http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
ADPRT Val762Ala and XRCC1 Arg194Trp Polymorphisms and Risk of Gastric Cancer in Sichuan of China
Wen, Yuan-Yuan,Pan, Xiong-Fei,Loh, Marie,Tian, Zhi,Yang, Shu-Juan,Lv, Si-Han,Huang, Wen-Zhi,Huang, He,Xie, Yao,Soong, Richie,Yang, Chun-Xia Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Objective: Gastric cancer remains a major health problem in China. We hypothesized that XRCC1 Arg194Trp and ADPRT Val762Ala may be associated with risk. Methods: We designed a multicenter 1:1 matched case-control study of 307 pairs of gastric cancers and controls between October 2010 and August 2011. XRCC1 Arg194Trp and ADPRT Val762Ala were sequenced, and demographic data as well as lifestyle factors were collected using a self-designed questionnaire. Results: Individuals carrying XRCC1 Trp/Trp or Arg/Trp variant genotype had a significantly increased risk of gastric cancer (OR, 1.718; 95% CI, 1.190-2.479), while the OR for ADPRT Val762Ala variant genotype (Ala/Ala or Val/Ala) was 1.175 (95% CI, 0.796-1.737). No gene-gene or gene-environment interactions were found. In addition, family history of cancer and drinkers proportion were higher among cases than among controls (P<0.05). Conclusions: XRCC1 194 Arg/Trp or Trp/Trp genotype, family history of cancer, and drinking are suspected risk factors of gastric cancer from our study. Our findings may offer insight into further similar large gene-environment and gene-gene studies in this region.
Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats
Wen-Wen Yan,Li-Hua Yao,Chong Chen,Hai-Xia Wang,Chu-Hua Li,Jun-Ni Huang,Peng Xiao,Cheng-Yi Liu 대한배뇨장애요실금학회 2015 International Neurourology Journal Vol.19 No.4
Purpose: Modafinil is a wake-promoting agent that has been proposed to improve cognitive performance at the preclinical and clinical levels. Since there is insufficient evidence for modafinil to be regarded as a cognitive enhancer, the aim of this study was to investigate the effects of chronic modafinil administration on behavioral learning in healthy adult rats. Methods: Y-maze training was used to assess learning performance, and the whole-cell patch clamp technique was used to assess synaptic transmission in pyramidal neurons of the hippocampal CA1 region of rats. Results: Intraperitoneal administration of modafinil at 200 mg/kg or 300 mg/kg significantly improved learning performance. Furthermore, perfusion with 1mM modafinil enhanced the frequency and amplitude of spontaneous postsynaptic currents and spontaneous excitatory postsynaptic currents in CA1 pyramidal neurons in hippocampal slices. However, the frequency and amplitude of spontaneous inhibitory postsynaptic currents in CA1 pyramidal neurons were inhibited by treatment with 1mM modafinil. Conclusions: These results indicate that modafinil improves learning and memory in rats possibly by enhancing glutamatergic excitatory synaptic transmission and inhibiting GABAergic (gamma-aminobutyric acid-ergic) inhibitory synaptic transmission.
Tests of reinforced concrete deep beams
Wen-Yao Lu,Hsin-Tai Hsiao,Chun-Liang Chen,Shu-Min Huang,Ming-Che Lin 사단법인 한국계산역학회 2015 Computers and Concrete, An International Journal Vol.15 No.3
This study reports the test results of twelve reinforced concrete deep beams. The deep beams were tested with loads applied through and supported by columns. The main variables studied were the shear span-to-depth ratios, and the horizontal and vertical stirrups. The shear strengths can be effectively enhanced for deep beams reinforced with both horizontal and vertical stirrups. The test results indicate the shear strengths of deep beams increase with the decrease of the shear span-to-depth ratios. The normalized shear strengths of the deep beams did not increase proportionally with an increase in effective depth. An analytical method for predicting the shear strengths of deep beams is proposed in this study. The shear strengths predicted by the proposed method and the strut-and-tie model of the ACI Code are compared with available test results. The comparison shows the proposed method can predict the shear strengths of reinforced concrete deep beams more accurately than the strut-and-tie model of the ACI Code.
충적과정중 미국인삼 종자의 생리 및 생화학적 지표에 관한 동태학적 연구 I
Huang, Yao-Ge,Li, Xiang-Gao,Cui, Shu-Yu,Yu, Wen-Bo,Kuang, Ya-Lan,Yan, Jie-kun,Yang, Ji-Xiang,Liu, Ren-Song,Kim, Hack-Seang The Korean Society of Ginseng 1997 Journal of Ginseng Research Vol.21 No.1
Dynamic parameters of biochemistry including the contents of soluble carbohydrate (SC) , crude fat (CF) , fatty arid (FA) and soluble protein (SP) in American send (Panax qufnquelolium L.) seed are reported in the present paper. When embryo ratio (ER) increased from 7.31 to 20.48%, the SC content decreased from 4.08 to 1.16%. After that, SC content changed little. The CF content decreased successively from 34.50 to 14.40% from the beginning to the end during the embryo afterripening. The changes of FA content did not correlate with that of ER and the changing range of SP content was not large during the seed stratification. All of these may provide some information for understanding the dormancy mechanisms of American seng seed.
충적과정중 미국인삼 종자의 생리 및 생화하적 지표에 관한 동태학적 연구 III
Huang, Yao-Ge,Li, Xiang-Gao,Kuang, Ya-Lan,Yan, Jie-Kun,Cui, Shu-Yu,Yu, Wen-Bo,Yang, Ji-Xiang,Liu, Ren-Song,Kim, Hack-Seang 고려인삼학회 1997 Journal of Ginseng Research Vol.21 No.1
Dynamic parameters of biochemistry including the POD (peroxidase) activity, contents of DNA and RNA, isozymes of POD and ES (esterase) in American send (Panax quinquefolium L.) seed are reported in the present paper. The dynamic changes of POD activity proved that the PAS (physiological afterripening stage) is a stage in which some substances are prepared for seed germination. The POD activity correlated with ER (embryo ratio) significantly DNA content changed little only within 0.0036∼0.013 mg/ml, which did not correlate with ER. RNA content changed from 0.1539 to 1.0313 mg/ml and correlated significantly with RE during all of the embryo afterripening. None of the POD isozyme band was obtained in ESGS (embryo slowly growth stage), but five bands in ERGS (embryo rapidly growth stage) and six bands in PAS. Four bands of ES isozymes were obtained in ESGS, but six bands in ERGS, particularly, the content of ES isozymes increased in PAS. All of these may provide some information for understanding the dormancy mechanisms of American song seed.
Xin Yao,CHANGCHANG MA,Hai Huang,Zhi Zhu,Hongjun Dong,Chunxiang Li,Wenli Zhang,Yongsheng Yan,Yang Liu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.3
In this paper, the biomass carbon quantum dots (CQDs) modified flower-like BiOI (CQDs/BiOI) composite photocatalyst was synthesized by a facile solvothermal method. Compared with the pristine BiOI, the biomass CQDs/BiOI exhibited outstanding photocatalytic activity for degradation of the typical methylene blue (MB) under visible light irradiation since the biomass CQDs could act as electron acceptors to effectively facilitate the separation efficiency of photon-generated carriers and prolong their lifetime. Furthermore, the mechanism detection experiment showed that the ·O2 - and H+ were major activity species, and the photocatalytic electron transfer mechanism was further investigated. This work provided a new insight into biomass CQDs effects and took an important step toward the development of improving Bi-based semiconductor photocatalyst activity.
Membrane surface charge and morphological and mechanical properties of young and old erythrocytes
Xing-Yao Chen,Yao-Xiong Huang,Wen-jing Liu,Zhi-jian Yuan 한국물리학회 2007 Current Applied Physics Vol.7 No.s1
ditions were studied as a function of cell age. The young and old cells were separated from fresh rabbit blood by using Percoll densitygradients. A novel multi-dimensional microscope was employed to perform real-time, non-invasivein situmeasurements on the mem-brane bending elastic modulus and the cell shape and size. A phase-analysis micro-electrophoresis laser scattering technique was usedto measure the surface charge density. The results show that the membrane Zeta potential of red blood cells is reduced when they become.
Qianwen Huang,Daizhi Yang,Hongrong Deng,Hua Liang,Xueying Zheng,Jinhua Yan,Wen Xu,Xiangwen Liu,Bin Yao,Sihui Luo,Jianping Weng 대한당뇨병학회 2022 Diabetes and Metabolism Journal Vol.46 No.1
Background: Both type 1 diabetes mellitus (T1DM) and metabolic syndrome (MetS) are associated with an elevated risk of morbidity and mortality yet with increasing heterogeneity. This study primarily aimed to evaluate the prevalence of MetS among adult patients with T1DM in China and investigate its associated risk factors, and relationship with microvascular complications.Methods: We included adult patients who had been enrolled in the Guangdong T1DM Translational Medicine Study conducted from June 2010 to June 2015. MetS was defined according to the updated National Cholesterol Education Program criterion. Logistic regression models were used to estimate the odds ratio (OR) for the association between MetS and the risk of diabetic kidney disease (DKD) and diabetic retinopathy (DR).Results: Among the 569 eligible patients enrolled, the prevalence of MetS was 15.1%. While female gender, longer diabetes duration, higher body mass index, and glycosylated hemoglobin A1c (HbA1c) were risk factors associated with MetS (OR, 2.86, 1.04, 1.14, and 1.23, respectively), received nutrition therapy education was a protective factor (OR, 0.46). After adjustment for gender, age, diabetes duration, HbA1c, socioeconomic and lifestyle variables, MetS status was associated with an increased risk of DKD and DR (OR, 2.14 and 3.72, respectively; both P<0.05).Conclusion: Although the prevalence of MetS in adult patients with T1DM in China was relatively low, patients with MetS were more likely to have DKD and DR. A comprehensive management including lifestyle modification might reduce their risk of microvascular complications in adults with T1DM.