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Lin Min Jung,Chang Shen Chang,Chen Tzu Jou,Lin Wei Chih,Peng Shao Yu,Lee Tzu Tai 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.9
Objective: The purpose of this study was to investigate whether goose growth and feather characteristics are influenced by their line and feeding surroundings, inclusive of floor materials and types, since there are no reports regarding these factors. Methods: The 240 White Roman geese which were hatched and sex identified came from 3 commercial goose farms. They were randomly distributed to 24 pens depending on a completely random design. The study continued for 13 weeks and included 3 lines of commercial geese and 2 floor types (cement strip floor [CSF] or cement floor [CF]). Results: The day one gosling weight from A farm was lower than other two farms (96 g vs 107 and 115 g; p<0.001). Afterwards, the body weight, back length, keel length, chest girth and main wing feather length among 3 farms showed no significance difference prior to 12 weeks. The CF group showed heavier body weight, shorter back length, longer keel length, shorter chest girth and shorter main wing feather length than the CSF group prior to 12 weeks. The down weight in the CF was heavier than the CSF group (57.1 g vs 41.8 g; p<0.01) prior to 13 weeks. Conclusion: The body weight showed the positive relations for dry feather weight (r = 0.59), down weight (r = 0.69), percent of the down weight of live body weight prior to 13 weeks (r = 0.61).
( Chun-chi Lin ),( Shu-chen Wei ),( Been-ren Lin ),( Wen-sy-tsai ),( Jinn-shiun Chen ),( Tzu-chi Hsu ),( Wei-chen Lin ),( Tien-yu Huang ),( Te-hsin Chao ),( Hung-hsin Lin ),( Jau-min Wong ),( Jen-kou 대한장연구학회 2016 Intestinal Research Vol.14 No.3
Background/Aims: With the recent progress in medical treatment, surgery still plays a necessary and important role in treating ulcerative colitis (UC) patients. In this study, we analyzed the surgical results and outcomes of UC in Taiwan in the recent 20 years, via a multi-center study through the collaboration of Taiwan Society of IBD. Methods: A retrospective analysis of surgery data of UC patients from January 1, 1995, through December 31, 2014, in 6 Taiwan major medical centers was conducted. The patients’ demographic data, indications for surgery, and outcome details were recorded and analyzed. Results: The data of 87 UC patients who received surgical treatment were recorded. The median post-operative follow-up duration was 51.1 months and ranged from 0.4 to 300 months. The mean age at UC diagnosis was 45.3±16.0 years and that at operation was 48.5±15.2 years. The 3 leading indications for surgical intervention were uncontrolled bleeding (16.1%), perforation (13.8%), and intractability (12.6%). In total, 27.6% of surgeries were performed in an emergency setting. Total or subtotal colectomy with rectal preservation (41.4%) was the most common operation. There were 6 mortalities, all due to sepsis. Emergency operation and low pre-operative albumin level were significantly associated with poor survival (P =0.013 and 0.034, respectively). Conclusions: In the past 20 years, there was no significant change in the indications for surgery in UC patients. Emergency surgeries and low pre-operative albumin level were associated with poor survival. Therefore, an optimal timing of elective surgery for people with poorly controlled UC is paramount.
Tzu Yu Lin,Cheng Wei Lu,Shu-Kuei Huang,Su-Jane Wang 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.2
This study investigated the effects and possible mechanism of ferulic acid, a naturally occurring phenolic compound, on endogenous glutamate release in the nerve terminals of the cerebral cortex in rats. Results show that ferulic acid inhibited the release of glutamate evoked by the K+ channel blocker 4-aminopyridine (4-AP). The effect of ferulic acid on the evoked glutamate release was prevented by chelating the extracellular Ca2+ ions, but was insensitive to the glutamate transporter inhibitor DL-threo-beta-benzyl-oxyaspartate. Ferulic acid suppressed the depolarization-induced increase in a cytosolic-free Ca2+ concentration, but did not alter 4-AP–mediated depolarization. Furthermore, the effect of ferulic acid on evoked glutamate release was abolished by blocking the Cav2.2 (N-type) and Cav2.1 (P/Q-type) channels, but not by blocking ryanodine receptors or mitochondrial Na+/Ca2+ exchange. These results show that ferulic acid inhibits glutamate release from cortical synaptosomes in rats through the suppression of presynaptic voltage-dependent Ca2+ entry.
Tzu-Yi Lin,Eugene Yu-Chuan Kang,Shih-Chieh Shao,Edward Chia-Cheng Lai,Sunir J. Garg,Kuan-Jen Chen,Je-Ho Kang,Wei-Chi Wu,Chi-Chun Lai,Yih-Shiou Hwang 대한당뇨병학회 2023 Diabetes and Metabolism Journal Vol.47 No.3
Background: To compare risk of diabetic retinopathy (DR) between patients taking sodium-glucose cotransporter-2 inhibitors (SGLT2is) and those taking glucagon-like peptide-1 receptor agonists (GLP1-RAs) in routine care.Methods: This retrospective cohort study emulating a target trial included patient data from the multi-institutional Chang Gung Research Database in Taiwan. Totally, 33,021 patients with type 2 diabetes mellitus using SGLT2is and GLP1-RAs between 2016 and 2019 were identified. 3,249 patients were excluded due to missing demographics, age <40 years, prior use of any study drug, a diagnosis of retinal disorders, a history of receiving vitreoretinal procedure, no baseline glycosylated hemoglobin, or no follow-up data. Baseline characteristics were balanced using inverse probability of treatment weighting with propensity scores. DR diagnoses and vitreoretinal interventions served as the primary outcomes. Occurrence of proliferative DR and DR receiving vitreoretinal interventions were regarded as vision-threatening DR.Results: There were 21,491 SGLT2i and 1,887 GLP1-RA users included for the analysis. Patients receiving SGLT2is and GLP-1 RAs exhibited comparable rate of any DR (subdistribution hazard ratio [SHR], 0.90; 95% confidence interval [CI], 0.79 to 1.03), whereas the rate of proliferative DR (SHR, 0.53; 95% CI, 0.42 to 0.68) was significantly lower in the SGLT2i group. Also, SGLT2i users showed significantly reduced risk of composite surgical outcome (SHR, 0.58; 95% CI, 0.48 to 0.70).Conclusion: Compared to those taking GLP1-RAs, patients receiving SGLT2is had a lower risk of proliferative DR and vitreoretinal interventions, although the rate of any DR was comparable between the SGLT2i and GLP1-RA groups. Thus, SGLT2is may be associated with a lower risk of vision-threatening DR but not DR development.
Tzu-Chau Chen,Chao-Tsai Huang,Yan-Chen Chiu,Wei-Da Wang,Cheng-Li Hsu,Chen-Yang Lin,Lung-Wen Kao 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
Runner system plays a very important role in injection molding process. A quality runner design is helpful in improving product qualities and saving material. However, traditional cold runner systems have certain inherent issues. Moreover, poor product cosmetics are commonly seen with the use of traditional cold runners. As a result, hot runner technology has been widely applied. On the other hand, It has been one of the green molding solutions for material/energy saving and clean environments. But the mechanism behind the hot runner system is too complicated to be fully understood. There exist some critical issues currently. As a result, the simulation technolgy is highly needed to examine hot runner designs before the real manufacturing. Through simulation analyses, designers and manufafctuers are able to catch the potential issues on their hot runner systems and revise their designs. Hot runner simulation technology helps with the investigations into the behavior in hot runner system. In this paper, a true 3D numerical method is proposed and applied to investigate the temperature behavior in a real hot runner system for PC material. The experiment is conducted and the simulating result is compared with that from the experiment for the validation purpose.
Cheng Wei Lu,Shu-Kuei Huang,Tzu Yu Lin,Su-Jane Wang 대한약리학회 2018 The Korean Journal of Physiology & Pharmacology Vol.22 No.3
Echinacoside, an active compound in the herb Herba Cistanche, has been reported to inhibit glutamate release. In this study, we investigated the effects of echinacoside on spontaneous excitatory synaptic transmission changes induced by 4-aminopyridine (4-AP), by using the in vitro rat hippocampal slice technique and whole-cell patch clamp recordings from CA3 pyramidal neurons. Perfusion with echinacoside significantly suppressed the 4-AP-induced epileptiform activity in a concentration-dependent manner. Echinacoside reduced 4-AP-induced increase in frequency of spontaneous excitatory postsynaptic currents (sEPSCs) but it did not affect the amplitude of sEPSCs or glutamate-activated currents, implicating a presynaptic mechanism of action. Echinacoside also potently blocked sustained repetitive firing, which is a basic mechanism of antiepileptic drugs. These results suggest that echinacoside exerts an antiepileptic effect on hippocampal CA3 pyramidal neurons by simultaneously decreasing glutamate release and blocking abnormal firing synchronization. Accordingly, our study provides experimental evidence that echinacoside may represent an effective pharmacological agent for treating epilepsy.
The simple and easy way to manufacture counter electrode for dye-sensitized solar cells
Jo-Lin Lan,Yung-Yun Wang,Chi-Chao Wan,Tzu-Chien Wei,Hsien-Ping Feng,Chao Peng,Hai-Peng Cheng,Ya-Huei Chang,Wen-Chi Hsu 한국물리학회 2010 Current Applied Physics Vol.10 No.2
We previously developed poly-N-vinyl-2-pyrrolidone (PVP)-capped Pt nanoclusters on ITO glass via a simple ‘‘2-step dip coating process” as counter electrode for DSSC. This new counter electrode was examined by transmission electron microscopy (TEM), inductively coupled plasma-atomic emission spectroscopy (ICP-AES), electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and current–voltage curve (I–V curve). The TEM results revealed that PVP-capped Pt nanoclusters’ size is about 3 nm, and the amount of Pt deposited on ITO glass is about 5 ㎍/㎠. Comparing with sputtered Pt and Solaronix thermal cluster Pt-catalyst T/SP, the PVP-capped Pt counter electrode has lower amount of Pt deposited on TCO glass,more positive potential of tri-iodide reduction, and better performance for the charge-transfer resistance (RCT) and the cell efficiency (g).
Yu-Lin Fang,Tzu-Hsuan Huang,Chia-Chin Chiang,Chao-Wei Wu 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.73 No.9
This study used an inductively coupled plasma (ICP) dry etching process with a metal amplitude mask to fabricate a double-side notched long-period fiber grating (DNLPFG) for loading sensing. The DNLPFG exhibited increasing resonance attenuation loss for a particular wavelength when subjected to loading. When the DNLPFG was subjected to force loading, the transmission spectra were changed, showing a with wavelength shift and resonance attenuation loss. The experimental results showed that the resonant dip of the DNLPFG increased with increasing loading. The maximum resonant dip of the 40-m DNLPFG sensor was 26:522 dB under 0.049-N loading, and the largest force sensitivity was 436:664 dB/N. The results demonstrate that the proposed DNLPFG has potential for force sensing applications.
( Meng Tzu Weng ),( Shu Chen Wei ),( Chun Che Lin ),( Yuk Min Tsang ),( Chia Tung Shun ),( Jann Yuan Wang ),( Ming Jium Shieh ),( Cheng Yi Wang ),( Jau Min Wong ) 대한장연구학회 2015 Intestinal Research Vol.13 No.1
Since Taiwan is an endemic area for tuberculosis (TB), differential diagnosis between the intestinal TB and Crohn`s disease is an important issue. The steering committee of Taiwan Society of Inflammatory Bowel Disease (TSIBD) has arranged a seminar accordingly on May 24th, 2014 and the different point of views by gastroenterologist, radiologist, pathologist and infectious dis-ease specialist were suggested to help the proper diagnosis and management of these two diseases. (Intest Res 2015;13:6-10)