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        Doxorubicin에 의한 심근증 1례

        강진무,황종문,권태찬,권치 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.2

        Doxorubicin is effective chemotherapeutic agent in the treatment of various solid tumor and hematologic malignancies. Because of its cardiotoxicity, however, early inappropriate discontinuation of doxorubicin therapy in unavoidable and may minimize its therapeutic efficacy in may patients. Doxorubicin cardoptpxicity is dose related and the cardiomyopathy is fatal in over half the cases. Authers have experienced a case of doxorubicin induced cardiomyopathy in a 4 years old girl who diagnosed dose is 345mg/M?. She also had right nephrectomy and irradiation to the right kidney area. Brief review of the literature was made.

      • 1966年度 全北金堤郡에서 報告된 類似夏季腦炎患者 豫後 및 後遺症에 關한 調査硏究

        金康湜,李煜鉉,金熔泰,鄭泰天,林就範,權致五 최신의학사 1968 最新醫學 Vol.11 No.10

        The investigation was aimed at finding out. the status of prognosis and sequelae of Japanese B type encephalitis which 'is the most serious epidemic infectious disease in Korea. Among the total 216 cases reported as encephalitis patients in Kimjae-gun, Cholla pukdo in which the largest number of encephalitis cases were reported in Korea in 1966, this survey was carried out on 201 cases whom we able to contact and examine from 6. September to 8 Sespt. 1967, about 1 year after the encephalitis epidemic 'i of 1966. The following results were obtained. 1. Case distribution by sex and age: E f,- Of the 201 cases investigated, 51.2 per cent were in male and 48.8 per cent were in female: The age group - from 3 to 7 years constituted 80.$ per cent and from 1 to 10 years constituted 96.6 per cent of cases. Susceptible I age group appeared to be in younger age group compared with those of the past encephalitis epidemics. 2. Case fatality: Case fatality rate was 36.9 per cent for male, 31.6 per cent for female and 34.3 per ' cent for total. Case . j fatality rate for male was slightly higher than that of female. 3. Frequency of sequelae by age:. j. There appeared to be no predilection by age. It was found that 50 per cent of cases of survivors had one or several kinds of sequelae. 4. Frequency of sequelae by duration between the onset and beginning of treatment: No special tendency was found by length of duration between the onset and beginning of treatment. 5. Frequency of sequelae by length of treatment: High frequency rate of sequelae was seen on the cases who treated longer which indicate more severe case.

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