위내시경으로 진단된 Gastric Red Spots ( GRS ) 의 병태생리 및 임상적 의의

이종철,양석철,성인경,강인구,함준수,이민호,기춘석,박경남,조석신 ( Jong Chul Rhee,Suk Chul Yang,In Kyung Seong,In Koo Kang,Joon Soo Hahm,Min Ho Lee,Choon Suck Kee,Kyung Nam Park,Suk Shin Cho ) 대한소화기학회 1992 대한소화기학회지 Vol.24 No.5

The incidence of GRS in the proximal part of the stomach was investigated in patients with various liver diseases. 477 patients with biopsy proven chronic liver disease underwent endoscopic study and GRS were obaerved in 38 (20.3%) out of 187 patients with liver cirrhosis, in 21 (16.8%) out of l25 patients with chronic active hepatitis, in 9 (15. 5%) out of 58 patients with chronic persietent hepatitis, and in 12 (14.3%) out of 84 patients with other chronic liver pathologies. There were no statistical differences among the groups. The incidence of chronic liver disease among patients with normal liver function tests and abdominal ultrasonography, but exhibiting GRS upon endoscopic study, was also prospectively studied by liver biopsy. 11 of 23 such patients had chronic liver disease: 2 had liver cirrhosis, 3 with chronic persistent hepatitis, and 6 with chronic reactive hepatitis, while 12 patients with no conclusive pathology in liver biopsy in spite of minimal disarray of hepatic lobular architecture and mild inflammatory cell infiltration into periportal area. The heart to liver radioisotope uptake ratios measured by Thallium-201 scan to estimate the portal pressure were 13+3% (mean+ SD) in 15 control subjects, 22+7% in 20 patients with chronic persistent hepatitis, 28+13% in 15 patients with chronic active hepatitis, 59+41% in 18 patients with liver cirrhosis, and 27+14% in 50 patients with GRS, but with normal liver function test results and normal abdomial ultrasonography. These results showed statistical difference from normal control (p<0.05). It can thus be concluded that GRS in the proximal part of the stomach could be a stigma of chronic liver disease, and would also indicate the presence of high portal pressure.

심포지움 : 대장의 운동성 질환

이종철 ( Jong Chul Rhee ) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.2

독자 편지 : 답변

이종철(Jong Chul Rhee) 대한소화기학회 2002 대한소화기학회지 Vol.39 No.2

N/A

경제성장-분배-빈곤의 삼중적 인과관계

이종철(Rhee Jong Chul) 한국동서경제학회 2004 한국동서경제연구 Vol.16 No.1

본 논문은 어떻게 하면 ”풍요속의 빈곤”을 불식시키면서 지속적인 성장을 해나갈 수 있을까 하는 주제의식에서 출발하였다. 이와 관련하여 기존의 이론적, 실증적 연구결과들을 체계적으로 고찰하고 논의를 발전시켜 다음과 같은 소결론들을 도출하였다. 첫째, 경제성장은 빈곤 해소의 일차적인 요인으로서 필요조건이지만 충분조건 은 아니라는 것, 둘째, 부의 불균등한 분배 상태는 경제성장을 더디게 할 뿐만 아니 라 경채성장의 빈곤 해소 효과를 떨어뜨린다는 것, 셋째, 경제성장을 저해하지 않는 부의 재분배 정책이 필요하다는 것, 넷째, 저속성장을 위해서는 인적자본의 축 적이 필수적이라는 것 등이다. 여와 같은 결론에 기초하여 정책적으로는 토지가치 세제가 검토되었다. 토지가치세제는 경제적 불평등이 초래되는 자본주의적 시장경제 에서 분배적 정의를 실현하며 바람직한 지속성장을 가능하게 하는 방책이다. 이는 또한 정채성장 과정에서 대두되는 토지 및 부동산 투기를 불식시키고 부의 불균등 문제를 해소할 수 있는 가능한 방안이다. 인적자본이 생산양식의 중심요소가 되어져 가고 기술진보의 원천이 되는 경제사회에서 교육투자는 지속적 경제성장의 필수 조건이며, 저소득 계층에 대한 교육기회 확대와 직‘간접적인 교육지원은 장기적으로 소득분배의 불균등 문재와 빈곤의 문제를 해소시키는 효과를 나타낸다. The purpose of this study is to find out how to overcome the problem of ""Poverty amongst Affluence"", keeping the economy on a sustainable growth path. Reviewing the related literature and extending discussion of connected topics, a few findings have emerged on which there seems to get broad consensus. First, economic growth is the primary factor and necessary condition for poverty reduction, but mere acceleration of growth is not enough for effective poverty reduction. Second, wealth inequality hinders economic growth, and decelerate poverty reduction for given rates of growth as well. Third, to achieve the goal of rapidly reducing poverty requires strong combinations of growth and redistribution policy. Fourth, investment in human capital is the foundation for sustainable growth, and mitigating wealth inequality increases investment in human capital. The Land Value Taxation is proposed for overcoming the problem of ""Poverty amongst Affluence"", keeping the economy on a sound growth.

우린라 성인 건강 검진자에서 배변습관에 관한 연구

이풍렬(Poong Lyul Rhee),이종철(Jong Chul Rhee),최규완(Kyoo Wan Choi),김은주(Eun Joo Kim),박창영(Chang Young Park),손정일(Jong Chul Rhee),전우규(Woo Kyu Cheon),김병익(Byeong Ik Kim),정을순(Eul Sun Jung),전성국(Seong Gook Cheon),박기호 대한내과학회 1999 대한내과학회지 Vol.57 No.1

To estimate bowel patterns in the Korean, we surveyed routine check-up subjects about their bowel habits, using self-reported questionnaire. Methods : We analyzed 2939 subjects (male 1430, female 1509; age range 25 - 65 years) who had visited health promotion center for routine check-up. Subjects were given a validated self-report questionnaire, which measured the defecation frequency; stool consistency; self-report of constipation; straining to defecate; and levels of laxative use. Results : Of the whole subjects 96.4% had defecation frequency between three per week and three per day. The prevalence of two or less bowel movements per week (4.1% compared to 0.6%), straining to defecate (20.8% compared to 13.0%) and hard stool (18.0% compared to 9.3%) was higher in women than men (p<0.01). The prevalence of self-reported constipation was higher in women than men (9.0% compared to 2.9%, p<0.01). Women were more likely to use laxatives than men (5.5% compared to 0.6%, p<0.01). Conclusions : Defecation frequency in most of routine check-up subjects is between three per week to three per day. Bowel dysfunction is a greater problem in women.

단일한 간종괴로 발현된 간질증

이종철(Jong Chul Lee),백승운(Seung Woon Paik),김재준(Jae Jun Kim),고광철(Kwang Cheol Koh),고영혜(Young Hyeh Ko),이화영(Hwa Young Lee),김춘관(Choon Kwan Kim),이풍렬(Poong Lyul Rhee),오영륜(Young Lyun Oh) 대한소화기학회 1997 대한소화기학회지 Vol.30 No.5

Fascioliasis, infection of fasciola sp., is a zoonotic liver disease in human which usually involves the liver and biliary tract. Its occurrence is common in tropical area, western America and in the Mediterranean region, but relatively uncommon in Korea. Fascioliasis is usually presented as multiple small liver abscess and it is extremly uncommon as a single large liver mass. We experienced a case of facioliasis. In an asytnptomatic 43 year-old woman, appearing as a single, large hepatic mass. Imaging study suggested that the rnass is likely to be a hetnangioma, hepatoma or metastatic lesion. We carried out fine needle aspiration of the liver, and its cytology showed only some Fasciola sp. egg. Patients serology to the parasite wasnt available at that time, so we carried out partial hepatic lobectomy to confirm the diagnosis of fascioliasis. We found a parasite granuloma, mummified adult worm of fasciola sp. (Korean J Gastroenterol 1997; 30: 689-694)

만성 간질환 환자에서 상부위장관 증상을 수반한 위내용물 배출시간 지연에 대한 Cisapride 치료 효과에 관한 연구

강인구,이종철 ( In Koo Kang,Jong Chul Rhee ) 대한소화기학회 1992 대한소화기학회지 Vol.24 No.5

It was documented in our previous studies that chronic hepatitis patients with disfunctional upper gastrointestinal symptoms were delayed in their gastric emptying than normal control group. Sixteen patients with chronic hepatitis participated in our clinical trial to assess the effect of cisapride on gastric emptying atd dysfunctional upper gastrointestinal symptoms such as recurrent nausea, vomiting, poatprandial fullness, anorexia, weight loss and something like that. They were each given cisapride 5 mg t.i.d. for 2 to 3 months. The results were as following: The patients with chronic liver disease with delayed GET participated in our study were 16 in number composed of ehronic active hepatitis 2, chronic persistent hepatitis 13, early liver cirrhosis 1, The GET of 16 patients with chronic liver disease was dealyed significantly in comparison with that of the normal control group (160+63. 3 vs 89.4+5.9; p<0.05). Follow-up GET of these patients after cisapride administration was 114. 1 + 34. 4 minutes and it was statistically different from initial GET. Cisapride also significantly improved dysfunctional gastrointestinal symptoms (6.82+2.56 vs 2.75+2.41; p<0.05). Only one side effect observed during cisapride treatment was skin rash with itching sensation but it disappeared soon after stop of the medication. No other significant side effects were noted.

15 위, 대장 내시경검사에서 원인을 찾지못한 위장관 출혈환자에 대한 임상고찰

김종형 ( Jong Hyung Kim ),김영호 ( Young Ho Kim ),손희정 ( Hee Jung Son ),이풍렬 ( Poong Lyul Rhee ),김재준 ( Jae Jun Kim ),이종철 ( Jong Chul Rhee ) 대한소화기학회 2002 대한소화기학회 추계학술대회 Vol.2002 No.-

담관 폐쇄 환자에서 담도압 상승과 관련이 있는 임상 지표

이종균(Jong Kyun Lee),이풍렬(Poong Lyul Rhee),김재준(Jae Jun Kim),고광철(Kwang Cheol Koh),백승운(Seung Woon Paik),이종철(Jong Chul Rhee),주성욱(Seong Wook Choo),주인욱(In Wook Choo) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.3

Background/Aims: Increased bile duct pressure is the major factor responsible for acute cholangi- tis and bacteremia. Therefore, prompt medical or surgical decompression of bile under high pressure should be accomplished as fast as possible. But, measuretnent of bile duct pressure is invasive. So, the present study was undertaken to find out the clinical factors to predict the increased biliary pressure in patients with bile duct obstruction. Methods: Thirty-three patients with bile duct obstruction underwent percutaneous transhepatic biliary drainage(PTBD). Intraductal pressure was measured as soon as bile duct pucture was performed. Bile cultures were performed in 24 patients and blood cultures were performed in 21 patients. Correlation of bile duct pressure and severity of pain, duration of symptom, fever, leukocytosis, serum bilirubin, serurn alkaline phosphatase, or bile duct diameter were statistically analyzed. Results: Bacteremias were noticed in 5 of the 17 patients with positive bile culture. Bacteremia was associated with the increased biliary pressure. Bacteremia was demonstrated when the biliary pressure was 22 cmHyO or more. Biliary pressure was associated with the severity of pain and body temperature. Significant correla- tion was not found between the duration of symptom, leukocytosis, serum bilirubin, serum alkaline phosphatase, or bile duct diameter and biliary pressure. Conclusions: Increased biliary pressure in patients with bile duct obstruction is more likely to be associated with severity of pain and fever than leukocytosis, bilirubin level, alkaline phosphatase level, or bile duct diameter. (Korean J Gastroenterol 1996; 28:409 - 414)

특발성 위무력증 환자군의 혈청 Gastrin 동태에 관한 연구

이규택,이종철 ( Kyu Taek Lee,Jong Chul Rhee ) 대한소화기학회 1992 대한소화기학회지 Vol.24 No.5

Delayed gastric emptying, so called idiopathic gastroparesis was already known to be one of the main causes of non-ulcer dyspepsia.But its pathophysiologic mechanism is not known yet. To test the role of neuro-hormonal dysfunction in its pathopysiologic mechanism, we studied serum gastrin in response to the meal and fasting state. Gastrin appears to increase the frequency of the gastric pacemaker and facilitates generation of action potentials; however the net effect of gastrin is known to retard gastric emptying. To verify any relationship between delayed GET and serum gastrin level, we measured fasting and postprandial 30 and 90 minutes serum gastrin levels by RIA method in 20 patients with idiopatic gastroparesis, in 20 patients with functional dyspepsia with normal GET, and in 20 normal control subjcts. The results were as follows: The percent of isotope remaining in the stomach at 90 minutes was 86.3+8.4% in idiopathic gastroparesis, 46.5+13.9% in functional dyspepsia, and 46.9+11.9% in normal controls. Fasting serum gastrin level was 112.4+24.6 pg/ml in idiopathic gastroparesis, 53.9+7.2 pg/ml in functional dyspepsia, and 58.6+5.9 pg/ml in normal control. The fasting serum gastrin level was significantly high (p<0.05) in patients with gastroparesis than in other groups, but there was no difference between functional dyspepsia and normal control. The serum gastrin level of postprandial 30 min. was 333.1+54.1 pg/ml in gastroparesis, 149.5+21.1 pg/ml in dyspepsia, 159.1+23.7 pg/ml in contol; and serum gastrin level of postprandial 90 min. was 228.0+38. 5 pg/ml in gastroparesis, 87.3+6.3 pg/ml in dyspepsia, and 73.7+7.7 pg/ml in control. There was a statistically significant correlation between delayed GET and increased serum gastrin level, and this, in turn, indicates that gastrin may play a major role in the pathophysiology of idiopathic gastroparesis.