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복와위 상태 중환자에서의 영양공급에 따른 임상적 예후 분석
이연주 ( Yeonju Lee ),김형숙 ( Hyung-sook Kim ),남궁형욱 ( Hyungwook Namgung ),이은숙 ( Eun Sook Lee ),김은경 ( Euni Lee ),조영재 ( Young-jae Cho ),이연주 ( Yeon Joo Lee ) 한국정맥경장영양학회 2018 한국정맥경장영양학회지 Vol.10 No.1
Purpose: Enteral nutrition is recommended in critically ill patients. On the other hand, the recommendation of nutritional support is limited and often controversial in critically ill patients in the prone position. Therefore, this study evaluated the clinical outcomes of nutritional support in critically ill patients in the prone position. Methods: A retrospective evaluation of the electronic medical records was conducted, including adult patients who were in the medical intensive care unit (ICU) in the prone position in Seoul National University Bundang Hospital from May 1, 2015 to June 30, 2017. The patients’ characteristics, nutritional support status while they were in the prone position, mortality in ICU and during hospitalization, ICU length of stay, mechanical ventilation days, and complications, such as ventilator associated pneumonia (VAP) and vomiting were collected. Results: In total, 100 patients were included. Of these, 12 received enteral nutrition and parenteral nutrition and 88 received only parenteral nutrition. The groups were similar in terms of age, sex, number of comorbidity, weight, PaO<sub>2</sub>/FiO<sub>2</sub>, hours of prone position, Simplified Acute Physiology Score II (SAPS II), Acute Physiologic and Chronic Health Evaluation II (APACHE II) score, and Sequential Organ Failure Assessment (SOFA) score. No differences were observed in ICU mortality (75.0% vs. 46.6%; P=0.065), hospital mortality (83.3% vs. 58.0%; P=0.081), ICU length of stay (22.2±14.6 vs. 18.2±21.2; P=0.128) and mechanical ventilation days (19.3±14.8 vs. 14.5±19.1; P=0.098). In addition, there were no differences in the possible complications of the prone position, such as VAP (8.3% vs. 4.5%; P=0.480) and vomiting (8.3% vs. 1.1%; P=0.227). Conclusion: No significant differences in the clinical outcomes were observed. Further studies will be needed to confirm the way of nutrition support while in the prone position.
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동화활용 언어프로그램이 유아의 창의성 향상에 미치는 효과
이경화(Lee Kyunghwa),이연주(Lee Yeonju) 한국영재교육학회 2008 영재와 영재교육 Vol.7 No.1
본 연구는 동화를 이용한 언어활동 프로그램이 유아의 창의성 향상에 미치는 효과를 확인함으로써, 유아의 창의성 향상을 위한 효과적인 교수프로그램 개발을 위한 자료로 제공하고자 하는데 목적이 있다. 따라서 본 연구에서는 동화활용 언어프로그램이 유아의 언어와 도형 영역에서의 창의성 향상에 효과적일 것이라는 가설을 설정하고 이를 검정하였다. 본 연구의 대상은 유아 12명으로, 이들을 무선 선발하여 실험집단과 통제집단에 각 6명씩 무선 배치한 후 사전검사를 실시하여 동질성을 확인하였다. 수업은 주 2회씩 총 12회에 걸쳐 실험을 실시하였다. 연구 결과, 동화활용 언어프로그램이 유아의 언어와 도형영역에서의 창의적 능력과 창의적 성격 향상에 효과적임이 확인되었다. 따라서 유아의 창의성을 계발시키고자 하는 수업에 본 연구에서 개발된 것과 같은 동화활용 언어프로그램을 적용한다면 유아교육현장에서 효과적으로 사용할 수 있을 것이다. The objective of this study is to certify what effects language activity programs have on progress in children"s creativity. That is, this study aims at finding an effective teaching method for progress in creativity by clarifying whether telling fairy tales to children and making them participate in language activities have effects on the development of a rich imagination, curiosity, and creative ideas, and on the formation of creative personality.<BR> The hypothesis of this study was that language activity programs using fairy tales would affect progress in children"s linguistic and creative abilities in a figural field and their creative personality.<BR> A total of twelve 5-year-old children were randomly sampled and the respective six subjects were then classified into an experimental group which applied language activity programs using fairy tales and a control group where teachers mainly led language activities. These experiments were conducted twice every week for 6 weeks from March 23rd to April 27th, 2007, amounting to 12 sessions.<BR> As instruments, "Integrated Creativity Test for Children" developed by Lee Kyung-hwa and Lee Shin-dong(2003) was used for both pre-and post- test. Then data was treated by SPSS WIN 12.0 to conduct the t-test.<BR> The results of this study were summarized as the following:<BR> First, children in the experimental group who participated in language activity programs using fairy tales increased their creative ability(linguistic creativity and figural creativity) more than the control group where the teacher led general language activities.<BR> Second, children in the experimental group who participated in language activity programs using fairy tales showed progress in their linguistic creativity (imagination, fluency, and originality) more than the control group. That is, the language activity programs using fairy tales had positive effects on progress in linguistic creativity.<BR> Third, children in the experimental group who participated in language activity programs using fairy tales showed progress in their figural creativity(continuity, connection, accomplishment, addition of new elements, themes, and nonhabituation) more than the control group. In other words, language activity programs using fairy tales had positive effects on progress in children"s figural creativity.<BR> Fourth, children in the experimental group who participated in language activity programs using fairy tales improved their creative personality(curiosity, independence, adventurous spirit, and attachment to assignments) more than the control group. That is, the language activities programs using fairy tales had positive effects on progress in children"s creative personality.<BR> In conclusion, it was verified that the language activity programs using fairy tales had positive effects on the progress of the children"s creativity. Therefore, the program is expected to be used as a teaching method for a progress in children"s creativity in the field of early childhood education.
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PNF 상지패턴에 기초한 진동운동기구 훈련이 노인의 체간 안정성과 균형에 미치는 영향
이형수 ( Hyoungsoo Lee ),임정대 ( Jungdae Im ),이기훈 ( Gihun Lee ),이지성 ( Jiseong Lee ),이진욱 ( Jinwuk Lee ),손지윤 ( Yeonju Seo ),서연주 ( Jiyoon Son ),안효정 ( Hyojoeng An ),오현정 ( Hyunjeong Oh ),윤하늘 ( Haneul Youn ),이서연 대한통합의학회 2015 대한통합의학회지 Vol.3 No.3
Purpose : This study examines the effect of vibration exercise grafting PNF patterns for 6 weeks on upper body stability and equilibrium for seniors having fifteen or over of MMSE-K. Method : A total of 10 senior citizens participated in this study. Each participant performed PNF patterned exercises using vibration sports equipment for 30 minutes, once static a week, for six weeks. We measured trunk stability and balance degree before and after the six-week exercise program. Motor Assessment Scale (MAS) was used to measure trunk stability, while Functional Reach Test (FRT) and Timed Up and Go (TUG) was used to measure balance degree. The collected data was processed using paired t-test to confirm the difference between pre-program conditions and post-program conditions. Results: The results of our study show that post-program trunk stability measurements increased when compared to pre-program data; however, this increase was not statistically significant. pre and post-measurements for satatic balance and dynamic balance were statistically unchanged. Conclusion: Due to limitations in the number of participants, the procedural design of this experiment, and the limited amount of time participants actually controlled, this study failed to produce statistically significant results. However, further study should be conducted using a systematically implemented exercise program to show support for exercising with flexi-bar as an effective program for the elderly.
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Chemical Characteristics for the CeO2 Samples Containing Mo Epsilon Particle
Yeonju Lee,Youngsang Youn 한국방사성폐기물학회 2022 한국방사성폐기물학회 학술논문요약집 Vol.20 No.1
To evaluate the chemical properties of the epsilon particle present as a precipitate in the high-level radioactive waste, we performed the experiments for the samples fabricated by CeO2 containing 1, 3, and 5wt%Mo, where CeO2 is used as the simulated high-level radioactive waste to replace the real one, using X-ray diffraction (XRD), X-ray absorption spectroscopy (XAS), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy-energy dispersive X-ray spectroscopy (SEMEDS). Moreover, to evaluate the chemical behavior of Mo epsilon particle in CeO2 at high temperature, the manufactured CeO2-1wt%Mo, CeO2-3wt%Mo, and CeO2-5wt%Mo samples were heated at 100, 300, 500, 700 and 900ºC for 7 h in a tube furnace under Ar atmosphere. In this study, the results of comprehensive analysis including the crystal structure, chemical state, and elemental distribution will be presented to verify the chemical properties for CeO2 samples containing Mo epsilon particle, depending on the Mo content and heating temperature.
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Lee, Yeonju,Jung, Jae-Chul,Ali, Zulfiqar,Khan, Ikhlas A.,Oh, Seikwan Hindawi Publishing Corporation 2012 Evidence-based Complementary and Alternative Medic Vol.2012 No.-
<P>Blue cohosh has been used as a medicinal herb in eastern North America. It was commonly used as traditional medicines for the treatment of menopausal symptoms, rheumatic pain, and as anti-inflammatory remedy. Particularly, extract of blue cohosh roots has been used as anti-inflammatory antipyretic in traditional medicines. In the present study, we investigated the effects of blue cohosh components on the suppressive expression of iNOS or proinflammatory cytokines after the activation of microglia with lipopolysaccharide (LPS). The expression of iNOS, TNF-<I><I>α</I></I>, IL-1<I><I>β</I></I>, and IL-6 was determined by western blotting or gene expression. Blue cohosh treatment suppressed the elevation of LPS-induced iNOS expression in a concentration-dependent manner in microglia cells. Blue cohosh constituents also suppressed the expression of TNF-<I><I>α</I></I>, IL-1<I><I>β</I></I>, and IL-6. In addition, blue cohosh extract suppressed the expression of COX-2, iNOS, and proinflammatory cytokines in adrenal glands of mice. These results demonstrate that constituents of blue cohosh exert anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines. Therefore, blue cohosh may have therapeutic potential for the treatment of inflammation-related diseases.</P>
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Administration of red ginseng ameliorates memory decline in aged mice
Lee, Yeonju,Oh, Seikwan The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.3
Background: It has been known that ginseng can be applied as a potential nutraceutical for memory impairment; however, experiments with animals of old age are few. Methods: To determine the memory enhancing effect of red ginseng, C57BL/6 mice (21 mo old) were given experimental diet pellets containing 0.12% red ginseng extract (approximately 200 mg/kg/d) for 3 mo. Young and old mice (4 mo and 21 mo old, respectively) were used as the control group. The effect of red ginseng, which ameliorated memory impairment in aged mice, was quantified using Y-maze test, novel objective test, and Morris water maze. Red ginseng ameliorated age-related declines in learning and memory in older mice. In addition, red ginseng's effect on the induction of inducible nitric oxide synthase and proinflammatory cytokines was investigated in the hippocampus of aged mice. Results: Red ginseng treatment suppressed the production of age-processed inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-${\alpha}$, and interleukin-$1{\beta}$ expressions. Moreover, it was observed that red ginseng had an antioxidative effect on aged mice. The suppressed glutathione level in aged mice was restored with red ginseng treatment. The antioxidative-related enzymes Nrf2 and HO-1 were increased with red ginseng treatment. Conclusion: The results revealed that when red ginseng is administered over long periods, age-related decline of learning and memory is ameliorated through anti-inflammatory activity.
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Administration of red ginseng ameliorates memory decline in aged mice
Yeonju Lee,오세관 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.3
Background: It has been known that ginseng can be applied as a potential nutraceutical for memory impairment; however, experiments with animals of old age are few. Methods: To determine the memory enhancing effect of red ginseng, C57BL/6 mice (21 mo old) were given experimental diet pellets containing 0.12% red ginseng extract (approximately 200 mg/kg/d) for 3 mo. Young and old mice (4 mo and 21 mo old, respectively) were used as the control group. The effect of red ginseng, which ameliorated memory impairment in aged mice, was quantified using Y-maze test, novel objective test, and Morris water maze. Red ginseng ameliorated age-related declines in learning and memory in older mice. In addition, red ginseng’s effect on the induction of inducible nitric oxide synthase and proinflammatory cytokines was investigated in the hippocampus of aged mice. Results: Red ginseng treatment suppressed the production of age-processed inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-a, and interleukin-1b expressions. Moreover, it was observed that red ginseng had an antioxidative effect on aged mice. The suppressed glutathione level in aged mice was restored with red ginseng treatment. The antioxidative-related enzymes Nrf2 and HO-1 were increased with red ginseng treatment. Conclusion: The results revealed that when red ginseng is administered over long periods, age-related decline of learning and memory is ameliorated through anti-inflammatory activity.
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