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      • Environmentally friendly and high performance of bamboo fiber reinforced composites

        Yue Qi,Wen-Ji Yu,Ding-Hua Ren,Yang-Lun Yu,Rong-Xian Zhu,Ya-Hui Zhang,Ya-Mei Zhang,Yu-Xiang Huang 강원대학교 산림과학연구소 2018 강원대학교 산림과학연구소 학술대회 Vol.2018 No.09

        Bamboo Fiber Reinforced Composites (BFRC), is a novel kind of engineering bamboo-based composites developed by Research Institute of Wood Industry, Chinese Academy of Forestry. This material has the advantage of controllable performance, adjustable specifications, designable structures, environmentally friendly and regeneration which makes a perfect substitute for high quality hardwood, which can be utilized in fields of flooring, furniture, interior and outdoor decoration, construction, wind turbines, and other engineering applications. The manufacturing technique of BRFC is widely promoted in many companies of 12 provinces.

      • SCOPUSKCI등재

        NaCl + CaCl<sub>2</sub> + H<sub>2</sub>O 및 KCl + CaCl<sub>2</sub> + H<sub>2</sub>O 삼성분계에 대한 50℃에서의 용해도 측정

        Yang, Ji-Min,Hou, Guang-Yue,Ding, Tian-Rong,Kou, Peng Korean Chemical Society 2010 대한화학회지 Vol.54 No.3

        NaCl-$CaCl_2$-$H_2O$와 KCl-$CaCl_2$-$H_2O$계의 용해도와 물리화학적 성질(굴절률)을 $50^{\circ}C$에서 측정하였으며, 그 결과를 상평형 그림과 조성에 따른 물리화학적 성질에 대한 도표로 나타내었다. 삼성분계의 상 평형 그림은 불변점이 하나, 일변수 곡선이 둘, NaCl (또는 KCl) 및 $CaCl_2{\cdot}2H_2O$에 대응되는 결정화 지역이 두 개가 있음을 보여주었다. 이들 계에 대하여 혼합 파라미터인 ${\theta}_{M,Ca}$와 ${\Psi}_{M,Ca,Cl}$ (M = Na or K), 평형상수 $K_{sp}$를 최소제곱법을 이용하여 결정하였으며, 이때, NaCl, KCl 및 $CaCl_2$의 단일-염 Pitzer 파라미터 ${\beta}^{(0)}$, ${\beta}^{(1)}$, ${\beta}^{(2)}$ and $C^{\Phi}$는 참고문헌을 통하여 직접 계산하였다. 이 결과들은 실험결과와 잘 일치하였다. The solubility and the physicochemical property (refractive index) in the NaCl-$CaCl_2$-$H_2O$ and KCl-$CaCl_2$-$H_2O$ systems were determined at $50^{\circ}C$ and the phase diagrams and the diagrams of physicochemical property vs composition were plotted. One invariant point, two univariant curves, and two crystallization zones, corresponding to sodium Chloride (or potassium chloride), dihydrate ($CaCl_2{\cdot}2H_2O$) showed up in the phase diagrams of the ternary systems. The mixing parameters ${\theta}_{M,Ca}$ and ${\Psi}_{M,Ca,Cl}$ (M = Na or K) and equilibrium constant $K_{sp}$ were evaluated in NaCl-$CaCl_2-H_2O$ and KCl-$CaCl_2-H_2O$ systems by least-squares optimization procedure, in which the single-salt Pitzer parameters of NaCl, KCl and $CaCl_2$ ${\beta}^{(0)}$, ${\beta}^{(1)}$, ${\beta}^{(2)}$ and $C^{\Phi}$ were directly calculated from the literature. The results obtained were in good agreement with the experimental data.

      • KCI등재

        A decade of liver organoids: Advances in disease modeling

        Yue Liu,Jian-Ying Sheng,Chun-Fang Yang,Junjun Ding,Yun-Shen Chan 대한간학회 2023 Clinical and Molecular Hepatology(대한간학회지) Vol.29 No.3

        Liver organoids are three-dimensional cellular tissue models in which cells interact to form unique structures in culture. During the past 10 years, liver organoids with various cellular compositions, structural features, and functional properties have been described. Methods to create these advanced human cell models range from simple tissue culture techniques to complex bioengineering approaches. Liver organoid culture platforms have been used in various research fields, from modeling liver diseases to regenerative therapy. This review discusses how liver organoids are used to model disease, including hereditary liver diseases, primary liver cancer, viral hepatitis, and nonalcoholic fatty liver disease. Specifically, we focus on studies that used either of two widely adopted approaches: differentiation from pluripotent stem cells or epithelial organoids cultured from patient tissues. These approaches have enabled the generation of advanced human liver models and, more importantly, the establishment of patient-tailored models for evaluating disease phenotypes and therapeutic responses at the individual level.

      • KCI등재

        Family Hilarimorphidae (Diptera) newly recorded from China with descriptions of three new species

        Liu Yue,Gao Shang,Yang Ding 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.2

        The family Hilarimorphidae is reported from China for the first time. Three new species are described and illustrated: Hilarimorpha dingae sp. nov., Hilarimorpha elongata sp. nov. and Hilarimorpha tibetensis sp. nov. A key to species of Hilarimorpha from Asia and a checklist of world species of Hilarimorphidae are provided.

      • SCIESCOPUSKCI등재

        Biotransformation of natural polyacetylene in red ginseng by Chaetomium globosum

        Wang, Bang-Yan,Yang, Xue-Qiong,Hu, Ming,Shi, Li-Jiao,Yin, Hai-Yue,Wu, Ya-Mei,Yang, Ya-Bin,Zhou, Hao,Ding, Zhong-Tao The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.6

        Background: Fermentation has been shown to improve the biological properties of plants and herbs. Specifically, fermentation causes decomposition and/or biotransformation of active metabolites into high-value products. Polyacetylenes are a class of polyketides with a pleiotropic profile of bioactivity. Methods: Column chromatography was used to isolate compounds, and extensive NMR experiments were used to determine their structures. The transformation of polyacetylene in red ginseng (RG) and the production of cazaldehyde B induced by the extract of RG were identified by TLC and HPLC analyses. Results: A new metabolite was isolated from RG fermented by Chaetomium globosum, and this new metabolite can be obtained by the biotransformation of polyacetylene in RG. Panaxytriol was found to exhibit the highest antifungal activity against C. globosum compared with other major ingredients in RG. The fungus C. globosum cultured in RG extract can metabolize panaxytriol to Metabolite A to survive, with no antifungal activity against itself. Metabolites A and B showed obvious inhibition against NO production, with ratios of 42.75 ± 1.60 and 63.95 ± 1.45% at 50 µM, respectively. A higher inhibitory rate on NO production was observed for Metabolite B than for a positive drug. Conclusion: Metabolite A is a rare example of natural polyacetylene biotransformation by microbial fermentation. This biotransformation only occurred in fermented RG. The extract of RG also stimulated the production of a new natural product, cazaldehyde B, from C. globosum. The lactone in Metabolite A can decrease the cytotoxicity, which was deemed to be the intrinsic activity of polyacetylene in ginseng.

      • Innovative displacement-based beam-column element with shear deformation and imperfection

        Yi-Qun Tang,Yue-Yang Ding,Yao-Peng Liu,Siu-Lai Chan,Er-Feng Du 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.42 No.1

        The pointwise equilibrium polynomial (PEP) element considering local second-order effect has been widely used in direct analysis of many practical engineering structures. However, it was derived according to Euler-Bernoulli beam theory and therefore it cannot consider shear deformation, which may lead to inaccurate prediction for deep beams. In this paper, a novel beam-column element based on Timoshenko beam theory is proposed to overcome the drawback of PEP element. A fifth-order polynomial is adopted for the lateral deflection of the proposed element, while a quadric shear strain field based on equilibrium equation is assumed for transverse shear deformation. Further, an additional quadric function is adopted in this new element to account for member initial geometrical imperfection. In conjunction with a reliable and effective three-dimensional (3D) corotational technique, the proposed element can consider both member initial imperfection and transverse shear deformation for second-order direct analysis of frame structures. Some benchmark problems are provided to demonstrate the accuracy and high performance of the proposed element. The significant adverse influence on structural behaviors due to shear deformation and initial imperfection is also discussed.

      • KCI등재

        Latent Classes of Circadian Type and Presenteeism and Work-Related Flow Differences Among Clinical Nurses: A Cross-Sectional Study

        Xiaofei Kang,Lijuan Yang,Linjing Xu,Yang Yue,Min Ding 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.4

        Objective To classify the characteristics of circadian type among clinical nurses and examine their relationships with presenteeism and work-related flow.Methods Using a cross-sectional design, 568 nurses were recruited through convenience sampling in January 2021 from three hospitals in Shandong Province, China. The data were collected using self-report measures, including the 11-item Circadian Type Inventory, Stanford Presenteeism Scale-6, and Work-Related Flow Inventory. Latent class analysis was performed to identify any clustering of circadian types. One-way analysis was performed to compare the differences between presenteeism and work-related flow in different circadian types.Results Four latent classes were identified, including high response class (14.4%), high flexible class (20.1%), high languid class (51.1%), and low response class (14.4%). Regarding presenteeism, the high languid class had higher scores than others. Regarding work-related flow, the scores of high flexible class were higher than those of high languid class, while the differences in all three dimensions were statistically significant.Conclusion Although the shift work mode is not expected to change, nursing managers could use circadian type as a predictive index to select and employ individuals for shift work to enhance work performance and provide sufficient support to staff who are intolerant to shift work.

      • KCI등재

        Serial Frozen Fecal Microbiota Transplantation in the Treatment of Chronic Intestinal Pseudo-obstruction: A Preliminary Study

        ( Lili Gu ),( Chao Ding ),( Hongliang Tian ),( Bo Yang ),( Xuelei Zhang ),( Yue Hua ),( Yifan Zhu ),( Jianfeng Gong ),( Weiming Zhu ),( Jieshou Li ),( Ning Li ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2017 Journal of Neurogastroenterology and Motility (JNM Vol.23 No.2

        Background/Aims Chronic intestinal pseudo-obstruction (CIPO) is a serious, life-threatening motility disorder that is often related to bacterial overgrowth. Fecal microbiota transplantation (FMT) results in restoration of the normal intestinal microbial community structure. We investigated the efficacy of FMT in the treatment of CIPO patients. Methods Nine patients (age 18-53 years) with CIPO were enrolled in this prospective, open-label study. Patients received FMT for 6 consecutive days through nasojejunal (NJ) tubes and were followed up for 8 weeks after treatment. We evaluated the rate of clinical improvement and remission, feeding tolerance of enteral nutrition, and CT imaging scores of intestinal obstructions. Lactulose hydrogen breath tests were performed before FMT and 8 weeks after FMT to evaluate for the presence small intestinal bacterial overgrowth (SIBO). Results FMT significantly alleviated bloating symptoms, and symptoms of pain were relieved 2 weeks after FMT. Enteral nutrition administered through a NJ tube after FMT was well-tolerated by 66.7% (6/9) of patients. CT scores of intestinal obstructions were significantly reduced after FMT (P = 0.014). SIBO was eliminated in 71.0% (5/7) of patients. Conclusions This pilot study demonstrated the safety of using FMT. FMT may relieve symptoms in selected patients with CIPO. FMT may also improve patient tolerance of enteral nutrition delivered via a NJ tube. (J Neurogastroenterol Motil 2017;23:289-297)

      • KCI등재

        Experimental study on seismic behavior of reinforced concrete column retrofitted with prestressed steel strips

        Bo Zhang,Yong Yang,Yuan-feng Wei,Ru-yue Liu,Chu Ding,Ke-qiang Zhang 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.55 No.6

        In this study, a new retrofitting method for improving the seismic performance of reinforced concrete column was presented, in which prestressed steel strips were utilized as retrofitting stuff to confine the reinforced concrete column transversely. In order to figure out the seismic performance of concrete column specimen retrofitted by such prestressed steel strips methods, a series of quasi-static tests of five retrofitted specimens and two unconfined column specimen which acted as control specimens were conducted. Based on the test results, the seismic performance including the failure modes, hysteresis performance, ductility performance, energy dissipation and stiffness degradation of all these specimens were fully investigated and analyzed. And furthermore the influences of some key parameters such as the axial force ratios, shear span ratios and steel strips spacing on seismic performance of those retrofitted reinforced concrete column specimens were also studied. It was shown that the prestressed steel strips provided large transverse confining effect on reinforced concrete column specimens, which resulted in improving the shearing bearing capacity, ductility performance, deformation capacity and energy dissipation performance of retrofitted specimens effectively. In comparison to the specimen which was retrofitted by the carbon fiber reinforced plastics (CFRP) strips method, the seismic performance of the specimens retrofitted by the prestressed steel strips was a bit better, and with much less cost both in material and labor. From this research results, it can be concluded that this new retrofitting method is really useful and has significant advantages both in saving money and time over some other retrofitting methods.

      • KCI등재

        JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis

        Li Xie,Hui Chen,Li Zhang,Yue Ma,Yuan Zhou,Yong-Yu Yang,Chang Liu,Yu-Li Wang,Ya-Jun Yan,Jia Ding,Xiao Teng,Qiang Yang,Xiu-Ping Liu,Jian Wu 대한간학회 2024 Clinical and Molecular Hepatology(대한간학회지) Vol.30 No.2

        Background/Aims: Cholestatic liver diseases including primary biliary cholangitis (PBC) are associated with active hepatic fibrogenesis, which ultimately progresses to cirrhosis. Activated hepatic stellate cells (HSCs) are the main fibrogenic effectors in response to cholangiocyte damage. JCAD regulates cell proliferation and malignant transformation in nonalcoholic steatoheaptitis-associated hepatocellular carcinoma (NASH-HCC). However, its participation in cholestatic fibrosis has not been explored yet. Methods: Serial sections of liver tissue of PBC patients were stained with immunofluorescence. Hepatic fibrosis was induced by bile duct ligation (BDL) in wild-type (WT), global JCAD knockout mice (JCAD-KO) and HSC-specific JCAD knockout mice (HSC-JCAD-KO), and evaluated by histopathology and biochemical tests. In situ-activated HSCs isolated from BDL mice were used to determine effects of JCAD on HSC activation. Results: In consistence with staining of liver sections from PBC patients, immunofluorescent staining revealed that JCAD expression was identified in smooth muscle α-actin (α-SMA)-positive fibroblast-like cells and was significantly up-regulated in WT mice with BDL. JCAD deficiency remarkably ameliorated BDL-induced hepatic injury and fibrosis, as documented by liver hydroxyproline content, when compared to WT mice with BDL. Histopathologically, collagen deposition was dramatically reduced in both JCAD-KO and HSC-JCAD-KO mice compared to WT mice, as visualized by Trichrome staining and semi-quantitative scores. Moreover, JCAD deprivation significantly attenuated in situ HSC activation and reduced expression of fibrotic genes after BDL. Conclusions: JCAD deficiency effectively suppressed hepatic fibrosis induced by BDL in mice, and the underlying mechanisms are largely through suppressed Hippo-YAP signaling activity in HSCs.

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