家兎의 膝蓋骨 關節軟骨 損傷時 Prednisolone 注入이 軟骨再生에 미치는 影響에 關한 實驗的 硏究

盧永燮,李弘鍵 고려대학교 의과대학 1974 고려대 의대 잡지 Vol.11 No.2

The repair of the operative defects of articular cartilage has been a controversial subject among many authors, but usually it is accepted as the basic concepts that the injuries of hyaline cartilage heal with the formation of either fibrous tissue, fibrocartilage or atypical hyaline cartilage depending on the depth, location and size of the damage. Recently we apply much prednisolone to the joint diseases on orthopedics. We have no detailed literatures of regeneration and repair following the operative defects with the injection of prednisoione locally in the articular cartilage. Therefore the author has made an experimental study to observe the histological changes which were produced on the operative defects of the articular cartilage in rabbits to the patella with the local injection of prednisolone. Material and method: 132 rabbits, weighing 1500 to 2000gm, were divided into the control and prednisolone injection groups on half, then evenly were divided into 3 (A, B, C) groups depending on the depth of the surgical operative defects in the articular cartilage. A surgical operative defect was made on the articular cartilage of patella of each rabbit one half and three quarters in width of the cartilage surface parallel to the long axis of the patella. The depth of the operative defects were varied as follows: Group A: The defect was made on the intermediate or radiate zone of articular cartilage. Group B: The defect was extended to the calcified zone of cartilage and the subchondral bone was not exposed. Group C: The defect was created through the entire layer of the articular cartilage exposing the subchondral bone. The prednisolone injection group were injected locally with 5mg prednisolone dose into the operative defects of the articular cartilage before closing of arthrotomy on patella in rabbits. The animals with operative defects of each group were sacrified in 1, 2, 3, 4, 6, 8, 12, 13, 14 and 15 weeks after the operative procedures and then the patellas were removed, decalcified and stained with hematoxylin-eosin for microscopic examination. The summary of the histological changes on the operative defects is as follows: a) In controlled group: 1. The new hyaline cartilage was formed by cellular proliferation from the adjacent superficial zone of cartilage or directly from the adjacent margins of the remaining cartilage on the superficial defects involving the intermediate or partial radiate zone of the articular cartilage. 2. No new regenerative tissue development was observed on the defects involving to the calcified zone of articular cartilage and the subchondral bone was not exposed. 3. When the defect was exposed deeply down to the subchondral bone, the granulation tissue first derived from the subchondral intertrabecular tissue developed into the fibrous tissue which in turn underwent metaplasia to form immature hyaline cartilage. 4. Growth rate of new repair tissue on the defects was the most vigorous in the case in which the defects extended to the subchondral bone through the articular cartilage layers. 5. In the new growing reparative tissue formed at the site of the cartilage defects, the fibrous tissue, fibrocartiage and immature hyaline cartilage were seem to be distingushed. b) In prednisolone injected group: 1. The formation of the regenerative growing hyaline cartilage in the superficial defect involving the intermediate or partial radiate zone was either meager or absent. 2. In the defects involving up to the calcified zone only preserved, the formation of new growing tissue was seldom seen. 3. The new growing hyaline cartilage in the full thickness defect exposing the subchondral bone showed no changes in quality, but marked decrease in quantity with its fissuring. 4. The remained articular cartilage tissue after the operated defects was damaged by the prednisolone locally injected and the recovery of it began from 4 weeks and was 8 weeks as the controlled group. 5. The marrow cells and the other connective tissue were decreased in number after locally applied prednisolone on the defects and increased from 4 weeks and normalized 15 weeks as the controlled group.

회원작품 - 관저 예미지, 명가의 풍경

노영섭,Roh, Youngsoub 대한건축사협회 2018 建築士 Vol.588 No.-

TCP Performance Enhancement by Implicit Priority Forwarding (IPF) Packet Buffering Scheme for Mobile IP Based Networks

노영섭,허경,엄두섭,이연우,K. H. Tchah 한국통신학회 2005 Journal of communications and networks Vol.7 No.3

The smooth handoff supported by the route optimization extension to the mobile IP standard protocol should support a packet buffering mechanism at the base station (BS), in order to reduce the degradation in TCP performance caused by packet losses within mobile network environments. The purpose of packet buffering at the BS is to recover the packets dropped during inter-subnetwork handoff by forwarding the packets buffered at the previous BS to the new BS. However, when the mobile host moves to a congested BS within a new foreign subnetwork, the buffered packets forwarded by the previous BS are likely to be dropped. This subsequently causes global synchronization to occur, resulting in the degradation of the wireless link in the congested BS, due to the increased congestion caused by the forwarded burst packets. Thus, in this paper, we propose an implicit priority forwarding (IPF) packet buffering scheme as a solution to this problem within mobile IP based networks. In the proposed IPF method, the previous BS implicitly marks the priority packets being used for inter-subnetwork handoff. Moreover, the proposed modified random early detection (M-RED) buffer at the new congested BS guarantees some degree of reliability to the priority packets. The simulation results show that the proposed IPF packet buffering scheme increases the wireless link utilization and, thus, it enhances the TCP throughput performance in the context of various inter-subnetwork handoff cases.

一次抗結核劑에 對한 結核菌耐性에 關한 硏究

盧永燮 고려대학교 의과대학 1966 고려대 의대 잡지 Vol.3 No.1

Author studied on the bacteriological and clinical resistance to primary antituberculous drugs in 541 patients who were admitted to the National Kong-Ju Hospital between 1963 and 1964. The Ogawa's medium was used for the sensitivity test. The result was interpreted in 4 to 6 weeks of culture. The results are as follows; 1. The drug resistance to more than one primary antituberculous drugs occured in 428 cases out of 541 cases(79%). 2. The resistance to PAS developed in 288 cases (53%), to SM in 323 cases (60%) and to INH in 307 cases (57%) respectively. The incidence of combined resistance to SM and PAS, SM and INH and to PAS and INH were 11%, 11% and 6% respectively. 3. The incidence of resistance to primary antituberculous drugs depended on the duration of the disease and chemotherapy, the extent of tuberculous lesion and the presence of cavity. 4. In 145 cases (35%) out of 418 cases of medical treatment the sputums were converted to negative. Among the cases of medical treatment the sputums were converted to negative in 60% of non-resistant cases and in 25% of resistant cases. In 100 cases (81%) out of 123 cases of surgical treatment the sputums were converted to negative. Among the cases of surgical treatment the sputums were converted to negative in 96% of non-resistant cases and in 77% of resistant cases.

一次抗結核劑에 對한 結核菌耐性에 關한 硏究

盧永燮 首都醫科大學 1966 수도 의대 잡지 Vol.3 No.1

家兎의 膝蓋骨 關節軟骨 損傷時 Prednisolone 注入이 軟骨再生에 미치는 影響에 關한 實驗的 硏究

盧永燮 고려대학교 의과대학 1974 고려대학교 의과대학 잡지 Vol.11 No.2

고분말도 플라이애쉬를 사용한 모르타르의 공학적 특성에 관한 실험적 연구

노영섭(Rho Young-Seob),노형남(Rho Hyoung-Nam),김주상(Kim Ju-Sang),최세진(Choi Se-Jin),이상수(Lee Sang-Su),송하영(Song Ha-Young) 대한건축학회 2007 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.27 No.1

In case of using fly ash as some substitutes of cement, it is possible for us to improve durability through the improvement of liquidity and enhancement of water-tightness according to the effect by the ball bearing of mortar and concrete. It is widely used because it is very effective of decreasing the crack of concrete and improving the long-time strength through the decrease of heat of hydration, etc. However, it is severe in quality variation by the use of reckless substitutes, and it has large congelation retard, so there are disadvantages like the deterioration of performance on mortar and concrete due to the decrease of early strength. Accordingly, as a result of analyzing the strength, characteristics of congelation, and heat of hydration, etc. in order to examine the engineering properties of mortar using fly ash with high fineness in this study, this researcher could get excellent performance on the improvement of early strength and characteristics of heat of hydration according to the acceleration of congelation by the high fineness.

무인기 ECS의 수치적 모사 및 성능예측

노영섭(Youngsup Noh),박성순(Sungsoon Park),양진열(Jinyeol Yang),박승용(Seungryong Park) 항공우주시스템공학회 2017 항공우주시스템공학회 학술대회 발표집 Vol.2017 No.4

디지털 유방X-선촬영기의 구현

노영섭(Roh, Young-Sub),여세연(Yeo, Se-Yeon),이재준(Lee, Jae-Jun),손석원(Sohn, Surg-Eon) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.10

최근 디지털 유방촬영술 분야에서 영상의 획득장치, 표시장치, 저장장치는 각각 별도의 분야로 발전하고 있 다. 영상획득장치는 유방을 통과한 X-선을 흡수 포착하여 영상으로 저장하는 장치인데, 이를 이용하여 촬영된 영상 은 여러 가지의 영상처리기술을 이용하여 진단이 가능하기 때문에 조기에 병변을 발견할 수 있다. 본 논문에서는 지 금까지의 디지털 유방촬영술의 기술에 대하여 알아보고 구현된 디지털 유방X-선촬영기의 성능을 분석한다. The technologies of image acquisition, display, and storage of the breast have been developed in their specialized fields in recent years. The image acquisition system is a device that absorbs and stores images after examining breast tissue using X-ray. Due to the specificity and sensitivity of imaging, the early detection of breast cancer is feasible. In this paper, the current technologies for digital mammography are reviewed, and we propose a digital mammography and evaluate the performance of the implemented system.

모바일 IP 패킷 버퍼링 방식에서 TCP 성능향상을 위한 패킷 포워딩 우선권 보장 방안

허경,노영섭,엄두섭,차균현,Hur, Kyeong,Roh, Young-Sup,Eom, Doo-Seop,Tchah, Kyun-Hyon 한국통신학회 2003 韓國通信學會論文誌 Vol.28 No.8B

To prevent performance degradation of TCP due to packet losses in the smooth handoff by the route optimization extension of Mobile IP protocol, a buffering of packets at a base station is needed. A buffering of packets at a base station recovers those packets dropped during handoff by forwarding buffered packets at the old base station to the mobile user. But, when the mobile user moves to a congested base station in a new foreign subnetwork, those buffered packets forwarded by the old base station are dropped and TCP transmission performance of a mobile user in the congested base station degrades due to increased congestion by those forwarded burst packets. In this paper, considering the general case that a mobile user moves to a congested base station, we propose a Priority Packet Forwarding to improve TCP performance in mobile networks. In the proposed scheme, without modification to Mobile IP protocol, the old base station marks a buffered packet as a priority packet during handoff. And priority queue at the new congested base station schedules the priority packet firstly. Simulation results show that proposed Priority Packet Forwarding can improve TCP transmission performance more than Implicit Priority Packet Forwarding and RED (Random Early Detection) schemes. 모바일 IP 프로토콜에서 핸드오프 동안에 발생하는 패킷 손실 때문에 초래되는 TCP 성능 저하를 방지하기 위해서는 모바일 IP 경로최적화확장의 스무스 핸드오프 방식에서 이전 기지국이 핸드오프 동안 손실되는 패킷들을 버퍼에 저장하고 저장된 패킷들이 이동한 단말에게 전달되어야 한다. 그러나 무선링크가 병목인 일반적인 경우에서 이동단말이 새로운 서브 네트워크의 혼잡한 기지국으로 이동한 경우에는, 이전 기지국이 포워딩하는 패킷들은 손실되고 또한 이전 기지국이 포워딩하는 패킷들의 버스트한 도착 특성으로 인해 심화된 혼잡으로 기지국 내 이동단말 플로들의 TCP 전송 성능이 저하되게 된다. 본 논문에서는 기지국 패킷버퍼링방식이 결합된 스무스 핸드오프 방식으로 이동단말이 새로운 서브네트워크의 혼잡한 기지국으로 이동한 경우, 이동단말 플로들의 TCP 성능을 향상시키기 위해 이전 기지국에서 버퍼링된 패킷들에 대한 포워딩 트래픽 관리 방안으로서 패킷포워딩 우선권보장 방안을 제안하였다. 제안하는 패킷포워딩 우선권보장 방안에서는 모바일 IP 프로토콜의 수정 없이 이전 기지국이 핸드오프 동안 저장한 패킷들을 Priority 패킷으로 표기하고, 혼잡한 새로운 기지국에서는 Priority 패킷들을 Priority 큐로서 우선적으로 스케쥴링한다. 시뮬레이션 결과는 제안하는 패킷 포워딩 우선권 보장 방안이 RED 방식 및 암시적인 패킷 포워딩 우선권 보장 방안보다 이동단말들의 TCP 전송성능을 향상시킬 수 있음을 보인다.