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고재웅,조형훈,양성원,허준,Jae Woong Koh,Hyung Hun Cho,Sung Won Yang,Jun Her 대한안과학회 2006 대한안과학회지 Vol.47 No.9
Purpose: To report cases of corneal perforation among corneas treated with cyanoacrylate tissue adhesive. Methods: We performed cyanoacrylate tissue adhesive application on 1 case of corneal perforation due to fungal keratitis, one case of corneal perforation due to neurotrophic keratitis, one case of corneal fistula due to foreign body and one case of corneal perforation due to corneal stromal dystrophy. After cyanoacrylate tissue adhesive removal, amniotic membrane transplantation was conducted in two cases, and keratoplaty was performed in another two cases. Results: Postoperative follow-up period was 12 months on average. In all four cases, ocular integrity was successfully restored. There was no sign of recurrence, infection or inflammation. Conclusions: Cyanoacrylate tissue adhesive monotherpy can restore ocular integrity successfully in various type of corneal perforation and After cyanoacrylate tissue adhesive removal, amniotic membrane transplantation and keratoplaty can be performed additionally.
양영성,고재웅.Young Seong Yang. MD. Jae Woong Koh. MD. PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.1
Purpose: To evaluate the efficacy of noncontact specular microscopy (NCSM) by comparing the measurement of central corneal thickness (CCT) to the measurement with anterior segment optical coherence tomography (AS-OCT) and ultrasound pachymetry (USP). Methods: One examiner measured the CCT of 50 eyes of 50 healthy young subjects using NCSM, AS-OCT, and USP. The mean values and correlations were analyzed. Results: The mean CCT value was 546.92 ± 32.06 μm with NCSM, 535.24 ± 30.54 μm with AS-OCT, and 546.38 ± 30.70 μm with USP. The CCT measurements with NCSM and USP were significantly thicker than with AS-OCT (p < 0.001, p < 0.001, respectively). There were no significant differences between the measurements obtained with NCSM and USP (p = 0.505). The 3 instruments were significantly correlated (r > 0.900 in all groups, p < 0.001 in all groups). Conclusions: CCT measurements of healthy eyes using NCSM are more correlated with USP than AS-OCT. The CCT measurement using NCSM is a better alternative for USP than AS-OCT. J Korean Ophthalmol Soc 2014;55(1):59-65
양유리,고재웅,최남영,박수철,Yoo Ri Yang,Jae Woong Koh,Nam Young Choi,Soo Chul Park 대한안과학회 2006 대한안과학회지 Vol.47 No.10
Purpose: To determine changes in the degree of pseudomyopia and convergence in patients with spasm of the near reflex. Methods: In 5 patients with spasm of the near reflex, we checked following: UCVA/BCVA, the degree of pseudomyopia revealed through manifest and cycloplegic refraction tests, pupil size, limitation of EOM, the amount of convergence defined by the alternate prism cover test, and slit lamp and funduscopic exams. Results: Of the 5 patients with spasm of near reflex, 3 had accommodative spasm alone and 2 had accommodative spasm, convergence spasm and miosis. The patients` degrees of pseudomyopia and convergence were -8.0D and 14PD on the average. which disappeared after an average of 10.8 months but recurred in 1 of the 3 patients with accommodative spasm. As for spasm of the near reflex, 1 patient showed improvement in convergence but worsening pseudomyopia during the follow-up period, and another patient showed recurrence. Conclusions: The most common clinical feature of spasm of the near reflex is accommodative spasm. Patients with accommodative spasm alone showed better prognosis among all patients with spasm of the near reflex in terms of recurrence and the disease course.
송낭희,고재웅,Nang Hee Song,Jae Woong Koh 대한안과학회 2012 대한안과학회지 Vol.53 No.11
Purpose: To investigate the regional characteristics and the factors that influence final visual acuity in corneal laceration and use the results for prevention and treatment of corneal laceration. Methods: Sixty-eight patients who visited the Chosun University Medical Center from January 1, 2006 to December 31, 2010 were retrospectively surveyed. The incidence of corneal laceration, sex, age, monthly and seasonal distribution, cause, site and length of corneal laceration, secondary operation, complications, and ocular trauma score were reviewed statistically. In additional, the factors influencing visual prognosis were investigated. Results: The incidence was more common in males (94.1%) and in the 6th-decade of life (29.4%). The corneal laceration was more common in the summer (38.2%) and in September (26.5%) and the most common cause was stone (39.7%) and metal (35.3%), respectively. The corneal laceration tended to occur at the corneal center. The most common first operation was primary closure (81.9%), and the secondary operation was most often performed due to a traumatic cataract (32.1%). The factors that significantly influenced the final visual acuity were initial visual acuity, length and site of laceration, and secondary operation. Conclusions: The present survey investigated the regional characteristics and important factors influencing final visual acuity. Results show initial visual acuity, the length and site of laceration, and the secondary operation significantly influenced final visual acuity.
정무오,고재웅.Mu O Jung. MD. Jae Woong Koh. MD. PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.12
Purpose: To introduce a more efficient and time-saving scleral fixation technique for a posterior chamber foldable intraocular lens and to report the clinical results. Methods: A foldable acrylic 3-Piece IOL was sutured to the sclera via a small corneal incision. The guiding hollow needle was not used, which differs from other ab externo techniques. Instead, the curved long needle was directly pulled out through the cornea. The scleral flap was not used to bury the scleral suture knot; Instead, the scleral suture knot was translocated at the temporal area. Results: A total of 30 cases were studied retrospectively. The mean follow-up period was 2 years. The IOL was correctly positioned in all cases. There were no major complications, such as endophthalmitis or suture erosion through the conjunctiva. Conclusions: Based on the authors’ experience, the modified ab externo and one-knot technique is a faster and easier technique than the conventional ab externo technique.
포도당 농도가 인간 수정체상피세포의 반응성 산소 생성량의 변화에 미치는 영향
양유리,이병래,고재웅,Yoo Ri Yang,Bypung Rai Lee,Jae Woong Koh 대한안과학회 2006 대한안과학회지 Vol.47 No.5
Purpose: To investigate the effects of glucose concentrations on the formation of reactive oxygen products and cellular injury in human lens epithelial (HLE) cells. Methods: Human lens epithelial (HLE) cells were cultured with high glucose (200 mg/100 ml, 300 mg/100 ml, 400 mg/100 ml) and normal glucose (100 mg/100 ml) contained Modified Egle`s Medium (MEM). The amounts of reactive oxygen products were assayed by dihydroethidium (DHE). Paraquat-induced cytotoxicity was determined by the 3-[4,5-dimethylthiazol-2-yl]-2,5 -diphenyl tetrazolium bromide (MTT) method. Results: Reactive oxygen products of human lens epithelial cells increased 110%, 250% and 630% in the high glucose (200 mg/100 ml, 300 mg/100 ml, 400 mg/100 ml) media compared to the normal glucose (100 mg/100 ml) media. The paraquat-induced cells toxicity was increased by the high glucose. Conclusions: High glucose increased the formation of reactive oxygen products in human lens epithelial cells. These results suggest that high glucose can induce cataract formation in diabetic patients.
박정현,송낭희,지남철,고재웅,Jung Hyun Park,MD,Nang Hee Song,MD,Nam Chul Chi,MD,PhD,Jae Woong Koh,MD,PhD 대한안과학회 2010 대한안과학회지 Vol.51 No.9
Purpose: Chemical lights, also called Luminous Sticks, consist of a solution of diphenyl oxalate (C14H10O4) and hydrogen peroxide (H2O2). Human tissue can be damaged when the mixed solution contacts the human body. The authors report a single case of chemical injury of keratoconjunctiva by exposure to chemical lights. Case summary: A 47-year-old man’s right eye accidentally contacted the fluorescent material when breaking a Luminous Stick 7 days before being referred to our clinic. He had pain in the right eye and experienced visual loss. The patient’s best corrected visual acuity in the right eye was 20/50. An ulcerative lesion with edema at the inferior bulbar and palpebral conjunctiva and coneal epithelial defect was observed upon biomicroscopic examination. The patient was hospitalized and antibiotics, steroids, mydriatic and artificial tear eye drops were applied for treatment. After 9 days of treatment, the best corrected visual acuity of the patient recovered to 20/20, and the conjunctiva and cornea were mostly healed. No complication was observed. Conclusions: Chemical lights are commonly used in concerts and festivals. If the contents contact the eyes when breaking the chemical lights, various chemical burns can occur and cause ophthalmologic complications. Since no regulations have been passed regarding chemical lights, safety education and supervision are considered to be necessary for children. J Korean Ophthalmol Soc 2010;51(9):1282-1286