혈행화된 두개골 피판을 이용한 안와저 및 안와하연의 재건술 치험례

정윤규,이훈범,김석원,봉정표,김균태,김주봉 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.5

A number of methods have been introduced for support the orbital floor following a maxillectomy without orbital exenteration or severe facial trauma. These methods including skin graft and muscular sling provided the unsatisfactory results, like as diplopia, orbital ptosis, enophthalmos and severe facial deformity. Therefore the bone and soft tissue reconstructions using microvascular free flaps were performed recently by many surgeons, but long time operation, donor site morbidity, postoperative large scar, and ptosis of the flap were pointed out as disadvantages of free flap reconstruction. Vascularized calvarial bone flap, a modified method of free calvarial bone graft, was adequate for reconstruction of the orbital floor and the infraorbital rim as a horizontal buttress, especially in case of poor vascular bed and postradiated state. The authors introduced the vascularized calvarial bone flap for the orbital floor and the infraorbital rim reconstruction in 3 cases of maxillectomy, and could be obtained satisfactory results aesthetically and functionally.

L-Asparaginase가 Mouse의 肝細胞에 미치는 影響

鄭鎬三,李圭植,尹康默 한양대학교 의과대학 1985 한양의대 학술지 Vol.5 No.1

L-asparaginase hydrolysis L-asparagine which is essential amino acid for tumor cells to produce an antitumorous effect. On the other hand, it was reported that this drug provoked cytotoxic effect following the inhibition of protein synthesis and that this was a consequence of the exhaustion of L-asparagine in the normal cell. Therefore, the authors have demonstrated the toxicity of L-asparaginase on the hepatic parenchymal cell observing with light and electron microscope: Male mice of ICR strain were used in this experiment and the weight of experimental animals was around 20gm. The animals were divided into two groups, the control and the L-asparaginase treated groups and subdivided into the 6th, 12th and 24th hours groups. L-asparaginase 2,500 I.U./kg, in the water for injection was injected intraperitoneally for the animals of L-asparaginase treatment group. The animals of control group were given water for injection only. The experimental animals were sacrificed at the 6,12 and 24 hours after an administration of L-asparaginase or water for injection. The liver specimens were stained with hematoxylin oesin, methyl green-pyronin and oil red 0 method and observed them under the light microscope. And the ultrathin sectioned specimens were stained with uranyl acetate and lead citrate and observed with the JEM 100B electron microscope. The results obtained were as follows: 1. Cellular swelling accompanied with the vesicular or vacuolar formation, reduction or disappearance of the pyroninophilic granules and fat infiltration were observed in the hepatic parenchymal cells of the L-asparaginase treated mouse. 2. Dilatation, sacculation and fragmentation of the cisternae of RER were accompanied with dissociation of membrane bound ribosomes, and proliferation of SER associated with depletion of glycogen particles were observed. And formation of numerous primary lysosomes, secondary lysosomes, autophagic vacuoles, multivesicular bodies and irregular sized lipid droplets were recognized in the hepatic parenchymal cells of the L-asparaginase treated mouse. Consequently, it is suggested that intraperitoreal injection of L-asparaginase would include the cellular degeneration of the hepatic parenchymal cells in the mouse.

고등학교 지구과학 실험·실습 요목 비교 분석

정원우,이윤종,기우항,김영호,양승영,강용희,안병호,임성규,윤일희,김중욱,윤성효,강동진 경북대학교 과학교육연구소 1997 科學敎育硏究誌 Vol.21 No.-

The purpose of this study is to investigate the status of the experimental and practical education in high school earth. The present status and reasonable management of the experimental and practical education in high school earth science have been grasped from the questionaires. To do this, eighty eight earth science teachers in Korea are administered questionaires. The frequency of the experimental and practical items in the seven kind of earth science text books were investigated. The problems and the reasonable management for experimental and practical education were proposed in this paper.

현행 중학교 과학 실험·실습교육에 대한 교사들의 견해와 개선방안

이윤종,기우항,김영호,정원우,양승영,강용희,안병호,임성규,윤일희,김중욱,강동진 경북대학교 과학교육연구소 1996 科學敎育硏究誌 Vol.20 No.-

The status of facilities, management of the experiment, practices, and Science education teaching method in middle school have been investigated. The present status and reasonable management of middle school science education have been grasped from the questionaires. The results are as follows : The reasonable management for expeiments and practices of science education were scanty in the middle school around the urban and rural schools owing to the shortage of facilities and equipments, crowded class, excessive classes, work for teachers, excessive contents of present textbook and insufficience of administrative support etc. The current teaching method of middle school science has emphasized knowledge. This fact does not satisfy the objective of learning due to lack of teaching method. Desirable directions for the improvement of present status of middle school science education were proposed in this paper.

하지 절단자 보행의 운동역학적 분석

임규찬,박윤서,배성제,정철수,신인식,김복영 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

This study was conducted to investigate the biomechanical characteristics of the gait pattern in an amputee for the purpose of improving the proper gait posture and designing the prosthetic. The subjects were six males amputees and one normal person. The ground reaction force was measured using AMTI force platform. The conclusions were as follows; 1. In case of amputee group, the ground reaction force was revealed in specific figure according to position in which they used the prosthetic, whereas in case of normal person the ground reaction force was revealed in the figure of two humps in regard of vertical axis. 2. In case of amputee group, the ground reaction force in time between fight foot contact and left foot contact was deviated from a figure of rectangle, whereas in case of normal person the ground reaction force was revealed in the figure of rectangle. 3. In case of amputee group, the ground reaction force referred to both feet angle point of view was revealed in irregular figure, whereas in case of normal person the ground reaction force was revealed about 47。

육상 양식장 인접해역의 해양학적 환경특성

조규대,이충일,김동선,양윤정 한국환경과학회 2002 한국환경과학회지 Vol.11 No.4

Field observations for research of oceanographic characteristics in waters adjacent to fish farm on land and water quality at area where water is supplied to fish farm and area where water is discharged from fish farm are carried out in coastal waters of Pyoson located in the southeastern region of Jeju Island in March, May, August and November of 2000. Semidiurnal tides to the northeast and southwest dominate. The mean velocities of current around neap tides and spring tides are 8.52㎝·s^-1, 28.36㎝·s^-1, respectively. The difference of temperature between area where water is supplied to fish farm and area where water is discharged from fish farm is about 0.6℃. Seasonal variation range for temperature and salinity is 13.5℃ and 3.5psu, individually. Concentrations of nitrate(NO_3), phosphate(PO_4^3-), silicate(SiO_2) and COD(chemical oxygen demand) are high in autumn. Particularly, concentrations of nitrate and COD in winter and spring at station where water is supplied to fish farm are higher than these at station where water is dischared from fish farm. However, concentration of phosphate and silicate at station where is supplied to fish farm in spring, summer and autumn is higher than that at station where water is dischared from fish farm. Water quality in the study area is grade 1 and this level is kept up in the whole year.

대학생의 단극성 우울증 치료를 위한 프로그램의 개발

전윤식,정영홍,안창규,임종찬,김정자 釜山大學校 學生生活硏究所 1986 硏究報 Vol.22 No.1

The study was to develop a Korean college student version of the Psychoeducational Intervention Program for unipolar depression originally developed by Lewinsohn et. al. (1982). In addition, the study was to find the effectiveness and any procedural problems for the application to the college students in unipolar depression. In order to achieve the above purposes, seven college students among volunteers were selected in terms of Beck Depression Inventory (BDI) and Depression scale of MMPI(MMPI-D). All the subjects scored above 70 points of T-score on MMPI-Depression scale, below 60 points of t-score on MMPI-Mania scale, and also above 16 points on BDI. The original program by Lewinsohn et. al. (1982) was translated and revised to seven session program for college students and also reconstructed the related materials which were workbooks and activity tasks. Examining the effectiveness of the program to the college students, pre- and post- tests of BDI and MMPI-D were given. The results showed that there were significant reduction of post- test scores of BDI and MMPI-D. Therefore, the program was confirmed to be effective for the college students in unipolar depression. The main procedural problems implementing the program was how to make students in depression actively follow and motivate in the procedures of the program.

교정적 치아초기배열단계시 발생하는 치근 변화에 관한 주사전자현미경적 연구 : A SCANNING ELECTIRON MICROSCOPIC STUDY

최정윤,정규림 대한치과교정학회 1998 대한치과교정학회지 Vol.28 No.4

본 연구는 교정치료를 목적으로 발치가 예정된 치아를 대상으로 임상적으로 매우 중요한 치료과정 중의 한 부분인 초기치아배열단계에서 다양한 기간과 크기의 교정력을 가하여 치아배열기간, 교정력의 크기, 치아이동방향에 따라 치근표면에 일어나는 흡수와 회복 양상에 대한 정보를 얻기 위하여 시행되었다. 치료받지 않은 13개의 치아를 대조군으로 하고 교정치료계획상 제1소구치를 발거하기로 예정된 37개의 치아를 실험군으로 하여 20-450gm의 초기교정력을 가한 후 주사전자현미경적 관찰을 통하여 다음과 같은 결과를 얻었다. 1. 실험군 37개 중 22개의 치아(59.5%)에서 치근흡수가 발견되었다. 치근흡수는 최소실험기간인 3주군부터 나타났으며 흡수부위의 회복은 3개월군부터 나타났다. 2. 교정력의 기간 증가에 따라 치근흡수의 발생빈도가 증가하는 경향을 보였다. 3. 교정력이 클수록 상아질을 포함하는 흡수가 증가하는 경향을 보였다. 4. 치근 흡수의 부위는 하중 받는 부위와 일치하는 경향을 보였다. 5. 치근 흡수 부위는 면적과 가장 상관성이 높은 변수는 교정력의 크기였다. The purpose of this study was to investigate the root resorption and repair pattern of human teeth according to the force magnitude, direction and duration during the initial leveling and alignment phase. 40gms to 500gms of force applied to the 37 experimental teeth with duration of 3 weeks to 7 months. Then, the experimental teeth were extracted. 13 control teeth were extracted without treatment. The results are as follows: 1. 59.5% of 37 teeth exhibited root resorption. The initial resorption site was visible at the apex within 3 weeks with 100 gms samples, and the initial repair site was visible at the apex within 3 months with 400 gms samples. 2. Number of resorbed teeth increased with the duration of the force. 3. The depth of the resorption increased with the magnitude of the force. 4. The areas of resorbed root corresponded with the loading pattern. 5. The areas of resorbed root were highly correlated with the magnitude of the force. The result of this study suggest that root resorption could occur during the initial leveling and alignment phase. These initial injuries are all small and insignificant. It is the extensive type of apical root resorption that must be regarded as deleterious to the function and stability of the tooth moved. During the initial leveling and alignment phase lighter force of the interrupted type and short treatment period would be favorable with regard to avoidance of root resorption and repair of resorbed root surface.

복직근 및 박근 근피판술을 이용한 골반 및 서혜부 연부조직 결손의 재건

이재화,정윤규,김주봉,유대현,황성관,이훈범,김석원 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.6

Many operations for the reconstruction of the pelvic area have been studied until now. The local muscle flap is often used for the closure of these complex wound. But, these local muscle flaps may not be available for reconstruction due to the factors of infection, radiation, and surgical trauma. Since rectus abdominis muscle and gracilis muscle were introduced, their use has been steadily increased for the reconstruction of soft tissue defect of the pelvic area. Inferiorly based rectus abdominis muscle flap and the gracilis muscle flap have been adopted for well-vascularized soft tissue coverage of the defect of pelvis and groin area. These techniques were utilized in seven patients. Of these patients, rectus abdominis muscle flap was used on four patients and three patients were treated with gracilis muscle flap. Among these, chronic osteomyelitis of pelvic bone has been managed with inferiorly based rectus abdominis muscle flap in three patients. No complication has been found. The mean postoperative follow-up period was 26 months, with a range of 12 to 39 months. In conclusion, these muscles are functionally expandable , and provide adequate tissue volume with sufficient blood supply away from the zone of injury, and readily transposed into the pelvis and groin area through subcutaneous tunnel, and serve as an antibiotic delivery system that aids in the eradication of infection. These findings suggest a reconstructive option for the defect of pelvis and groin, and/or bone infection in this area.

유리피판을 이용한 하인두-식도 재건 치험례

봉정표,정윤규,이훈범,김주봉,이재화,나동균,김석원 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.6

Hypopharyngo-esophageal cancer is usually found at late stage. Its main treatment is surgical intervention and it often requires radical resection. Reconstruction of the hypopharyngo-esophageal defect after the resection of carcinomas of the hypopharynx and the cervical esophagus has traditionally been carried out with deltopectoral or musculocutaneous flap. Another approach is to reconstruct the defect with the colon or stomach. Recent advances in microvascular surgical techniques have resulted in one stage reconstruction with free flap. Both jejunal free flap and radial forearm free flap is a good alternative for the reconstruction of hypopharyngo-esophageal defect. Six cases of the radial forearm flap and nine cases of the jejunal flap were used to reconstructed the hypopharyngo-esophageal defect in 15 patients. In jejunal free flap, upper margin was reconstructed with end to side anastomosis and lower margin with end to end anastomosis. In radial forearm free flap, we used trapezoid shaped flap and tubed by complete or partial tubing according to the condition of the defects. Stricture and fistula are troublesome complications. The complications were peritonitis(n=1) and fistula(n=1). We concluded that both forearm and jejunal free flap is a useful alternative in reconstruction of hypopharynx and cervical esophagus.