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金炯祐,徐城鐸,全燾基 中央醫學社 1973 中央醫學 Vol.25 No.2
In order to know the current status of sensitivity of urinary and enteric pathogens including pathogenic vibrios to some antimicrobial agents of current use, the sensitivity of these organisms isolated in recent years from. pathological sources except most of Vibrio parahaemolyticus which were isolated from marine sources) was studied by the agar plate dilution method. The antimicrobial agents tested were kanamycin (Kan), gentamicin (Gen), penicillin G (Pen), ampicillin (Amp), neomycin (Neo), oxytetracycline (0-Tet), minocycline (Min), doxycycline (Dox), furilin (Fur), streptomycin (Str), chloramphenicol (Chl), erythromycin (Ery), colistin (Col), carbenicillin (Carb), polymyxin .B (PxB), trimethoprim (TMP), sulfamethoxazole (SMX) and the mixture of TMP-SMX. Urinary isolates was classified into two major species, staphylococci and Escherichia coli, and the others were enteric gram negative bacilli and gram positive. cocci. These organisms were sensitive to Gen but resistant to most of antimicrobial agents of current use. They were especially resistant to Str, Kan, Pen, Amp, Chlr O-Tet, TMP-SMX and Col. Salmonella was strongly sensitive to Kan and moderately sensitive to drugs other than TMP-SMX, Ery and Col. Shigella was strongly sensitive to Kan, Gen and Amp, but highly resistant to Stir,
김형우,허중연,이용문,SJ Kim,정혜원 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.4
Pneumocystis jirovecii pneumonia (PJP) in patients with HIV infection can, in rare cases, present with pulmonary nodules that histologicallyinvolve granulomatous inflammation. This report describes an intriguing case of granulomatous PJP with pulmonarynodules after commencing antiretroviral therapy (ART) in an HIV-infected patient without respiratory signs or symptoms. Diagnosisof granulomatous PJP was only achieved through thoracoscopic lung biopsy. This case suggests that granulomatous PJP shouldbe considered in the differential diagnosis of pulmonary nodules in HIV-infected patients for unmasking immune reconstitutioninflammatory syndrome manifestation after initiation of ART.
AM3359 마이크로프로세서 기반 임베디드 시스템 설계 및 제작
김형우,김세준,최준영,Kim, Hyoung-Woo,Kim, Se-Jun,Choi, Joon-Young 대한임베디드공학회 2017 대한임베디드공학회논문지 Vol.12 No.2
We develop an embedded system to measure various sensor data, control multiple motors, and communicate with mobile devices for system managements. Choosing TI AM3359 microprocessor featuring high processing performance, low power consumption, and various I/O device support, we design and build the embedded system hardware so that it supports multiple global positioning system (GPS) and gyro sensor modules to measure precise position; multiple pulse width modulation (PWM) outputs to control multiple direct current (DC) motors; a Bluetooth module to communicate with mobile devices. Then, we port the boot loader and device drivers to the built circuit board and construct the firmware development environment for the application programming. The performance of the designed and implemented embedded system is demonstrated by real motor control test using GPS and gyro sensor data and control parameters configured by a mobile device.
김형우,문두건,김현민,황종호,김순찬,남삼극,박준탁 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.10
Purpose: Combination therapy of a-blockers and 5α-reductase inhibitors (5-ARIs) is widely used for the treatment of benign prostatic hyperplasia (BPH). We aimed to study the effect on prostate volume and symptoms of shifting to monotherapy in patients who previously received a combination therapy. Materials and Methods: A prospective study was conducted of 60 patients who were diagnosed with BPH. Patients were aged 45 years or older and had a prostate volume of 30 cc or more, International Prostate Symptom Score (IPSS) of 12 or above, maximal flow rate (Qmax) of 15 ml/s or less, and prostate-specific antigen (PSA) level of less than 10 ng/ml. The patients initially received a combination therapy of doxazosin 4 mg/day and finasteride 5 mg/day for 3 months and were then randomly assigned to receive monotherapy for 3 months. The factors were then compared. Results: A total of 30 patients were assigned to doxazosin (group 1) and 30 to finasteride (group 2) after the combination therapy. The percentage changes in prostate volume, IPSS, and Qmax during the period from post-combination therapy to post-monotherapy were not significantly different between the two groups (p=0.052, 0.908, 0.081), whereas PSA significantly decreased in group 2 (p<0.001). IPSS was not significantly different at post-combination therapy and at post-monotherapy in both groups (p=0.858, 0.071). The prostate volume significantly increased from 40.97 cc at post-combination therapy to 44.29 cc at post-monotherapy in group 1 (p=0.001) and insignificantly increased from 38.32 cc to 38.61 cc in group 2 (p=0.696). Conclusions: Although the duration of drug administration was short in this study, 5-ARI monotherapy could maintain the alleviated symptoms and reduce the risk of acute urinary retention and surgery due to prostate regrowth in BPH patients whose symptoms improved with combination therapy.
F-67 Clinical utility of medical thoracoscopy, a single center experience
김형우,신아영,김주상,안중현,하직환 대한결핵 및 호흡기학회 2016 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.121 No.-
Aim: Medical thoracoscopy has many advantages in diagnosis of pleural disease, with high accuracy of diagnosis avoiding the risk of general anesthesia. This study aimed to describe clinical utility and diagnostic yield of medical thoracoscopy in a single center. Method: Medical record of 25 patients who underwent medical thoracoscopy was retrospectively reviewed. Result: Among 25 patients, 19 patients were with clinical impression of pleural malignancy according to positive results of at least one below: pleural fluid cytology, pleural fluid tumor marker, lung parenchymal lesion suspicious of malignancy on initial chest CT. Among them, 17 patients underwent medical thoracoscopy as an initial procedure for pathologic diagnosis - 7 of them had no lung parenchymal lesions suspicious of malignancy, 10 of them had lung parenchymal lesions thought to be inaccessible or difficult to access by bronchoscopic or percutaneous approach. Among 25 patients, 18 patients were finally diagnosed as pleural malignancy with pathologic evidence. In all malignant cases including 4 cases of cryobiopsy and 1 case of hot biopsy, the amount of pleural tissue obtained with medical thoracoscopy was enough to undergo immunohistochemical stain. Sensitivity, negative predictive value and diagnostic accuracy for pleural malignancy were all 100% Conclusion: Medical thoracoscopy has high accuracy in diagnosis or exclusion of pleural malignancy.
웹서비스와 스마트폰앱을 이용한 연안해양모델 예측자료의 시각화시스템 구현
김형우,구본호,우승범,이호상,이양원,Kim, Hyung-Woo,Koo, Bon-Ho,Woo, Seung-Buhm,Lee, Ho-Sang,Lee, Yang-Won 한국공간정보학회 2014 한국공간정보학회지 Vol.22 No.2
최근 해양레포츠 산업이 블루오션으로 떠오르고 있는데, 해양레포츠는 조류, 수온, 염도 등과 같은 다양한 환경조건에 영향을 받기 때문에 관측자료 뿐만 아니라 모델 예측자료도 매우 필요한 정보이다. 본 연구에서는 연안해양모델인 FVCOM(Finite Volume Coastal Ocean Model)에서 산출된 예측자료를 웹 및 스마트폰을 통해 제공하는 시각화시스템을 구현하였다. 이를 위하여 FVCOM 자료에 내삽과 샘플링 등의 전처리를 하여, 조위, 수온, 염도의 래스터 이미지와 조류(유속, 유향)의 벡터 데이터베이스를 구축하였고, 스프링 프레임워크(Spring Framework)를 활용하여 REST(Representational State Transfer) 기반의 API(Application Programming Interface)를 제공하는 웹서비스를 구축하였다. 또한 데이터베이스 자료를 데스크톱 및 이기종의 스마트폰에 탑재시킴으로써 크로스플랫폼(cross-platform) 시각화 환경을 실현하였다. Ocean leisure sports have recently emerged as one of so-called blue ocean industries. They are sensitive to diverse environmental conditions such as current, temperature, and salinity, which can increase needs of forecasting data as well as in-situ observations for the ocean. In this context, a Web-based geovisualization system for coastal information produced by model forecasts was implemented for use in supporting various ocean activities. First, FVCOM(Finite Volume Coastal Ocean Model) was selected as a forecasting model, and its data was preprocessed by a spatial interpolation and sampling library. The interpolated raster data for water surface elevation, temperature, and salinity were stored in image files, and the vector data for currents including speed and direction were imported into a distributed DBMS(Database Management System). Web services in REST(Representational State Transfer) API(Application Programming Interface) were composed using Spring Framework and integrated with desktop and mobile applications developed on the basis of hybrid structure, which can realize a cross-platform environment for geovisualization.