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      • KCI등재

        抗 H 및 抗 H lection의 各種 動物赤血球에 對한 凝集活性에 關한比較硏究

        黃迪駿,李鳳熙,愼碩根 大韓法醫學會 1977 대한법의학회지 Vol.1 No.1

        Moon et al?? had fractionated anti-H lectin from extracts of korean Trichosanthes Kirilowii Max. and designated anti-H?? lectin because of the immunological nature of this lectin was different from anti-H lectin prepared from Ulex europeus. There-fore, this experiment was carried out for comparison the agglutination activities of anti-H?? and anti-H lectin to various animal red blood cells. Using anti-H?? lectin and anti-H lectin, prepared from korean native Trichosan-thes Kirilowii Max. and Ulex europeus, respectively, performed agglutination reaction, agglutination-inhibition test by various sugars and estimated agglutination titer with ficinized or non-ficinized cells to many kinds of animal red blood cells, and obtained with the following results: 1. The different agglutination pattern were detected in the animal red blood cells between crude extract of Trichosanthes kirilowii Max. and Ulex europeus. 2. Rabbit red blood cells were agglutinated by anti-H lectin, but not by anti-H?? lectin. 3. However, when the animal red blood cells were ficinized, rabbit cells were agglutinated by anti-H?? lectin 4. By adding L-fucose, H type specificity of anti-H lectin and Ulex extract to rabbit red cells were inhibited, while the type specificity of Trichosanthes extract were inhibited by D-galactose, L-fucose and L-lactose.

      • SCOPUSSCIEKCI등재

        후두와 종양에 대한 임상적 고찰

        신석근 대한신경외과학회 1974 Journal of Korean neurosurgical society Vol.3 No.2

        The posterior fossa, which contains about one fourth of the intracaranial contents, is the site of known about two thirds of pediatric intracranial tumors. In adults such tumors are less common and the prognosis may be very poor. However, it is important to recognize the earliest symptoms because of the relatively high ease rate of operable management and the possibility for a high cure rate in some cases. A series of 51 pathologically verified posterior fossa tumors seen at the Department of Neurosurgery, Yonsei University, Severance Hospital over several years were studied. These tumors were- explored surgically, and the diagnosis being made through histological examination. The cases were reviewed as to history, development and progression of the neurological features, laboratory findings, roentgenograms, differential diagnosis, operative methods and findings, and pathology. The author emphasized some interesting points which are illustrated as follows; 1. Among 51 cases of posterior fossa tumors, 25 cases of acoustic neuroma, 9 cases of astrocytoma, 9 cases of medulloblastoma, 2 cases of ependymoma, 3 cases of pontine glioma and 3 cases of cysticercosis in the fourth ventricle were found, comprising 21 males and 30 females. 2. The 25 operated cases of acoustic neuroma were between the age of 20 and 60. Eighteen cases (69.2%) of the remaining posterior fossa turners were below the age of 15. 3. The author was able to make the correct plain film diagnosis of acoustic neuroma in 13 cases (52%) of 25 cases. The prominent angiographic and ventriculographic finding of posterior fossa tumors was ventricular dilatation. 4. Ventriculogram was very important in the diagnosis of the fourth ventricle tumors. The Conray ventriculogram had the special benefit in accurately outlining and demonstrating the invasive pattern of fourth ventricle tumors. The Conray showed C.S.F. flow in malignant and other large tumors in the fourth ventricle better than was shown by previous pneumo-ventriculograms. 5. The Electroencephalogram showed an abnormal pattern in 62.2 per cent of 29 posterior fossa tumors.

      • 汎植物凝集素 Phaseolus vulgalis L. 의 사람 血淸에 依한 凝集阻止에 關한 硏究

        愼碩根,文國鎭 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.1

        Agglutination inhibition effects on Phaseolus vulgalis L. (P. vulgalis) was carried out with 1,223 of human sera and various sugars to understand serological characteristics of Panphytagglutinin, P. vulgalis. And demonstrated that the agglutination activity of P. vulgalis were inhibited by some sera but not by the others, and was designated the former as P. vulgalis inhibitor (PVI) and the later as P. vulgalis non-inhibitor(PVN). Frequencies of PVI and PVN were tested on 324 sera of healthy males, 197 sera of healthy females, as well as on 702 sera of patients with various pathological conditions. There were no differences in the distribution of PVI and PVN frequencies between male and female, and among ABO blood groups. The distribution of PVI was 95% (493) and PVN was 5% (28) in 521 of normal control group. A high frequency of PVN was noted in sera of the patients with gastric ulcer (38%, Z score=2.4397) and gastric cancer (25%, Z score=2.6633). No appreciable difference was noted in the frequency of PVN and PVI among patients with Duodenal ulcer, Gastro-enteritis, Liver cirrhosis, Hepatitis, Cholecystopathy, Pneumonia, Pulmonary tuberculosis, Bronchitis, Myocardiac infarction, CVA, Hypertension, Diabetes mellitus, Leukemia and Panperitonitis

      • SCOPUSSCIEKCI등재
      • SCOPUSSCIEKCI등재

        痙攣性 斜頸(Spasmodic torticollis)의 外科的 治驗 一例

        愼碩根,許琨 대한신경외과학회 1972 Journal of Korean neurosurgical society Vol.1 No.1

        The spasmodic yoricollis is the term used to describe intermittent spasmodic movement of the neck. The torticollis may occur as a sequel of epidemic encephalitis, and it is thought due to psychologic disturbance and pathological changes in basal ganglia, neostriatum, vestibular apparatus and extrapyramidal system. In the therapeutic aspect, there is no adequate treatment, yet, with various methods, including medically, psycholically and surgically. We had a case good result with surgical method that is the bilateral anterior cervical rhizotomy and subarachnoid 11th nerve section.

      • KCI등재

        장애학생 소프트웨어 교육 프로그램 적절성 탐색 연구- 희망학교 소프트웨어 교실 프로그램을 중심으로 -

        김영걸,권기홍,우정한,신석근,김형선 한국발달장애학회 2022 발달장애연구 Vol.26 No.4

        현재 우리사회는 소프트웨어 중심 사회로 변화되고 있는데, 장애학생도 사회변화에 적응하기 위해서는 SW교육이 필요하다. 이에 본 연구는 장애학생 SW교육을 위한 ‘희망학교 SW교실’에 사용된 프로그램의 적절성을 탐색하고자 하였다. 이를 위해 특수교사, 대학교수 및 ICT전문가 등 31명을 대상으로 온라인 방식을 통해 설문조사를 실시하였다. 연구의 결과는 첫째, SW교육 프로그램 내용 측면에서 ‘희망학교 SW교실’에 사용된 5개의 프로그램은 장애학생의 창의력, 입체적 사고능력, 문제해결능력, 교과학습 향상, 현실세계 체험, 컴퓨팅 사고력 및 SW교육 등에 도움이 되는 것으로 나타났다. 둘째, SW교육 프로그램 구성 측면에서 ‘희망학교 SW교실’에 사용된 5개의 프로그램은 장애학생의 특성 및 수준을 고려하여 구성할 수 있는 것으로 나타났다. 셋째, 5개 프로그램의 장점과 개선사항을 기술하였다. 그리고 이러한 결과에 기초하여 장애학생 SW교육 프로그램에 대한 시사점을 제시하였다.

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