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- 저자 : Xiang Haiyan (검색결과 6 건)
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Xiang Haiyan,Zhang Yun,Wu Yan,Xu Yaling,Hong Yuanhao 대한약리학회 2024 The Korean Journal of Physiology & Pharmacology Vol.28 No.1
Acute kidney injury (AKI) is one of the major complications of sepsis. Aurantio-obtusin (AO) is an anthraquinone compound with antioxidant and antiinflammatory activities. This study was developed to concentrate on the role and mechanism of AO in sepsis-induced AKI. Lipopolysaccharide (LPS)-stimulated human renal proximal tubular epithelial cells (HK-2) and BALB/c mice receiving cecal ligation and puncture (CLP) surgery were used to establish in vitro cell model and in vivo mouse model. HK-2 cell viability was measured using MTT assays. Histological alterations of mouse renal tissues were analyzed via hematoxylin and eosin staining. Renal function of mice was assessed by measuring the levels of serum creatinine (SCr) and blood urea nitrogen (BUN). The concentrations of pro-inflammatory cytokines in HK-2 cells and serum samples of mice were detected using corresponding ELISA kits. Protein levels of factors associated with nuclear factor kappa-B (NF-κB) pathway were measured in HK-2 cells and renal tissues by Western blotting. AO exerted nocytotoxic effect on HK-2 cells and AO dose-dependently rescued LPS-induced decrease in HK-2 cell viability. The concentrations of pro-inflammatory cytokines were increased in response to LPS or CLP treatment, and the alterations were reversed by AO treatment. For in vivo experiments, AO markedly ameliorated renal injury and reduced high levels of SCr and BUN in mice underwent CLP operation. In addition, AO administration inhibited the activation of NF-κB signaling pathway in vitro and in vivo. In conclusion, AO alleviates septic AKI by suppressing inflammatory responses through inhibiting the NF-κB pathway
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Ma Haiyan,Xie Chen,Zheng Shunlin,Li Peihua,Cheema Hafsa Nazir,Gong Jing,Xiang Zhuqing,Liu Juanjuan,Qin Jiahao 한국미생물학회 2022 The journal of microbiology Vol.60 No.2
Intensive potato continuous cropping (IPCC) results in low potato yields compared with non-intensive potato continuous cropping (PCC) and potato-maize rotation (PMRC). However, it is still unclear whether the degree of potato continuous cropping obstacle is related to the soil environment formed by the previous crop. To investigate the effect of planting potatoes and planting maize after harvesting the spring potatoes on soil chemical properties and soil microbial community structure, an experiment was carried out in the same origin soil environment over a period of seven years: (a) PCC, i.e., spring planting; (b) IPCC, i.e., autumn and spring planting (IPCC); (c) PMRC, i.e., spring potatoes and summer maize (PMRC), and (d) fallow (CK). We confirmed that the potato yield under PMRC was significantly higher than that under PCC and IPCC. Under IPCC, soil total phosphorus content was significantly higher than other treatments, whereas ammonium nitrogen content was the lowest. Compared with PCC and IPCC, PMRC had a higher ammonium nitrogen content and lower total phosphorus content. The significantly different fungal taxa in IPCC (Glomerellales, Plectosphaerella, Thelebolales) may threaten the health of the plant and positive correlated with soil total phosphorus, while other microbial taxa in PMRC (Bacillales, Polythrincium, Helotiales) can mainly promotes plant nitrogen uptake and protects plants against diseases. The PMRC-promoting taxa were positively correlated with the ammonium nitrogen content and negative correlated with soil total phosphorus content. In summary, the cropping systems might have affected potato yields by changed soil microorganism community structures – especially fungal community structures – and by the chemical properties of the soils that also depends on microbes.
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Current Status of Indoor Positioning System Based on Visible Light
Kun Yan,Haiyan Zhou,Hailin Xiao,Xiangli Zhang 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10
With the flourishing of wireless information access, indoor positioning is becoming a topic of interest in both academic and industry community. Numerous techniques have been proposed to address this problem under diverse circumstances. Recently, the area of indoor positioning is dominated by three kinds of methodologies, such as rangebased positioning, fingerprint-based positioning and inertial positioning. This paper is presented to overview the indoor positioning techniques using visible light based on the range-based positioning. The state-of-the-art research results will be studied. The typical localization mechanisms used in visible light positioning systems are analyzed by evaluation metrics to provide an insight of the systems’ performances.
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A hybrid simulated annealing and optimality criteria method for optimum design of RC buildings
Gang Li,Haiyan Lu,Xiang Liu 국제구조공학회 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.35 No.1
This paper proposes a hybrid heuristic and criteria-based method of optimum design which combines the advantages of both the iterated simulated annealing (SA) algorithm and the rigorously derived optimality criteria (OC) for structural optimum design of reinforced concrete (RC) buildings under multi-load cases based on the current Chinese design codes. The entire optimum design procedure is divided into two parts: strength optimum design and stiffness optimum design. A modified SA with the strategy of adaptive feasible region is proposed to perform the discrete optimization of RC frame structures under the strength constraints. The optimum stiffness design is conducted using OC method with the optimum results of strength optimum design as the lower bounds of member size. The proposed method is integrated into the commercial software packages for building structural design, SATWE, and for finite element analysis, ANSYS, for practical applications. Finally, two practical frame-shear-wall structures (15-story and 30-story) are optimized to illustrate the effectiveness and practicality of the proposed optimum design method.
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A hybrid simulated annealing and optimality criteria method for optimum design of RC buildings
Li, Gang,Lu, Haiyan,Liu, Xiang Techno-Press 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.35 No.1
This paper proposes a hybrid heuristic and criteria-based method of optimum design which combines the advantages of both the iterated simulated annealing (SA) algorithm and the rigorously derived optimality criteria (OC) for structural optimum design of reinforced concrete (RC) buildings under multi-load cases based on the current Chinese design codes. The entire optimum design procedure is divided into two parts: strength optimum design and stiffness optimum design. A modified SA with the strategy of adaptive feasible region is proposed to perform the discrete optimization of RC frame structures under the strength constraints. The optimum stiffness design is conducted using OC method with the optimum results of strength optimum design as the lower bounds of member size. The proposed method is integrated into the commercial software packages for building structural design, SATWE, and for finite element analysis, ANSYS, for practical applications. Finally, two practical frame-shear-wall structures (15-story and 30-story) are optimized to illustrate the effectiveness and practicality of the proposed optimum design method.
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