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김승남,구영,류인철,함병도,배기환,한수부,정종평,최상묵,Kim, Seung-Nam,Ku, Young,Rhyu, In-Cheol,Hahm, Byung-Do,Bae, Ki-Hwan,Han, Soo-Boo,Chung, Chong-Pyoung,Choi, Sang-Mook 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.1
The purpose of this study was to evaluate the antimicrobial activity of Crassirhzimae rhizoma and its possible use as an oral antiseptics for prevention of periodontitis. Its antibacterial activity against periodontopathic microorganisms including Actinobacillus actiomycetem - comitans, Capnocytophaga ochracea, Streptococcus mutans, Porphyromonas gingivalis, Prevotella intermedia, Actinomyces viscosus, Fusobacterium nucleatumwas evaluated via modified stab culture method. The cytotoxicity against gingival fibroblasts and rat osteoblasts was investigated via [$^3H$]thymidine incorporation and cellular activity was investigated via MTT assay. Chlorhexidine was used as control group. Crassirhizomae rhizoma was prepared at concentrations of 0.2, 0.15, 0.1, 0.05%. Chlorhexidine was also prepared at the same concentration. Crassirhizomae rhizoma showed lower antimicrobial antivity against these microorganism than chlorhexidine, but this difference was not significant. And, Crassirhzomae rhizoma showed more cellular activity and less cytotoxicity than chlorhexidine on human gingival fibrablast and rat osteoblast. This study suggests that Crassirhzomae rhizoma might be a candidate for a safe oral antiseptic for the prevention and treatment of periodontal disease.
간장 ( 肝腸 ) 및 담도 ( 膽道 ) : 원발성간암의 임상적 고찰
김승남(Seung Nam Kim),주상용(Sang Yong Choo),이종서(Jong Seo Lee),이종화(Jong Wha Lee),김응국(Eung Kook Kim) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.3
N/A Primary hepatoma have been relatively common due to developed diagnostic maneuver. This tumor is quite prevalent in Asia, Africa and cirrhosis is an etiologic factor as concomittant disease. Recently large number of surgeon reported excellent surgical result. This report is clinical review of 50 patients who were diagnosed as a primary hepatoma at the Department of Surgery, Catholic University Medical College from March, 1978 to December, 1989. The following results were obtained: 1) The male to female ratio was 5.2:1. The age distribution indicated a prominent incidence between 4th. and 5th. decade. 2) Symptom and signs on admission were right upper quadrant abdominal pain (72%), malaise (20%), indigestion (12%), fever (12%). The liver cirrhosis was associated in 23 cases (46%). 3) The most common anatomical location of tumor was right lobe in 32 cases (64%) and the size of tumor was most common in 5~10 cm (24 case, 48%). 4) Histopathological examination revealed hepatocellular carcinoma (45 cases, 90%), cholangiocarcinoma (2 cases) and hepatoblastoma (2 cases). 5) Hepatic resection was performed in 30 cases (60%) and others were hepatic artery ligation in 14 cases (28%) and exploration and biopsy in 6 cases (12%). 6) Postoperastive complications were noted in 12 cases (24%), among which pleural effusion was most common (12 cases) and the other complications were postoperative bleeding (5 cases), hepatic coma (4 cases). 7) Overall hospital mortality was 24% and the cause of death were hepatic failure (6 cases), hepatorenal syndrome (3 cases), GI bleeding postoperative bleeding and D.I.C.
김승남(Seung Nam Kim),주상용(Sang Yong Choo),이종서(Jong Seo Lee),오세정(Se Jeong Oh),김응국(Eung Kook Kim) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2
N/A This study was based on 5 patients with hepatic cavernous hemangioma who had been admitted and treated at Dept. of Surgery, St. Mary's Hospital of Catholic University Medical College, over a period 3 years from 1986 to 1988. The results were as follows: 1) Male was affected more than female (4 cases), and the patients ranged in age from 35 years to 58 years. 2) The common symptom and sign were fatigue, abdominal pain, and fever, among them fatigue was most frequent (4 cases). 3) The hepatic artery angiogaphy, CT, ultrasonography, liver scan and laparoscope were used for diagnosis, among them hepatic artery angiogrphy and CT were most frequent (5 cases). 4) The tumor was located in Rt. Lobe of liver, 3 cases; Lt. Lobe, 2 cases. Of which size were ranged from 2 cm to 5 cm. 5) The operation was performed with Lt. Lat. Segmentectomy, 2cases; partial resection, 2 cases; Rt. Lobectomy of liver, 1 case. 6) The blood loss during operation was transfused in 4 cases which averaged 1260 ml. 7) Postoperative complications occurred in 2 cases. Which were atelectasis and wound abscess.
심상인(Sang In Shim),김승남(Seung Nam Kim),이재학(Jai Hak Lee),주상용(Sang Yong Choo),이종서(Jong Seo Lee),이준(June Lee) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2
N/A The leiomyoblastoma of the stomach is an unusual smooth muscle tumor, which was first described by Martin and others in 1960. The gastric leiomyoblastoma is similar to the smooth muscle tumor of leiomyosarcoma in gross and composed of round or polygonal cells instead of spindle cells microscopically. Most of these tumors are benign but some tumors behave in malignant manner. The leiomyoblastoma has better prognosis than other smooth muscle tumors. Recently we experenced a case of leiomyoblastoma of the stomach and report with brief review of literatures.
김성근(Sung Geun Kim),송교영(Kyo Young Song),김승남(Seung Nam Kim),박조현(Cho Hyun Park) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.1
Purpose: There is concern about the potential adverse effects on hepatic function due to increased intraabdominal pressure during pneumoperitoneum. The changes in hepatic function following a laparoscopy assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for gastric cancer were compared. Methods: Between July 2004 and May 2005, 60 patients diagnosed with early gastric cancer at Kangnam St’ Mary’s hospital; 30 each having undergone LADG and ODG were studied. The levels of alkaline phosphatase (ALP), total bilirubin (TB), aspartate transferase (AST) and alanine transferase (ALT) between the two groups were compared at 24 and 72 hours postoperatively. Results: The age, sex, body mass index and preoperative hepatic function were not different between the two groups. The operative times were significantly longer in the LADG than the ODG group (298 vs. 184 minutes, P<0.000). There was no postoperative hepatic failure or mortality in either group. The levels of ALP decreased, but those of total bilirubin remained unchanged from the preoperative baselines in both groups, with no significant difference between the two groups. After a LADG, the levels of AST and ALT increased 3.7 and 3.5 fold 24 hours after surgery, whereas after an ODG, the levels of AST and ALT increased 1.9 and 1.5 fold. In the LADG group, the levels of AST and ALT were significantly increased compared to the ODG group (P<0.05), but returned close to the baseline levels within 72 hours. On the third postoperative day, there were no significant differences in the levels of AST and ALT between the two groups (P>0.05). Conclusion: After a LADG, the levels of hepatic transaminases were immediately elevated, but returned to normal levels within 72 hours. A LADG with prolonged pneumoperitoneum is considered safe in patients with normal liver function prior to the operation. In addition, to evaluate the safety of a LADG in the patients with decreased hepatic function, a large scaled randomized prospective trial will be required.
GISTs에서 증가된 Ki67 Index (>10%)와 p53 단백발현의 예후 인자로서의 유용성
손보성(Bo Sung Sohn),전해명(Hae Myung Jeon),성기영(Gi Young Sung),진형민(Hyung Min Jin),김욱(Wook Kim),박조현(Cho Hyun Park),박승만(Seung Man Park),임근우(Keun Woo Lim),박우배(Woo Bae Park),김승남(Seung Nam Kim),이교영(Kyo Young Lee 대한외과학회 2004 Annals of Surgical Treatment and Research(ASRT) Vol.66 No.2