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Neurite Guidance on Laser-Scribed Reduced Graphene Oxide
Lee, Sang Hwa,Lee, Han Byeol,Kim, Yoonyoung,Jeong, Jae Ryeol,Lee, Min Hyung,Kang, Kyungtae American Chemical Society 2018 NANO LETTERS Vol.18 No.12
<P>This paper describes a one-step, chemical-free method to generate micropatterned in vitro neuronal networks on chemically unmodified reduced graphene oxide. The suggested method relies on infrared-based photothermal reduction of graphene oxide, which concurrently leads to the formation of submicrometer-scale surface roughness that promotes neuronal adhesion and guides neurite outgrowth. A commercially available laser source (LightScribe DVD drive) controlled by a computer software can be used to reduce graphene oxide (GO), and its repetitive scribing to a GO film brings about gradual increase and decrease in electrical conductivity and neurite guiding ability of the scribed regions, respectively. Our results also indicate that the observed adhesion-promoting and neurite guiding effect originate from the contrast in surface nanotopography, but not that in conductivity. This method is readily applicable to diverse graphene-based biomedical devices.</P> [FIG OMISSION]</BR>
이윤영(Yoonyoung Lee) 한국주거환경학회 2024 주거환경(한국주거환경학회논문집) Vol.22 No.1
This study empirically analyzes the determinants of apartment sale prices in the auction market, focusing on apartments auctioned in Daegu as of 2021. Specifically, it aims to examine whether various factors based on regional characteristics influence sale prices and to explore the detailed impact of residential density. The main empirical findings are as follows. Auction characteristics were all significant. Forced auctions and the number of bidders increased sale prices, while the number of unsuccessful bidders and unpaid management fees decreased sale prices. In terms of Characteristics of goods, the construction period, parking spaces per household, and small and medium-sized area showed significant results. The elapsed years reduced sale prices, while parking spaces per household and small and medium-sized area increased sale prices. In terms of location characteristics, subway distance and school distance were significant. However, it was analyzed that the influence on sales prices was very low. Finally, the study looked at the impact of residential amenities, which hadn't been considered before. Over half of the sub-variables showed significance. Dense residential areas were found to increase sale prices, indicating a preference for housing with various amenities. The results of this study confirmed the determinants of apartment auction sale prices. Specifically, it was established that dense residential areas yield high sale prices in the auction market, attributed to their relatively superior amenities. This study suggests that equal amenities are needed to stabilize the prices of local housing markets.
이윤영(Yoonyoung Lee) 한국배움학회 2011 배움학 연구 Vol.3 No.2
이 연구는 국제결혼가정 자녀들의 수업 중 배움을 저해하는 요인이 무엇인지 알아보는 연구이다. 국제결혼가정 자녀들의 배움을 저해하는 요인을 학습자 중심으로 살펴보고 그들의 배움을 실질적으로 도울 필요가 있다. 이를 통해 국제결혼가정 자녀들의 자발적 배움력을 기르고, 이들을 지도하는 초등학교 교사들의 효과적인 학습지도에 실질적인 도움을 주는데 연구의 목적이 있다. 국제결혼 가정 자녀의 배움을 저해하는 수업 내적 요인은 교사에 대한 관심과 지지의 요구, 수업 외적 요인은 '어머니의 부재(不在)'와 '어머니가 주는 과중한 학습부담', 또래 요인인 놀림과 따돌림이었다. 연구를 통해 세 가지의 결론을 얻었다. 첫째, 국제결혼가정 자녀들의 수업을 적극적으로 도울 보조교사의 배치와 국제결혼가정 자녀들의 학교생활에서의 어려움 해결을 도울 전문상담교사의 배치가 필요하다. 둘째, 국제결혼가정 자녀 개개인의 가정환경을 고려한 맞춤형 대안 수립 및 지원과 이중 언어 교육을 위한 단계별 원격 화상 강의 시스템 제공 등의 교육 정책적 지원이 필요하다. 셋째, 다문화가정자녀들의 올바른 성장과 국가인적자원 개발을 위해 국가가 지원하는 지역사회 중심 다문화가정자녀 전담보육시설의 설립 및 운영이 필요하다. This study aims to investigate the restraints on erudition of learners in the classes of the children from international marriage family. It is necessary to help their study by identifying the restraints, that has increasingly expanded, on erudition of them in the perspective of learners. This study aims to cultivate spontaneous erudition capability of them and to provide practical help to the elementary school teachers for their effective teaching. As for the internal factors that restrained erudition of the children from international marriage, the absence of mother, the excessive burden from mother for erudition and derision and bullying from the same age group, were analyzed. Firstly, in order to help the erudition of the children from international marriage, the improvement of educational environment is required. The distribution of specialized teachers who can help the children is required. Secondly, in order to remove the factors that restrain the erudition of the children from international marriage, the improved policies for the new education is required. Thirdly, for the desirable growth of the children from multicultural families and the development of national human resources, the establishment and operation of the child care facilities supported by the state, are required.
성인당뇨환자의 비외과적 치주치료에 의한 구강건강상태 개선에 따른 삶의 질 변화
최윤영 ( Yoonyoung Choi ),이재영 ( Jaeyoung Lee ),이희영 ( Heeyoung Lee ),진보형 ( Bohyoung Jin ) 대한예방치과·구강보건학회 2015 大韓口腔保健學會誌 Vol.39 No.3
Objectives: The aim of this study was to investigate changes in the quality of life and oral health status in diabetic patients as a result of non-surgical periodontal treatments. Methods: In total, 55 diabetic patients who visited the health care center at our institution participated in this study. The patients were divided randomly into 3 groups as follows: scaling and root planning (SRP), professional maintenance care (PMC), and control (CT). The patients were asked to answer the Short- Form-36 Health Survey (SF-36) to evaluate their quality of life, and two examiners evaluated the patients’ oral health status before and after the periodontal treatments. To evaluate the oral health status, the current number of teeth, DMFT index, bleeding on probing rate (BOP), pocket depth (PD), and calculus index (CI) were used. Statistical analyses were conducted using SPSS with appropriate sampling weights to adjust for the stratified sample design. Results: In both the SRP and PMC groups, the BOP and CI decreased after the treatment (P<0.05). In the SRP group, physical functioning and the mental health score increased (P<0.05). Conclusions: According to the results, non-surgical periodontal treatment in diabetic patients is effective in increasing the health-related quality of life.
Jang, Yoonyoung,Choi, Yoon-Jung,Lim, Youn-Hee,Lee, Kyung-Shin,Kim, Bung-Nyun,Shin, Choong Ho,Lee, Young Ah,Kim, Johanna Inhyang,Hong, Yun-Chul The Korean Society for Preventive Medicine 2021 예방의학회지 Vol.54 No.1
Objectives: Bisphenol A (BPA) is used in the electrical, mechanical, medical, and food industries. Previous studies have suggested that BPA is an endocrine disruptor. Regulation of BPA has led to increased use of bisphenol F (BPF) and bisphenol S (BPS). However, few studies have investigated the associations of BPF and BPS with thyroid dysfunction in children. Our study investigated the associations of prenatal BPA and early childhood BPA, BPF, and BPS exposure with thyroid function in 6-year-old children. Methods: Prenatal BPA concentrations were measured during the second trimester of pregnancy in an established prospective birth cohort. We measured urinary BPA, BPF, and BPS concentrations and thyroid hormone levels (thyroid-stimulating hormone, total T3, and free T4) in 6-year-old children (n=574). We examined the associations between urinary bisphenol concentrations and percentage change of thyroid hormone concentrations using multivariate linear regression. We also compared thyroid hormone levels by dividing the cohort according to BPA, BPF, and BPS concentrations. Results: The associations between prenatal BPA and total T3 levels were statistically significant in all models, except for girls when using a crude model. The associations between urinary BPA and BPS concentrations and levels of all thyroid hormones were not statistically significant. However, we observed that lower free T4 levels (-1.94%; 95% confidence interval, -3.82 to -0.03) were associated with higher urinary BPF concentrations in girls only. Conclusions: Our findings identified significant associations between prenatal BPA exposure and total T3 levels in all children and between BPF exposure and free T4 levels in girls only.
Jin Gyun Lee,Sang-yeon Shin,Hae-jin Shin,Yoonyoung Huh,이슬지,Dong-Hwan Kim,Sujung Lee,Young-Ok Kim,한상범,이정미,박정일,권성원 한국약제학회 2012 Journal of Pharmaceutical Investigation Vol.42 No.1
High performance liquid chromatography–ultraviolet (HPLC–UV) detection method was performed to simultaneously determine three preservatives: cresol,chlorocresol and benzethonium. According to the current Korean Pharmacopeia Codex, the only-available analytical method for discerning the three preservatives uses thinlayer chromatography, which does not provide accurate detection or quantification. Therefore, this study focused on developing a new HPLC–UV method which gives fast,accurate and sensitive outcomes. The experiment was done using Phenomenex Gemini column [C18 (250 9 4.6 mm,5 lm)] and the mobile system was methanol and 0.01 M potassium phosphate (monobasic) in water (pH = 3.3). The developed method was validated through linearity,range, system suitability, precision, accuracy, recovery and inter-laboratory variation.