http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Ruili Zhang 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10
In order to improve the performance of Support Vector Machine (SVM) classifier for imbalanced data, this paper proposes dynamic cost-sensitive SVM classifier based on chaos particle swarm optimization (CPDC_SVM). Firstly, this paper introduces dynamic cost-sensitive thought to SVM classifier, and gives the method for structuring dynamic cost and cost-sensitive SVM model. Secondly, we propose the evaluation methodology performance for classifier, and adopts decimal base to code the particles. At last, chaos thought is introduced in particle swarm optimization algorithm, and the Algorithm of the dynamic cost-sensitive SVM classifier is given, which improves convergent speed and accuracy of particle swarm optimization, and can optimize dynamic cost-sensitive SVM well, so CPDC_SVM adds effectively the convergence speed and accuracy for the particle swarm optimization algorithm. Experimental results show CPDC_SVM has higher precision than traditional SVM classifier, and dynamic cost and chaos particle swarm optimization can improve the performance for classifier.
Identification of a Small Molecule Sensitizing DNA Repair Deficiency
Yongliang Zhang,Jennifer T. Fox,Gene Elliott,Ganesha Rai,Mengli Cai,Srilatha Sakamuru,Ruili Huang,Menghang Xia,Kyeryoung Lee,Hee Dong Park,Winfried Edelmann,David Maloney,Kyungjae Myung 한국실험동물학회 2015 한국실험동물학회 학술발표대회 논문집 Vol.2015 No.8
Meishan Zhang,Ruili Lv,Wei Yang,Tiansi Fu,Bao Liu 한국유전학회 2018 Genes & Genomics Vol.40 No.1
Imprinted gene expression in flowering plants predominantly occurs in the triploid endosperm of developing seed. However, endosperm is composed of distinct tissue types. For example, the maize (Zea mays) endosperm is constituted by two major tissues, starchy endosperm and aleurone. Previous studies in imprinted gene expression have generally assumed that the different tissues constituting endosperm would behavior the same, and hence have not examined them separately. Here, to examine parentalspecific expression of imprinted genes in different parts of the seed, eight previously reported maize protein-coding imprinted genes were selected, and analyzed by cleaved amplified polymorphic sequence (CAPS) coupled with Sanger sequencing for transcripts from the various seed tissues collected at 18 days after pollination (DAP). The studied tissues included seed coat, embryo, starchy endosperm and aleurone, which were collected from a pair of reciprocal F1 hybrids produced by crossing inbred lines B73 and Mo17. Six of these eight analyzed imprinted genes showed the same imprinted expression pattern between the starchy endosperm and aleurone, but two showed imprinted expression only in the starchy endosperm. Comparison of the expression pattern of 20 selected imprinted genes in multiple seed tissues and vegetative tissues indicated that the majority (~ 75%) of these imprinted genes exhibited seedspecific or endosperm-specific expression. Our results also uncovered that imprinted genes have a high propensity to be alternatively spliced via intron retention in the developing embryo compared with the other tissues.
Fabrication of the Pesticide-Attapulgite composites regulated by mixed-surfactants
Jiexiang Liu,Ruili Bai,Xiaoguang Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.119 No.-
The SB (DTAB, TTAB, CTAB, OTAB)-AP complex was obtained by modifying attapulgite (AP) with surfactantof SB (DTAB, TTAB, CTAB, OTAB). The structures were characterized by XRD, FT-IR, TGA/DTA and SEM. A new lamellar structure is formed by introducing surfactant. The basal spacing increases with theincrease of alkyl chain length of cationic surfactants. Then, the beta-cypermethrin (BCT) composites ofBCT/SB-AP, BCT/DTAB (TTAB, CTAB, OTAB)-SB-AP were prepared and investigated. The basal spacingsof BCT composites were larger than those of SB-AP and the corresponding DTAB (TTAB, CTAB, OTAB)-AP. The existence of BCT and surfactants molecules into BCT composites was further confirmed. TheBCT/DTAB (TTAB, CTAB, OTAB)-SB-AP have the smaller specific surface areas than DTAB (TTAB, CTAB,OTAB)-AP due to the increase of AP exfoliation in the presence of SB. Fabrication mechanism of BCT compositeswas put forward. Release behaviors of BCT were investigated and analyzed in different buffersolutions. The existence of mixed-surfactants influenced distinctly the release rates. BCT compositeshad the slow release property. The release behaviors were well fitted by pseudo second-order and parabolicdiffusion models. This study provided a new approach to improve the utilization efficiency of pesticideand could be applied as a pesticide delivery system.
Yang Leilei,Fang Chengfeng,Song Caifang,Zhang Yaya,Zhang Ruili,Zhou Shenkang 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.5
BACKGROUND: Radiation enteritis (RE) is a common complication of abdominal or pelvic radiotherapy, which when severe, could be life-threatening. Currently, there are no effective treatments. Studies have shown that mesenchymal stem cells (MSCs)-derived exosomes (MSC-exos) exhibit promising therapeutic effects in inflammatory diseases. However, the specific role of MSC-exos in RE and the regulatory mechanisms remain elusive. METHODS: In vivo assay was carried out by injecting MSC-exos into the total abdominal irradiation (TAI)-induced RE mouse model. For in vitro assay, Lgr5-positive intestinal epithelial stem cells (Lgr5? IESC) were extracted from mice, followed by irradiation along with MSC-exos treatment. HE staining was performed to measure histopathological changes. mRNA expression of inflammatory factors TNF-a and IL-6 and stem cell markers LGR5, and OCT4 were quantified by RT-qPCR. EdU and TUNEL staining was performed to estimate cell proliferation and apoptosis. MiR-195 expression in TAI mice and radiation-induced Lgr5? IESC was tested. RESULTS: We found that the injection of MSC-exos inhibited inflammatory reaction, increased stem cell marker expression, and maintained intestinal epithelial integrity in TAI mice. Furthermore, MSC-exos treatment increased the proliferation and simultaneously suppressed apoptosis in radiation-stimulated Lgr5? IESC. MiR-195 expression increased by radiation exposure was decreased by MSC-exos therapy. MiR-195 overexpression facilitated the progress of RE by counteracting the effect of MSC-exos. Mechanistically, the Akt and Wnt/b-catenin pathways inhibited by MSC-exos were activated by miR-195 upregulation. CONCLUSION: MSC-Exos are effective in treating RE and are essential for the proliferation and differentiation of Lgr5? IESCs. Moreover, MSC-exos mediates its function by regulating miR-195 Akt b-catenin pathways.
Keren Jiang,Fengbin Yan,Meng Zhang,Fang Li,Donghua Li,Guirong Sun,Xiaojun Liu,Hong Li,Ruili Han,Ruirui Jiang,Zhuanjian Li,Xiangtao Kang 한국통합생물학회 2017 Animal cells and systems Vol.21 No.6
Growth factor receptor-bound protein 2 (Grb2) have been proved by a lot of studies playing a major role in cell proliferation and cell differentiation. However, the regulation of Grb2 expression by microRNAs (miRNAs) in chicken breast muscle still remains unknown. The expression profile of Grb2 was checked based on our previous RNA sequencing data and the Grb2 relative expression level in breast muscle of aged hens (55-week-old) was validated significantly higher than juvenile hens (20-week-old) using qRT-PCR. miRNAs that interact with Grb2 have been predicted in chicken and the relationship between the potential miRNA and Grb2 was verified using dual luciferase reporter assay in chicken DF1 cells. Dual-luciferase reporter assays results demonstrated that the expression of luciferase reporter gene linked with part sequence of the 3′UTR of chicken Grb2 gene was down-regulated by the overexpression of gga (Gallus Gallus)- miR-200a-3p in the DF1 cells, and the down-regulation behavior was abolished when the ggamiR- 200a-3p binding site in 3′UTR of Grb2 was mutated, indicating that gga-miR-200a can suppress the expression level of its target gene Grb2. Therefore, we concluded that the significantly increased expression level of Grb2 in the breast muscle of aged chicken can (at least partly can) be explained by the decreased expression of miR-200a, which reduced the inhibitory effect on Grb2. Taken together, these findings suggest that gga-miR-200a can suppress the expression level of its target gene Grb2 and might be involved in the cell differentiation and proliferation of chicken breast muscle through binding with the 3’UTR of Grb2.
Super-Resolution Reconstruction based on Tukey Norm and Adaptive Bilateral Total Variation
Jie Shen,Feng Xu,Mengxi Xu,Yun Yang,Ruili Wang,Lili Zhang 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.5
In Bilateral Total Variation (BTV) regularized super-resolution reconstruction (SRR), the fidelity item is only applicable to a specific noise model, and the fixed weight of BTV regularization term cannot adapt to the changes in an image. Thus, this paper proposes a SRR algorithm based on the Tukey fidelity term and adaptive BTV regularization term. The Tukey fidelity term has a more effective outliers suppression feature to deal with complex noises, and the weight of adaptive BTV regularization term can resize itself according to the changes of image textures, which can achieve the purposes of suppressing noises and preserving edges. Experimental results show that, compared with other algorithms, the proposed algorithm has better vision effects and higher Peak Signal-to-noise Ratio (PSNR) values.