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고혁 ( Hyuk Ko ),최수정 ( Soo Jung Choi ),장현규 ( Hyun Kyu Chang ),김종완 ( Jong Wan Kim ),김승렬 ( Seong Reol Kim ) 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.3
Juvenile rheumatoid arthritis (JRA) can develop the extra-articular manifestations, which are growth retardation, osteopenia, chronic uveitis, and rarely pleuropulmonary involvement. Approximately 30% of patients with JRA show abnormal pulmonary function test without pulmonary symptoms, in which the frequent abnormality is in carbon monoxide diffusing capacity, but clinically evident pulmonary parenchymal disease in JRA is extremely uncommon. We describe a 23-years-old female with JRA who presented with dyspnea due to interstitial lung disease and pulmonary hypertension. She had suffered from polyarthralgia and dyspnea since 8 years old.
박성오(Sung Oh Park),고혁(Hyuk Ko),김수희(Su Hee Kim),박배근(Bae Keun Park),김승용(Seung Yong Kim),유철희(Chul Hee You),김연석(Youn Suk Kim) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.6
Hepatic epithelioid hemangioendothelioma (HEH) is a rare vascular tumor of the liver. HEH is endothelial origin, and has a intermediate clinical course between benign hemangioma and an angiosarcoma of the liver. It usually appears as multiple hypoechoic nodules on US scan and hypodense on CT scan. Definite diagnosis is made by histopathology of specimens obtained from the tissue biopsy. We present a case of HEH which presented with multiple nodules within the liver on CT scan. The diagnosis was made by laparoscopic liver biopsy. (Korean J Gastroenterol 2001;38:433-435)
김수희 ( Su Hee Kim ),박성호 ( Sung Oh Park ),고혁 ( Hyuk Ko ),박양순 ( Yang Soon Park ),원경숙 ( Kyoung Sook Won ),장현규 ( Hyun Kyu Chang ) 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.1
Sjogren`s syndrome is a chronic, slowly progressive, autoimmune disease in which the exocrine glands are damaged by lymphocytic infiltration, resulting in xerostomia and xerophthalmia. Fever in patients with Sjogren`s syndrome is rarely manifested with the exception of cases with complicated illness such as lymphoma. We experienced a 70-year-old male patient with Sjogren`s syndrome who was presented with fever of unknown origin. Despite of thorough investigation, other diseases to cause fever could not be found. Fever and other clinical features were improved with empirical steroid therapy.
항-RNP 항체가 있는 전신성 경화증 환자에서 Sulindac 투여 후 발생한 담즙울체성 간염과 급성췌장염
장현규 ( Hyun Kyu Chang ),김연석 ( Yeon Suk Kim ),정훈 ( Hoon Jeong ),박성오 ( Sung Oh Park ),김수희 ( Su Hee Kim ),고혁 ( Hyuk Ko ),강길현 ( Gil Hyun Kang ),김정욱 ( Jeong Uk Kim ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.2
Sulindac is a commonly used nonsteroidal anti-inflammatory drug (NSAID). It is relatively economical arid seems to be less nephrotoxic due to its property of minimal renal prostaglandin inhibition. Although hepatic injury has been infrequently reported for nearly all NSAIDs currently on the market, sulindac has more commonly been associated with hepatotoxicity. In addition, it has been known that sulindac is the agent to have a definite association with pancreatitis. We describe a 37-year-old woman who developed cholestatic hepatitis and acute pancreatitis in association with sulindac. This patient met the diagnostic criteria of both mixed connective tissue disease and systemic sclerosis, in which the disease classification needs to be clarified. While being treated with sulindac, close observation and periodic liver function test seem to play an important role.
김수희,박성오,고혁,박완,류대식,김종욱,정재걸,정복현 대한내과학회 2002 대한내과학회지 Vol.63 No.1
Aspergilloma and Allergic Bronchopulmonary Aspergillosis (ABPA) are different types of spectrum of pulmonary aspergillosis. ABPA results from hypersensitivity reaction to Aspergillus species and is known to be usually associated with bronchial asthma and cystic fibrosis. Aspergilloma results from simple colonization of this fungus within cavitary lung lesion or bronchiectasis. But rarely some patients can present together with ABPA and aspergilloma. We experienced a case of ABPA associated with aspergilloma in a 38 year-old male. The diagnosis was confirmed by asthma, immediate cutaneous reactivity to A. fumigatus, IgG antibody to A. fumigatus, elevated total and specific IgE antibodies to A. fumigatus, central bronchiectasis and peripheral eosinophilia coincident with radiographic infiltrates. During follow-up management with steroid, left pneumonectomy was done because of spontaneous pneumothorax with persistent air-leak and multidrug resistance pulmonary tuberculosis in association with aspergilloma. His respiratory symptoms and ABPA activity was much more improved after removal of aspergilloma. These findings suggest that surgical resection of aspergilloma can be considered to reduce antigenic source of colonized fungi in ABPA patients when associated with aspergilloma.