물리적자극이 좌골신경 절단 마우스의 골격근에 미치는 영향

김철용,Kim, Chul-Yong 대한물리치료과학회 2003 대한물리치료과학회지 Vol.10 No.2

To demonstrate the effect of physical irritancy(massages) on the skeletal muscles of immobilization ddY mice models induced by right side sciatic nerve neurectomy, the cross sectional histological profiles of the muscularis (M) gastrocnemius, M. tibialis cranialis and M. tibialis caudalis were observed after 28 days of treatment of physical irritancy with the changes of body weight thickness of hind limb and individual muscle weights. In addition, changes of demonstrated with diameter of individual muscle fiber and muscle fasciculata, and number of muscle fiber in each of three types of muscles located in the calf. The massages were used in this study as physical irritancy. The experimental groups were divided into five groups, 1) Sham-operated group(Sham), 2) Neurectomized but not physical irritated control group(Control), 3) Neurectomized and physical irritated at knee pint regions(T1), 4) Neurectomized and physical irritated at calf regions(T2), and 5) Neurectomized and physical irritated at achilles tendon regions(T3). The experimental animals were used 5 per groups. The changes of number or diameter of muscle fiber in each muscles were calculated using automated image analyzer. The results are as follow : Thickness(diameter) of muscle fiber of M. gastrocnemius, M. tibialis cranialis and M. tibialis cranialis in right side of hind limb were remarkedly decreased in Control, T1, T2 and T3 groups compared to that of Sham group. However, the thickness was significantly increased in physical irritated groups compared to that of Control group in followed order : T3<T1<T2. 2. Thickness(diameter) of muscle fasciculata of M. gastrocnemius, M. tibialis cranialis and M. tibialis caudalis in right side of hind limb were remarkedly decreased in Control, T1, T2 and T3 groups compared to that of Sham group. However, the thickness was significantly increased in physical irritated groups compared to that of Control group in followed order : T3<T1<T2. 3. Number of muscle fiber in muscle fasciculata of M. gastrocnemius, M. tibialis cranialis and M. tibialis caudalis in right side of hind limb were remarkedly decreased in Control, T1, 72 and T3 groups compared to that of Sham group. However, the number was significantly increased in physical irritated groups compared to that of Control group in followed order : T3<T1<T2.

물리치료의 발전과제와 전망

김철용,Kim, Chul-Yong 대한물리치료과학회 1997 대한물리치료과학회지 Vol.4 No.2

21C's physical therapy in going to be changed by the new needs of medical demanders. Therefore we have to ready to treat these things. 1. The resolute alteration of curricula and scientific development of Korea physical therapy are urgent. 2. The levels of educational system have to be changed like developed country in short time and the master's, doctor's courses have to be formed in university. 3. The field of study has to be seperated by the needs and alterations of the times. And the association has to present vision for physical therapy's developing. 4. The university has to invest and support for training of great capacity's therapists.

자궁경부암의 방사선치료성적

김철용,최명선,서원혁,Kim, Chul-Yong,Choi, Myung-Sun,Suh, Won-Hyuck 대한방사선종양학회 1988 Radiation Oncology Journal Vol.6 No.1

One hundred fifty-four patients with the carcinoma of the uterine cervix were studied retrospectively to assess the result and impact of treatment at Department of Radiation Oncology, Korea University, Hae-Wha Hospital from Feb 1981 through Dec. 1986. Prior to radiotherapy, the patients were evaluated and staged by recommendation of FIGO including physical examination, pelvic examination, cystoscopy, rectosigmoidoscopy, chest X-ray, IVP. Ba enema. Also, an additional pelvic CT scan was obtained for some of the patients. The patients were treated by radiotherapy alone or adjuvant postoperative irradiation; in case of radiation therapy only, whole pelvic irradiation was given with Co-60 teletherapy unit via AP and PA parallel opposing fields or 4-oblique fields, 180 cGy per day, 5 days per week and intracavitary insertion was performed. In satges Ia, Ib, and IIa with small primary lesion, external irradiation was initially given to pelvis up to $2,000\~3,000\;cGy/2frac{1}{2}\;-3frac{1}{2}$ weeks and then intracavitary insertion was performed using Fletcher-Mini-Declos Applicator with cesium-137 cources and followed by external irradiation of $1,000\~2,000\;cGy/1frac{1}{2}\;-2frac{1}{2}$weeks via AP and PA parallel opposing fields with midline shield to spare of bladder and rectum. However, if the primary lesion is large, external irradiation was given without midline shield. More than stages IIb, the patients were treated by external beam irradiation up to 5,400cGy/30f for 6 weeks via 4-oblique portals and at the dose of 5,040cGy/28f the field was cut 5cm from the top margin for spare of small bowel, and followed by intracavitary irradiation, If there was residual tumor an additional dose of $900\~l,200cGy/5\~7f$ was given to parametrium and/or residual tumor area. Total dose of radiation to A and B-point were as follows; A-point; In early stages, Ia, Ib, IIa; $8,000\~9,000$ B-point $5,000\~6,000 cGy$ A-point; In advanced stages IIb, IIIa, IIIb; $9,000\~10,000$ B-point $60,000\~7,000cGy$ The results were obtained and as fellows; 1 The patients distribution according to FIGO staging system were stage Ia 6, Ib 27, IIa 28, IIb 54, IIIa 12, IIIb 18, and stage IVa 9. 2. Value of CT scan were demonstration of cervix tumor mass, parametrial and pelvic side wall tumor spread, pelvic and inguinal lymph nodes metastases, and hydronephrosis. Three dimensional quantitative demonstration of tumor volume is also important in planning radiation therapy. Another advantage of CT scan was detection of recurrent tumor after radiation or surgery. 3. Local control rate of tumor according to the size was $91.3\%$ for less than 5cm in size and $44.6\%$ in tumor over 5cm (p<0.0068). 4. Thirty out of 50 recurrent sites has locoregional failures and 17 cases has distant metastases. And the para-aortic lymph nodes were the most common site for distant metastases. 5. The most common complication was temporal rectal bleeding which was controlled most by conservative management. However, 4 patients required for endoscopic cauterization. 6. The 5-year survival rates showed; stage la and Ib $95\%,\;stage\;IIa\;81\%\;stage\;lIb\;67\%,\;stage\;IIIa\;37.7\%,\;stage\;IIIb\;23\%$ and 3-year survival rate of stage IVa showed $11.6%$, retrospectively.

마사지가 좌골신경 절단 마우스의 골격근에 미치는 영향

김철용,김성학,박상옥,배성수,박래준,Kim Chul-Yong,Kim Seong-Hak,Park sang-Ock,Bae Sung-Soo,Park Rae-Joon 대한물리치료학회 2003 대한물리치료학회지 Vol.15 No.2

To demonstrate the effect of massages on the skeletal muscles of immobilization ddY mice models induced by right side sciatic nerve neurectomy, the cross sectional histological profiles of the muscularis (M) gastrocnemius, M. tibialis cranialis and M. tibialis caudalis were observed after 28 days of treatment of massages with the changes of body weight, thickness of hind limb and individual muscle weights. In addition, changes of serum aspartate amino- transferase (AST) and creatine phosphokinase (CK) levels were also demonstrated with diameter of individual muscle fiber and muscle fasciculata, and number of muscle fiber in each of three types of muscles located in the calf. The experimental groups were divided into five groups, 1) Sham-operated group (Sham), 2) Neurectomized but not massage control group (Control), 3) Neurectomized and massage at knee joint regions (T1), 4) Neurectomized and massage at calf regions (T2), and 5) Neurectomized and massages at achilles tendon regions (T3). The experimental animals were used 5 per groups. The results are as follow: 1. No significant changes of body weight were demonstrated in this groups during whole experimental periods compared to that of Sham group. In addition, no significant changes of body weight gains during experimental periods (Day 0 - Day 27: 28 days of treatment) were also observed. 2. The thickness of intact left side hind limb was not changes in all tested groups compared to that of Sham group. However, the thickness of right side hind limb were remarkedly decreased in Control, T1, T2 and T3 groups compared to that of Sham group. In addition, the differences of thickness of hind limb between right and left sides were also significantly increased in Control and massage groups (T1, T2 and T3) compared to that of Sham group. However, the thickness of right side of hind limb were significantly increased and the differences of thickness between both sides of hind limb were dramatically decreased in massage groups compared to that of Control group in followed order: T1 > T3 > T2. 3. Absolute and relative weight of M. gastrocnemius in the intact left side of hind limb was not changes in all tested groups compared to that of Sham group. However, the weight of right side M. gastrocnemius were remarkedly decreased in Control, T1, T2 and T3 groups compared to that of Sham group. In addition, the differences of weight of M. gastrocnemius between right and left sides were also significantly increased in Control and massage groups compared to that of Sham group. However, the weight of right side M. gastrocnemius were significantly increased and the differences of weight between both sides of M. gastrocnemius were dramatically decreased in massage groups compared to that of Control group in followed order: T3 > T1 >. 4. Absolute and relative weight of M. tibialis cranialis in the intact left side was not changes in all tested groups compared to that of Sham group. However, the weight of right side M. tibialis cranialis were remarkedly decreased in Control, T1, T2 and T3 groups compared to that of Sham group. In addition, the differences of weight of M. tibialis cranialis between right and left sides were also significantly increased in Control and massage groups compared to that of Sham group. However, the weight of right side M. tibialis cranialis were significantly increased and . the differences of weight between both sides of M. tibialis cranialis were dramatically decreased in massage groups compared to that of Control group in followed order: T3 > T1 > T2. 5. Absolute and relative weight of M. tibialis caudalis in the intact left side was not changes in all tested groups compared to that of Sham group. However, the weight of right side M. tibialis caudalis were remarkedly decreased in Control, T1, T2 and T3 groups compared to that of Sham group. In addition, the differences of weight of M. tibialis caudalis between right and left sides were also significantly increased in Con

자궁경부암의 방사선치료성적

김철용(Chul Yong Kim)·최명선(Myung Sun Choi)·서원혁(Won Hyuck Suh) 대한방사선종양학회 1988 Radiation Oncology Journal Vol.6 No.1

One hundred fifty-four patients with the carcinoma of the uterine cervix were studied retrospectively to assess the result and impact of treatment at Department of Radiation Oncology, Korea University, Hae-Wha Hospital from Feb 1981 through Dec. 1986. Prior to radiotherapy, the patients were evaluated and staged by recommendation of FIGO including physical examination, pelvic examination, cystoscopy, rectosigmoidoscopy, chest X-ray, IVP, Ba enema. Also an additional pelvic CT scan was obtained for some of the patients. The patients were treated by radiotherapy alone or adjuvant postoperative irradiation; In case of radiation therapy only, whole pelvic irradiation was given with Co-60 teletherapy unit via AP and PA parallel opposing fields or 4-oblique fields, 180 cGy per day, 5 days per week and intracavitary insertion was performed. In satges Ia, Ib, and IIa with small primary lesion, external irradiation was initially given to pelvis up to 2,000~3,000 cGy/2½-3½ weeks and then intracavitary insertion was performed using Fletcher-Mini-Declos Applicator with cesium-137 cources and followed by external irradiation of 1,000~2,000 cGY/1½-2½ weeks via AP and PA parallel opposing fields with midline shield to spare of bladder and rectum. However, if the primary lesion is large, external irradiation was given without midline shield. More than stages IIb, the patients were treated by external beam irradiation up to 5,400 cGy/30f fot 6 weeks via 4-oblique portals and at the dose of 5,040 cGy/28f the field was cut 5 cm from the top margin for spare of small bowel, and followed by intracavitary irradiation. If there was residual tumor, an additional dose of 900~1,200 cGy/5~7f was given to parametrium and/or residual tumor area. Total dose of radiation to A and B-point were as follows; A-point : B-point In early stages, Ia, Ib, IIa : 8,000~9,000 5,000~6,000 cGy In advanced stages IIb, IIIa, IIIb : 9,000~10,000 6,000~7,000 cGy The results were obtained and as follows; 1. The Patients distribution according to FIGO staging system were stage Ia 6, Ib27, IIa 28, IIb 54, IIIa 12, IIIb 18, and stage lVa 9. 2. Value of CT scan were demonstration of cervix tumor mass, parametrial and pelvic side wall tumor spread, pelvic and inguinal lymph nodes metastases, and hydronephrosis. Three dimensional quantitative demonstration of tumor volume is also important in planning radiation therapy. Another advantage of CT scan was detection of recurrent tumor after radiation or surgery. 3. Local control rate of tumor according to the size was 91.3% for less than 5cm in size and 44.6% in tumor over 5cm (p<0.0068) 4. Thirty out of 50 recurrent sites has locoregional failures and 17 cases has distant metastases. And the para-aortic lymph nodes were the most common site for distant metastases. 5. The most common complication was temporal rectal bleeding which was controlled most by conservative management. However, 4 patients required for endoscopic cauterization. 6. The 5-year survival rates showed; stage la and Ib 95%, stage IIa 81% stage IIb 67%, stage IIIa 37.7%, stage IIIb 23%, and 3-year survival rate of stage IVa showed 11.6%, retrospectively.

國家賠償法 第2條에 관한 약간의 考察

金鐵容(Kim Chul-Yong) 한국법학원 1972 저스티스 Vol.10 No.1

독일(獨逸)과 일본(日本)의의 행정사차법(行政節次法)의 최근동향(最近動向)

김철용 ( Chul Yong Kim ) 건국대학교 법학연구소 1999 一鑑法學 Vol.4 No.-

고분자 첨가제에 따른 잉크흡수 특성 변화

김철용 ( Chul Yong Kim ),이명천 ( Myung Cheon Lee ) 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.2

바인더용 고분자 첨가제에 따른 잉크젯 인화지의 잉크흡수 특성변화

김철용(Chul Yong Kim),이명천(Myung Cheon Lee) 한국고분자학회 2006 폴리머 Vol.30 No.6

뇌종양의 수술 중 방사선치료

김철용 ( Chul Yong Kim ) 대한뇌종양학회 2002 대한뇌종양학회지 Vol.1 No.2

High-grade malignant gliomas are the most common brain tumors of the adult and about 30-45% of the primary brain tumors. The prognosis of high-grade malignant brain tumors is very poor. Surgical removal of tumor is a good treatment modality in brain tumors. The pattern of failure after surgery is almost local failure. Even in improving both local and systemic treatment, there is the local residual or recurrent tumors within 2-3cm of the primary site. Irradiation is the most effective adjuvant treatment modality and is therefore a mandatory treatment after maximal surgical removal for the highgrade malignant brain tumors. The benefit of postoperative irradiation has been reported in randomized clinical trials(Brain Tumor Cooperative Group, Brain Tumor Study Group, and Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group). But there is still high local residual and/or recurrent tumor. Intraoperative irradiation(IORT) is an alternative treatment as loco-regional treatment for high-grade malignant brain tumors. The rationale for IORT is 1) tumor unifocality, 2) pattern of recurrence in or close to the primary site, 3) radiation dose-tumor response correlation, 4) to spare normal brain tissue from single large doses delivered directly into the tumor bed. IORT is an tolerable, feasible, and attractive treatment modality as an aggressive local procedure for malignant brain tumors. The published experiences suggested that IORT is an effective complement to surgery and conventional external irradiation in the loco-regional treatment for brain tumors and showed encouraging preliminary results as compared with historical conventional treatments, without an increase in side effects. Further study in IORT must investigate several factors such as the optimum dose, the combination of biological modulators, the precision of target tumor volume, the method to optimize the dose distribution into the tumor, and the accuracy in the delivery of the prescribed total dose.