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김철호,이명묵,고경수,최윤식,서정돈,채인호,한규록,류오열,신원석,조명찬 대한내과학회 1991 대한내과학회지 Vol.41 No.6
To evaluate the survival and embolic events of idiopathic dilated cardiomyopathy (IDCMP), we followed up 80 patients diagnosed as IDCMP between 1984 and 1989 on the basis of clinical findings and echocardiography. We analyzed the clinical parameters, echocardiographic findings, and outcome. The following results were obtained: 1) Eighty patients, 58 male and 22 female (male: female = 2.6:1), with a mean age of 54±12 years (18 to 79 years) were included in this study. They were followed up for a mean of 30±26 months (ranging from 1 to 111 months). 2) By Kaplan-Meier method, the survival rates for 1, 2, and 5 years were 72%, 65%, and 58%, respectively. During the follow-up period, 27 patients died, and 24 of them (89%) died within 2 years of initial diagnosis. The causes of death were aggravation of congestive heart failure (22 cases, 81% of total deaths), sudden death (4 cases, 15%), and cerebrovascular disease (1 case, 4%). 3) There were significant differences (p$lt;0.05) between the survivors and those who died in left ventricular end systolic dimension (34.7±6.2 vs 38.8±6.5 mm/m), left ventriclar end diastolic dimension (41.2±616 vs 45.2±7.2 mm/m²), and ejection fraction (39.2±8.4 vs 34.1±7.6%), but age, sex, presence of embolism, clinical features, and electrocardiographic findings did not seem to influence the prognosis. 4) Cerebral embolism was found in 17 patients (21.3%), but including atrial fibrillation, there were no clinical variables predicting embolic events. Our data showed that 1) patients with idiopathic dilated cardiomyopathy had poor prognosis, 2) enlarged left ventricular end systolic dimension and end diastolic dimension, and decreased ejection fraction could be regarded as poor prognostic factors, 3) but there were no significant predictive factors for embolism.