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이건섭,서민호,백성덕 대구보건대학 1994 대구보건대학 論文集 Vol.14 No.-
The development of recombinant DNA technology bring about a revolution in biology. In medicine molecular biology is widely appolicated to diagnosis, treatment and understanding of disease. For diagnosis of infectious disease, cancer and genetic disorder, recombinant DNA technology provides rapid, specific, sensitive new method ; Southern blot, Northern blot, in situ hybridization and PCR(Polymerase Chain Reaction), etc. PCR is being used for rapid and sensitive diagnostic method of infectious disease, for example for diagnosis fo Mycobacterium tuberculosis classic culture method needs 4~7 weeks but PCR only 1~2 days. Over the nest few years by combing automated method for DNA extraction, PCR, and non-radioactive labelling, it may be possible to automate most of steps in molecular diagnosis of disease.
백성덕 ( S D Paik ),서민호 ( M H Sub ),이건섭 ( G S Lee ) 대한임상검사과학회 1992 대한임상검사과학회지(KJCLS) Vol.24 No.1
The development of recombinant DNA technology bring about a revolution in biology. In medicine molecular biology is widely appolicated to diagnosis, treatment and understanding of disease. For diagnosis of infectious disease, cancer and genetic disorder, recombinant DNA technology provide.:; rapid, specific, sensitive new method ; Southern blot, Northern blot, in situ hybridization and PCR(Polymerase Chain Reaction), etc. PCR is being used for rapid and sensitive diagnostic method of infectious disease, for example for diagnosis fo Mycobacterium tuberculosis classic culture method needs 4 --7 weeks but PCR only 1-- 2 days. Over the next few years by combing automated method for DNA extraction, PCR, and non-radioactive labelling, it may be possible to automate most of steps in molecular diagnosis of disease.