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      • Knowledge Acquisition Approach Based on Rough Set in Online Aided Decision System for Food Processing Quality and Safety

        Liu Peng,Liu Wen,Li Qiang,Yang Li,Duan Min,Dai Yue 보안공학연구지원센터 2014 International Journal of u- and e- Service, Scienc Vol.7 No.6

        For the problem that the use effect of food processing information system is poor due to absence of knowledge acquisition measures and knowledge self-updating function, a knowledge acquisition approach based on rough set is put forward. First, the approach establishes a set of predicted samples for the relationship between food processing parameters and product quality; then uses the discretization of continuous attribute, attribute reduction and rule extraction algorithm of rough set to acquire automatically predicted knowledge from a large number of predicted sample sets, and then saves the predicted knowledge in the knowledge base of expert system; finally, realizes the extraction of knowledge of food processing process based on the inference engine, which greatly enhances the effectiveness and practicality of the acquired knowledge in online aided decision system of the food processing quality and safety.

      • KCI등재

        The role of CTNNB1 and LEF1 in feather follicles development of Anser cygnoides and Anser anser

        Yue Sun,Yuxuan Zhou,Petunia Msuthwana,Jing Liu,Chang Liu,Cornelius Tlotliso Sello,Yupu Song,Ziqiang Feng,Shengyi Li,Wei Yang,Yunpeng Xu,Xiaomin Yan,Chuanghang Li,Yujian Sui,Jingtao Hu,Yongfeng Sun 한국유전학회 2020 Genes & Genomics Vol.42 No.7

        Background Wingless-types/beta-catenin (Wnt/β-catenin) signaling pathway is one of the most extensively studied transcriptional cascades involved in various types of organogenesis including embryonic and postnatal development. Downy feather quantity is primarily affected by follicular development and gene regulations. Objective This research was aimed to investigate the role of catenin beta-1(CTNNB1) and lymphoid enhancerbinding factor-1 (LEF1) on feather follicles development at different developmental stages. Methods Fluorescence quantitative PCR, Western-blot and immunohistochemical methods were used in Anser cygnoides and Anser anser embryos (E12, E13 E18, and E28) and after birth gosling stages (G18, G48, G88) for gene expression analysis. Results CTNNB1 and LEF1 genes were expressed in Anser cygnoides and Anser anser at different embryonic and after-birth gosling developmental stages and the expression levels were significantly different in different stages (p < 0.05). The mRNA expression of CTNNB1 and LEF1 genes reached the highest level at D88 in Anser cygnoides, while the highest expression levels were at D18 and D88 in Anser anser, and the expression levels of CTNNB1 genes at D88 in all embryonic stages were significantly lower than after-birth stages. CTNNB1 and LEF1 protein expression were the highest at E12 and E28 for Anser cygnoides feather follicles development. While at a similar stage for Anser anser, the expression of CTNNB1 and LEF1 protein was the highest at D48 and D18. Protein expression at embryonic stages was in the epidermis (E) and the hair basal plate (P), the expression site for after-birth stages was in the dermal papilla (DP). Conclusion Our study illustrated that CTNNB1 and LEF1 has an impact on Anser cygnoides and Anser anser feather follicles growth and development.

      • A New Static Data Flow Clustering Algorithm for Task Scheduling of Irregular Mesh in NoCs Based on Complex Networks

        Yue Liu,MengMeng Cao,Kong Jie 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.9

        The majority of recent embedded systems are based on MPSoCs (Multi-Processors System on Chip) architectures. The topologies and the interconnections inside multi processors almost adopt NoCs (Networks on Chip) whose topology and task scheduling algorithm have a direct impact on its performances. In this paper, by using static data flow, a task scheduling algorithm which would automatically assign the application tasks onto different processors is proposed based on complex network. The goal of our algorithm is to replace the static data flow subnetwork by a single dynamic data flow actor such that the global performance in terms of latency and throughput is optimized. Through complex network, it greatly enhances the power of our algorithm in terms of avoiding deadlock, saving energy and providing for integration with more general models of computation. Experimental results show up to 60% performance improvement for real-world examples.

      • KCI등재

        ≪聊斋志异≫的政治寓托与政治观照

        LIU Yue-hui(刘跃辉),Go Bee(高飛) 한국문화융합학회 2019 문화와 융합 Vol.41 No.5

        The study of the history of Chinese literature has always had the tendency to disregard historical evidence or to be one-sided, especially the study of Pu Songling and his work, Strange Tales of Liao-Zhai. Based on historical evidence, this article makes a detailed textual research analysis of Pu Songling’s family background and the course of the imperial examination. The article holds that Pu Songling’s success in the imperial examination when he was young and his later self-indulgence by seeking the ancient route and deviating from the path and goal of the imperial examination are the main reasons for his ultimate failure in the examination and his complete disconnection from his official career. However, Pu Songling had a strong sense of self, preserved his mind, indulged his feelings, and was satisfied with life in the countryside. Moreover, he had a clear self-cognition and was not addicted to imperial examinations. He inherited the tradition of Chinese literati since the Pre-Qin dynasty, which involved paying attention to themselves and their lives. His Strange Tales of Liao-Zhai is a collection of literature and thoughts based on humanity in the late Ming dynasty, which is a reverse extension of self-consciousness development in other places from the suppression of the early Qing society. The book is full of praise for people in the world and for true love and the simple concept of equality, which is intended to benefit Confucianism and political rule, hoping to use Taoism to help the world, and to put forward political views on the basis of the people. In the dull literary world of the early Qing dynasty, this book was a dazzling brilliance of human nature. 中国文学史研究,历来有脱离史证形而上的倾向,对蒲松龄与≪聊斋志异≫的研究尤为如此。 文章立足史证,对蒲松龄家世背景与科考历程进行了细致考辨,认为蒲松龄少年科场得志,随性纵情,旁求古道,不务科考,是其屡试不第,仕途中绝的主要原因。 蒲松龄有着强烈的自我意识,率性纯真,全性任情,悠然于田园之间,他有着清醒的自我认知,未尝沉迷于科场。 蒲松龄继承了先秦以来中国文人关注自我、 关注生活的传统,他创作的≪聊斋志异≫,是明末“人”的文学与思想的集大成者,是自我意识发展在清初社会受到压制,而在“他界”的逆向伸展。 书中充满了对人与人世的赞美与肯定、 对真情真爱的歌颂以及朴素的平等观念,意求“有功名教”、 以道济世,以“人”为中心对现实社会提出政治观照。 在清初沉闷的文坛中,闪出了耀眼的人性光辉。

      • KCI등재

        An improved resonantly driven piezoelectric gas pump

        Yue Wu,Yong Liu,Jian-Fang Liu,Long Wang,Xiaoyang Jiao,Zhigang Yang 대한기계학회 2013 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.27 No.3

        Piezoelectric pumps have the potential to be used in a variety of applications, such as in air circulation and compression. However, piezoelectric membrane pumps do not have enough driving capacity, and the heat induced during the direct contact between the driving part and the gas medium cannot be dissipated smoothly. When the gas is blocked, the piezoelectric vibrator generates heat quickly, which may eventually lead to damage. Resonantly driven piezoelectric stack pumps have high performance but no price advantage. In this situation, a novel, resonantly driven piezoelectric gas pump with annular bimorph as the driver is presented. In the study, the working principle of the novel pump was analyzed, the vibration mechanics model was deter-mined, and the displacement amplified theory was studied. The outcome indicates that the displacement amplification factor is related with the original displacement provided by the piezoelectric bimorph. In addition, the displacement amplification effect is related to the stiffness of the spring lamination, adjustment spring, and piezoelectric vibrator, as well as to the systematic damping factor and the driving frequency. The experimental prototypes of the proposed pump were designed, and the displacement amplification effect and gas output performance were measured. At 70 V of sinusoidal AC driving voltage, the improved pump amplified the piezoelectric vibrator displacement by 4.2 times, the maximum gas output flow rate reached 1685 ml/min, and the temperature of the bimorph remained normal after 2000 hours of operation when the gas medium was blocked.

      • Expression and Clinical Significance of mTOR in Surgically Resected Non-small Cell Lung Cancer Tissues: a Case Control Study

        Liu, Zhe,Wang, Liang,Zhang, Li-Na,Wang, Yue,Yue, Wen-Tao,Li, Qi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

        Aims: Mammalian target of rapamycin (mTOR) is master regulator of the PI3K/Akt/mTOR pathway and plays an important role in NSCLCs. Here we characterized mRNA and protein expression levels of mTOR and its functional associated molecules including PTEN, IGF-1R and 4EBP1 in surgically resected NSCLCs. Methods: Fifty-four patients with NSCLCs who underwent pulmonary resection were included in current study. mRNA levels of mTOR, PTEN, IGF-1R, and 4EBP1 were evaluated by RT-PCR and protein expression of mTOR, PTEN, and IGF-1R by immunohistochemistry (IHC). Association of expression of the relevant molecules with clinical characteristics, as well as correlations between mTOR and PTEN, 4EBP1 and IGF-1R were also assessed. Results: The results of RT-PCR showed that in NSCLCs, the expression level of mTOR increased, while PTEN, 4EBP1 and IGF-1R decreased. Statistical analysis indicated high IGF-1R expression was correlated with advanced clinical stage (stage III) and PTEN expression was reversely associated with tumor size (P=0.16). The results of IHC showed mTOR positive staining in 51.8% of cases, while IGF-1R positive staining was found in 83.3% and loss of PTEN in 46.3%. Protein expression of mTOR was correlated with its regulators, PTEN and IGF-1R, to some extent. Conclusions: Abnormal activation of mTOR signaling, high expression of IGF-1R, and loss of PTEN were observed in resected NSCLC specimens. The poor expression agreement of mTOR with its regulators, PTEN, and IGF-1R, implied that combination strategy of mTOR inhibitors with other targets hold significant potential for NSCLC treatment.

      • KCI등재

        Simultaneous Determination of Hydroquinone and Catechol by N-doped Porous Biochar-modified Electrode

        Yue-Xin Liu,Shi-Man Du,Jie Cao,Wen-sheng Huang,Xiao-Ru Zhang,Bao-Ping Qi,Sheng-Hui Zhang 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.3

        N-doped porous biochar (NPB) with large conjugated systems could not only be used as enrichment carriers but also be in favor of electron transport in the electrochemical detection. The NPB-modified electrode was fabricated for the simultaneous detection of catechol (CA) and hydroquinone (HQ) to enhance the signal-to-noise ratio and further improve the sensitivity. A detection limit as low as 37 and 47?nM was achieved for CA and HQ, respectively. The proposed strategy with the merits of high sensitivity, selectivity, and reproducibility exhibited a great potential for the detection.

      • Fenofibrate Increases Radiosensitivity in Head and Neck Squamous Cell Carcinoma via Inducing G2/M Arrest and Apoptosis

        Liu, Jia,Ge, Yang-Yang,Zhu, Hong-Cheng,Yang, Xi,Cai, Jing,Zhang, Chi,Lu, Jing,Zhan, Liang-Liang,Qin, Qin,Yang, Yan,Yang, Yue-Hua,Zhang, Hao,Chen, Xiao-Chen,Liu, Zhe-Ming,Ma, Jian-Xin,Cheng, Hong-Yan,S Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

        Radiation therapy is an important treatment for head and neck squamous cell carcinoma (HNSCC). However, how to promote radiation sensitivity in HNSCC remains a challenge. This study aimed to investigate the radiosensitizing effects of fenofibrate on HNSCC and explore the underlying mechanisms. HNSCC cell lines CNE-2 and KB were subjected to ionizing radiation (IR), in the presence or absence of fenofibrate treatment. Cell growth and survival, apoptosis and cell cycle were evaluated. In addition, CNE-2 cells were xenografted into nude mice and subjected to IR and/or fenofibrate treatment. The expression of cyclinB and CDK1 was detected by Western blotting. Our results showed that fenofibrate efficiently radiosensitized HNSCC cells and xenografts in mice, and induced apoptosis and G2/M arrest via reducing the activity of the CDK1/cyclinB1 kinase complex. These data suggest that fenofibrate could be a promising radiosensitizer for HNSCC radiotherapy.

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