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박기종 대한임상신경생리학회 2009 Annals of Clinical Neurophysiology Vol.11 No.1
Orthostatic intolerance is defined as the development of various symptoms during standing that are relieved by recumbency. Postural tachycardia syndrome (POTS) is another nomenclature of orthostatic intolerance. POTS characterized by a heart rate increase ≥30 bpm from supine to standing or >120 bpm at standing without orthostatic hypotension. POTS is a heterogenous in presentation with various pathophysiologic mechanisms. Important mechanisms are hypovolemia, denervation, hyperadrenergic and deconditioning state. There are presented as lightheadness or dizziness, palpitations, presyncope, sense of weakness, tremulousness, shortness of breath. POTS are classified under 3 groups that are neuropathic, hyperadrenergic, and deconditioning POTS. Most patients can be improved from a pathophysiologically based regimen of management.
박기종 대한임상신경생리학회 2012 Annals of Clinical Neurophysiology Vol.14 No.1
Thermoregulatory sweat is principal mean for homeostasis of temperature. Sweat glands have eccrine gland, apocrine gland,and apoeccrine glands. Disorders of sweating are manifested by excess (hyperhidrosis) or deficit (hypohidrosis, anhidrosis)of sweat. Hyperhidrosis can be defined as excessive sweating beyond a level required to maintain normal body temperature. The sweating can be generalized or localized (axilla, palms, soles, palmar-plantar, perineal). Usually hypohidrosis or anhidrosis may be more serious than hyperhidrosis. Hyperhidrosis is usually benign, but interferes with one’s daily activities. First step for diagnostic approach for sweating disorders might be dividing them into localized or generalized, and primary or secondary forms. Treatement for hyperhidrosis include topical agents, botulinum toxin A injections, systemic anticholinergics, and sympathectomy.
박기종,정희정 대한임상신경생리학회 2014 Annals of Clinical Neurophysiology Vol.16 No.2
Heart rate variability is significantly associated with cardiovascular complications in various neurological disorderswith cardiac impairment. Measures of spontaneous heart rate variability might be different from provocating tests ofheart rate variability such as deep breathing and Valsava maneuver. Methods for analysis are divided into time domainmethods and frequency domain methods. There are standard deviation of NN interval, standard deviation of average NNinterval, root mean square of the successive differences, NN50, and pNN50 in time domain methods. Frequency domainbands can be divided into very low, low, and high frequency. Each variables are influenced by sympathetic and/or parasympatheticactivity.