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      • Intense red photoluminescence and mechanoluminescence from Mn2+-activated SrZnSO with a layered structure

        Zhou, Yu,Yang, Yun-Ling,Fan, Yu-Ting,Yang, Woochul,Zhang, Wei-Bin,Hu, Jian-Feng,Zhang, Zhi-Jun,Zhao, Jing-Tai The Royal Society of Chemistry 2019 Journal of Materials Chemistry C Vol.7 No.26

        <P>A series of novel red emitting Mn<SUP>2+</SUP>-activated SrZnSO phosphors were successfully synthesized by solid-state reaction at high temperature. The photoluminescence (PL) and mechanoluminescence (ML) properties of these Mn<SUP>2+</SUP>-activated SrZnSO phosphors with different Mn<SUP>2+</SUP> concentrations were investigated. With increasing the concentration of Mn<SUP>2+</SUP> from <I>x</I> = 0 to 0.04, the unit cell volume increased from 153.82 to 154.19 Å<SUP>3</SUP> while the optical band gap decreased from 3.74 to 3.43 eV. The site occupation of Mn<SUP>2+</SUP> in the host lattice was demonstrated by Rietveld refinement, the electron paramagnetic resonance (EPR) spectrum, and the spectroscopic properties. A broad band emission peak at 603 nm of SrZn1−xMnxSO (0.001 ≤ <I>x</I> ≤ 0.04) with an excitation wavelength of 318 nm was attributed to electronic transitions of Mn<SUP>2+</SUP> from the <SUP>4</SUP>T1(<SUP>4</SUP>G) level to the <SUP>6</SUP>A1(<SUP>6</SUP>S) level. The lifetime of SrZn1−xMnxSO (0.001 ≤ <I>x</I> ≤ 0.04) decreased monotonously from 2.97 to 0.82 ms with increasing Mn<SUP>2+</SUP> concentration. In particular, intense emission of red light from SrZn1−xMnxSO (0.001 ≤ <I>x</I> ≤ 0.04) under compressive load could be observed even with the naked eye, indicating that SrZn1−xMnxSO could be used for stress sensors or stress imaging. There was a linear correlation between the ML intensity and external load in SrZn1−xMnxSO, and the ML intensity could be recovered under UV light irradiation. Considering its advantages of non-destruction, reproducibility, and high ML intensity, SrZn1−xMnxSO might be useful for non-destructive detection of stress.</P>

      • KCI등재

        New Permeable Structure for Controlling Debris Flows in the Wenjiagou Gully

        Yu-feng Liang,Chuan Liang,Hongwei Zhou,Feng-rong Yang,Miao Huo,Jia-wen Zhou 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.11

        Aimed to control debris flows more effectively, we attempt to develop a new structure called a “sloping roof grill dam”, which consists of guidance walls, separation grills and lateral deposit areas. A series of flume tests were performed to verify the function of this new structure, focusing on the trapping efficiency (β ), deceleration efficiency (μ) and coarse-fine sediment separation extents (η) under different conditions of structure and debris flows. Experimental results show that both the trapping and deceleration efficiency increase with a decrease in permeability, whereas the separation extent shown the opposite effect. Multiple regression analysis indicates that β and η are linearly dependent on the permeability, deceleration efficiency and magnitudes of debris flow. In addition, an increase in beam gap can lead to an increase in the impact area downstream for the debris flow after the control of the structure. Finally, a two-level installation of the structure is tested to determine whether there is an enhancement of the debris control, which indicated that although the trapping effect of the two-level structure is considerably greater than that of a single-level structure (2.11 times at maximum), the separation extent of the two-level structure is not distinct and may be even lower.

      • Prevalence and Age, Gender and Geographical Area Distribution of Esophageal Squamous Cell Carcinomas in North China from 1985 to 2006

        Feng, Xiao-Shan,Yang, Yan-Tong,Gao, She-Gan,Ru, Yi,Wang, Gong-Ping,Zhou, Bo,Wang, Yu-Feng,Zhang, Peng-Fei,Li, Pu-Yu,Liu, Yong-Xuan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5

        Objective: To establish the prevalence and distribution profile of esophageal squamous cell carcinomas (ESCCs) over a 22-yr period in North China. Methods: Using endoscopy for primary diagnosis and histological analysis for the further confirmation, a total of 74,854 ESCC patients aged 20-89 between January 1985 and December 2006 were investigated to analyze the epidemiological profile including prevalence rates, distribution of age-of-onset, gender and geographical area of ESCC in Luoyang, the highest incidence area of North China. Results: A total of 4092 cases of ESCC were finally diagnosed among 74,854 patients who had their first endoscopies. The prevalence among males was higher than that among females (p<0.01), resulting in an overall male:female OR of 1.2 (95%CI, 1.2-1.3). The prevalence in rural areas was higher than in urban areas (p<0.01), resulting in an overall rural:urban OR of 2.6 (95%CI, 2.4-2.9). The rural:urban ORs and the 95% CI increased continuously from 2.6, 2.3-3.0 to 2.7, 2.2-3.3, respectively, for 4 consecutive periods during the 22-yr study period. Moreover, the median age of onset among females was higher than that among males (p<0.01). For both sexes and in both areas, the prevalence rates declined and the median age of onset rose for 4 consecutive periods in the 22-yrs time frame (p<0.01). Conculsions: These data reveal the epidemiological profile of ESCC in the area of North China, and suggest that urban areas and rural people account for a growing proportion of the ESCC patients although the prevalence of ESCC significantly declined and the median age-of-onset postponed over the 22-yrs period. Moreover, the prevalence status of ESCC in rural areas also underlines the need for public health initiatives aimed at reducing risk factors of this fatal disease.

      • Aberrant Expression of Markers of Cancer Stem Cells in Gastric Adenocarcinoma and their Relationship to Vasculogenic Mimicry

        Zhou, Lei,Yu, Lan,Feng, Zhen-Zhong,Gong, Xiao-Meng,Cheng, Ze-Nong,Yao, Nan,Wang, Dan-Na,Wu, Shi-Wu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10

        Background: Gastric cancer is the second leading cause of cancer-related death in Asia, and the majority type is gastric adenocarcinoma (GAC). Most GAC patients die of recurrence and metastasis. Cancer stem cells (CSCs) have been thought to be responsible for the initiation, development, metastasis, and ultimately recurrence of cancer. In this study, we aimed to investigate expression and clinical significance of CSCs markers, CD133 and Lgr5, and vasculogenic mimicry (VM) in primary GAC. Materials and Methods: Specimens from 261 Chinese patients with follow-up were analyzed for CD133, Lgr5 protein expression and VM by immunohistochemical and histochemical staining. The Pearson Chi's square test was used to assess the associations among the positive staining of these markers and clinicopathological characteristics. Postoperative overall survival time was were studied by univariate and multivariate analyses. Results: In GAC tissues, positive rates of 49.0%, 38.7%, and 26.8% were obtained for CD133, Lgr5, and VM, respectively. The mean score of microvessel density (MVD) was $21.7{\pm}11.1$ in GAC tissues. There was a significantly difference between the positive and negative groups. There was a positive relationship between the VM, the expression of CD133 and Lgr5, and the score of MVD and the grades of tumor, lymph node metastasis, TNM stages (all p<0.05). The overall mean survival time of the patients with CD133, Lgr5, VM, and MVD (${\geq}22$) positive expression was lower than that of patients with negative expression. The score of MVD, positive expression of CD133 and VM were independent prognostic factors of GAC (p<0.05). Conclusions: VM, and expression of CD133, Lgr5, and the score of MVD are related to grades of tumor, lymph node metastasis, TNM stages, and overall mean survival time. It is suggested that CSCs and VM could play an important role in the evolution of GAC.

      • KCI등재

        Protective effect of hepatocyte-enriched lncRNA-Mir122hg by promoting hepatocyte proliferation in acute liver injury

        Yu Zhenjun,Li Yuhan,Shao Shuai,Guo Beichen,Zhang Mengxia,Zheng Lina,Zhang Kun,Zhou Feng,Zhang Li,Chen Chiyi,Jiang Wentao,Hong Wei,Han Tao 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        Some long noncoding RNAs (lncRNAs), which harbor microRNAs in their gene sequence and are also known as microRNA host gene derived lncRNAs (lnc-MIRHGs), play a dominant role alongside miRNAs, or both perform biological functions synergistically or independently. However, only a small number of lnc-MIRHGs have been identified. Here, multiple liver injury datasets were analyzed to screen and identify the target lncRNA Mir122hg. Mir122hg was mainly enriched in liver tissues with human-mouse homology. In both CCl4-induced acute liver injury and Dgal/LPS-induced fulminant liver failure in mice, Mir122hg was sharply downregulated at the early stage, while a subsequent significant increase was only found in the CCl4 group with liver recovery. Overexpression and silencing assays confirmed that Mir122hg played a protective role in acute injury by promoting hepatocyte proliferation in vivo and in vitro. Consistent with the results of gene enrichment analysis, Mir122hg binding to C/EBPα affected its transcriptional repression, promoted gene transcription of downstream chemokines, Cxcl2, Cxcl3, and Cxcl5, and exerted pro-proliferative effects on hepatocytes through activation of the AKT/GSK-3β/p27 signaling pathway by CXC/CXCR2 complexes. This study identifies a novel lncRNA with protective effects in acute liver injury and demonstrates that the binding of Mir122hg-C/EBPα promotes hepatocyte proliferation via upregulation of CXC chemokine and activation of AKT signaling.

      • KCI등재

        A Passive Lossless Soft-Switching Single Inductor Dual Buck Full-Bridge Inverter

        Feng Hong,Yu Wu,Zunjing Ye,Baojian Ji,Yufei Zhou 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.2

        A novel passive lossless soft-switching single inductor dual buck full-bridge inverter (PLSSIDBFBI) is presented in this paper. To accomplish this, a passive lossless snubber circuit is added to a dual buck full-bridge inverter. Therefore, the advantages of the dual buck full-bridge inverter are included in the proposed inverter, and the inverter has just one filter inductor, which can decrease the system volume and improve the integration. In addition, the passive lossless snubber circuit achieves soft-switching by its own resonance, and all of the energy stored in the passive lossless snubber circuit can be transferred to load. A comparison between eight topologies is performed in this paper, and the analysis shows that the proposed soft-switching inverter topology has high reliability and efficiency. Finally, experimental results obtained with a 1 kW prototype verify the theoretical analysis and demonstrate the prominent characteristics of a reduced switching loss and improved efficiency.

      • KCI등재

        Entanglement Dynamics of Electron Spins in Quantum Dots Under a Nonuniform Magnetic Field

        Feng-Xue Zhou,Yi-Hong Qi,Yue-Ping Niu,Shang-Qing Gong,Jun Qian,Ting Yu,Franco Nori 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.60 No.8

        We investigate entanglement of two coupled electron spins in quantum dots (QDs) in the presence of an inhomogeneous magnetic field. The great effects of the inhomogeneous field are discussed for the dynamics of entanglement. It is shown that due to the system's symmetry, the inhomogeneity of the field does not affect the evolution of entanglement for Φ-type Bell state, while it plays a key role for Ψ-type Bell state. For the maximal entangled Bell states, the field is positive for the entanglement dynamics. The mean field can increase the entanglement revival for Φ-type Bell state while the inhomogeneous field can promote the entanglement revival for Ψ-type Bell state. For the unentangled initial states, the field is destructive for the entanglement generation induced by the coupling of the two spins.

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