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골반경사 운동과 보행훈련이 편마비 환자의 보행특성에 미치는 영향
곽길환,이동욱,배성수,Kwak Kil-Hwan,Lee Dong-Wook,Bae Sung-soo 대한물리치료학회 2003 대한물리치료학회지 Vol.15 No.3
The purpose of this study was to examine the effects of the pelvic tilting exercise, pelvic tilting exercises with floor walking training, pelvic tilting exercises with treadmill walking training on quantitative gait function in patients with hemiplegia. Thirty patients with hemiplegia due to cerebrovascular disease participated in this study. Subjects were randomly assigned to one of pelvic tilting exercise group, pelvic tilting exercise with floor walking training group and pelvic tilting exercises with treadmill walking training group. The effects of each therapeutic method were evaluated by measurements of gait velocity, cadence, stride length, step length, base of support and foot angle using ink-foot prints. Data were analyzed statistically using paired t-test and one-way ANOVA. The results of this research are as followings : 1. After treatment, it turned out that pelvic tilting exercises with treadmill walking training has the most effect on gait velocity, cadence, stride length, step length and foot angle, which has significant difference in statistics (p<0.05). 2. Quantification of the gait velocity, cadence, both stride length and step length demonstrated a significant increase (p<0.05) after treatment in all groups when compared with values measured before treatment. The base of support and foot angle in affected side decreased significantly (p<0.05) after treatment in all groups when compared with values measured before treatment. 3. The lumbosacral angle noted a significant increase (p<0.05) after treatment in all groups, however, an ANOVA analysis did not reveal any differences between groups.
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편마비환자의 환측 하지 외회전 정도가 기립균형에 미치는 영향
이동욱,곽길환,배성수,Lee Dong-Wook,Kwak Kil-Hwan,Bae Sung-soo 대한물리치료학회 2003 대한물리치료학회지 Vol.15 No.3
The two groups each consisting of 28 people who had an adult hemiplegia due to a brain injury received two different methods of exercises to reduce the angle to which the affected lower limb rotates externally. The comparisons between the two groups were made for the changes of the angle in external rotations measured between pre and post test. The static balance index values taken during pre and post tests were also compared. In addition, the correlations of the angle to which the affected lower limb rotates externally with static balance index values were analyzed. The result were as follows: 1. A statistical analysis indicated that in group one having taken simple R.O.M exercises, the angle to which the affected lower limb rotates externally and the static balance index values were both significantly different between pre and post test (P<.01). 2. A statistical analysis indicated that in group two having taken a pattern movement, both the angle to which the affected lower limb rotates externally and static balance index values were significantly different between pre and post test (P<.01). 3. A significant difference between simple R.O.M exercises group and pattern movement exercises groupwas shown only for the angle to which affected limb rotates externally not for static balance index values (P<.01), 4. Pearson correlation coefficient for the angle to which the affected limb rotates externally with static balance index values was found to be significant only in pattern movement exercises group (P < .05).
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가금티푸스 예방을 위한 adjuvant로서 mastoparan V1을 사용한 포르말린-불활화 Salmonella Gallinarum 사균체 백신의 효능 평가
문자영,곽길환,Enkhsaikhan Ochirkhuyag,김선민,이준우,조영규,김원경,방우영,배창환,허 진 한국동물위생학회 2019 韓國家畜衛生學會誌 Vol.42 No.4
Mastoparan V1 was used as adjuvant of formalin-inactivated Salmonella Gallinarum whole cells vaccine against fowl typhoid in a chicken model. The 75 brown nick chickens were equally divided into 5 groups, and all chickens of each group were immunized at 6 weeks of age (0 WPPI; weeks prime post immunization), and at 9 weeks of age (3 WPPI) (except group B). Group A chickens were intra-muscularly (IM) inoculated with 500 uL of sterile phosphate-buffered saline (PBS), and group B chick-ens were subcutaneously immunized with 0.2 ml containing 5×107 viable vaccine strain/bird. The chick-ens in groups C∼E were IM inoculated with approximately 3×109 cells/0.5 mL of formalin-inactivated the S. Gallinarum whole cells, approximately 3×109 cells/0.5 mL of formalin-inactivated the S. Gallinarum whole cells with mastoparan V1 as adjuvant, and 0.5 mL of PBS, respectively. S. Gallinarum outer membrane proteins-specific serum IgG titers were considerably higher in groups B∼D than in groups A and E. However, the levels of IFN- in groups B and D only than in groups A and E were sig-nificantly higher. Following oral challenge with virulent wild-type S. Gallinarum, no chicken in groups A (no challenge group) and B was dead, and only 30% of chickens in group D was dead. However, 70% of chickens in group C and all chickens in group E were dead after oral challenge. The results of this study demonstrated that IM immunization with approximately 3×109 of the formalin-inactivated S. Gallinarum whole cells containing mastoparan V1 induced robust antibody and cell-mediated immune responses in chickens. The whole cells also conferred protection against infection with wild-type S. Gallinarum.
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