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      • KCI등재

        龍潭遺詞에 나타난 水雲像

        尹錫山,金容德 한양대학교 한국학연구소 1986 韓國學論集 Vol.10 No.-

        The purpose of this study is to ponder on Su-Un's image in Yong Dam- You-Sa. Because Yong-Dam-You-Sa is the kind of literary work, Ka-sa (歌辭), the persona in it isn't considered Su-Un himself, its author. But no one also deny its persona can be considered Su-Un because of the li- terary speciality of Ka-sa. This study, therefore, divides Su-Un's life into several parts firstly and analyzes some sections of Yong-Dam-You-Sa applied to each of them afterwards and makes clear his image ultimately. His life can be devided by the two phrases roughly. The first is the aspect before the spiritual awakening and the second the one after that. He looked into the customs through going around the country before the spiritual awakening and sought after truth in order to deliver the troublous world. He attained the awakrning in April, 1860 and then began to work for the enlightment of the public. Su-Un inspired the public with such modern thought of equality as Si-Chun-Ju (侍天主; the thought that each one of all mankind has the god in himself) and inspired them with elitism. Consequently, those thoughts raised their hopes so much and became the spiritual essence to overcome the national crisis. According to those aspects, Su-Un is considered a modern master rather than a hero of the puble.

      • 기본 항암 화학요법에 불응 하는 전이성 이행상피 세포암 환자에서 시행한 증량 M-VAC 항암 화학 요법 2례

        조용현,권병산,이지열,김세웅,이충범,윤문수 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.3

        1. 목적 전이성 방광 이행 상피 세포암의 경우에 시행될 수 있는 몇가지 전신적 항암 요법 중 M-VAC 병용 투여가 가장 인정받고 있는 항암 요법이긴 하나 일시적 반응 후 재발시 즉 M-VAC 병용투여에 불응하는 경우 증상 완화 요법(palliative therapy) 이외에 다른 치료 방법이 없었다. 저자들은 M-VAC 병용 요법에 불응하는 전이성 방광 이행상피 세포암 환자 2례에서 기존 M-VAC 항암 화학 요법보다 항암제 투여량을 증량한 M-VAC 항암 요법을 시행하였다. 2. 방법 기존 M-VAC 항암 화학요법용량(Methotrexate 30㎎/㎡, Vinblastine 3㎎/㎡, Adriamysin 30㎎/㎡, Cisplatin 70㎎/㎡)보다 항암제 용량을 증량하고(Methotrexate 30㎎/㎡, Vinblastine 4㎎/㎡, Adriamycin 60㎎/㎡, Cisplatin 100㎎/㎡) 이로 인한 골수 저하증을 예방하기 위하여 GM-CSF를 동시에 투여하였다. 3. 결과 증례 1 환자는 중량 항암 화학 요법 1개월 후 추적검사에서 전이된 임파절이 모두 소실된 완전 관해를 보였으며 증례 2 환자는 증량 항암 요법 후 14일째 폐혈증으로 사망하였다. 4. 결론 증량 M-VAC 항암 화학 요법은 아직 시행 기간 및 증례가 많지 않아 완전 관해 기간 및 적절한 항암요법 시행 횟수의 미확립, 항암제 치료 도중의 치사율의 감소등이 문제점으로 지적되고 있으나 기존 M-VAC 항암 요법에 불응하는 전이성 방광이행 상피 세포암 환자에서 우선 고려될 수 있는 치료법으로 사료된다. Background : M-VAC(methotrexate, vinblastine. doxorclbicin, cisplatin) chemotherapy is the most common and effective treatment modality for advanced transitional bladder tumor. However, there is no effective therapy in case of the patients nith bladder tumor refractory to M-VAC chemotherapy. Methods : Two male patients mith metastatic transitional bladder tumors refractory to conventional chemotherapy with methbtrexate, vinblastine, doxorubicim, and cispiatin (M-VAC) were treated with escalate3 dose of M-VAC plus recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF). Formula of escalated M-VAC chemotherapy were 30mg/m^(2) of inethotrexate, 4mg/m^(2) of vinblastine. 60rmg/m^(2) of doxorubicm, and 10Omg/m^(2) of cisplatin, and 250mg/m^(2) rhGM-CSF per day administered subcutaneously (SC) for 10 consecutive days. Result : One of the treated patients mas responded with complete remission and the other one m-as dead by sepsis on post-escalated M-VAC chenctherapy 14 days. Coclusion : We believe escalated M-VAC chemotherapy may be one of the effective alternative treatment for patients with metastatic urothelial tumor refractory to conventional M-VAC chemotherapy.

      • KCI등재

        한국 재래 산양에서 Leptospira spp.에 대한 혈청역학적 연구

        한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

        Between January 1999 and September 2001, 948 sera (120 from each province except 108 from Chungbuk) from 8 provinces were sampled from Korean goats. All the samples were serologically tested for Leptospira spp. By the microscopic agglutination test against four L. interrogans serovars including canicola, icterohaemorrhagiae, pomona and hardjo, 948 Korean goats were confirmed as 11 seropositives (1.2%) only infected with L. icterohemorrhagiae. All positive sera were collected from Gyeonggi (5), Gangwon (4) and Chungbuk (2). Titration of them were classified as 1:100 of 10 sera except one case with 1:200 from Gyeonggi. It was meaningful that the pathogen in Korean goats was mainly distributed in the northen part of the country. Consequently, the results in the study were confirmed and analyzed the recent status of infection of leptospirosisas zoonotic agentsome in Korean goats.

      • KCI등재

        한국 재래산양에서 Bovine Viral Diarrhea, Bovine Herpesvirus-1, Parainfluenza Type-3 바이러스에 대한 혈청학적 연구

        한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

        The 948 goat sera were serologically tested for ten pathogens including bovine viral diarrhea (BVD), bovine herpes virus type-1 (BHV-1) and parainfluenza virus type-3 (PI-3). By viral neutralizaion test, three pathogens including BVD virus, BHV-1, PI-3 were applied for screening each neutralizing antibody and its titration. Among 948 sera, there were 215 seropositives (22.7%) against BVD virus, 25 (2.6%) against BHV-1 virus, and 161 (17.0%) against PI-3 virus, respectively. In the seropositive cases to BVD virus, provincial prevalence of them were recorded as Gyeongnam(30.8%) for the highest one, while as Jeonbuk (15.8%) and Gyeongbuk(l6.7%) relatively for the lower ones. Among them, higher than 1:8 in antibody titration was classified as 74 cases (34.4%) which were suspected the cycle of its infection in their herds. Among the seropositives to BHV-1, it was relatively lower prevalence rate ranging from 1.7% to 6.7% that those of BVD virus and PI-3, but more importantly they were prevailing across the country. Most of the seropositive cases (42.9%) to PI-3 were classified as 1:4-1:16 in titration, but also distributed all around the country. The prevalence in goats varied according to areas (15.8 to 30.8%). Related to the provincial prevalence of three viral agents in Korean goats, it seemed that three viral pathogens would be directly or indirectly involving in various disorders as primary or secondary causative agents resulting in decreased productivity.

      • SCIESCOPUSKCI등재
      • Enumeration of axial rotation

        Yoon, Yong-San Techno-Press 2014 Advances in biomechanics & applications Vol.1 No.2

        In this paper, two procedures of enumerating the axial rotation are proposed using the unit sphere of the spherical rotation coordinate system specifying 3D rotation. If the trajectory of the movement is known, the integration of the axial component of the angular velocity plus the geometric effect equal to the enclosed area subtended by the geodesic path on the surface of the unit sphere. If the postures of the initial and final positions are known, the axial rotation is determined by the angular difference from the parallel transport along the geodesic path. The path dependency of the axial rotation of the three dimensional rigid body motion is due to the geometric effect corresponding to the closed loop discontinuity. Firstly, the closed loop discontinuity is examined for the infinitesimal region. The general closed loop discontinuity can be evaluated by the summation of those discontinuities of the infinitesimal regions forming the whole loop. This general loop discontinuity is equal to the surface area enclosed by the closed loop on the surface of the unit sphere. Using this quantification of the closed loop discontinuity of the axial rotation, the geometric effect is determined in enumerating the axial rotation. As an example, the axial rotation of the arm by the Codman's movement is evaluated, which other methods of enumerating the axial rotations failed.

      • SCOPUSKCI등재

        Application of two different synthetic sequential media for the human IVF-ET program: a prospective, randomized, and comparative study

        Yoon, Jeong,Yoon, Hye-Jin,Juhn, Kyoung-Mi,Ko, Jin-Kyung,Yoon, San-Hyun,Ko, Yong,Lim, Jin-Ho The Korean Society for Reproductive Medicine 2011 Clinical and Experimental Reproductive Medicine Vol.38 No.4

        Objective: Since IVF program was first established, various types of media and culture systems have been developed either in-house or commercially. The aim of this study was to compare the efficacy of in-house Maria Research Center (MRC) media to that of commercially available Sydney IVF media in human day 3 embryo transfer cycles. Methods: Three hundred sixty nine couples were included in this prospective, randomized, and comparative study. All couples undergoing IVF treatment at the Maria Fertility Hospital were randomly assigned to either Sydney IVF (n=178) or MRC (n=191) media. Results: No difference was observed between the MRC media and Sydney IVF media groups with respect to fertilization rate (74.4% vs. 75.5%). The clinical pregnancy and implantation rates of MRC media (47.1% and 20.0%, respectively) were also similar to those of Sydney IVF media (44.4% and 19.4%, respectively). However, the proportion of embryos with good quality on day 3 was significantly higher in the MRC media group than the Sydney IVF media group (50.2% vs. 43.2%) ($p$ <0.05). Conclusion: MRC media were as effective as Sydney IVF media for sustaining embryo development and pregnancy rates. The present study implies that MRC media can be a suitable alternative to commercially available media for human IVF-ET program.

      • SCOPUSKCI등재

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