Modeling, Preparation, and Elemental Doping of Li₇La₃Zr₂O₁₂ Garnet-Type Solid Electrolytes: A Review

Cao, Shiyu,Song, Shangbin,Xiang, Xing,Hu, Qing,Zhang, Chi,Xia, Ziwen,Xu, Yinghui,Zha, Wenping,Li, Junyang,Gonzale, Paulina Mercedes,Han, Young-Hwan,Chen, Fei The Korean Ceramic Society 2019 한국세라믹학회지 Vol.56 No.2

Recently, all-solid-state batteries (ASSBs) have attracted increasing interest owing to their higher energy density and safety. As the core material of ASSBs, the characteristics of the solid electrolyte largely determine the performance of the battery. Thus far, a variety of inorganic solid electrolytes have been studied, including the NASICON-type, LISICON-type, perovskite-type, garnet-type, glassy solid electrolyte, and so on. The garnet Li₇La₃Zr₂O₁₂ (LLZO) solid electrolyte is one of the most promising candidates because of its excellent comprehensively electrochemical performance. Both, experiments and theoretical calculations, show that cubic LLZO has high room-temperature ionic conductivity and good chemical stability while contacting with the lithium anode and most of the cathode materials. In this paper, the crystal structure, Li-ion transport mechanism, preparation method, and element doping of LLZO are introduced in detail based on the research progress in recent years. Then, the development prospects and challenges of LLZO as applied to ASSBs are discussed.

Design and Control of Bi-directional DC/DC converter for 30kW fuel cell power system

Xiao Li,Wenping Zhang,Haijin Li,Ren Xie,Dehong Xu 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5

Fuel cell (FC) power system is considered as an alternative energy power generation system in the future. This paper studies the bidirectional DC/DC converter for a 30㎾ three-phase fuel cell power system. The FC power system is sensitive to load characteristics in stand-alone mode, because rapid change or unbalance of the three-phase load will endanger the safety and expectancy of fuel cell. The bidirectional DC/DC converter with energy storage component is used to provide the dynamic power to avoid fast changing in fuel cell output. In addition, it acts as DC bus capacitors to absorb the low frequency current ripple. Therefore, fuel cell is separated from the low frequency current ripple and large DC bus electrolytic capacitors can be eliminated. Through investigating topology of the bidirectional DC/DC converter, three-level bidirectional DC/DC converter (TLBD) is used for the 30㎾ fuel cell power system. The design and control of the TL-DB is described. TL-DB with its control strategy is verified by the experimental results.

UAV-Based Remote Sensing and Risk Assessment of Rockfalls in Guangzhou, China

( Wenping Gong ),( Zhan Cheng ),( Bing Li ),( Huiming Tang ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

Unmanned Aerial Vehicle (UAV) technique has been extensively applied in geohazards assessment. In this study, we illustrate the advantages of the UAV technique in the remote sensing and risk assessment of rockfalls, through a case study of the rockfalls located in Guangzhou, China; in which, the UAV images collected are adopted for identifying both potential rockfalls and geohazards bearing bodies. On the basis of a visual inspection of the high-resolution aerial photographs, the potential rockfalls are readily identified. Then, the post-failure runout behavior of the identified rockfalls is analyzed with the numerical software of particle flow code (PFC). Due to the inherent uncertainty in the determination of the micro-parameters in the PFC models, the micro-parameters required in the PFC modelling are calibrated as random variables. With the aid of the Monte Carlo simulation (MCS), the distributions of the runout distance and the velocity of the rockfalls could be obtained. From there, the zones that might be impacted by the rockfalls and the destructive forces on the potential geohazards bearing bodies (i.e., buildings) in these zones can be evaluated. Further, the geohazards bearing bodies in the zones that are impacted by the rockfalls are recognized with an automated image recognition model, which is based upon a deep learning-based image recognition technique of RetinaNet. On the basis of the post-failure runout behavior analysis of the rockfalls and the geohazards bearing bodies recognized, a rapid risk assessment of the rockfalls in the studied region can be conducted.

Transcriptome analysis of Dioscorea zingiberensis identifies genes involved in diosgenin biosynthesis

Wenping Hua,Weiwei Kong,XiaoYan Cao,Chen Chen,Qian Liu,Xiangmin Li,Zhezhi Wang 한국유전학회 2017 Genes & Genomics Vol.39 No.5

Dioscorea zingiberensis is the main plant source of diosgenin, a precursor for the production of steroid hormones used in the pharmaceutical industry. The extraction process of diosgenin from D. zingiberensis can generate high-acid and high-strength wastewater on a large scale and can threaten the environment. Bioengineering microorganisms to produce diosgenin is an effective way to avoid pollution. However, little is known about the genes that are involved in the biosynthesis of diosgenin. We obtained 85,010 unigenes (average length of 1142 bases) from the D. zingiberensis transcriptome through RNAseq. A large number of unigenes (59,368; 69.83%) were annotated, and 2488 unigenes were assigned to 27 secondary- metabolite pathways. In our database, 66 unigenes encoding up to 40 key enzymes were found to be present in diosgenin biosynthesis pathways. In addition, we found 203 unigenes encoding CYP450 proteins and 47 unigenes encoding UGT proteins that may be involved in modifications of a downstream pathway. The expression patterns of key diosgenin biosynthesis genes were studied to identify the most important members of the enzyme family. These results add to the available genetic data of D. zingiberensis and lay the foundation for the further production of diosgenin using genetic engineering.

Optimal Location of Piles in Stabilizing Slopes Based on a Simplified Double-row Piles Model

Changdong Li,Wenqiang Chen,Yingjie Song,Wenping Gong,Qihua Zhao 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.2

Embedding single-row piles is often adopted to stabilize slopes in engineering practice. However, for large-scale and complex slopes, single-row piles might not be able to stabilize the slope; rather, double-row piles, even multirow piles, should be adopted. Currently, the optimal locations of double-row stabilizing piles considering local instability of the slope have rarely been studied. In this paper, a simplified analytical model used to analyze double-row pile stabilized slopes is proposed, where the local failure of the slope above the first row of piles is considered. Through the kinematic approach of limit analysis combined with the strength reduction technique, the required resistance forces provided by double-row piles respectively are derived for different pile locations denoted by the rotational angle. Moreover, a framework is developed for analyzing the optimal locations of multirow piles considering multistage potential slip surfaces. The results of an illustrative example are presented, and the reasonableness of the proposed method is verified. It is concluded that the optimal locations of double-row piles lie within middle-lower part of the corresponding stabilized part of the slope. Finally, discussion illustrates the influences of the seismic effects and soil shear strength parameters on the derived optimal pile locations. This study provides novel scientific insight into the optimized design of stabilizing pile locations in engineering practice.

Optimal design of a V-type consequent-pole motor with shifted PMs for reducing the PM usage and the torque ripple

Mingjie Li(이명걸),Wenping Chai(차이원핑),Byung-il Kwon(권병일) 대한전기학회 2020 대한전기학회 학술대회 논문집 Vol.2020 No.7

Landslide susceptibility mapping at Gongliu county, China using artificial neural network and weight of evidence models

Qiqing Wang,Wenping Li,Maolin Xing,Yanli Wu,Yabing Pei,Dongdong Yang,Hanying Bai 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.5

The aim of this study was to apply and to verify the use of artificial neural network (ANN) and weight of evidence (WoE) models to landslide susceptibility mapping in the Gongliu county, China, using a geographic information system (GIS). For this aim, in this study, a landslide inventory map was prepared using earlier reports and aerial photographs as well as by carrying out field surveys. A total of 163 landslides (70% out of 233 detected landslides) were randomly selected for model training, and the remaining 70 landslides (30%) were used for the model validation. Then, a total number of twelve landslide conditioning factors, such as slope angle, slope aspect, general curvature, plan curvature, profile curvature, altitude, distance to rivers, distance to roads, lithology, rainfall, normalized difference vegetation index (NDVI), and sediment transport index (STI), were used in the analysis. Landslide hazardous areas were analyzed and mapped using the landslide-occurrence factors by ANN and WoE models. Finally the output maps were validated using the area under the curve (AUC) method. The validation results showed that the ANN model with a success rate of 82.51% and predictive accuracy of 77.31% performs better than WoE (success rate, 79.82%; predictive accuracy, 74.59%) model. Overall, both models showed almost similar results. Therefore, the two landslide susceptibility maps obtained were successful and can be useful for preliminary general land use planning and hazard mitigation purpose.

FACILE SOLVOTHERMAL SYNTHESIS OF MESOSTRUCTURED CHITOSAN-COATED Fe 3 O 4 NANOPARTICLES AND ITS FURTHER MODIFICATION WITH FOLIC ACID FOR IMPROVING TARGETED DRUG DELIVERY

MAO SHEN,CHENGLIN WU,WENPING JIA,CHENGHONG LI,ZHILI ZHANG,YANGMIN JIN,GUODONG FAN,CAIPING LIN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.7

Mesostructured chitosan-coated Fe 3 O 4 nanoparticles (CS-coated Fe 3 O 4 NPs) were synthesizedby a facile one-step solvothermal method via using chitosan as a surface-modi¯cation agent. Subsequently, the surfaces of CS-coated Fe 3 O 4 NPs were successfully conjugated with folic acid(FA) molecules to obtain FA – CS-coated Fe 3 O 4 NPs for improving targeted drug delivery. Themorphology, chemical component and magnetic property of as-prepared composite nanoparticleswere characterized by Fourier transform infrared spectroscopy (FTIR), X-ray di®raction (XRD),dynamic light scattering (DLS), scanning transmission electron microscopy (SEM), transmissionelectron microscopy (TEM), thermal gravimetric analysis (TGA) and vibrating sample magne-tometer (VSM). Furthermore, doxorubicin hydrochloride (DOX) as a model drug was encap-sulated for investigating drug release pattern in vitro. The results show that the magnetizationsaturation value of FA – CS-coated Fe 3 O 4 NPs was about 28.5 emu/g, exhibiting super-paramagnetic properties and mesostructure. DOX could be loaded to FA – CS-coated Fe 3 O 4 NPswith high capacity about 27.9%, and the release rate of DOX could be adjusted by the pH value. This work demonstrates that the prepared magnetic nanoparticles have potential applications inthe treatment of cancer as targeting drug delivery carriers.

Cryptotanshinone inhibits TNF-α-induced LOX-1 expression by suppressing reactive oxygen species (ROS) formation in endothelial cells

Xiaoli Ran,Wenwen Zhao,Wenping Li,Jingshan Shi,Xiuping Chen 대한생리학회-대한약리학회 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.4

Cryptotanshinone (CPT) is a natural compound isolated from traditional Chinese medicine Salvia miltiorrhiza Bunge. In the present study, the regulatory effect and potential mechanisms of CPT on tumor necrosis factor alpha (TNF-α) induced lectin-like receptor for oxidized low density lipoprotein (LOX-1) were investigated. Human umbilical vein endothelial cells (HUVECs) were cultured and the effect of TNF-α on LOX-1 expression at mRNA and protein levels was determined by Real-time PCR and Western blotting respectively. The formation of intracellular ROS was determined with fluorescence probe CM-DCFH2-DA. The endothelial ox-LDL uptake was evaluated with DiI-ox-LDL. The effect of CPT on LOX-1 expression was also evaluated with SD rats. TNF-α induced LOX-1 expression in a dose- and time- dependent manner in endothelial cells. TNF-α induced ROS formation, phosphorylation of NF-κB p65 and ERK, and LOX-1 expression, which were suppressed by rotenone, DPI, NAC, and CPT. NF-κB inhibitor BAY11-7082 and ERK inhibitor PD98059 inhibited TNF-α-induced LOX-1 expression. CPT and NAC suppressed TNF-α-induced LOX-1 expression and phosphorylation of NF-κB p65 and ERK in rat aorta. These data suggested that TNF-α induced LOX-1 expression via ROS activated NF-κB/ERK pathway, which could be inhibited by CPT. This study provides new insights for the anti-atherosclerotic effect of CPT.

Cryptotanshinone inhibits TNF-α-induced LOX-1 expression by suppressing reactive oxygen species (ROS) formation in endothelial cells

Ran, Xiaoli,Zhao, Wenwen,Li, Wenping,Shi, Jingshan,Chen, Xiuping The Korean Society of Pharmacology 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.4

Cryptotanshinone (CPT) is a natural compound isolated from traditional Chinese medicine Salvia miltiorrhiza Bunge. In the present study, the regulatory effect and potential mechanisms of CPT on tumor necrosis factor alpha ($TNF-{\alpha}$) induced lectin-like receptor for oxidized low density lipoprotein (LOX-1) were investigated. Human umbilical vein endothelial cells (HUVECs) were cultured and the effect of $TNF-{\alpha}$ on LOX-1 expression at mRNA and protein levels was determined by Real-time PCR and Western blotting respectively. The formation of intracellular ROS was determined with fluorescence probe $CM-DCFH_2-DA$. The endothelial ox-LDL uptake was evaluated with DiI-ox-LDL. The effect of CPT on LOX-1 expression was also evaluated with SD rats. $TNF-{\alpha}$ induced LOX-1 expression in a dose- and time- dependent manner in endothelial cells. $TNF-{\alpha}$ induced ROS formation, phosphorylation of $NF-{\kappa}B$ p65 and ERK, and LOX-1 expression, which were suppressed by rotenone, DPI, NAC, and CPT. $NF-{\kappa}B$ inhibitor BAY11-7082 and ERK inhibitor PD98059 inhibited $TNF-{\alpha}-induced$ LOX-1 expression. CPT and NAC suppressed $TNF-{\alpha}-induced$ LOX-1 expression and phosphorylation of $NF-{\kappa}B$ p65 and ERK in rat aorta. These data suggested that $TNF-{\alpha}$ induced LOX-1 expression via ROS activated $NF-{\kappa}B/ERK$ pathway, which could be inhibited by CPT. This study provides new insights for the anti-atherosclerotic effect of CPT.