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Prenatal diagnosis of Trisomy 7 with Omphalocele in the First Trimester of Pregnancy (초)
박지은 ( Ji Eun Park ),( Eun Ju Kim ),( Dong Hui Lee ),( Min Kyung Ko ),( In Ae Cho ),( Jee Hae Cho ),( Young Park ),( Man Taek Ha ),( Ji Kwon Park ),( Jeong Kyu Shin ),( Won Jun Choi ),( Soon Ae Lee ),( 대한산부인과학회 2010 대한산부인과학회 학술대회 Vol.96 No.-
정부에 대한 신뢰도와 광우병 리스크 인식과의 관련성 연구
박지은 ( Jee Eun Park ),손애리 ( Ae Ree Sohn ) 대한보건협회 2010 대한보건연구 Vol.36 No.2
Objectives: The purpose of this study was to identify the relationship between government trust and risk perception of Mad Cow Disease (MCD). Methods: This study design was cross-sectional study using self-administerd questionnaire. The survey subjects were mothers of elementary school students in Seoul, total of 642 subjects. The survey period was from December 7 through December 18 of 2009, and the collected data were analyzed using the SPSS 12.0. Results: The subjects perceived high risk of the MCD. About 80.8% of the subjects perceived that the result of MCD was fatal, 74.9% agreed that the MCD was a new type of threat, 69.0 percent agreed that the MCD was a very dreadful disease. The risk perception of the MCD was related to government trust factors, especially government policy. Those who did not believe that the current government policy was correct and government was working toward the public`s benefit and not its own had the higher level of risk perception of the MCD. Conclusion: In implementing government policy, all information should be efficiently and accurately communicated through a transparent implementation process. Also, the government must have plans for countermeasures in case of an emergency and respond efficiently in order to maintain their credibility. The understanding of the differences between the experts` and the public`s risk communication should be considered. For more effective risk communication, media, health experts, government representatives, and related industries should work together.
박지은(Jie-Eun Park),이성학(Sung-Hak Lee),최재묵(Jae-Mook Choi),김일환(Il-Hwan Kim),김덕열(Deog-Yeor Kim),노현정(Hyun-Jung Noh),김택로(Taekrho Kim),김영훈(Young-Hoon Kim),임지웅(Lim Jee Woong),김진완(Jin-Wan Kim),장준환(Jun-Hwan Chan 한국독성학회 2004 Toxicological Research Vol.20 No.1
To evaluate the genotoxicity of CJ-11555, an anti-cirrhotic agent, the reverse mutation test, chromosomal aberration test and in vivo micronucleus test in rats were performed. In the reverse mutation test, the treatment of CJ-11555 at doses of 33.3, 100, 333, 1000, 3330 and 5000 mg/plate with and without S9 did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA1537, and Escherichia coli ( E. coli) WP2 uvrA. In chromosomal aberration test, CJ-11555 did not induce structural a chromosomal aberration in Chinese hamster ovary (CHO) cells with and without metabolic activation at all doses. In micronucleus test, CJ-11555 did not induce any statistically significant increases in micronucleated polychromatic erythrocyte (MNPCE) at doses of 500, 1000, and 2000 mg/kg. These results suggest that CJ-11555 might not have a mutagenic potential under the conditions in this study.
박지은(Jie-Eun Park),이성학(Sung-Hak Lee),최재묵(Jae-Mook Choi),김일환(Il-Hwan Kim),김덕열(Deog-Yeor Kim),노현정(Hyun-Jung Noh),김택로(Taekrho Kim),김영훈(Young-Hoon Kim),임지웅(Lim Jee Woong),김진환(Jin-Wan Kim),장준환(Jun-Hwan Chan 한국독성학회 2004 Toxicological Research Vol.20 No.2
To evaluate the genotoxicity of CJ-11555, an anti-cirrhotic agent, the reverse mutation test, chromosomal aberration test and in vivo micronucleus test in rats were performed. In the reverse mutation test, the treatment of CJ-11555 at doses of 33.3, 100, 333, 1000, 3330 and 5000 mg/plate with and without S9 did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA1537, and Escherichia coli ( E. coli) WP2 uvrA. In chromosomal aberration test, CJ-11555 did not induce structural a chromosomal aberration in Chinese hamster ovary (CHO) cells with and without metabolic activation at all doses. In micronucleus test, CJ-11555 did not induce any statistically significant increases in micronucleated polychromatic erythrocyte (MNPCE) at doses of 500, 1000, and<br/> 2000 mg/kg. These results suggest that CJ-11555 might not have a mutagenic potential under the conditions in this study.
대도시 중심부 쪽방촌 주민의 알코올 사용 장애 유병률과 작업상실일
손지훈(Jee Hoon Sohn),조성준(Sung Joon Cho),안성희(Seung-Hee Ahn),성수정(Su Jeong Sung),유지민(Ji Min Ryu),박지은(Ji Eun Park),조맹제(Maeng Je Cho) 대한사회정신의학회 2016 사회정신의학 Vol.21 No.2
연구목적 : 본 연구는 대도시 중심부 쪽방촌 주민의 알코올 사용 장애 유병률과 작업상실일(Work-loss day)을 평가하여 해당 인구의 알코올 관련 문제의 기능 손실 기여도를 보고자 하였다. 방 법 : 서울 중심권역인 창신동과 돈의동의 쪽방 밀집 지역의 주민에 대하여 정신보건센터를 중심으로 구청 및 지역 내 관련기관의 협력을 받아 한국어판 Composite International Diagnostic Interview(K-CIDI)와 World Health Organization Disability Assessment Schedule II(WHODAS-II)를 포함한 조사를 실시하였다. 가가호호 직접 방문하여 해당지역의 전수 조사를 목표로 하였으며, 969명의 대상자 중 581명이 마무리를 하였다. 결 과 : 알코올 의존과 남용에 대한 평생 유병률은 각각 24.8%, 10.2%였으며, 1년 유병률은 각각 18.4%와 5.3%로 조사되었다. 알코올 의존에 대한 주요 위험인자로는 남성, 60세 이하의 나이, 노숙의 경험, 알코올 문제의 가족력과 우울증상 등이 유의한 결과를 보였다. 1년내 알코올 의존을 보인 군에서는 31%의 작업상실일(Work-loss day)이 관찰되었으며, 여러 변수를 보정한 분석에서 알코올 사용 장애가 독립적으로 초래하는 작업상실률%는 6.66%였다. 외에도 우울증상, 만성 질환, 등급을 받은 장애의 여부 등은 유의한 수준의 작업상실일지수%의 예측인자로, 현재 고용 상태는 보호요인으로 관찰되었으며, 그 기여도는 알코올 의존보다 큰 것으로 조사되었다. 결 론 : 조사가 진행된 쪽방촌 지역은 알코올 사용 장애 문제 유병률이 높았으며, 작업상실일 및 작업상실률% 또한 유의한 수준으로 관찰되었다. 하지만, 이에 대한 기여도는 우울증상, 만성 질환, 등급을 받은 장애의 여부 등이 알코올 의존보다 높았다. 그러므로 알코올 사용 장애가 언급된 요인들의 결과일 수도 있겠다. Objective : The aim of this study was to estimate the prevalence of alcohol use disorder and its effect on work-loss days among the people living in Single-Room-Occupancy (SRO) areas of central Seoul. Methods : Door to door household survey was conducted with all single-room-occupants in the study area. Of 969 people living in the area, 581 subjects completed interview with Korean Version of Composite International Diagnostic Interview as well as WHO disability assessment schedule-II. Results : Lifetime prevalence of alcohol dependence was 24.8% and alcohol abuse was 10.2%. One year prevalence of alcohol dependence was 18.4% and alcohol abuse was 5.3%. Main risk factors of alcohol dependence were male gender, younger age than 60 years, experience of homelessness, family history of alcoholism and depressive symptoms. People with alcohol dependence showed monthly work-loss of 31%. But only 6.7 percentage points of work-loss could be directly attributed to the alcohol dependence. Employments status, registered disability, chronic health problem and depressive symptom were stronger predictors of work-loss days (%) than alcohol dependency. Conclusion : Alcohol use problem was highly prevalent in single-room occupant areas with significant loss of work-days. But depressive symptoms, unemployment and physical health account for more work-loss days than alcohol dependence, and it might be possible that alcohol use disorders being the result of those factors.