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Yebin D. Ahn,Dahyun Yi,Haejung Joung,Eun Hyun Seo,Young Hwa Lee,Min Soo Byun,이준호,So Yeon Jeon,Jun-Young Lee,Bo Kyung Sohn,Dong Young Lee,KBASE Research Group 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.11
Objective The purpose of this study is to identify the demographic variables that are affecting performances on the Logical Memory (LM) subtest included in the Korean version of the Wechsler Memory Scale (WMS)-IV and to provide normative data on the LM subtest for the middle-age and elderly Korean people. Methods The participants were 435 non-demented adults aging from 50 to 90 and with the educational level ranging from 0 to 21 years. Results Age and education were found to be significantly associated with performance on the LM subtest, while gender effect was not statistically significant. Therefore, we stratified the norm blocks by age and education. Age was divided into three groups: 50–59, 60–74, and 75–90 years. Education was stratified into three groups: 0–8 years, 9–12 years, and 13 years or more. Conclusion The normative data provided in the current study are expected to be useful in clinical and research settings to detect or define subtle changes in episodic memory in Korean adults and elderly, and can also be used for cross-cultural comparison of verbal episodic memory performance among elderly populations using different languages.
Psychological Aspects of Child Maltreatment
Ahn, Yebin D.,Jang, Soomin,Shin, Jiyoon,Kim, Jae-Won The Korean Neurosurgical Society 2022 Journal of Korean neurosurgical society Vol.65 No.3
In this review, we provide information about the etiology, risk factors, and clinical presentations of maltreatment to help clinicians better understand child abuse and neglect. Child maltreatment is a major global health challenge that can result in severe consequences. Abused and neglected children are likely to develop psychiatric disorders, such as major depressive disorder, anxiety disorder, and posttraumatic stress disorder. Understanding child maltreatment is expected to prevent and reduce victimization in children, adolescents, and their families.
( Yebin Ahn ),( Jongchul Lee ),( Hanseok Kwon ),( Jungbin Hong ),( Han-don Um ) 한국전기전자재료학회 2024 전기전자재료학회논문지 Vol.37 No.2
This paper introduces an optimized oxygen (O<sub>2</sub>) plasma surface treatment technique to enhance sphere lithography on hydrophobic photoresist surfaces. The focus is on semiconductor manufacturing, particularly the creation of finer structures beyond the capabilities of traditional photolithography. The key breakthrough is a method that makes substrate surfaces hydrophilic without altering photoresist patterns. This is achieved by meticulously controlling the O<sub>2</sub> plasma treatment duration. The result is the consistent formation of nano and microscale patterns across large areas. From an academic perspective, the study deepens our understanding of surface treatments in pattern formation. Industrially, it heralds significant progress in semiconductor and precision manufacturing sectors, promising enhanced capabilities and efficiency.
Psychiatric Manifestation in Patients with Parkinson's Disease
한지원,Yebin D. Ahn,김원석,신철민,정성진,송유성,배윤정,김종민 대한의학회 2018 Journal of Korean medical science Vol.33 No.47
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life — and the need for institutionalization — is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.
Jung, Yebin,Jeong, Sanghwa,Nayoun, Won,Ahn, Boeun,Kwag, Jungheon,Geol Kim, Sang,Kim, Sungjee SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS 2015 JOURNAL OF BIOMEDICAL OPTICS Vol.20 No.4
<P>Quantum dot (QD) imaging capability was investigated by the imaging depth at a near-infrared second optical window (SOW; 1000 to 1400 nm) using time-modulated pulsed laser excitations to control the effective fluence rate. Various media, such as liquid phantoms, tissues, and in vivo small animals, were used and the imaging depths were compared with our predicted values. The QD imaging depth under excitation of continuous 20 mW/cm(2) laser was determined to be 10.3 mm for 2 wt%hemoglobin phantom medium and 5.85 mm for 1 wt% intralipid phantom, which were extended by more than two times on increasing the effective fluence rate to 2000 mW/cm(2). Bovine liver and porcine skin tissues also showed similar enhancement in the contrast-to-noise ratio (CNR) values. A QD sample was inserted into the abdomen of a mouse.With a higher effective fluence rate, the CNR increased more than twofold and the QD sample became clearly visualized, which was completely undetectable under continuous excitation.Multiple acquisitions of QD images and averaging process pixel by pixel were performed to overcome the thermal noise issue of the detector in SOW, which yielded significant enhancement in the imaging capability, showing up to a 1.5 times increase in the CNR.</P>
Multiplexed In Vivo Imaging Using Size-Controlled Quantum Dots in the Second Near-Infrared Window
Jeong, Sanghwa,Jung, Yebin,Bok, Seoyeon,Ryu, Yeon-Mi,Lee, Sumin,Kim, Young-Eun,Song, Jaejung,Kim, Miyeon,Kim, Sang-Yeob,Ahn, G-One,Kim, Sungjee Wiley (John WileySons) 2018 Advanced Healthcare Materials Vol.7 No.24
Alterations in Social Brain Network Topology at Rest in Children With Autism Spectrum Disorder
Narae Yoon,Youngmin Huh,Hyekyoung Lee,Johanna Inhyang Kim,Jung Lee,Chan-Mo Yang,Soomin Jang,Yebin D. Ahn,Mee Rim Oh,Dong Soo Lee,Hyejin Kang,Bung-Nyun Kim 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.12
Objective Underconnectivity in the resting brain is not consistent in autism spectrum disorder (ASD). However, it is known that the functional connectivity of the default mode network is mainly decreased in childhood ASD. This study investigated the brain network topology as the changes in the connection strength and network efficiency in childhood ASD, including the early developmental stages. Methods In this study, 31 ASD children aged 2–11 years were compared with 31 age and sex-matched children showing typical development. We explored the functional connectivity based on graph filtration by assessing the single linkage distance and global and nodal efficiencies using resting-state functional magnetic resonance imaging. The relationship between functional connectivity and clinical scores was also analyzed. Results Underconnectivities within the posterior default mode network subregions and between the inferior parietal lobule and inferior frontal/superior temporal regions were observed in the ASD group. These areas significantly correlated with the clinical phenotypes. The global, local, and nodal network efficiencies were lower in children with ASD than in those with typical development. In the preschool-age children (2–6 years) with ASD, the anterior-posterior connectivity of the default mode network and cerebellar connectivity were reduced. Conclusion The observed topological reorganization, underconnectivity, and disrupted efficiency in the default mode network subregions and social function-related regions could be significant biomarkers of childhood ASD.
Min-Sup Shin,Bung-Nyun Kim,Minji Cho,Mirae Jang,Hanbyul Shin,Ryemi Do,Hyungseo Park,Narae Yoon,Gahye Noh,Jae-Won Song,Yebin Ahn,Jiyoon Shin,Soomin Jang,Eunjung Noh,Eunhwa Lee 대한소아청소년정신의학회 2021 소아청소년정신의학 Vol.32 No.2
Objectives: This study was conducted to investigate the reliability and validity of the Korean version of the DSM-5 Level 2 Cross-Cutting Symptom Measure–inattention [Swanson, Nolan and Pelham, version IV (SNAP-IV)] and anger [Patient-Reported Outcome Measurement Information System (PROMIS) Anger] for parents and guardians of children aged 6–17 years. Methods: We included 104 children and adolescents diagnosed with attention-deficit/hyperactivity disorder (ADHD), ADHD with anxiety and depression, depressive disorder, anxiety disorder, and tic disorder with somatic symptoms (ADHD=41, depression=9, anxiety=14, ADHD+anxious depression=11, tic+somatic symptoms=29). Their ages ranged from 8 years to 15 years. The participants’ mothers completed the SNAP-IV, PROMIS Anger scale, Korean version of the IOWA Conners Rating Scale (K-IOWA), and Korean ADHD Rating Scale (K-ARS) so that the reliability and validity of the SNAP-IV and PROMIS Anger scales, which are DSM-5 scales for assessing inattention and anger of children and adolescents, could be examined. Results: The reliability coefficient of SNAP-IV (Cronbach’s α) was 0.94. The correlation coefficients between SNAP-IV, K-IOWA inattention, and K-ARS inattention scores ranged from 0.73 to 0.86. The mean SNAP-IV scores of the ADHD and the ADHD+anxious depression groups were significantly higher than those of the anxiety and the tic+somatic symptoms groups. The reliability coefficient of the PROMIS Anger was 0.91. The correlation coefficient between PROMIS Anger and K-IOWA oppositional/defiant scores was 0.75. The PROMIS Anger mean score of the ADHD+anxious depression group tended to be higher than that of the other groups. Conclusion: These results suggest that the Korean version of the DSM-5 Level 2 Cross-Cutting Symptom Measure–inattention and anger for parent and guardian of child age 6–17 might be a reliable and valid test and may be useful for screening children and adolescents with ADHD.