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CordDial: Usability study about new enhanced TUI with elastic feedback for mobile platform
Youngeun Song,Ian Oakley 한국HCI학회 2018 한국HCI학회 학술대회 Vol.2018 No.1
While commercial Tangible User Interfaces (TUI) based on capacitive touch screen has appeared, exploring its usability is one of important research area. Thus, we explored usability of TUI on a tablet using Fitts’ law. Our study compared multi-touch input, commercial TUI, and a TUI enhanced with an elastic cord that provides passive haptic feedback, during interaction on a tablet with five representative spanning movement tasks; pull, cross, bend, slide, and rotation. We run this empirical study with 13 participants and gathered throughput, error rate, and subjective ratings (NASA TLX) about combination of each input and task. Our result shows the TUI with the cord decrease overall performance for the bend task. Our work contributes finding new empirical data highlight performance variations between multi-touch and TUI, and suggesting novel TUI with an elastic cord for providing passive haptic feedback.
『한역도행구경(漢譯道行究竟)』을 통해 본 마덕신(馬德新)의 중국적 이슬람 이해
송영은(Youngeun SONG) 한국종교학회 2020 宗敎硏究 Vol.80 No.3
Indigenous interpretative traditions of Islam has been widely developed since 17<SUP>th</SUP> century in China, with the great efforts of Chinese muslim scholars to interpret Islam through chinese language and traditions. As a result, we could see Confucianistic muslim scholar like Liu Zhi (劉智) who reconstruct Chinese Islamic worldview through Islamic mystical philosophy and neo-confucianistic way of thinking, as well as muslim scholars who put more stress on the original languages and meanings of Islam. In this paper, we focus on one of the great muslim scholars of Yunnan, Ma Dexin(馬德新) who had been also a leading figure of Yunnan panthay rebellion in 19<SUP>th</SUP> century. Ma had been experiencing new tendencies claiming to return to fundamental faith of Islam. And at the same time, he had been struggling to set new identities of Yunnan Muslims to overcome severe conflicts between majority Han zu(漢族) and minority Yunnan muslims after rebellion. Based on these circumstances, Ma’s Chinese translation of Maqṣad-i Aqṣā(the furthest goal), that is Daoxingjiujing 『道行究竟』was chosen to seek his own understanding on Chinese Islam. In his translaton Ma divided the text into two parts and chose completely different methods to convey their meanings. These different approaches are to be considered to co-relate Islamic worldview in original text with Liu Zhi’s indigenous interpretation of Islam. And analysis on technical terms in persian texts and its chinese translations are regarded to show Ma’s unique understanding of Chinese Islam.
Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability
Kim, Youngeun,Kim, Wantae,Song, Yonghee,Kim, Jeong-Rae,Cho, Kyungjoo,Moon, Hyuk,Ro, Simon Weonsang,Seo, Eunjeong,Ryu, Yeon-Mi,Myung, Seung-Jae,Jho, Eek-Hoon National Academy of Sciences 2017 Proceedings of the National Academy of Sciences Vol.114 No.18
<P>Hippo signaling controls the expression of genes regulating cell proliferation and survival and organ size. The regulation of core components in the Hippo pathway by phosphorylation has been extensively investigated, but the roles of ubiquitination-deubiquitination processes are largely unknown. To identify deubiquitinase(s) that regulates Hippo signaling, we performed unbiased siRNA screening and found that YOD1 controls biological responses mediated by YAP/TAZ. Mechanistically, YOD1 deubiquitinates ITCH, an E3 ligase of LATS, and enhances the stability of ITCH, which leads to reduced levels of LATS and a subsequent increase in the YAP/TAZ level. Furthermore, we show that the miR-21-mediated regulation of YOD1 is responsible for the cell-density-dependent changes in YAP/TAZ levels. Using a transgenic mouse model, we demonstrate that the inducible expression of YOD1 enhances the proliferation of hepatocytes and leads to hepatomegaly in a YAP/TAZ-activity-dependent manner. Moreover, we find a strong correlation between YOD1 and YAP expression in liver cancer patients. Overall, our data strongly suggest that YOD1 is a regulator of the Hippo pathway and would be a therapeutic target to treat liver cancer.</P>
JaeMin Song,YoungEun Jung,JoonHyuk Park,MoonDoo Kim,MinSeok Cheon,ChangIn Lee 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.4
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is associated with severe skin eruptions, fever, hematological abnormalities, and multi-organ involvement. Although aromatic anticonvulsant drugs have been frequently associated with the manifestation of DRESS syndrome, its induction following treatment with nonaromatic anticonvulsants, such as valproate, has rarely been reported. Moreover, there are limited data regarding the development of neosensitization related to chemically unrelated drugs following an episode of DRESS syndrome. Here, a case of neosensitization to multiple drugs is described. The present case report describes a female patient who experienced neosensitization to amoxicillin, olanzapine, and quetiapine following the manifestation of DRESS syndrome induced by valproate.