Obesity Phenotype and Coronary Heart Disease Risk as Estimated by the Framingham Risk Score

박용순,김준수 대한의학회 2012 Journal of Korean medical science Vol.27 No.3

There are conflicting data as to whether general or abdominal obesity is a better predictor of cardiovascular risk. This cross-sectional study involved 4,573 subjects aged 30 to 74 yr who participated in the Fourth Korea National Health and Nutrition Examination Survey conducted in 2008. Obesity phenotype was classified by means of body mass index (BMI) and waist circumference (WC), and participants were categorized into 4 groups. Individuals’ 10-yr risk of coronary heart diseases (CHD) was determined from the Framingham risk score. Subjects with obese WC had a higher proportion of high risk for CHD compared to the normal WC group, irrespective of BMI level. Relative to subjects with normal BMI/normal WC, the adjusted odds ratios (ORs) of normal BMI/obese WC group (OR 2.93 [1.70, 5.04] and OR 3.10 [1.49, 6.46]) for CHD risk in male were higher than obese BMI/obese WC group (OR 1.91 [1.40, 2.61] and OR 1.70 [1.16, 2.47]), whereas the adjusted ORs of obese BMI/obese WC group (OR 1.94 [1.24, 3.04] and OR 3.92 [1.75, 8.78]) were higher than the others in female. Subjects with obese BMI/normal WC were not significantly associated with 10-yr CHD risk in men (P = 0.449 and P = 0.067) and women (P = 0.702 and P = 0.658). WC is associated with increased CHD risk regardless of the level of BMI. Men with normal BMI and obese WC tend to be associated with CHD risk than those with obese BMI and obese WC.

심혈관계질환의 위험지표로서Omega-3 Index에 대한 올바른 이해 및 한국인에의 적용

박용순 대한비만학회 2010 The Korean journal of obesity Vol.19 No.1

오메가-3 다가 불포화지방산인 eicosapentaenoic acid(EPA; C20:5)와 docosahexaenoic acid(DHA; C22:6)는 심혈관계질환으로 인한 사망을 예방하는 영양소로 잘 알려져 있다. 최근에는 오메가-3 지방산이 심혈관계질환뿐 아니라 뇌졸중을 예방하는데도 도움이 된다는 연구결과가 보고되고 있으며, 이러한 오메가-3 지방산의 효과는 항부정맥, 항염증, 혈액응고 억제, 지단백질 농도 저하 등과 관련이 있다고 한다. Omega-3 Index는 오메가-3 지방산의 체내 수준을 나타내는 유일한 표준 혈액 검사로 적혈구의 EPA와 DHA 수준을 의미한다. Omega-3 Index는 섭취한 오메가-3 지방산과 비례할 뿐 아니라, 심장근육의 오메가-3 지방산 농도와도 비례함하고, 심혈관계질환의 위험도와 음의 상관관계를 가진다고 알려져 심혈관계질환의 위험지표로 활용되고 있다. 권장섭취량인 1g의 오메가-3 지방산으로 얻을 수 있는 8-10% Omega-3 Index가 심혈관계질환의 예방을 위한 적정 목표치로 설정되었다. 한국인에게도 Omega-3 Index는 활용가능하나 목표치는 상향 조정이 필요하다고 사료된다. Of all known dietary factors, long-chain omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) may be the most protective against death from cardiovascular disease. Evidence continues to accrue for benefits of omega-3 fatty acids in the prevention of coronary heart disease and stroke. Anti-arrhythmogenic, anti-inflammatory, anti-thrombotic and hypolipidemic effects of omega-3-fatty acids are emerging as the most likely explanation. New evidence has confirmed and refined the cardioprotective risk factor of Omega-3 Index, the only standardized blood test of omega-3 fatty acids measuring content of erythrocyte eicosapentaenoic and docosahexaenoic acids. Current evidence suggests that individuals with coronary artery disease may reduce their risk of sudden cardiac death by increasing their intake of long-chain omega-3 fatty acids by approximately 1 g per day and achieving a target range of 8-10% Omega-3 Index. However, target range of Omega-3 Index for Koreans may be higher than 10%.

결혼이주여성의 문화적응 스트레스와 결혼만족도에 관한 연구: 자아존중감의 매개효과를 중심으로

박용순,송진영,이순자 성결대학교 다문화평화연구소 2012 다문화와 평화 Vol.6 No.2

The objective of this study was to verify the mediating effect of self-esteem on the relationship between acculturative stress and martial satisfaction of immigrant woman who married to Korean man. To achieve the goal, 174 immigrant women by conducting a questionnaire were selected as valid samples. SPSS 18.0 for technical statistics and the regression analysis was performed. The results of the study are: Firstly, self-esteem positively mediated between acculturative stress and martial satisfaction. Secondly, a woman`s job negatively effected and the difference of spouse information after marriage positively effected on martial satisfaction. Thirdly, communication and hostility problem among acculturative stress presented as the most information factor. Based on this results, this study suggested a practical intervention plan and policy were able to improve recognition and expropriation for martial satisfaction of married migrant women regarding a multicultural society for improving their self-esteem.

Facilitated transport of olefin through solid PAAm and PAAm-graft composite membranes with silver ions

박용순,원종욱,강용수 한국고분자학회 2000 한국고분자학회 학술대회 연구논문 초록집 Vol.2000 No.4

Preparation of Monolayer Star PEO Film on Poly(dimethylsiloxane) and Its Application to Facilitated Olefin Transport

박용순,운종옥,강용수 한국고분자학회 2000 한국고분자학회 학술대회 연구논문 초록집 Vol.2000 No.10

제2족지 수질부 유리피판을 이용한 수지첨부재건 치험례

박용순,홍종원,김영석,노태석,나동균,Park, Yong-Sun,Hong, Jong-Won,Kim, Young-Suk,Roh, Tai-Suk,Rah, Dong-Kyun The Korean Society for Microsurgery 2010 Archives of reconstructive microsurgery Vol.19 No.1

Purpose: First introduced by Buncke and Rose in 1979, the neurovascular partial $2^{nd}$ toe pulp free tissue transfer has been attempted to reconstruct posttraumatic finger tip injuries. Although some surgeons prefer other reconstructive methods such as skin graft and local flap, we chose the partial $2^{nd}$ toe pulp flap owing to its many advantages. We report three successful surgical cases in which the patients had undergone this particular method of reconstruction. Methods: We retrospectively examined three cases of fingertip injury patients due to mechanical injury. Bone exposure was seen in all three cases, All had undergone partial toe pulp free flap for soft tissue defect coverage. Results: All flaps survived without any complications such as partial necrosis, hematoma or dehiscence. Although tingling sensation has returned in both cases, two-point discrimination has not returned yet. Currently no patient is complaining of any pain which gradually improved during their course of recuperation. All stitches were removed on postoperative 2 weeks. Patients are satisfied with the final surgical result and there are no signs of any edema or hematoma. Conclusion: The homodigital reconstruction of finger tip injury using the partial $2^{nd}$ toe pulp flap has numerous advantages compared to other reconstructive modalities such as its resistance to wear and tear and in that it provides a non-slip palmar digital surface. However it requires microsurgery which may not be preferred by surgeons. Advanced age of the patient can be a relative contraindication to this approach since atheromatous plaque from the donor toe can compromise flap circulation after surgery. We report three successful cases which patient age was considered appropriate. Further investigation with a larger number of cases and long term follow-up is deemed necessary.

바이너리 코드를 이용한 Transformer기반 함수명 예측

김현진(HyunJin Kim),박진영(JinYeong Bak) 한국정보과학회 2021 한국정보과학회 학술발표논문집 Vol.2021 No.12

지방산섭취와 고혈압 위험요인과의 관련성

박용순,박효진,원선임 동아시아식생활학회 2016 동아시아식생활학회 학술발표대회논문집 Vol.2016 No.10

Poly(aspartic acid)를 이용한 조직공학용 지지체의 제조 및 특성

박용순 광주보건대학 2004 論文集 Vol.29 No.-

One of the most important properties of synthetic materials for biomedical applictions is that the materials should have biostability, biocompatibility and biodegadability. Polypeptides which were made of amino acid is useful to biomedical application because they are structural materials of biosystem. Poly(aspartic acid) (PAsp) is synthesized by polymerization of the corresponding N-carboxyamino acid anhydride (NCA)in solution in the presence of suitable catalysts. However, the NCA method have a production problem and a cost disadvantage. Recently, a simple method that the high molecular weight PAsp was easily synthesized by the polycondensation of L-aspartic acid in the presence of acid catalyst was developed. In this study, PAsp hydrogels have been prepared by the cross-linking reaction of PAsp produced by thermal polycondensation reactions with an acid catalyst. The molecular weight of synthesized PAsp was about 50,000(M_(W), DP = 500). And the PAsp hydrogels were formed when the the amount of cross-linker, i.e., ethylene diamine was above 10 mol%, The water absorption capacity of the PAsp hydrogel in deionized water was measured. The maximum water absorption capacity in deionized water was 1,400%. The PAsp hydrogels formed the interconnected porous stucture(pore size was about 100~200 ㎛) by scanning electron microscopy observation. The cytotoxicity test was carried out on the PAsp hydrogel using the fibroblast cells. After four days the fibroblast cells adhered and spread well on the PAsp hydrogel. Futhermore, the fibroblast cells proliferated well on the PAsp hydrogel compared with the normally cultured cells on the cell culture plate. These results are indicated that the PAsp hydrogels can be used as the scaffold for tissue engineering applications.

Validation of a New Food Frequency Questionnaire for Assessment of Calcium and Vitamin D Intake in Korean Women

박용순,김상희,임용택,하용찬,장재석,김이석,민용기,정호연 대한골대사학회 2013 대한골대사학회지 Vol.20 No.2

Background: Validated simple calcium questionnaires are available to assess the intake of calcium and vitamin D in western countries, but they are not appropriate for Koreans since dairy products are not the major source of calcium and vitamin D in Korea. Thus,the objective of the present study was to develop and validate a simple and easy food frequency questionnaire (FFQ) of calcium and vitamin D for Korean. Methods: Two hun -dred and fifty-six women were asked to complete the validated FFQ used by the Korean National Health and Nutrition Examination Survey (KNHANES) and a newly developed FFQ, the Korean Calcium Assessment Tool (KCAT), which contain the 7 food groups with 24 categories of 45 food items that are consumed frequently by Koreans. Results: Calci -um intake was not significantly different between the two methods; Pearson’s correla-tion coefficient of 0.98 indicated a positive correlation, and Cohen’s kappa coefficient of 0.78 indicated the subjects were correctly classified. Bland-Altman plot also showed that the mean differences of the calcium intake as assessed by the two methods were in high agreement. However, the vitamin D intake assessed by KCAT was significantly higher than that assessed by the FFQ used in KNHANES. The vitamin D intakes as assessed by the two methods were positively correlated but the two methods were in moderate agreement. Conclusions: The results suggested that the newly developed KCAT was a valid tool for assessing the calcium intake in Korean women, but it might overestimate the vitamin D intake.