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Microstructure, Thermal Conductivity and Mechanical Properties of the Mg–Zn–Sb Ternary Alloys
Yujian Huang,Xiong Zhou,Jun Du 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.11
A novel Mg alloys of Mg–xZn–ySb (x = 0, 2, 4, 6; y = 0, 0.2, 0.5, 0.8, 1.2) were designed and their microstructure, thermalconductivity and mechanical properties were systematically investigated in the present study. The as-cast Mg–Zn–Sb ternaryalloys consist of α-Mg, Mg4Zn7and Mg3Sb2phases. Sb addition can refine the eutectic structure (α-Mg + Mg4Zn7) by thegrowth of Mg4Zn7on Mg3Sb2phases. The thermal conductivity of Mg–Zn–Sb alloys decreased with increasing Sb content. There existed an interactive effect of Zn/Sb on the thermal conductivity of the Mg–Zn–Sb alloys. The negative effect of Sbaddition on thermal conductivity of alloys was getting smaller with increasing Zn content in alloys. The negative effect ofMg3Sb2phases on the thermal conductivity of alloys could be weakened by the formation of weak-scattering Mg4Zn7coatedon Mg3Sb2phases. The best refinement effect on microstructure could be obtained with 0.8 wt%Sb addition. Mg–4Zn–0.8Sballoy possess the best comprehensive properties with thermal conductivity of over than 120 W/(m·K) and UTS of 185.6 MPa.
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Fatigue Resistance of a BFRP-Encapsulated Long-Gauge FBG Strain Sensor under Cyclic Train Loads
Bi-tao Wu,Yujian Zhou,Huaxi Lu,Yunhuang Xiao,Zhenwei Zhou 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.9
To verify the performance of a basalt fiber reinforced polymer (BFRP) fiber-encapsulated long-gauge strain sensor in railway bridge health monitoring, this paper studies the fatigue resistance and durability of the BFRP fiber-encapsulated FBG sensor under train loads. First, the influences of the length of the anchorage section and the length ratio of the sensing section on the accuracy of the sensor were studied. Then, the BFRP sensor was applied to a sleeper for 2 million cycles of tension fatigue testing. The strain-time history of the whole fatigue test was monitored and compared. After the test, a calibration test was carried out to verify the accuracy and repeatability of the sensor. Finally, the slip and fatigue cracking of the fiber in the anchorage section of the sensor were observed by electron microscopy. The results show that the gap between the anchoring section and the bare optical fiber was filled with epoxy resin, and there was no slip behavior. No fatigue cracking occurred in the fiber, and the straincoefficient and linearity of the sensor showed no obvious changes after 2 million cycles of loading. The long-gauge strain sensor encapsulated by BFRP fibers exhibited good fatigue resistance and can meet long-term monitoring requirements under train loads.
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Zhikun Zhang,Ying Zhou,Jing-Kui Yang,Peilong Wang,Xiaoou Su,Hong Zhao,Yujian He,Zhiqin Cao,Maoqiang Luo 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.7
A new method has been proposed to realize the visual detection of Cr3+ using 4-nitrobenzenethiol (4-NBT) and 4-mercaptobenzoic acid (4-MBA) modified silver nanoparticles (AgNPs). The presence of Cr3+ induces the aggregation of AgNPs through cooperative metal–ligand interaction, resulting in a color change from bright yellow to purple. Consequently, Cr3+ could be monitored by colorimetric response of AgNPs by a UV-Vis spectrophotometer or even naked eyes. We firstly used ethylene diamine tetraacetic acid (EDTA) as a masking agent to selectively detect Cr3+, and other metal ions have little influence on the Cr3+–AgNPs system. The cofunctionalized AgNPs exhibited a highly sensitive detection limit of Cr3+, which is as low as 5 x 10-9 mol L-1, and the absorbance ratio (A600nm /A387nm) is linear with the concentration of Cr3+ ranging from 5 x 10-9 mol L-1 to 2 x 10-6 mol L-1 with a coefficient of 0.993. Particularly, the sensor has been further evaluated to monitor the concentration of Cr3+ in drinking water, the recovery was in good agreement with those obtained by ICP-MS, indicating that this proposed method is successfully applied in real samples.
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The role of CTNNB1 and LEF1 in feather follicles development of Anser cygnoides and Anser anser
Yue Sun,Yuxuan Zhou,Petunia Msuthwana,Jing Liu,Chang Liu,Cornelius Tlotliso Sello,Yupu Song,Ziqiang Feng,Shengyi Li,Wei Yang,Yunpeng Xu,Xiaomin Yan,Chuanghang Li,Yujian Sui,Jingtao Hu,Yongfeng Sun 한국유전학회 2020 Genes & Genomics Vol.42 No.7
Background Wingless-types/beta-catenin (Wnt/β-catenin) signaling pathway is one of the most extensively studied transcriptional cascades involved in various types of organogenesis including embryonic and postnatal development. Downy feather quantity is primarily affected by follicular development and gene regulations. Objective This research was aimed to investigate the role of catenin beta-1(CTNNB1) and lymphoid enhancerbinding factor-1 (LEF1) on feather follicles development at different developmental stages. Methods Fluorescence quantitative PCR, Western-blot and immunohistochemical methods were used in Anser cygnoides and Anser anser embryos (E12, E13 E18, and E28) and after birth gosling stages (G18, G48, G88) for gene expression analysis. Results CTNNB1 and LEF1 genes were expressed in Anser cygnoides and Anser anser at different embryonic and after-birth gosling developmental stages and the expression levels were significantly different in different stages (p < 0.05). The mRNA expression of CTNNB1 and LEF1 genes reached the highest level at D88 in Anser cygnoides, while the highest expression levels were at D18 and D88 in Anser anser, and the expression levels of CTNNB1 genes at D88 in all embryonic stages were significantly lower than after-birth stages. CTNNB1 and LEF1 protein expression were the highest at E12 and E28 for Anser cygnoides feather follicles development. While at a similar stage for Anser anser, the expression of CTNNB1 and LEF1 protein was the highest at D48 and D18. Protein expression at embryonic stages was in the epidermis (E) and the hair basal plate (P), the expression site for after-birth stages was in the dermal papilla (DP). Conclusion Our study illustrated that CTNNB1 and LEF1 has an impact on Anser cygnoides and Anser anser feather follicles growth and development.
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Yu Jian,Li Wen,Hou Guo-jun,Sun Da-peng,Yang Yuan,Yuan Sheng-xian,Dai Zhi-hui,Yin Hao-zan,Sun Shu-han,Huang Gang,Zhou Wei-ping,Yang Fu 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Hepatitis B protein x (HBx) has been reported to promote tumorigenesis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), but the mechanism awaits further investigation. In this study, we found that cFAM210A (a circular RNA derived from the third exon of transcript NM_001098801 of the FAM210A gene; CircBase ID: hsa_circ_0003979) can be silenced by HBx. cFAM210A expression was downregulated and negatively correlated with tumorigenesis in patients with HBV-related HCC. Furthermore, cFAM210A reduced the proliferation, stemness, and tumorigenicity of HCC cells. Mechanistically, HBx increased the N6-methyladenosine (m6A) level of cFAM210A by promoting the expression of RBM15 (an m6A methyltransferase), thus inducing the degradation of cFAM210A via the YTHDF2-HRSP12-RNase P/MRP pathway. cFAM210A bound to YBX1 and inhibited its phosphorylation, suppressing its transactivation function toward MET. These findings suggest the important role of circular RNAs in HBx-induced hepatocarcinogenesis and identify cFAM210A a potential target in the prevention and treatment of HBV-related HCC.
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